ES2463678T3 - Composición que comprende echovirus EV1 y su uso - Google Patents
Composición que comprende echovirus EV1 y su uso Download PDFInfo
- Publication number
- ES2463678T3 ES2463678T3 ES03779569.7T ES03779569T ES2463678T3 ES 2463678 T3 ES2463678 T3 ES 2463678T3 ES 03779569 T ES03779569 T ES 03779569T ES 2463678 T3 ES2463678 T3 ES 2463678T3
- Authority
- ES
- Spain
- Prior art keywords
- cancer
- cells
- virus
- treatment
- echovirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/768—Oncolytic viruses not provided for in groups A61K35/761 - A61K35/766
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32311—Enterovirus
- C12N2770/32332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002953436 | 2002-12-18 | ||
| AU2002953436A AU2002953436A0 (en) | 2002-12-18 | 2002-12-18 | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
| PCT/AU2003/001688 WO2004054613A1 (en) | 2002-12-18 | 2003-12-18 | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2463678T3 true ES2463678T3 (es) | 2014-05-28 |
Family
ID=30004521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03779569.7T Expired - Lifetime ES2463678T3 (es) | 2002-12-18 | 2003-12-18 | Composición que comprende echovirus EV1 y su uso |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7485292B2 (https=) |
| EP (1) | EP1581257B1 (https=) |
| JP (2) | JP2006517189A (https=) |
| KR (1) | KR101171295B1 (https=) |
| CN (2) | CN102166228B (https=) |
| AU (1) | AU2002953436A0 (https=) |
| CA (1) | CA2510227C (https=) |
| ES (1) | ES2463678T3 (https=) |
| NZ (1) | NZ541230A (https=) |
| WO (1) | WO2004054613A1 (https=) |
| ZA (1) | ZA200505389B (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPQ425699A0 (en) | 1999-11-25 | 1999-12-23 | University Of Newcastle Research Associates Limited, The | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
| AU2002953436A0 (en) * | 2002-12-18 | 2003-01-09 | The University Of Newcastle Research Associates Limited | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
| CA2577692C (en) | 2004-08-20 | 2014-05-06 | Viralytics Limited | Methods and compositions for treatment of hematologic cancers |
| WO2006074526A1 (en) * | 2005-01-17 | 2006-07-20 | Viralytics Limited | Method and composition for treatment of neoplasms |
| EP2851078B1 (en) * | 2012-04-19 | 2017-06-07 | Kyushu University, National University Corporation | Pharmaceutical composition |
| EP2826856B9 (en) | 2013-07-16 | 2016-05-04 | Sia Latima | Genetically stable oncolytic RNA virus, method of manufacturing and use thereof |
| RU2682762C2 (ru) * | 2013-11-27 | 2019-03-21 | Общество С Ограниченной Ответственностью "Панацела Лабс" | Улучшенный вектор, экспрессирующий toll-подобный рецептор и агонист, и применение в терапии рака |
| WO2015127501A1 (en) | 2014-02-27 | 2015-09-03 | Viralytics Limited | Combination method for treatment of cancer |
| CN103981152B (zh) * | 2014-04-16 | 2015-01-21 | 武汉博威德生物技术有限公司 | 一种柯萨奇病毒及其制备抗肿瘤药物之应用 |
| EP4023233B1 (en) | 2016-09-27 | 2026-01-07 | Sator Therapeutics LLC | Optimized oncolytic viruses and uses thereof |
| EP3610870A4 (en) * | 2017-03-31 | 2020-12-09 | Ogata, Hisanobu | METHOD OF EXPANSION OF AN ONCOLYTIC VIRUS AND ANTI-TUMOR AGENT |
