ES2503621T3 - Métodos para detectar trastornos autoinmunitarios - Google Patents
Métodos para detectar trastornos autoinmunitarios Download PDFInfo
- Publication number
- ES2503621T3 ES2503621T3 ES12179717.9T ES12179717T ES2503621T3 ES 2503621 T3 ES2503621 T3 ES 2503621T3 ES 12179717 T ES12179717 T ES 12179717T ES 2503621 T3 ES2503621 T3 ES 2503621T3
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medical Informatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Un método para diagnosticar lupus eritematoso sistémico en un sujeto, comprendiendo dicho método determinar si el sujeto comprende una célula que expresa una combinación de genes a un nivel superior al nivel de expresión de los genes respectivos en una muestra de referencia normal, en donde la combinación de genes incluye IFI44L, CIG5 e IFI44, y en el que la presencia de expresión aumentada de IFI44L, CIG5 e IFI44 en dicha célula indica que el sujeto tiene lupus eritematoso sistémico
Description
Claims (1)
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imagen1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79439306P | 2006-04-24 | 2006-04-24 | |
US794393P | 2006-04-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2503621T3 true ES2503621T3 (es) | 2014-10-07 |
Family
ID=38340088
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES12179733.6T Active ES2462526T3 (es) | 2006-04-24 | 2007-04-24 | Métodos y composiciones para detectar trastornos autoinmunitarios |
ES09003931.4T Active ES2471444T3 (es) | 2006-04-24 | 2007-04-24 | Métodos y composiciones para detectar trastornos autoinmunitarios |
ES12179717.9T Active ES2503621T3 (es) | 2006-04-24 | 2007-04-24 | Métodos para detectar trastornos autoinmunitarios |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES12179733.6T Active ES2462526T3 (es) | 2006-04-24 | 2007-04-24 | Métodos y composiciones para detectar trastornos autoinmunitarios |
ES09003931.4T Active ES2471444T3 (es) | 2006-04-24 | 2007-04-24 | Métodos y composiciones para detectar trastornos autoinmunitarios |
Country Status (11)
Country | Link |
---|---|
US (5) | US20080057503A1 (es) |
EP (4) | EP2044213A2 (es) |
JP (2) | JP5784272B2 (es) |
KR (1) | KR101464386B1 (es) |
CN (2) | CN101473045B (es) |
AU (1) | AU2007244868B2 (es) |
CA (1) | CA2649918C (es) |
DK (1) | DK2557180T3 (es) |
ES (3) | ES2462526T3 (es) |
PL (1) | PL2557180T3 (es) |
WO (1) | WO2007127756A2 (es) |
Families Citing this family (24)
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EP2044213A2 (en) * | 2006-04-24 | 2009-04-08 | Genentech, Inc. | Methods and compositions for detecting autoimmune disorders |
US20100285458A1 (en) * | 2007-01-25 | 2010-11-11 | Danute Bankaitis-Davis | Gene Expression Profiling for Identification, Monitoring, and Treatment of Lupus Erythematosus |
EP2167679A4 (en) * | 2007-07-12 | 2011-01-12 | Brigham & Womens Hospital | COMPOSITIONS AND METHODS FOR DIAGNOSIS AND ASSESSMENT OF INFLAMMATORY MUSCLE DISEASES |
AU2009246180B2 (en) | 2008-05-14 | 2015-11-05 | Dermtech International | Diagnosis of melanoma and solar lentigo by nucleic acid analysis |
WO2009155559A1 (en) * | 2008-06-20 | 2009-12-23 | Medimmune Llc | Interferon alpha-induced pharmacodynamic markers |
WO2011085653A1 (zh) * | 2010-01-12 | 2011-07-21 | 中国科学院上海生命科学研究院 | 用于鉴定和治疗葛瑞夫兹氏病的方法和试剂盒 |
WO2011133474A2 (en) * | 2010-04-18 | 2011-10-27 | Beth Israel Deaconess Medical Center | Methods of predicting predisposition to or risk of kidney disease |
ES2372762B1 (es) * | 2010-07-02 | 2012-11-28 | Consejo Superior De Investigaciones Científicas (Csic) | Método y kit para la detección de la activación de interferón y la respuesta inflamatoria independiente de interferón. |
WO2012074396A1 (en) * | 2010-11-30 | 2012-06-07 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patiëntenzorg | Method for prognosticating the clinical response of a patient to b-lymphocyte inhibiting or depleting therapy in interferon driven diseases such as sle |
