ES2476240T1 - Agente antibacteriano para tratar enfermedades infecciosas de origen bacteriano - Google Patents

Agente antibacteriano para tratar enfermedades infecciosas de origen bacteriano Download PDF

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Publication number
ES2476240T1
ES2476240T1 ES11853027.8T ES11853027T ES2476240T1 ES 2476240 T1 ES2476240 T1 ES 2476240T1 ES 11853027 T ES11853027 T ES 11853027T ES 2476240 T1 ES2476240 T1 ES 2476240T1
Authority
ES
Spain
Prior art keywords
antibacterial agent
infectious diseases
bacterial origin
treat infectious
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES11853027.8T
Other languages
English (en)
Other versions
ES2476240T3 (es
Inventor
Alexandr Ivanovich ILIN
Murat Esengalievich KULMANOV
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RESPUB G PREDPR NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV KOMITETA PROMY MINISTER I NOVYH TEHNOL
RESPUBLIKANSKOE GOSUDARSTVENNOE PREDPRIYATIE "NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV" KOMITETA PROMYSHLENNOSTI MINISTER I NOVYH TEHNOLOGIJ RESPUBLIKI KAZAKHSTAN
Original Assignee
RESPUB G PREDPR NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV KOMITETA PROMY MINISTER I NOVYH TEHNOL
RESPUBLIKANSKOE GOSUDARSTVENNOE PREDPRIYATIE "NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV" KOMITETA PROMYSHLENNOSTI MINISTER I NOVYH TEHNOLOGIJ RESPUBLIKI KAZAKHSTAN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by RESPUB G PREDPR NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV KOMITETA PROMY MINISTER I NOVYH TEHNOL, RESPUBLIKANSKOE GOSUDARSTVENNOE PREDPRIYATIE "NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV" KOMITETA PROMYSHLENNOSTI MINISTER I NOVYH TEHNOLOGIJ RESPUBLIKI KAZAKHSTAN filed Critical RESPUB G PREDPR NAUCHNYJ CENTR PROTIVOINFEKCIONNYH PREPARATOV KOMITETA PROMY MINISTER I NOVYH TEHNOL
Publication of ES2476240T1 publication Critical patent/ES2476240T1/es
Application granted granted Critical
Publication of ES2476240T3 publication Critical patent/ES2476240T3/es
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Agente antibacteriano para el tratamiento de enfermedades infecciosas bacterianas incluidas las infecciones hospitalarias y la tuberculosis resistente a los fármacos, que se representa como un complejo nanoestructurado iónico formado por proteínas y / o polipéptidos, hidratos de carbono, sales de metales alcalinos y alcalino-térreos y yodo intercalado entre ellos, caracterizado porque las proteínas y / o los polipéptidos del complejo nanoestructurado iónico contienen al menos un aminoácido con grupos funcionales donadores de electrones situado en el extremo de la cadena .

Claims (1)

  1. imagen1
ES11853027.8T 2010-12-30 2011-12-09 Agente antibacteriano para el tratamiento de enfermedades infecciosas de origen bacteriano Active ES2476240T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KZ20101816 2010-12-30
KZ20101816 2010-12-30
PCT/KZ2011/000019 WO2012091534A1 (ru) 2010-12-30 2011-12-09 Антибактериальный агент для лечения инфекционных заболеваний бактериальной природы

Publications (2)

Publication Number Publication Date
ES2476240T1 true ES2476240T1 (es) 2014-07-14
ES2476240T3 ES2476240T3 (es) 2018-03-06

Family

ID=46383344

Family Applications (1)

Application Number Title Priority Date Filing Date
ES11853027.8T Active ES2476240T3 (es) 2010-12-30 2011-12-09 Agente antibacteriano para el tratamiento de enfermedades infecciosas de origen bacteriano

Country Status (19)

