ES2422260T3 - Aparato de plasma para el tratamiento selectivo de células electroporadas - Google Patents

Aparato de plasma para el tratamiento selectivo de células electroporadas

Info

Publication number
ES2422260T3
ES2422260T3 ES09710903T ES09710903T ES2422260T3 ES 2422260 T3 ES2422260 T3 ES 2422260T3 ES 09710903 T ES09710903 T ES 09710903T ES 09710903 T ES09710903 T ES 09710903T ES 2422260 T3 ES2422260 T3 ES 2422260T3
Authority
ES
Spain
Prior art keywords
plasma apparatus
electroporated cells
selective treatment
plasma
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES09710903T
Other languages
English (en)
Inventor
Manfred Stieber
Klaus-Dieter Weltmann
Woedtke Thomas Von
Christian Wilke
Uwe Ehrenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Inp Greifswald Leibniz Inst fur Plasmaforschung und Technologie E V
Original Assignee
Inp Greifswald Leibniz Inst fur Plasmaforschung und Technologie E V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inp Greifswald Leibniz Inst fur Plasmaforschung und Technologie E V filed Critical Inp Greifswald Leibniz Inst fur Plasmaforschung und Technologie E V
Application granted granted Critical
Publication of ES2422260T3 publication Critical patent/ES2422260T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/44—Applying ionised fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/14—Plasma, i.e. ionised gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H1/00—Generating plasma; Handling plasma
    • H05H1/24—Generating plasma
    • H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
    • H05H1/2439—Surface discharges, e.g. air flow control
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H2245/00—Applications of plasma devices
    • H05H2245/30—Medical applications
    • H05H2245/32—Surgery, e.g. scalpels, blades or bistoury; Treatments inside the body
    • H—ELECTRICITY
    • H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
    • H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
    • H05H2245/00—Applications of plasma devices
    • H05H2245/30—Medical applications
    • H05H2245/34—Skin treatments, e.g. disinfection or wound treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Sustainable Development (AREA)
  • Electromagnetism (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Plasma Technology (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

Dispositivo para el tratamiento de células vivas mediante un plasma con electroporación simultánea delas células, caracterizado porque el dispositivo presenta, además del equipo convencional para la electroporación,un equipo para la generación de un plasma.
ES09710903T 2008-02-12 2009-02-12 Aparato de plasma para el tratamiento selectivo de células electroporadas Active ES2422260T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008008614A DE102008008614A1 (de) 2008-02-12 2008-02-12 Plama-Gerät zur selektiven Behandlung elektroporierter Zellen
PCT/EP2009/051650 WO2009101143A1 (de) 2008-02-12 2009-02-12 Plasma-gerät zur selektiven behandlung elektroporierter zellen

Publications (1)

Publication Number Publication Date
ES2422260T3 true ES2422260T3 (es) 2013-09-10

Family

ID=40688466

Family Applications (1)

Application Number Title Priority Date Filing Date
ES09710903T Active ES2422260T3 (es) 2008-02-12 2009-02-12 Aparato de plasma para el tratamiento selectivo de células electroporadas

Country Status (6)

Country Link
US (1) US8894644B2 (es)
EP (1) EP2254664B1 (es)
JP (1) JP5319709B2 (es)
DE (1) DE102008008614A1 (es)
ES (1) ES2422260T3 (es)
WO (1) WO2009101143A1 (es)