AU2012249601A1 (en) * | 2011-04-26 | 2013-05-09 | Genentech, Inc. | Compositions and method for treating autoimmune diseases |
WO2013101771A2 (en) | 2011-12-30 | 2013-07-04 | Genentech, Inc. | Compositions and method for treating autoimmune diseases |
WO2014032899A1 (en) * | 2012-08-31 | 2014-03-06 | Novo Nordisk A/S | Diagnosis and treatment of lupus nephritis |
US9867055B2 (en) * | 2014-04-30 | 2018-01-09 | Qualcomm Incorporated | Techniques for coordinating communications over an unlicensed radio frequency spectrum band |
CN105420347A (zh) * | 2014-08-21 | 2016-03-23 | 南京大学医学院附属鼓楼医院 | 一种用于系统性红斑狼疮的基因诊断试剂盒 |
WO2016026258A1 (en) * | 2014-08-22 | 2016-02-25 | Institute Of Biophysics, Chinese Academy Of Sciences | Methods and compositions for treating and/or preventing a disease or disorder associated with abnormal level and/or activity of the ifp35 family of proteins |
CN105316404B (zh) * | 2015-02-27 | 2017-02-22 | 中南大学湘雅二医院 | 系统性红斑狼疮生物标志物及其诊断试剂盒 |
KR101795689B1 (ko) * | 2015-04-30 | 2017-11-30 | 경희대학교 산학협력단 | 혈관 협착 질환 진단용 마커 및 이의 용도 |
CN106520970B (zh) * | 2016-11-24 | 2018-08-07 | 汕头大学医学院第一附属医院 | 用于诊断脑卒中的标志物 |
EP3450981A1 (en) * | 2017-08-28 | 2019-03-06 | Trizell GmbH | Btnl8 as a marker for tregs |
CA3090785A1 (en) | 2018-02-14 | 2019-08-22 | John Daniel Dobak Iii | Novel gene classifiers and uses thereof in non-melanoma skin cancers |
AU2019266226A1 (en) | 2018-05-09 | 2020-12-03 | Dermtech, Inc. | Novel gene classifiers and uses thereof in autoimmune diseases |
WO2020198229A1 (en) | 2019-03-26 | 2020-10-01 | Dermtech, Inc. | Novel gene classifiers and uses thereof in skin cancers |
CN111351946B (zh) * | 2020-03-19 | 2023-08-18 | 中南大学湘雅二医院 | 用于红斑狼疮分型的AIM2+CD4+Trm细胞检测试剂盒及其应用 |
CN112843222B (zh) * | 2021-01-21 | 2023-01-31 | 暨南大学 | Ankrd22蛋白在制备治疗或延缓自身免疫性疾病的产品中的应用 |
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EP2044213A2 (en) | 2006-04-24 | 2009-04-08 | Genentech, Inc. | Methods and compositions for detecting autoimmune disorders |
AU2012249601A1 (en) | 2011-04-26 | 2013-05-09 | Genentech, Inc. | Compositions and method for treating autoimmune diseases |
-
2007
- 2007-04-24 EP EP07761227A patent/EP2044213A2/en not_active Withdrawn
- 2007-04-24 DK DK12179717.9T patent/DK2557180T3/da active
- 2007-04-24 KR KR1020087028508A patent/KR101464386B1/ko active IP Right Grant
- 2007-04-24 CN CN200780023381.3A patent/CN101473045B/zh active Active
- 2007-04-24 ES ES12179733.6T patent/ES2462526T3/es active Active
- 2007-04-24 PL PL12179717T patent/PL2557180T3/pl unknown
- 2007-04-24 CA CA2649918A patent/CA2649918C/en active Active
- 2007-04-24 EP EP12179717.9A patent/EP2557180B1/en active Active
- 2007-04-24 JP JP2009507934A patent/JP5784272B2/ja active Active
- 2007-04-24 EP EP12179733.6A patent/EP2537943B1/en active Active
- 2007-04-24 ES ES09003931.4T patent/ES2471444T3/es active Active
- 2007-04-24 AU AU2007244868A patent/AU2007244868B2/en active Active
- 2007-04-24 WO PCT/US2007/067341 patent/WO2007127756A2/en active Application Filing
- 2007-04-24 US US11/739,606 patent/US20080057503A1/en not_active Abandoned
- 2007-04-24 CN CN201610423450.0A patent/CN106086175B/zh active Active
- 2007-04-24 EP EP09003931.4A patent/EP2080814B1/en active Active
- 2007-04-24 ES ES12179717.9T patent/ES2503621T3/es active Active
-
2010
- 2010-03-30 US US12/749,524 patent/US20100267033A1/en not_active Abandoned
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2011
- 2011-12-21 US US13/333,775 patent/US8962249B2/en active Active
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2013
- 2013-03-11 US US13/794,717 patent/US9139878B2/en active Active
- 2013-07-05 JP JP2013141938A patent/JP5912097B2/ja active Active
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2015
- 2015-09-02 US US14/843,890 patent/US20160097098A1/en not_active Abandoned
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