ES2463016T3 - Conjugados y composiciones para inmunoterapia y tratamiento anti-tumoral - Google Patents
Conjugados y composiciones para inmunoterapia y tratamiento anti-tumoral Download PDFInfo
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- ES2463016T3 ES2463016T3 ES10814739.8T ES10814739T ES2463016T3 ES 2463016 T3 ES2463016 T3 ES 2463016T3 ES 10814739 T ES10814739 T ES 10814739T ES 2463016 T3 ES2463016 T3 ES 2463016T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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Landscapes
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- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| PCT/ES2010/070818 WO2011070214A2 (es) | 2009-12-11 | 2010-12-10 | Conjugados y composiciones para inmunoterapia y tratamiento anti-tumoral |
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| WO2015089217A2 (en) | 2013-12-10 | 2015-06-18 | Bionz, Llc | Methods of developing selective peptide antagonists |
| ES2778053T3 (es) | 2011-01-18 | 2020-08-07 | Bioniz Llc | Composiciones para modular la actividad de la citocina gamma-c |
| EP2537933A1 (en) * | 2011-06-24 | 2012-12-26 | Institut National de la Santé et de la Recherche Médicale (INSERM) | An IL-15 and IL-15Ralpha sushi domain based immunocytokines |
| KR102539359B1 (ko) * | 2013-04-19 | 2023-06-02 | 싸이튠 파마 | 감소된 혈관 누출 증후군에 대한 사이토카인 유도체 치료 |
| CA2954741C (en) * | 2013-10-13 | 2023-10-03 | Nova Southeastern University | Identification of a natural killer cell population as potential therapeutic targets for gulf war illness and myalgic encephalomyelitis/chronic fatigue syndrome |
| EP3094351B9 (en) | 2014-01-15 | 2022-04-13 | Kadmon Corporation, LLC | Immunomodulatory agents |
| EP2915569A1 (en) | 2014-03-03 | 2015-09-09 | Cytune Pharma | IL-15/IL-15Ralpha based conjugates purification method |
| WO2015164107A1 (en) | 2014-04-23 | 2015-10-29 | Emory University | Compositions of gm-csf and interleukin fusions for immune modulation and uses related thereto |
| US12577323B2 (en) | 2015-06-10 | 2026-03-17 | Emory University | Compositions and conjugates comprising an interleukin and polypeptides that specifically bind TGF-beta |
| CN106317225A (zh) * | 2015-06-28 | 2017-01-11 | 复旦大学 | 具有靶向性长效白细胞介素22融合蛋白及其制备方法和用途 |
| EP3359556B1 (en) | 2015-10-09 | 2021-05-26 | Bioniz, LLC | Modulating gamma - c -cytokine activity |
| EP3443001B1 (en) | 2016-04-11 | 2025-04-30 | Obsidian Therapeutics, Inc. | REGULATED BIOCIRCUIT SYSTEMS |
| US11472856B2 (en) | 2016-06-13 | 2022-10-18 | Torque Therapeutics, Inc. | Methods and compositions for promoting immune cell function |
| US11629340B2 (en) | 2017-03-03 | 2023-04-18 | Obsidian Therapeutics, Inc. | DHFR tunable protein regulation |
| KR20240142577A (ko) | 2017-04-07 | 2024-09-30 | 바이오니즈 테라퓨틱스, 아이엔씨. | 감마-c-사이토카인 활성의 안정한 조절자 |
| US11344578B2 (en) | 2017-04-19 | 2022-05-31 | Board Of Regents, The University Of Texas System | Immune cells expressing engineered antigen receptors |
| KR20210032924A (ko) | 2017-09-05 | 2021-03-25 | 토크 테라퓨틱스, 인코포레이티드 | 치료용 단백질 조성물 및 그의 제조 및 사용 방법 |
| CA3086040A1 (en) | 2017-12-19 | 2019-06-27 | Blaze Bioscience, Inc. | Tumor homing and cell penetrating peptide-immuno-oncology agent complexes and methods of use thereof |