| CN109419818B (zh) * | 2017-08-24 | 2021-08-10 | 厦门大学 | 一种用于治疗肿瘤的埃可病毒 |
| CN107669707A (zh) * | 2017-11-16 | 2018-02-09 | 邹罡 | 埃可病毒作为溶瘤病毒在抗肿瘤中的应用 |
| EP3880812A4 (en) * | 2018-11-13 | 2022-09-07 | Oncorus, Inc. | ENCAPSULATED POLYNUCLEOTIDES AND METHODS OF USE |
| CA3207359A1 (en) | 2021-02-05 | 2022-08-11 | Cecile Chartier-Courtaud | Adjuvant therapy for cancer |
Family Cites Families (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS54113421A (en) * | 1978-02-24 | 1979-09-05 | Fumiaki Taguchi | Large scale cultivation of virus |
| US5585254A (en) * | 1987-08-21 | 1996-12-17 | University Of Colorado Foundation, Inc. | Autonomous parvovirus gene delivery vehicles and expression vectors |
| JPH04504361A (ja) | 1989-04-05 | 1992-08-06 | ノバセル コーポレイション | 感染性標的化複製―欠陥ビリオン |
| CA2051289C (en) | 1990-09-14 | 2002-11-26 | Robert L. Martuza | Viral mediated destruction of neoplastic cells |
| US5173414A (en) * | 1990-10-30 | 1992-12-22 | Applied Immune Sciences, Inc. | Production of recombinant adeno-associated virus vectors |
| WO1993000442A1 (en) * | 1991-06-24 | 1993-01-07 | The Research Foundation Of State University Of New York | De novo cell-free synthesis of picornavirus |
| JPH06509578A (ja) * | 1991-07-26 | 1994-10-27 | ユニバーシティ・オブ・ロチェスター | 悪性細胞利用による癌治療法 |
| US5529774A (en) * | 1991-08-13 | 1996-06-25 | The Regents Of The University Of California | In vivo transfer of the HSV-TK gene implanted retroviral producer cells |
| SE503225C2 (sv) | 1991-10-30 | 1996-04-22 | Leif Lindholm Konsult Ab | Virus-antikroppskomplex för införing av virus i mammalieceller |
| US5846945A (en) * | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| ATE199568T1 (de) | 1993-02-16 | 2001-03-15 | Onyx Pharma Inc | Cytopatische viren zur therapie und prophylaxe der neoplasie |
| EP2009119A1 (en) | 1993-04-30 | 2008-12-31 | Wellstat Biologics Corporation | Compositions for treating cancer using viruses |
| US5585096A (en) | 1994-06-23 | 1996-12-17 | Georgetown University | Replication-competent herpes simplex virus mediates destruction of neoplastic cells |
| US5728379A (en) | 1994-06-23 | 1998-03-17 | Georgetown University | Tumor- or cell-specific herpes simplex virus replication |
| US5688773A (en) * | 1994-08-17 | 1997-11-18 | The General Hospital Corporation | Method of selectively destroying neoplastic cells |
| US6071742A (en) | 1997-03-05 | 2000-06-06 | Board Of Regents Of The University Of Nebraska | Coxsackie virus as a vector for delivery of anti-inflammatory cytokines |
| US6136307A (en) | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| IL135507A0 (en) | 1997-10-09 | 2001-05-20 | Pro Virus Inc | Treatment of neoplasms with viruses |
| CA2323067A1 (en) | 1998-03-12 | 1999-09-16 | The Trustees Of The University Of Pennsylvania | Producer cells for replication selective viruses in the treatment of malignancy |
| US6060316A (en) * | 1998-06-09 | 2000-05-09 | President And Fellows Of Harvard College | Methods of targeting of viral entry |
| US6264940B1 (en) | 1998-08-05 | 2001-07-24 | The Research Foundation Of State University Of New York | Recombinant poliovirus for the treatment of cancer |
| DE60039730D1 (de) | 1999-02-05 | 2008-09-11 | Arch Dev Corp | Genetisch manipulierte Herpesviren zur Behandlung von Tumoren |
