ES2422260T3 - Aparato de plasma para el tratamiento selectivo de células electroporadas - Google Patents
Aparato de plasma para el tratamiento selectivo de células electroporadasInfo
- Publication number
- ES2422260T3 ES2422260T3 ES09710903T ES09710903T ES2422260T3 ES 2422260 T3 ES2422260 T3 ES 2422260T3 ES 09710903 T ES09710903 T ES 09710903T ES 09710903 T ES09710903 T ES 09710903T ES 2422260 T3 ES2422260 T3 ES 2422260T3
- Authority
- ES
- Spain
- Prior art keywords
- plasma apparatus
- electroporated cells
- selective treatment
- plasma
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/44—Applying ionised fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/14—Plasma, i.e. ionised gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/02—Electrical or electromagnetic means, e.g. for electroporation or for cell fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N13/00—Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H1/00—Generating plasma; Handling plasma
- H05H1/24—Generating plasma
- H05H1/2406—Generating plasma using dielectric barrier discharges, i.e. with a dielectric interposed between the electrodes
- H05H1/2439—Surface discharges, e.g. air flow control
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H2245/00—Applications of plasma devices
- H05H2245/30—Medical applications
- H05H2245/32—Surgery, e.g. scalpels, blades or bistoury; Treatments inside the body
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H2245/00—Applications of plasma devices
- H05H2245/30—Medical applications
- H05H2245/34—Skin treatments, e.g. disinfection or wound treatment
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Plasma & Fusion (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Electromagnetism (AREA)
- Sustainable Development (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plasma Technology (AREA)
- Medicinal Preparation (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Electrotherapy Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
Abstract
Dispositivo para el tratamiento de células vivas mediante un plasma con electroporación simultánea delas células, caracterizado porque el dispositivo presenta, además del equipo convencional para la electroporación,un equipo para la generación de un plasma.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102008008614A DE102008008614A1 (de) | 2008-02-12 | 2008-02-12 | Plama-Gerät zur selektiven Behandlung elektroporierter Zellen |
PCT/EP2009/051650 WO2009101143A1 (de) | 2008-02-12 | 2009-02-12 | Plasma-gerät zur selektiven behandlung elektroporierter zellen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2422260T3 true ES2422260T3 (es) | 2013-09-10 |
Family
ID=40688466
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09710903T Active ES2422260T3 (es) | 2008-02-12 | 2009-02-12 | Aparato de plasma para el tratamiento selectivo de células electroporadas |
Country Status (6)
Country | Link |
---|---|
US (1) | US8894644B2 (es) |
EP (1) | EP2254664B1 (es) |
JP (1) | JP5319709B2 (es) |
DE (1) | DE102008008614A1 (es) |
ES (1) | ES2422260T3 (es) |
WO (1) | WO2009101143A1 (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3415172A1 (en) | 2009-06-16 | 2018-12-19 | TheraDep Technologies, Inc. | Wound healing device |
DE102009028462A1 (de) * | 2009-08-11 | 2011-03-24 | Leibniz-Institut für Plasmaforschung und Technologie e.V. | Vorrichtung und Verfahren zur Behandlung von lebenden Zellen mittels eines Plasmas |
DE202009011521U1 (de) * | 2009-08-25 | 2010-12-30 | INP Greifswald Leibniz-Institut für Plasmaforschung und Technologie e. V. | Plasma-Manschette |
