ES2478872T3 - Composición líquida que comprende una proteasa aspártica - Google Patents
Composición líquida que comprende una proteasa aspártica Download PDFInfo
- Publication number
- ES2478872T3 ES2478872T3 ES11156545.3T ES11156545T ES2478872T3 ES 2478872 T3 ES2478872 T3 ES 2478872T3 ES 11156545 T ES11156545 T ES 11156545T ES 2478872 T3 ES2478872 T3 ES 2478872T3
- Authority
- ES
- Spain
- Prior art keywords
- liquid composition
- aspartic protease
- count
- malate
- formate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C19/00—Cheese; Cheese preparations; Making thereof
- A23C19/02—Making cheese curd
- A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
- A23C19/0326—Rennet produced by fermentation, e.g. microbial rennet; Rennet produced by genetic engineering
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6402—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals
- C12N9/6405—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from non-mammals not being snakes
- C12N9/6413—Aspartic endopeptidases (3.4.23)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6478—Aspartic endopeptidases (3.4.23)
- C12N9/6483—Chymosin (3.4.23.4), i.e. rennin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/23—Aspartic endopeptidases (3.4.23)
- C12Y304/23004—Chymosin (3.4.23.4), i.e. rennin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Enzymes And Modification Thereof (AREA)
- Detergent Compositions (AREA)
- Dairy Products (AREA)
Abstract
Composición líquida que comprende: (i) una proteasa aspártica de Rhizomucor miehei y (ii) una sal inorgánica y (iii) un compuesto seleccionado de formiato, acetato, lactato, propionato, malato o fumarato composición en que: la concentración total de sorbato, benzoato y ésteres alquílicos de para-hidroxibenzoato es menor que 0,010 moles/l; el recuento en placa clásico <= 100 en 1 ml; recuento de levaduras <= 10 en 1 ml y recuento de mohos <= 10 en 1 ml y en la que el pH está entre 4,8 y 5,5 y en que la concentración de formiato, acetato, lactato, propionato, malato o fumarato o combinación de los mismos es al menos 0,1 moles/l.
Description
Claims (1)
-
imagen1 imagen2
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79144706P | 2006-04-13 | 2006-04-13 | |
EP06112649 | 2006-04-13 | ||
EP06112649 | 2006-04-13 | ||
US791447P | 2006-04-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2478872T3 true ES2478872T3 (es) | 2014-07-23 |
Family
ID=36950288
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES11156545.3T Active ES2478872T3 (es) | 2006-04-13 | 2007-04-12 | Composición líquida que comprende una proteasa aspártica |
Country Status (12)
Country | Link |
---|---|
US (1) | US20100009033A1 (es) |
EP (2) | EP2004820A1 (es) |
JP (1) | JP5557242B2 (es) |
CN (1) | CN101421397A (es) |
BR (1) | BRPI0709829A2 (es) |
DK (1) | DK2333056T3 (es) |
EA (1) | EA025412B1 (es) |
ES (1) | ES2478872T3 (es) |
MX (1) | MX2008013182A (es) |
NZ (1) | NZ571699A (es) |
PL (1) | PL2333056T3 (es) |
WO (1) | WO2007118838A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2617819B1 (en) | 2006-09-21 | 2016-04-27 | BASF Enzymes LLC | Phytases, nucleic acids encoding them and methods for making and using them |