| AU2005201079C1 (en) | 1999-04-15 | 2008-11-06 | Wellstat Biologics Corporation | Treatment of neoplasms with viruses |
| JP2003530301A (ja) | 1999-04-15 | 2003-10-14 | ウェルスタット バイオロジクス コーポレイション | ウイルスを用いた新生物の処置 |
| EP1067188A1 (en) | 1999-07-08 | 2001-01-10 | Introgene B.V. | Infection with chimaeric adenoviruses of cells negative for the adenovirus serotype 5 Coxsacki adenovirus receptor (CAR) |
| DE19939095A1 (de) | 1999-08-18 | 2001-02-22 | Univ Eberhard Karls | Von Coxsackieviren abgeleitetes Vektorsystem für Gentransfer |
| NZ517573A (en) | 1999-09-17 | 2004-02-27 | Pro Virus Inc | Sequences of the oncolytic virus strain vesicular stromatitis virus (VSV) |
| EP1955703A1 (en) | 1999-11-12 | 2008-08-13 | Oncolytics Biotech Inc. | Viruses for the treatment of cellular proliferative disorders |
| ES2288488T3 (es) | 1999-11-15 | 2008-01-16 | Onyx Pharmaceuticals, Inc. | Adenovirus oncoliticos. |
| AU2004202292B2 (en) | 1999-11-25 | 2007-06-14 | Viralytics Limited | Method of Treating a Malignancy in a Subject |
| AUPQ425699A0 (en) | 1999-11-25 | 1999-12-23 | University Of Newcastle Research Associates Limited, The | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
| AU770517B2 (en) | 1999-11-25 | 2004-02-26 | Viralytics Limited | A method of treating a malignancy in a subject and a pharmaceutical composition for use in same |
| DE60115600T2 (de) | 2000-01-21 | 2006-07-20 | Biovex Ltd. | Virusstämme für die onkolytische behandlung von krebs |
| CA2341356C (en) | 2000-04-14 | 2011-10-11 | Transgene S.A. | Poxvirus with targeted infection specificity |
| US7306902B2 (en) | 2002-06-28 | 2007-12-11 | Oncolyties Biotech Inc. | Oncolytic viruses as phenotyping agents for neoplasms |
| EP1286678A2 (en) | 2000-06-01 | 2003-03-05 | Sloan-Kettering Institute For Cancer Research | Combination of a mutant herpes virus and a chemotherapeutic agent for the treatment of cancer |
| JP2004519431A (ja) | 2000-12-01 | 2004-07-02 | ユニバーシティ・オブ・オタワ | 腫瘍溶解性ウイルス |
| AU2002318104A1 (en) * | 2001-01-05 | 2002-11-25 | Corixa Corporation | Microparticles and methods for delivery of recombinant viral vaccines |
| WO2002087625A1 (en) | 2001-05-02 | 2002-11-07 | Ramot At Tel-Aviv University Ltd. | Composite oncolytic herpes virus vectors |
| US7264814B2 (en) | 2001-05-09 | 2007-09-04 | M's Science Corporation | Composition and method for treating cancer using herpes virus |
| EP1385466B1 (en) | 2001-05-11 | 2011-03-09 | Wellstat Biologics Corporation | Oncolytic virus therapy |
| CA2352439A1 (en) | 2001-07-17 | 2003-01-17 | Patrick W. K. Lee | Engineering oncolytic viruses |
| EP1409653A4 (en) | 2001-07-23 | 2006-05-03 | Onyx Pharma Inc | IN HUMAN TARGET CANCELLS SELECTIVELY REPLICATING VIRUS MUTANTS |
| AU2003216502B2 (en) | 2002-03-01 | 2008-04-10 | Sloan-Kettering Institute For Cancer Research | Prevention of recurrence and metastasis of cancer |
| AU2003258060B2 (en) | 2002-03-27 | 2007-07-12 | Baylor College Of Medicine | Potent oncolytic herpes simplex virus for cancer therapy |
| EP1499332A4 (en) | 2002-04-29 | 2006-12-06 | Hadasit Med Res Service | COMPOSITIONS AND METHODS FOR TREATING CANCER WITH A VIRAL ONCOLYTIC AGENT |
