ES2451620T3 - Composiciones y métodos destinados a tratar o prevenir la infección neumocócica - Google Patents
Composiciones y métodos destinados a tratar o prevenir la infección neumocócica Download PDFInfo
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- ES2451620T3 ES2451620T3 ES03768757.1T ES03768757T ES2451620T3 ES 2451620 T3 ES2451620 T3 ES 2451620T3 ES 03768757 T ES03768757 T ES 03768757T ES 2451620 T3 ES2451620 T3 ES 2451620T3
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
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- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
Landscapes
- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
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| US42449702P | 2002-11-07 | 2002-11-07 | |
| US424497P | 2002-11-07 | ||
| PCT/US2003/035529 WO2004043376A2 (en) | 2002-11-07 | 2003-11-06 | Compositions and methods for treating or preventing pneumococcal infection |
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| ES2451620T3 true ES2451620T3 (es) | 2014-03-28 |
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| GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| AU2009208403A1 (en) * | 2008-02-01 | 2009-08-06 | Newcastle Innovation Limited | Vaccine compositions |
| RU2555757C2 (ru) | 2009-03-24 | 2015-07-10 | Новартис Аг | Комбинации менингококкового фактор н-связывающего белка и пневмококковых сахаридных конъюгатов |
| BR112012008338A2 (pt) | 2009-09-10 | 2019-09-24 | Novartis Ag | combinação de vacinas contra doenças do trato respiratório. |
| GB201003922D0 (en) | 2010-03-09 | 2010-04-21 | Glaxosmithkline Biolog Sa | Conjugation process |
| US20130039947A1 (en) | 2010-03-12 | 2013-02-14 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
| WO2012072769A1 (en) | 2010-12-01 | 2012-06-07 | Novartis Ag | Pneumococcal rrgb epitopes and clade combinations |
| MX383544B (es) * | 2011-04-21 | 2025-03-14 | Univ Rockefeller | Lisinas de bacteriofago de streptococcus para la deteccion y tratamiento de bacterias gram positivas |
| CA2834834A1 (en) | 2011-05-17 | 2012-11-22 | Glaxosmithkline Biologicals S.A. | Vaccine against streptococcus pneumoniae |
| CN104114695B (zh) * | 2011-10-05 | 2018-04-17 | 洛克菲勒大学 | 二聚噬菌体溶素 |
| US20150132339A1 (en) | 2012-03-07 | 2015-05-14 | Novartis Ag | Adjuvanted formulations of streptococcus pneumoniae antigens |
| WO2014124228A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| EP3220937B1 (en) | 2014-11-21 | 2024-09-04 | The Board of Regents of the University of Oklahoma | Pneumolysin mutants and methods of use thereof |
| GB201610599D0 (en) * | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US11951165B2 (en) | 2016-12-30 | 2024-04-09 | Vaxcyte, Inc. | Conjugated vaccine carrier proteins |
| KR20190103256A (ko) | 2016-12-30 | 2019-09-04 | 수트로박스, 인코포레이티드 | 비자연 아미노산을 갖는 폴리펩타이드-항원 접합체 |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| JP7438102B2 (ja) | 2017-09-07 | 2024-02-26 | メルク・シャープ・アンド・ドーム・エルエルシー | 肺炎球菌多糖体および免疫原性多糖体－キャリアタンパク質コンジュゲートでのその使用 |
| BR112021004193A2 (pt) | 2018-09-12 | 2021-05-25 | Affinivax, Inc. | vacinas pneumocócicas multivalentes |
| CA3231684A1 (en) | 2021-09-09 | 2023-03-16 | Affinivax, Inc. | Multivalent pneumococcal vaccines |
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| DE68929323T2 (de) * | 1988-12-16 | 2002-04-18 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezondheid En Cultuur | Pneumolysin-mutanten und pneumokokken-impfstoffe daraus |
| WO1995016711A1 (es) * | 1993-12-17 | 1995-06-22 | Universidad De Oviedo | Anticuerpos contra la neumolisina y sus aplicaciones |
| US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| WO1999003884A2 (en) * | 1997-07-21 | 1999-01-28 | North American Vaccine, Inc. | Modified immunogenic pneumolysin, compositions and their use as vaccines |
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| WO2000006737A2 (en) * | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | Streptococcus pneumoniae proteins and nucleic acid molecules |
| MXPA01005615A (es) * | 1998-12-04 | 2004-08-19 | Univ Manitoba | Procedimiento de inmunizacion en dos pasos para proteger contra infeccion por chlamydia. |
| CA2360347C (en) * | 1998-12-31 | 2013-05-07 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| WO2001044477A1 (en) * | 1999-12-17 | 2001-06-21 | American Cyanamid Company | Method of enhancing immune responses to herpes simplex virus vaccine |
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| US7585669B2 (en) | 2009-09-08 |
| JP2010057501A (ja) | 2010-03-18 |
| TW200418502A (en) | 2004-10-01 |
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| CA2504938C (en) | 2011-10-11 |
| US20040213803A1 (en) | 2004-10-28 |
| EP1558280A2 (en) | 2005-08-03 |
| US20080199952A1 (en) | 2008-08-21 |
| CA2504938A1 (en) | 2004-05-27 |
| JP2012139221A (ja) | 2012-07-26 |
| CN1711105A (zh) | 2005-12-21 |
| HK1074005A1 (en) | 2005-10-28 |
| KR20050086427A (ko) | 2005-08-30 |
| EP1558280B1 (en) | 2014-01-08 |
| WO2004043376A3 (en) | 2004-10-14 |
| TWI315986B (en) | 2009-10-21 |
| WO2004043376A2 (en) | 2004-05-27 |
| CN100443116C (zh) | 2008-12-17 |
| EP1558280A4 (en) | 2007-08-29 |
| JP2006506989A (ja) | 2006-03-02 |
| AU2003291365A1 (en) | 2004-06-03 |
| AU2003291365B2 (en) | 2009-06-11 |
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