AU2010215867B2 (en) | 2009-02-20 | 2016-03-31 | Danisco Us Inc. | Fermentation broth formulations |
CN101870967B (zh) * | 2010-07-22 | 2012-05-23 | 安泰生物工程股份有限公司 | 半连续发酵生产微生物凝乳酶的方法 |
WO2012127005A1 (en) | 2011-03-22 | 2012-09-27 | Dsm Ip Assets B.V. | Chymosin formulation |
CN103773751A (zh) * | 2012-10-22 | 2014-05-07 | 丰益(上海)生物技术研发中心有限公司 | 脂肪酶稳定剂 |
ES2685402T3 (es) | 2013-07-18 | 2018-10-08 | Chr. Hansen A/S | Composición de enzima proteasa aspártica para coagulación de leche |
CN103740685B (zh) * | 2013-10-11 | 2015-04-15 | 孟乙 | 利用米黑毛霉生产凝乳酶的方法 |
CN104480095A (zh) * | 2014-11-27 | 2015-04-01 | 广西大学 | 一种酶活力稳定的液态木瓜蛋白酶制剂 |
JP2017029129A (ja) * | 2015-07-30 | 2017-02-09 | 三菱化学フーズ株式会社 | プロテアーゼの活性維持方法およびプロテアーゼ溶液 |
WO2017089613A1 (en) | 2015-11-26 | 2017-06-01 | Csk Food Enrichment B.V. | Liquid composition comprising an aspartic protease having improved enzyme stability |
GB201520912D0 (en) | 2015-11-26 | 2016-01-13 | Csk Food Enrichment Bv | Liquid composition comprising an aspartic protease having improved enzyme stability |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK110031A (es) | 1965-12-02 | |||
US3763010A (en) * | 1971-06-10 | 1973-10-02 | Baxter Laboratories Inc | Stabilized microbial rennet |
US4348482A (en) * | 1978-05-22 | 1982-09-07 | Miles Laboratories, Inc. | Process for decreasing the thermal stability of microbial rennet |
IL87258A (en) | 1987-07-28 | 1994-02-27 | Gist Brocades Nv | SECYMOREVYULK surrogate cells and their use for the expression of polypeptides |
US4853329A (en) * | 1988-06-27 | 1989-08-01 | Miles Inc. | Stabilization of microbial rennet |
JP2974763B2 (ja) | 1989-06-13 | 1999-11-10 | シーエイチアール ハンセン エイエス | キモシンの回収および精製 |
DK47493D0 (da) | 1993-04-27 | 1993-04-27 | Novo Nordisk As | Fremgangsmaade til fremstilling af ost |
JP2739704B2 (ja) * | 1993-08-11 | 1998-04-15 | アサヒビール株式会社 | 飲食品添加用液状パパイン組成物 |
ATE288482T1 (de) * | 1994-05-03 | 2005-02-15 | Hansens Lab | Verfahren zur trennung milchgerinnender enzyme |
JPH1169973A (ja) * | 1997-08-29 | 1999-03-16 | Kao Corp | 酵素の安定化方法 |
JP2002153269A (ja) * | 2000-11-24 | 2002-05-28 | Cosmo Products Kk | プロテアーゼ溶液の安定化方法および皮膚化粧料 |
SE0004808D0 (sv) | 2000-12-20 | 2000-12-20 | Apbiotech Ab | Method for the purification of an enzyme |
US7955829B2 (en) * | 2001-12-19 | 2011-06-07 | Dsm Ip Assets B.V. | Method for the inactivation of amylase in the presence of protease |
EP1365019B1 (en) | 2002-05-21 | 2006-07-26 | DSM IP Assets B.V. | Fermentative production of microbial milk clotting protease |
ATE408681T1 (de) | 2002-05-29 | 2008-10-15 | Dsm Ip Assets Bv | Verfahren zur reinigung einer rhizomucor aspartat-protease |
-
2007
- 2007-04-12 EP EP07728023A patent/EP2004820A1/en not_active Withdrawn
- 2007-04-12 JP JP2009504749A patent/JP5557242B2/ja active Active
- 2007-04-12 CN CNA2007800131928A patent/CN101421397A/zh active Pending
- 2007-04-12 PL PL11156545T patent/PL2333056T3/pl unknown
- 2007-04-12 ES ES11156545.3T patent/ES2478872T3/es active Active
- 2007-04-12 US US12/296,607 patent/US20100009033A1/en not_active Abandoned
