ES2436744T3 - Sistema para derivar un eluyente de cromatografía de líquidos - Google Patents

Sistema para derivar un eluyente de cromatografía de líquidos Download PDF

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Publication number
ES2436744T3
ES2436744T3 ES12175163.0T ES12175163T ES2436744T3 ES 2436744 T3 ES2436744 T3 ES 2436744T3 ES 12175163 T ES12175163 T ES 12175163T ES 2436744 T3 ES2436744 T3 ES 2436744T3
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ES
Spain
Prior art keywords
flow
port
waste
mass spectrometer
liquid chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES12175163.0T
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English (en)
Spanish (es)
Inventor
Tongbo Jiang
Cheryl Follo
Maurice G. Phelan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EMD Millipore Corp
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EMD Millipore Corp
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Publication of ES2436744T3 publication Critical patent/ES2436744T3/es
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
ES12175163.0T 2007-08-24 2008-08-22 Sistema para derivar un eluyente de cromatografía de líquidos Active ES2436744T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96611607P 2007-08-24 2007-08-24
US966116P 2007-08-24

Publications (1)

Publication Number Publication Date
ES2436744T3 true ES2436744T3 (es) 2014-01-07

Family

ID=40029004

Family Applications (1)

Application Number Title Priority Date Filing Date
ES12175163.0T Active ES2436744T3 (es) 2007-08-24 2008-08-22 Sistema para derivar un eluyente de cromatografía de líquidos

Country Status (7)

Country Link
US (1) US8436297B2 (cg-RX-API-DMAC7.html)
EP (2) EP2508880B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010537197A (cg-RX-API-DMAC7.html)
CN (1) CN101821612A (cg-RX-API-DMAC7.html)
ES (1) ES2436744T3 (cg-RX-API-DMAC7.html)
SG (1) SG183001A1 (cg-RX-API-DMAC7.html)
WO (1) WO2009029232A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2607935C (en) 2005-05-05 2014-07-08 Boston Scientific Limited Preshaped localization catheter and system for graphically reconstructing pulmonary vein ostia
SG183001A1 (en) * 2007-08-24 2012-08-30 Emd Millipore Corp System and method for diversion of a liquid chromatography eluant
US8212207B2 (en) * 2007-08-24 2012-07-03 Emd Millipore Corporation Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry
CN103293253B (zh) * 2013-05-24 2015-04-01 中国科学院过程工程研究所 生物技术药物高效纯化分析系统及其药物分离检测方法
US10371674B2 (en) * 2016-04-13 2019-08-06 Horiba Stec, Co., Ltd. Chromatograph sampler and method for operating chromatograph sampler
RU2653570C1 (ru) * 2017-07-14 2018-05-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр питания, биотехнологии и безопасности пищи Способ количественного определения органических кислот (уксусной, яблочной, молочной) и углеводов (мальтозы, глюкозы, фруктозы) в полупродуктах спиртового производства методом высокоэффективной жидкостной хроматографии
CN109270192B (zh) * 2018-12-02 2024-02-02 太湖流域水文水资源监测中心（太湖流域水环境监测中心） 用于水产品磺胺类抗生素检测的前处理装置、方法和用途
JP7297799B2 (ja) 2019-02-04 2023-06-26 株式会社日立ハイテク 液体クロマトグラフ質量分析装置
GB202219580D0 (en) * 2022-12-22 2023-02-08 Thermo Fisher Scient Bremen Gmbh System and method for delivery of an analyte and a reference

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962042A (en) * 1988-05-25 1990-10-09 The Dow Chemical Company Method for on-column injection gas chromatography
US4891137A (en) * 1989-03-03 1990-01-02 Spectra-Physics, Inc. Method and apparatus for membrane extraction of hydrolysis contaminates
US5693620A (en) * 1991-07-31 1997-12-02 Oncomembrane, Inc. Plasmalopsychosines and plasmalocerebrosides
US5468643A (en) * 1991-08-28 1995-11-21 The United States Of America As Represented By The Department Of Health And Human Services Switching valve system for direct biological sample injection for LC analysis
US5703360A (en) 1996-08-30 1997-12-30 Hewlett-Packard Company Automated calibrant system for use in a liquid separation/mass spectrometry apparatus
US6213122B1 (en) 1997-10-01 2001-04-10 3M Innovative Properties Company Electret fibers and filter webs having a low level of extractable hydrocarbons
US6641783B1 (en) * 1999-02-08 2003-11-04 Charles Pidgeon Chromatographic systems with pre-detector eluent switching
EP1325322A2 (en) * 2000-10-03 2003-07-09 Dionex Corporation Method and system for peak parking in liquid chromatography-mass spectrometer (lc-ms) analysis
US7588725B2 (en) * 2001-04-25 2009-09-15 Biotrove, Inc. High throughput autosampler
US8414774B2 (en) * 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
US7220383B2 (en) * 2001-07-13 2007-05-22 Metara, Inc. Method and instrument for automated analysis of fluid-based processing systems
US7547555B2 (en) * 2002-10-30 2009-06-16 Varian, Inc. Use of temperature and flow profiles in gradient elution based analytical process
US7132080B2 (en) * 2003-08-15 2006-11-07 Metara, Inc. Module for automated matrix removal
JP4258318B2 (ja) * 2003-08-22 2009-04-30 株式会社島津製作所 液体クロマトグラフ質量分析装置
AU2006208702C1 (en) * 2005-01-25 2011-12-08 Bayer Intellectual Property Gmbh Method of analyzing phosphorous acid, fosetyl-al or both simultaneously
US8047060B2 (en) * 2005-01-31 2011-11-01 Waters Technologies Corporation Method and apparatus for sample injection in liquid chromatography
CN1936572A (zh) * 2005-09-23 2007-03-28 中国科学院大连化学物理研究所 一种超临界流体萃取－高效液相色谱联用系统
FR2896585B1 (fr) * 2006-01-20 2008-12-05 Commissariat Energie Atomique Introduction d'additifs pour une interface d'ionisation a pression atmospherique en entree d'un spectrometre
JP4913470B2 (ja) * 2006-04-26 2012-04-11 株式会社島津製作所 流路切換えバルブを用いた高速液体クロマトグラフ及び分析方法
WO2008036586A2 (en) * 2006-09-20 2008-03-27 Waters Investments Limited Apparatus and methods of fluid chromatography
ATE529752T1 (de) * 2006-12-21 2011-11-15 Novartis Ag Antikörperquantifizierung
SG183001A1 (en) * 2007-08-24 2012-08-30 Emd Millipore Corp System and method for diversion of a liquid chromatography eluant
US8212207B2 (en) * 2007-08-24 2012-07-03 Emd Millipore Corporation Method of detecting filter extractables in biopharmaceutical products by liquid chromatography-mass spectrometry
US8106351B2 (en) * 2008-08-08 2012-01-31 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin
US7834313B2 (en) * 2008-08-08 2010-11-16 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin

Also Published As

Publication number Publication date
WO2009029232A1 (en) 2009-03-05
US20110114833A1 (en) 2011-05-19
EP2181325A1 (en) 2010-05-05
CN101821612A (zh) 2010-09-01
US8436297B2 (en) 2013-05-07
EP2508880A1 (en) 2012-10-10
JP2010537197A (ja) 2010-12-02
SG183001A1 (en) 2012-08-30
EP2508880B1 (en) 2013-11-13

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