SG183001A1 - System and method for diversion of a liquid chromatography eluant - Google Patents

System and method for diversion of a liquid chromatography eluant Download PDF

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Publication number
SG183001A1
SG183001A1 SG2012049920A SG2012049920A SG183001A1 SG 183001 A1 SG183001 A1 SG 183001A1 SG 2012049920 A SG2012049920 A SG 2012049920A SG 2012049920 A SG2012049920 A SG 2012049920A SG 183001 A1 SG183001 A1 SG 183001A1
Authority
SG
Singapore
Prior art keywords
port
flow
extractables
waste
liquid chromatography
Prior art date
Application number
SG2012049920A
Other languages
English (en)
Inventor
Tongbo Jiang
Cheryl Follo
Maurice G Phelan
Original Assignee
Emd Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Emd Millipore Corp filed Critical Emd Millipore Corp
Publication of SG183001A1 publication Critical patent/SG183001A1/en

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/38Flow patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/84Preparation of the fraction to be distributed

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
SG2012049920A 2007-08-24 2008-08-22 System and method for diversion of a liquid chromatography eluant SG183001A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96611607P 2007-08-24 2007-08-24

Publications (1)

Publication Number Publication Date
SG183001A1 true SG183001A1 (en) 2012-08-30

Family

ID=40029004

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012049920A SG183001A1 (en) 2007-08-24 2008-08-22 System and method for diversion of a liquid chromatography eluant

Country Status (7)

Country Link
US (1) US8436297B2 (cg-RX-API-DMAC7.html)
EP (2) EP2181325A1 (cg-RX-API-DMAC7.html)
JP (1) JP2010537197A (cg-RX-API-DMAC7.html)
CN (1) CN101821612A (cg-RX-API-DMAC7.html)
ES (1) ES2436744T3 (cg-RX-API-DMAC7.html)
SG (1) SG183001A1 (cg-RX-API-DMAC7.html)
WO (1) WO2009029232A1 (cg-RX-API-DMAC7.html)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1876985B1 (en) 2005-05-05 2016-08-31 Boston Scientific Scimed, Inc. System for graphically reconstructing pulmonary vein ostia with preshaped localization catheter
WO2009029232A1 (en) * 2007-08-24 2009-03-05 Millipore Corporation System and method for diversion of a liquid chromatography eluant
CN101815939A (zh) 2007-08-24 2010-08-25 密理博公司 以液相色谱质谱法检测生物药剂产品中的过滤器可提取物的方法
CN103293253B (zh) * 2013-05-24 2015-04-01 中国科学院过程工程研究所 生物技术药物高效纯化分析系统及其药物分离检测方法
JP6918555B2 (ja) * 2016-04-13 2021-08-11 株式会社堀場エステック クロマトグラフ用サンプラ及びクロマトグラフ用サンプラの操作方法
RU2653570C1 (ru) * 2017-07-14 2018-05-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр питания, биотехнологии и безопасности пищи Способ количественного определения органических кислот (уксусной, яблочной, молочной) и углеводов (мальтозы, глюкозы, фруктозы) в полупродуктах спиртового производства методом высокоэффективной жидкостной хроматографии
CN109270192B (zh) * 2018-12-02 2024-02-02 太湖流域水文水资源监测中心(太湖流域水环境监测中心) 用于水产品磺胺类抗生素检测的前处理装置、方法和用途
JP7297799B2 (ja) * 2019-02-04 2023-06-26 株式会社日立ハイテク 液体クロマトグラフ質量分析装置
GB202219580D0 (en) * 2022-12-22 2023-02-08 Thermo Fisher Scient Bremen Gmbh System and method for delivery of an analyte and a reference