Country Link
US (3) US10149890B2 (es)
EP (1) EP2722053B1 (es)
JP (1) JP6041811B2 (es)
CN (1) CN103442728B (es)
CY (1) CY20142200001T2 (es)
DE (1) DE11853027T1 (es)
DK (1) DK2722053T3 (es)
EA (1) EA024595B1 (es)
ES (1) ES2476240T3 (es)
HR (1) HRP20180075T1 (es)
HU (1) HUE035149T2 (es)
IL (1) IL227132B (es)
LT (1) LT2722053T (es)
NO (1) NO2722053T3 (es)
PL (1) PL2722053T3 (es)
RS (1) RS56687B1 (es)
SG (1) SG192563A1 (es)
SI (1) SI2722053T1 (es)
WO (1) WO2012091534A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022126127A1 (en) * 2020-12-12 2022-06-16 Iocure, Inc. Iodine delivery compounds
CN114634762A (zh) * 2022-03-17 2022-06-17 东莞市人民医院 金属离子介导的蛋白质涂层、其制备方法及其应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1066979A (zh) * 1991-05-20 1992-12-16 中国人民解放军军事医学科学院微生物流行病研究所 烧伤创面抗菌制剂的制备方法
US6777003B1 (en) 1995-06-07 2004-08-17 Cognis Corporation Iodine complex of alkyl polyglycosides
KZ6730B (es) 1996-01-26 1998-11-16
DE29923848U1 (de) 1998-05-27 2001-04-12 Euroceltique S.A., Luxemburg/Luxembourg Präparate zur Anwendung von entzündungshemmenden, insbesondere antiseptischen Wirkstoffen und/oder die Wundheilung fördernden Wirkstoffen in den oberen Atemwegen und/oder dem Ohr
CZ295765B6 (cs) 1998-07-29 2005-10-12 Apa - Praha, S.R.O. Léčebný přípravek s virucidním účinkem
RU2157405C2 (ru) 1998-12-11 2000-10-10 Тверская государственная медицинская академия Способ получения иммобилизованных ферментов с помощью реакции комплексообразования с молекулярным йодом и йодидом калия
WO2001078751A1 (en) * 2000-04-17 2001-10-25 'armenicum+' Jsc Antiviral and antibacterial pharmaceutical preparation 'armenicum' and its use for treatment of infectious diseases
AM949A2 (es) 2000-04-17 2001-06-10 Armenicum & Jsc
CN1162399C (zh) * 2001-04-28 2004-08-18 曾雄飞 氨基酸碘络合物
KZ15116A (es) * 2002-11-08 2004-12-15
WO2004096180A1 (en) * 2003-04-29 2004-11-11 Baxter International Inc. Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
RU2411960C2 (ru) * 2009-05-04 2011-02-20 Некоммерческое партнерство по научной и инновационной деятельности "Томский атомный центр" Раневая повязка

Also Published As

Publication number Publication date
IL227132B (en) 2019-01-31
CN103442728A (zh) 2013-12-11
LT2722053T (lt) 2017-12-11
HRP20180075T1 (hr) 2018-02-23
NO2722053T3 (es) 2018-03-24
SI2722053T1 (en) 2018-02-28
US10251939B2 (en) 2019-04-09
DE11853027T1 (de) 2014-09-11
PL2722053T3 (pl) 2018-04-30
US20190134157A1 (en) 2019-05-09
EP2722053A4 (en) 2014-09-03
EA024595B1 (ru) 2016-10-31
CN103442728B (zh) 2017-04-12
JP6041811B2 (ja) 2016-12-14
ES2476240T3 (es) 2018-03-06
CY20142200001T2 (el) 2016-06-22
WO2012091534A1 (ru) 2012-07-05
DK2722053T3 (da) 2017-11-20
US20150374837A1 (en) 2015-12-31
US10149890B2 (en) 2018-12-11
RS56687B1 (sr) 2018-03-30
JP2014502616A (ja) 2014-02-03
EP2722053B1 (en) 2017-10-25
HUE035149T2 (en) 2018-05-02
SG192563A1 (en) 2013-09-30
US20140010782A1 (en) 2014-01-09
EA201290002A1 (ru) 2012-09-28
EP2722053A1 (en) 2014-04-23

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