DE102009047220A1 (de) | 2009-11-27 | 2011-06-01 | Leibniz-Institut für Plasmaforschung und Technologie e.V. | Vorrichtung und Verfahren zur Erzeugung eines gepulsten Anisothermen Atmosphärendruck-Plasmas |
RU2603296C2 (ru) | 2010-11-02 | 2016-11-27 | Ю.С. Пейтент Инновейшнс | Система и способ электрохирургической резки проводящим газом для лечения струпьев, уплотнения сосудов и тканей |
US10213614B2 (en) * | 2011-06-01 | 2019-02-26 | U.S. Patent Innovations, LLC | System and method for cold plasma therapy |
CN102321606B (zh) * | 2011-08-04 | 2014-01-01 | 大连大学 | 一种利用大气压冷等离子体提高细胞膜通透性的方法 |
DE102011055326A1 (de) * | 2011-11-14 | 2013-05-16 | Adelheid Mirwald | Verfahren zur Sterilisation von Personen |
JP2013191404A (ja) * | 2012-03-14 | 2013-09-26 | Toyota Gakuen | サンプルと密着可能なマイクロプラズマ用ノズル |
GB2509063A (en) * | 2012-12-18 | 2014-06-25 | Linde Ag | Plasma device with earth electrode |
WO2014106258A1 (en) * | 2012-12-31 | 2014-07-03 | Cold Plasma Medical Technologies, Inc. | Cold plasma electroporation of medication and associated methods |
US9339572B2 (en) | 2013-03-15 | 2016-05-17 | EP Technologies LLC | Methods and solutions for killing or deactivating spores |
DE102014105720A1 (de) | 2014-04-23 | 2015-10-29 | Inp Greifswald E.V. | Wirkauflage und Verfahren zur Behandlung einer Oberfläche |
US10405913B2 (en) | 2014-10-06 | 2019-09-10 | Us Patent Innovations, Llc | Cold plasma scalpel |
CN107106225B (zh) | 2014-11-19 | 2021-05-28 | 技术研究及发展基金有限公司 | 冷等离子体生成系统 |
US11490947B2 (en) | 2015-05-15 | 2022-11-08 | Clear Intradermal Technologies, Inc. | Tattoo removal using a liquid-gas mixture with plasma gas bubbles |
CA2986031C (en) | 2015-05-15 | 2024-03-19 | ClearIt, LLC | Systems and methods for tattoo removal using cold plasma |
US11123446B2 (en) | 2015-07-28 | 2021-09-21 | Gojo Industries, Inc. | Scrubbing device for cleaning, sanitizing or disinfecting |
US10897894B2 (en) | 2015-08-31 | 2021-01-26 | Gojo Industries, Inc. | Methods of and system for generating antimicrobial wipes |
EP3411159A1 (en) | 2016-02-01 | 2018-12-12 | TheraDep Technologies, Inc. | Systems and methods for delivering therapeutic agents |
US10765850B2 (en) | 2016-05-12 | 2020-09-08 | Gojo Industries, Inc. | Methods and systems for trans-tissue substance delivery using plasmaporation |
KR101773846B1 (ko) * | 2016-05-30 | 2017-09-01 | 광운대학교 산학협력단 | 가스 공급형 비열 플라즈마 피부염 치료기 및 이의 용도 |
KR101773847B1 (ko) * | 2016-05-30 | 2017-09-01 | 광운대학교 산학협력단 | 가스 공급형 비열 플라즈마 피부 미용기 및 이의 용도 |
GB201617173D0 (en) | 2016-10-10 | 2016-11-23 | Univ Strathclyde | Plasma accelerator |
US20180104503A1 (en) * | 2016-10-15 | 2018-04-19 | Michelle Wirtz | Cold atmospheric plasma treatment of actinic keratosis and non-melanoma skin cancer |
WO2018089577A1 (en) | 2016-11-10 | 2018-05-17 | EP Technologies LLC | Methods and systems for generating plasma activated liquid |
DE102017107210A1 (de) | 2017-04-04 | 2018-10-04 | Universität Rostock | Vorrichtung zur keimlastreduktion |
DE102017120902A1 (de) * | 2017-09-11 | 2019-03-14 | Cinogy Gmbh | Plasma-Behandlungsgerät |
US11690998B2 (en) | 2017-10-31 | 2023-07-04 | Theradep Technologies, Inc. | Methods of treating bacterial infections |
KR101970644B1 (ko) * | 2017-11-22 | 2019-08-13 | 주식회사 하이로닉 | 경피 전달 촉진을 위한 복합 시술 장치 |
KR102132370B1 (ko) * | 2018-03-13 | 2020-08-05 | 주식회사 지씨에스 | 피부관리장치, 피부관리장치의 구동방법 및 컴퓨터 판독가능 기록매체 |
KR102030528B1 (ko) * | 2018-03-29 | 2019-11-08 | 주식회사 지씨에스 | 피부관리장치 및 그 장치의 구동방법 |
