ES2399846T3 - Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica - Google Patents
Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica Download PDFInfo
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- ES2399846T3 ES2399846T3 ES08794174T ES08794174T ES2399846T3 ES 2399846 T3 ES2399846 T3 ES 2399846T3 ES 08794174 T ES08794174 T ES 08794174T ES 08794174 T ES08794174 T ES 08794174T ES 2399846 T3 ES2399846 T3 ES 2399846T3
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- Pharmacology & Pharmacy (AREA)
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- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Psychology (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US957523P | 2007-08-23 | ||
| US957525P | 2007-08-23 | ||
| PCT/SE2008/050950 WO2009025618A1 (en) | 2007-08-23 | 2008-08-22 | Mipo inhibitors for the treatment of huntington's disease and multiple system atrophy |
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| ES2399846T3 true ES2399846T3 (es) | 2013-04-03 |
Family
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Family Applications (1)
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| ES08794174T Active ES2399846T3 (es) | 2007-08-23 | 2008-08-22 | Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica |
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| AR039385A1 (es) * | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
| MY140748A (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
| TW200806667A (en) * | 2006-04-13 | 2008-02-01 | Astrazeneca Ab | New compounds |
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| US20090054468A1 (en) * | 2007-08-23 | 2009-02-26 | Astrazeneca Ab | New Use 938 |
| WO2012051036A1 (en) | 2010-10-11 | 2012-04-19 | Merck Sharp & Dohme Corp. | Quinazolinone-type compounds as crth2 antagonists |
| BR112014011254A2 (pt) | 2011-11-11 | 2017-05-16 | Pfizer | 2-tiopirimidinonas |
| ES2587954T3 (es) * | 2012-03-29 | 2016-10-27 | Basf Se | Compuestos de hetero-bicíclicos N-sustituidos y derivados para combatir plagas animales II |
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| CR20170498A (es) | 2015-05-05 | 2018-01-26 | Pfizer | 2-tiopirimidinonas |
| CA3067591A1 (en) * | 2017-06-28 | 2019-01-03 | Ptc Therapeutics, Inc. | Methods for treating huntington's disease |
| IL272043B (en) * | 2017-07-17 | 2022-09-01 | Astrazeneca Ab | mpo inhibitors for use in medicine |
| AU2020363903A1 (en) * | 2019-10-10 | 2022-03-24 | Biohaven Therapeutics Ltd. | Prodrugs of myeloperoxidase inhibitors |
| AU2021230370A1 (en) * | 2020-03-05 | 2022-10-20 | Biohaven Therapeutics Ltd. | Method of treating amyotrophic lateral sclerosis with myeloperoxidase inhibitor |
| WO2021226161A1 (en) * | 2020-05-06 | 2021-11-11 | Biohaven Therapeutics Ltd. | Process for the preparation of verdiperstat |
| CN115403584B (zh) * | 2021-05-26 | 2024-04-02 | 长春金赛药业有限责任公司 | 2-硫代-2,3-二氢嘧啶-4-酮衍生物、药物组合物及其制备方法和应用 |
| JP2025528217A (ja) | 2022-08-18 | 2025-08-26 | アストラゼネカ・アクチエボラーグ | ミエロペルオキシダーゼの阻害剤 |
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| EP4624473A1 (en) * | 2022-12-09 | 2025-10-01 | Shenzhen Salubris Pharmaceuticals Co., Ltd. | Pyrrolo[3,2-d]pyrimidin-4-one derivative, and preparation method therefor and medical use thereof |
| WO2024163892A1 (en) * | 2023-02-02 | 2024-08-08 | University Of Virginia Patent Foundation | Myeloperoxidase (mpo) inhibition as a treatment target for delayed cerebral injury (dci) in aneurysmal subarachnoid hemorrhage (sah) |
| WO2025172474A1 (en) | 2024-02-15 | 2025-08-21 | Astrazeneca Ab | Inhibitors of myeloperoxidase |
| WO2025190901A1 (en) | 2024-03-13 | 2025-09-18 | Institut National de la Santé et de la Recherche Médicale | Use of myeloperoxidase (mpo) inhibitors for promoting cd8+ t cell responses |
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| ES2264210T3 (es) * | 1997-09-05 | 2006-12-16 | Kyowa Hakko Kogyo Co., Ltd. | Derivados de xantina para el tratamiento de la isquemia cerebral. |
| GB0100620D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical cokpounds V |
| GB0100623D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds IV |
| KR20150080013A (ko) * | 2002-01-28 | 2015-07-08 | 교와 핫꼬 기린 가부시키가이샤 | 운동성 질환에 걸린 환자의 치료용 조성물 |
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| AR066936A1 (es) * | 2007-06-13 | 2009-09-23 | Astrazeneca Ab | 3 - (2r - tetrahidrofuril - metil) - 2 - tioxantina. composiciones farmaceuticas. |
| US20090054468A1 (en) * | 2007-08-23 | 2009-02-26 | Astrazeneca Ab | New Use 938 |
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- 2008-08-22 KR KR1020107003835A patent/KR101588464B1/ko not_active Expired - Fee Related
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- 2008-08-22 CA CA2698205A patent/CA2698205C/en not_active Expired - Fee Related
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- 2008-08-22 PL PL08794174T patent/PL2200616T3/pl unknown
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2015
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2020
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