- 2007-04-12 EA EA200802140A patent/EA025412B1/ru not_active IP Right Cessation
- 2007-04-12 NZ NZ571699A patent/NZ571699A/en unknown
- 2007-04-12 DK DK11156545.3T patent/DK2333056T3/da active
- 2007-04-12 WO PCT/EP2007/053556 patent/WO2007118838A1/en active Application Filing
- 2007-04-12 EP EP11156545.3A patent/EP2333056B1/en active Active
- 2007-04-12 MX MX2008013182A patent/MX2008013182A/es active IP Right Grant
- 2007-04-12 BR BRPI0709829-4A patent/BRPI0709829A2/pt active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
BRPI0709829A2 (pt) | 2011-07-26 |
EP2004820A1 (en) | 2008-12-24 |
EP2333056B1 (en) | 2014-05-07 |
JP2009533036A (ja) | 2009-09-17 |
WO2007118838A1 (en) | 2007-10-25 |
US20100009033A1 (en) | 2010-01-14 |
DK2333056T3 (da) | 2014-08-04 |
EA025412B1 (ru) | 2016-12-30 |
EA200802140A1 (ru) | 2009-02-27 |
NZ571699A (en) | 2011-07-29 |
EP2333056A1 (en) | 2011-06-15 |
JP5557242B2 (ja) | 2014-07-23 |
MX2008013182A (es) | 2008-10-27 |
PL2333056T3 (pl) | 2014-09-30 |
CN101421397A (zh) | 2009-04-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2478872T3 (es) | Composición líquida que comprende una proteasa aspártica | |
ES2504175T3 (es) | Composición limpiadora de superficies duras ácida y líquida | |
ES2502472T3 (es) | Composición adhesiva para su uso en un inmunosensor | |
ES2525932T3 (es) | Derivados de dihidrotetrabenazina radiomarcados y su uso como agentes de imagenología | |
ES2665917T3 (es) | Endoxifeno para su uso en el tratamiento del cáncer | |
AR109135A2 (es) | Forma sólida de una sal hidratada de tartrato de un compuesto de pirrolidina inhibidor de dpp-iv | |
ES2564807T3 (es) | Proceso para preparación de rosuvastatina de calcio amorfa pura | |
ES2629749T3 (es) | Inmunidad tumoral | |
TW200710133A (en) | Cellulose ester film, polarizing plate and liquid crystal display | |
DE502007004588D1 (de) | Neue salze des wirkstoffs rasagilin | |
AR108955A2 (es) | Suspensión oftálmica acuosa de rebamipida cristalina | |
ES2477867T3 (es) | Medio de almacenamiento para células | |
ES2546198T3 (es) | Tratamiento contra la glomerulonefritis | |
ES2527639T3 (es) | Composición de limpieza antimicrobiana con bajo contenido de alcohol | |
ES2544336T3 (es) | Composición de revestimiento fotoestable antimicrobiana | |
PE20090211A1 (es) | Inhibidores de las iap | |
ES2531155T3 (es) | Cristalización de anticuerpos anti-VEGF | |
ES2488407T3 (es) | Preparación farmacéutica que contiene lipasa de origen bacteriano | |
TW200736367A (en) | Luminous substance and light source with such luminous substance as well as manufacturing method of the luminous substance | |
BRPI0520527A2 (pt) | seleção de coeficiente para sinalização com marca d' água em vìdeo | |
EA201071409A1 (ru) | Новые соли (4-{[(5-{[(3-хлорфенил)метил]окси}-2-метилфенил)карбонил]амино}-3-метилфенил)уксусной кислоты | |
DOP2011000329A (es) | Preparacion de solido | |
GT200500377A (es) | Compuesto quimico y su uso | |
JP2005295818A5 (es) | ||
PE20070548A1 (es) | Formas cristalinas de la sal de di-sodio del acido n-(5-clorosaliciloil)-8-aminocaprilico |