WO2019232438A1 (en) * | 2018-06-01 | 2019-12-05 | Yan Dayun | Method and system of sensitizing cancer cells to chemical treatment by plasma based activation |
EP3607909A1 (en) * | 2018-08-10 | 2020-02-12 | Albert-Ludwigs-Universität Freiburg | Atmospheric pressure plasma jet device |
WO2020131544A1 (en) | 2018-12-19 | 2020-06-25 | ClearIt, LLC | Systems and methods for tattoo removal using an applied electric field |
DE102022100053A1 (de) | 2022-01-03 | 2023-07-06 | Snejan Dimitrov Ivantchev | Topisches Mittel zur Behandlung von Alopecia areata (SNEZHALIN)) |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5993434A (en) | 1993-04-01 | 1999-11-30 | Genetronics, Inc. | Method of treatment using electroporation mediated delivery of drugs and genes |
SE513814C2 (sv) | 1998-03-31 | 2000-11-06 | Aditus Medical Ab | Anordning för behandling av sjukdomar med elektriska fält |
IT1320187B1 (it) | 2000-04-21 | 2003-11-26 | Igea Srl | Dispositivo e metodo di elettro-porazione che fornisce un segnalemodulato sotto il controllo continuo della elettro-permeabilizzazione |
US20020122896A1 (en) * | 2001-03-02 | 2002-09-05 | Skion Corporation | Capillary discharge plasma apparatus and method for surface treatment using the same |
JP4191951B2 (ja) * | 2002-04-25 | 2008-12-03 | ソントル ファルマペプティド | 抗微生物剤投与装置および組立品 |
US20060148737A1 (en) * | 2002-12-31 | 2006-07-06 | The John Hopkins University | Wound healing method and kits |
US8455228B2 (en) * | 2003-07-16 | 2013-06-04 | University Of South Florida | Method to facilitate directed delivery and electroporation using a charged stream |
AU2004277376B2 (en) * | 2003-07-18 | 2011-06-02 | Eastern Virginia Medical School | Apparatus for generating electrical pulses and methods of using the same |
US8101169B2 (en) * | 2005-02-23 | 2012-01-24 | The Board Of Trustees Of The Leland Stanford Junior University | Ocular gene therapy using avalanche-mediated transfection |
CA2605650A1 (en) * | 2005-04-25 | 2006-11-02 | Drexel University | Methods for non-thermal application of gas plasma to living tissue |
DE102005029148B4 (de) * | 2005-06-23 | 2013-10-31 | Eisenmann Ag | Vorrichtung zur Luftaufbereitung sowie Oberflächenbehandlungsanlage mit derselben |
US7608839B2 (en) * | 2005-08-05 | 2009-10-27 | Mcgill University | Plasma source and applications thereof |
DE102006019664B4 (de) * | 2006-04-27 | 2017-01-05 | Leibniz-Institut für Plasmaforschung und Technologie e.V. | Kaltplasma-Handgerät zur Plasma-Behandlung von Oberflächen |
DE102007025452A1 (de) * | 2007-05-31 | 2008-12-04 | Ernst-Moritz-Arndt-Universität Greifswald | Verfahren zur Beschichtung von Oberflächen mit Mikro- und Nanopartikeln mit Hilfe von Plasmaverfahren |
JP4844488B2 (ja) * | 2007-07-11 | 2011-12-28 | 株式会社Ihi | 高電圧パルス制御による選択的液体処理方法 |
-
2008
- 2008-02-12 DE DE102008008614A patent/DE102008008614A1/de not_active Withdrawn
-
2009
- 2009-02-12 ES ES09710903T patent/ES2422260T3/es active Active
- 2009-02-12 JP JP2010546337A patent/JP5319709B2/ja not_active Expired - Fee Related
- 2009-02-12 EP EP09710903.7A patent/EP2254664B1/de not_active Not-in-force
- 2009-02-12 WO PCT/EP2009/051650 patent/WO2009101143A1/de active Application Filing
-
2010
- 2010-08-12 US US12/855,177 patent/US8894644B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP5319709B2 (ja) | 2013-10-16 |
DE102008008614A1 (de) | 2009-08-13 |
US20110112528A1 (en) | 2011-05-12 |
WO2009101143A1 (de) | 2009-08-20 |
JP2011514814A (ja) | 2011-05-12 |
EP2254664B1 (de) | 2013-04-24 |
EP2254664A1 (de) | 2010-12-01 |
US8894644B2 (en) | 2014-11-25 |
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