| DE03722131T1 (de) | 2002-05-09 | 2005-09-15 | Oncolytics Biotech, Inc., Calgary | Methode zur schmerzbekämpfung mit onkolytischen viren |
| AU2002953436A0 (en) | 2002-12-18 | 2003-01-09 | The University Of Newcastle Research Associates Limited | A method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis |
| WO2005002607A2 (en) | 2003-07-07 | 2005-01-13 | Oncolytics Biotech Inc. | Oncolytic reoviruses for the treatment of neoplasms having activated pp2a or rac |
| US20070036758A1 (en) | 2003-07-08 | 2007-02-15 | Bertram Jacobs | Mutants of vaccinia virus as oncolytic agents |
| WO2005030139A2 (en) | 2003-09-26 | 2005-04-07 | Novartis Ag | Seneca valley virus based compositions and methods for treating disease |
| AU2005221725B2 (en) | 2004-03-11 | 2010-06-24 | Viralytics Limited | Modified oncolytic viruses |
| WO2005107474A2 (en) | 2004-04-30 | 2005-11-17 | Introgen Therapeutics, Inc. | Oncolytic adenovirus armed with therapeutic genes |
| US7731952B2 (en) | 2004-06-24 | 2010-06-08 | New York University | Avirulent oncolytic herpes simplex virus strains engineered to counter the innate host response |
| US8080240B2 (en) | 2004-10-21 | 2011-12-20 | The Penn State Research Foundation | Parvovirus methods and compositions for killing neoplastic cells |
-
2002
- 2002-12-18 AU AU2002953436A patent/AU2002953436A0/en not_active Abandoned
-
2003
- 2003-12-18 US US10/539,219 patent/US7485292B2/en not_active Expired - Lifetime
- 2003-12-18 EP EP03779569.7A patent/EP1581257B1/en not_active Expired - Lifetime
- 2003-12-18 ZA ZA200505389A patent/ZA200505389B/en unknown
- 2003-12-18 WO PCT/AU2003/001688 patent/WO2004054613A1/en not_active Ceased
- 2003-12-18 KR KR1020057011510A patent/KR101171295B1/ko not_active Expired - Fee Related
- 2003-12-18 ES ES03779569.7T patent/ES2463678T3/es not_active Expired - Lifetime
- 2003-12-18 CA CA2510227A patent/CA2510227C/en not_active Expired - Fee Related
- 2003-12-18 CN CN201110091011.1A patent/CN102166228B/zh not_active Expired - Fee Related
- 2003-12-18 NZ NZ541230A patent/NZ541230A/en not_active IP Right Cessation
- 2003-12-18 JP JP2004559490A patent/JP2006517189A/ja active Pending
- 2003-12-18 CN CN2003801098083A patent/CN1784242B/zh not_active Expired - Fee Related
-
2009
- 2009-02-03 US US12/365,120 patent/US20100062020A1/en not_active Abandoned
-
2011
- 2011-07-08 JP JP2011151340A patent/JP2012046489A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ541230A (en) | 2008-04-30 |
| CN1784242A (zh) | 2006-06-07 |
| CA2510227A1 (en) | 2004-07-01 |
| CA2510227C (en) | 2015-03-31 |
| US20100062020A1 (en) | 2010-03-11 |
| CN102166228A (zh) | 2011-08-31 |
| KR20050115859A (ko) | 2005-12-08 |
| ZA200505389B (en) | 2006-09-27 |
| US20060134778A1 (en) | 2006-06-22 |
| EP1581257A1 (en) | 2005-10-05 |
| AU2002953436A0 (en) | 2003-01-09 |
| CN1784242B (zh) | 2011-06-08 |
| JP2012046489A (ja) | 2012-03-08 |
| HK1157657A1 (en) | 2012-07-06 |
| US7485292B2 (en) | 2009-02-03 |
| EP1581257A4 (en) | 2007-10-17 |
| WO2004054613A1 (en) | 2004-07-01 |
| JP2006517189A (ja) | 2006-07-20 |
| EP1581257B1 (en) | 2014-04-30 |
| CN102166228B (zh) | 2014-02-19 |
| KR101171295B1 (ko) | 2012-08-07 |
| HK1082194A1 (en) | 2006-06-02 |
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