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EP3415172A1 (en) 2009-06-16 2018-12-19 TheraDep Technologies, Inc. Wound healing device
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DE202009011521U1 (de) * 2009-08-25 2010-12-30 INP Greifswald Leibniz-Institut für Plasmaforschung und Technologie e. V. Plasma-Manschette
DE102009047220A1 (de) 2009-11-27 2011-06-01 Leibniz-Institut für Plasmaforschung und Technologie e.V. Vorrichtung und Verfahren zur Erzeugung eines gepulsten Anisothermen Atmosphärendruck-Plasmas
RU2603296C2 (ru) 2010-11-02 2016-11-27 Ю.С. Пейтент Инновейшнс Система и способ электрохирургической резки проводящим газом для лечения струпьев, уплотнения сосудов и тканей
US10213614B2 (en) * 2011-06-01 2019-02-26 U.S. Patent Innovations, LLC System and method for cold plasma therapy
CN102321606B (zh) * 2011-08-04 2014-01-01 大连大学 一种利用大气压冷等离子体提高细胞膜通透性的方法
DE102011055326A1 (de) * 2011-11-14 2013-05-16 Adelheid Mirwald Verfahren zur Sterilisation von Personen
JP2013191404A (ja) * 2012-03-14 2013-09-26 Toyota Gakuen サンプルと密着可能なマイクロプラズマ用ノズル
GB2509063A (en) * 2012-12-18 2014-06-25 Linde Ag Plasma device with earth electrode
WO2014106258A1 (en) * 2012-12-31 2014-07-03 Cold Plasma Medical Technologies, Inc. Cold plasma electroporation of medication and associated methods
US9339572B2 (en) 2013-03-15 2016-05-17 EP Technologies LLC Methods and solutions for killing or deactivating spores
DE102014105720A1 (de) 2014-04-23 2015-10-29 Inp Greifswald E.V. Wirkauflage und Verfahren zur Behandlung einer Oberfläche
US10405913B2 (en) 2014-10-06 2019-09-10 Us Patent Innovations, Llc Cold plasma scalpel
CN107106225B (zh) 2014-11-19 2021-05-28 技术研究及发展基金有限公司 冷等离子体生成系统
US11490947B2 (en) 2015-05-15 2022-11-08 Clear Intradermal Technologies, Inc. Tattoo removal using a liquid-gas mixture with plasma gas bubbles
CA2986031C (en) 2015-05-15 2024-03-19 ClearIt, LLC Systems and methods for tattoo removal using cold plasma
US11123446B2 (en) 2015-07-28 2021-09-21 Gojo Industries, Inc. Scrubbing device for cleaning, sanitizing or disinfecting
US10897894B2 (en) 2015-08-31 2021-01-26 Gojo Industries, Inc. Methods of and system for generating antimicrobial wipes
EP3411159A1 (en) 2016-02-01 2018-12-12 TheraDep Technologies, Inc. Systems and methods for delivering therapeutic agents
US10765850B2 (en) 2016-05-12 2020-09-08 Gojo Industries, Inc. Methods and systems for trans-tissue substance delivery using plasmaporation
KR101773846B1 (ko) * 2016-05-30 2017-09-01 광운대학교 산학협력단 가스 공급형 비열 플라즈마 피부염 치료기 및 이의 용도
KR101773847B1 (ko) * 2016-05-30 2017-09-01 광운대학교 산학협력단 가스 공급형 비열 플라즈마 피부 미용기 및 이의 용도
GB201617173D0 (en) 2016-10-10 2016-11-23 Univ Strathclyde Plasma accelerator
US20180104503A1 (en) * 2016-10-15 2018-04-19 Michelle Wirtz Cold atmospheric plasma treatment of actinic keratosis and non-melanoma skin cancer
WO2018089577A1 (en) 2016-11-10 2018-05-17 EP Technologies LLC Methods and systems for generating plasma activated liquid
DE102017107210A1 (de) 2017-04-04 2018-10-04 Universität Rostock Vorrichtung zur keimlastreduktion
DE102017120902A1 (de) * 2017-09-11 2019-03-14 Cinogy Gmbh Plasma-Behandlungsgerät
US11690998B2 (en) 2017-10-31 2023-07-04 Theradep Technologies, Inc. Methods of treating bacterial infections
KR101970644B1 (ko) * 2017-11-22 2019-08-13 주식회사 하이로닉 경피 전달 촉진을 위한 복합 시술 장치
KR102132370B1 (ko) * 2018-03-13 2020-08-05 주식회사 지씨에스 피부관리장치, 피부관리장치의 구동방법 및 컴퓨터 판독가능 기록매체
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Also Published As

Publication number Publication date
JP5319709B2 (ja) 2013-10-16
DE102008008614A1 (de) 2009-08-13
US20110112528A1 (en) 2011-05-12
WO2009101143A1 (de) 2009-08-20
JP2011514814A (ja) 2011-05-12
EP2254664B1 (de) 2013-04-24
EP2254664A1 (de) 2010-12-01
US8894644B2 (en) 2014-11-25

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