| WO2019165121A1 (en) | 2018-02-21 | 2019-08-29 | Board Of Regents, The University Of Texas System | Methods for activation and expansion of natural killer cells and uses therof |
| JP2022530677A (ja) | 2019-05-03 | 2022-06-30 | バイオニズ リミテッド ライアビリティー カンパニー | 脱毛症および脱毛症関連障害の治療ための、γｃサイトカインのシグナル伝達の効果の調節 |
| WO2023064469A1 (en) * | 2021-10-13 | 2023-04-20 | Modernatx, Inc. | Compositions of mrna-encoded il15 fusion proteins and methods of use thereof |
| EP4565251A1 (en) * | 2022-08-07 | 2025-06-11 | Protean Bio, Inc. | Peptides for beta-cell survival and insulin production |
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| AU6408586A (en) * | 1985-10-03 | 1987-04-24 | Biotechnology Research Partners Limited | Novel lipoprotein-based drug-delivery systems |
| US4999403A (en) | 1988-10-28 | 1991-03-12 | Exxon Chemical Patents Inc. | Graft polymers of functionalized ethylene-alpha-olefin copolymer with polypropylene, methods of preparation, and use in polypropylene compositions |
| US5747024A (en) | 1993-03-08 | 1998-05-05 | Immunex Corporation | Vaccine adjuvant comprising interleukin-15 |
| EP0814838B1 (en) | 1995-03-08 | 2003-05-14 | The Scripps Research Institute | Antigen presenting system and activation of t-cells |
| US6787154B2 (en) | 1998-10-20 | 2004-09-07 | Salvatore Albani | Artificial antigen presenting cells |
| JP4344136B2 (ja) | 2000-11-10 | 2009-10-14 | エフ・ホフマン−ラ・ロシュ・リミテッド | アポリポタンパク質類似体 |
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| US20060257361A1 (en) | 2005-04-12 | 2006-11-16 | Government Of The Us, As Represented By The Secretary, Department Of Health And Human Services | Novel form of interleukin-15, Fc-IL-15, and methods of use |
| US8242081B2 (en) | 2005-12-06 | 2012-08-14 | Centre National De La Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| EP2049560B1 (en) | 2006-07-13 | 2013-05-15 | Novozymes Biopharma DK A/S | Process for preparing particles of proteinaceous material |
| KR100817024B1 (ko) | 2006-11-09 | 2008-03-26 | 재단법인 목암생명공학연구소 | 핵산 또는 약물을 간에 특이적으로 전달하는 복합체 및이를 포함하는 약학적 조성물 |
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- 2010-12-10 ES ES10814739.8T patent/ES2463016T3/es active Active
- 2010-12-10 CN CN201080061939.9A patent/CN102753574B/zh not_active Expired - Fee Related
- 2010-12-10 BR BR112012013868A patent/BR112012013868A8/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2511294A2 (en) | 2012-10-17 |
| CA2783876C (en) | 2018-04-03 |
| BR112012013868A8 (pt) | 2017-12-26 |
| US20120244118A1 (en) | 2012-09-27 |
| EP2511294B1 (en) | 2014-02-26 |
| JP5784626B2 (ja) | 2015-09-24 |
| CN102753574A (zh) | 2012-10-24 |
| WO2011070214A2 (es) | 2011-06-16 |
| RU2012129208A (ru) | 2014-01-20 |
| MX2012006691A (es) | 2013-02-26 |
| AU2010329805A1 (en) | 2012-07-05 |
| WO2011070214A3 (es) | 2011-08-04 |
| US8771664B2 (en) | 2014-07-08 |
| CN102753574B (zh) | 2015-05-20 |
| WO2011070214A8 (es) | 2011-09-29 |
| AU2010329805B2 (en) | 2016-07-14 |
| CA2783876A1 (en) | 2011-06-16 |
| BR112012013868A2 (pt) | 2017-01-10 |
| RU2597989C2 (ru) | 2016-09-20 |
| JP2013513377A (ja) | 2013-04-22 |
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