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962042A (en) * 1988-05-25 1990-10-09 The Dow Chemical Company Method for on-column injection gas chromatography
US4891137A (en) * 1989-03-03 1990-01-02 Spectra-Physics, Inc. Method and apparatus for membrane extraction of hydrolysis contaminates
US5693620A (en) * 1991-07-31 1997-12-02 Oncomembrane, Inc. Plasmalopsychosines and plasmalocerebrosides
US5468643A (en) * 1991-08-28 1995-11-21 The United States Of America As Represented By The Department Of Health And Human Services Switching valve system for direct biological sample injection for LC analysis
US5703360A (en) 1996-08-30 1997-12-30 Hewlett-Packard Company Automated calibrant system for use in a liquid separation/mass spectrometry apparatus
US6213122B1 (en) 1997-10-01 2001-04-10 3M Innovative Properties Company Electret fibers and filter webs having a low level of extractable hydrocarbons
AU2986400A (en) 1999-02-08 2000-08-25 Admetric Biochem Inc. Chromatographic system with pre-detector eluent switching
JP3764421B2 (ja) * 2000-10-03 2006-04-05 ダイオネックス コーポレイション 液体クロマトグラフィ−質量分析計(lc−ms)分析におけるピークパーキングのための方法及びシステム
US8414774B2 (en) * 2001-04-25 2013-04-09 Agilent Technologies, Inc. Systems and methods for high-throughput screening of fluidic samples
US7588725B2 (en) * 2001-04-25 2009-09-15 Biotrove, Inc. High throughput autosampler
US7220383B2 (en) 2001-07-13 2007-05-22 Metara, Inc. Method and instrument for automated analysis of fluid-based processing systems
ATE437359T1 (de) * 2002-10-30 2009-08-15 Varian Inc Verwendung von temperatur- und strömungsprofilen bei analytischen prozessen auf gradientenelutionsbasis
US7132080B2 (en) * 2003-08-15 2006-11-07 Metara, Inc. Module for automated matrix removal
JP4258318B2 (ja) * 2003-08-22 2009-04-30 株式会社島津製作所 液体クロマトグラフ質量分析装置
JP5028275B2 (ja) * 2005-01-25 2012-09-19 バイエル・クロップサイエンス・アーゲー 亜リン酸、ホセチル−Al又は両者を同時に分析する方法
US8047060B2 (en) * 2005-01-31 2011-11-01 Waters Technologies Corporation Method and apparatus for sample injection in liquid chromatography
CN1936572A (zh) * 2005-09-23 2007-03-28 中国科学院大连化学物理研究所 一种超临界流体萃取-高效液相色谱联用系统
FR2896585B1 (fr) * 2006-01-20 2008-12-05 Commissariat Energie Atomique Introduction d'additifs pour une interface d'ionisation a pression atmospherique en entree d'un spectrometre
JP4913470B2 (ja) * 2006-04-26 2012-04-11 株式会社島津製作所 流路切換えバルブを用いた高速液体クロマトグラフ及び分析方法
WO2008036586A2 (en) * 2006-09-20 2008-03-27 Waters Investments Limited Apparatus and methods of fluid chromatography
ATE529752T1 (de) * 2006-12-21 2011-11-15 Novartis Ag Antikörperquantifizierung
CN101815939A (zh) 2007-08-24 2010-08-25 密理博公司 以液相色谱质谱法检测生物药剂产品中的过滤器可提取物的方法
WO2009029232A1 (en) * 2007-08-24 2009-03-05 Millipore Corporation System and method for diversion of a liquid chromatography eluant
US7834313B2 (en) * 2008-08-08 2010-11-16 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin
US8106351B2 (en) * 2008-08-08 2012-01-31 Quest Diagnostics Investments Incorporated Mass spectrometry assay for plasma-renin

Also Published As

Publication number Publication date
EP2181325A1 (en) 2010-05-05
JP2010537197A (ja) 2010-12-02
WO2009029232A1 (en) 2009-03-05
US8436297B2 (en) 2013-05-07
EP2508880A1 (en) 2012-10-10
ES2436744T3 (es) 2014-01-07
CN101821612A (zh) 2010-09-01
EP2508880B1 (en) 2013-11-13
US20110114833A1 (en) 2011-05-19

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