ES2399846T3 - Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica - Google Patents
Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica Download PDFInfo
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- ES2399846T3 ES2399846T3 ES08794174T ES08794174T ES2399846T3 ES 2399846 T3 ES2399846 T3 ES 2399846T3 ES 08794174 T ES08794174 T ES 08794174T ES 08794174 T ES08794174 T ES 08794174T ES 2399846 T3 ES2399846 T3 ES 2399846T3
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
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| US95752507P | 2007-08-23 | 2007-08-23 | |
| US95752307P | 2007-08-23 | 2007-08-23 | |
| US957525P | 2007-08-23 | ||
| US957523P | 2007-08-23 | ||
| PCT/SE2008/050950 WO2009025618A1 (en) | 2007-08-23 | 2008-08-22 | Mipo inhibitors for the treatment of huntington's disease and multiple system atrophy |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2399846T3 true ES2399846T3 (es) | 2013-04-03 |
Family
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Family Applications (1)
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| ES08794174T Active ES2399846T3 (es) | 2007-08-23 | 2008-08-22 | Inhibidores de MPO para el tratamiento de la enfermedad de Huntington y la atrofia multisistémica |
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| PL (1) | PL2200616T3 (enExample) |
| PT (1) | PT2200616E (enExample) |
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| SI (1) | SI2200616T1 (enExample) |
| WO (1) | WO2009025618A1 (enExample) |
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| AR039385A1 (es) * | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
| MY140748A (en) | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
| UY30267A1 (es) * | 2006-04-13 | 2007-11-30 | Astrazeneca Ab | Nuevos derivados de la tioxantina , composiciones farmacéuticas que los contienen, procedimientos de preparacion y aplicaciones |
| TW200804383A (en) * | 2006-06-05 | 2008-01-16 | Astrazeneca Ab | New compounds |
| US20090054468A1 (en) * | 2007-08-23 | 2009-02-26 | Astrazeneca Ab | New Use 938 |
| EP2627178B1 (en) | 2010-10-11 | 2018-05-02 | Merck Sharp & Dohme Corp. | Quinazolinone-type compounds as crth2 antagonists |
| MD20140044A2 (ro) | 2011-11-11 | 2014-08-31 | Pfizer Inc. | 2-Tiopirimidinone şi utilizarea lor pentru tratamentul afecţiunilor cardiovasculare |
| WO2013144088A1 (en) * | 2012-03-29 | 2013-10-03 | Basf Se | N-substituted hetero-bicyclic compounds and derivatives for combating animal pests ii |
| US9616063B2 (en) * | 2014-12-01 | 2017-04-11 | Astrazeneca Ab | 1-[2-(aminomethyl)benzyl]-2-thioxo-1,2,3,5-tetrahydro-4H-pyrrolo[3,2-d]pyrimidin-4-ones as inhibitors of myeloperoxidase |
| CU20170134A7 (es) | 2015-05-05 | 2017-12-08 | Pfizer | 2-tiopirimidinonas |
| US11382918B2 (en) * | 2017-06-28 | 2022-07-12 | Ptc Therapeutics, Inc. | Methods for treating Huntington's Disease |
| AU2018304508B2 (en) * | 2017-07-17 | 2021-06-10 | Astrazeneca Ab | MPO inhibitors for use in medicine |
| MX2022004203A (es) * | 2019-10-10 | 2022-07-04 | Biohaven Therapeutics Ltd | Profarmacos de inhibidores de mieloperoxidasa. |
| BR112022017501A2 (pt) * | 2020-03-05 | 2022-10-18 | Biohaven Therapeutics Ltd | Método de tratamento da esclerose lateral amiotrófica com inibidor de mieloperoxidase |
| MX2022013788A (es) * | 2020-05-06 | 2022-11-30 | Biohaven Therapeutics Ltd | Proceso para la preparacion de verdiperstat. |
| CN115403584B (zh) * | 2021-05-26 | 2024-04-02 | 长春金赛药业有限责任公司 | 2-硫代-2,3-二氢嘧啶-4-酮衍生物、药物组合物及其制备方法和应用 |
| AR130237A1 (es) | 2022-08-18 | 2024-11-20 | Astrazeneca Ab | Inhibidores de mieloperoxidasa |
| US20240091231A1 (en) * | 2022-08-31 | 2024-03-21 | Astrazeneca Ab | Pharmaceutical formulations |
| WO2024120457A1 (zh) * | 2022-12-09 | 2024-06-13 | 深圳信立泰药业股份有限公司 | 一种吡咯并[3,2-d]嘧啶-4-酮类衍生物及其制备方法和医药用途 |
| WO2024163892A1 (en) * | 2023-02-02 | 2024-08-08 | University Of Virginia Patent Foundation | Myeloperoxidase (mpo) inhibition as a treatment target for delayed cerebral injury (dci) in aneurysmal subarachnoid hemorrhage (sah) |
| WO2025172474A1 (en) | 2024-02-15 | 2025-08-21 | Astrazeneca Ab | Inhibitors of myeloperoxidase |
| WO2025190901A1 (en) | 2024-03-13 | 2025-09-18 | Institut National de la Santé et de la Recherche Médicale | Use of myeloperoxidase (mpo) inhibitors for promoting cd8+ t cell responses |
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| US6727259B2 (en) * | 1997-09-05 | 2004-04-27 | Kyowa Hakko Kogyo Co., Ltd. | Remedial agent for neural degeneration |
| GB0100623D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical compounds IV |
| GB0100620D0 (en) * | 2001-01-10 | 2001-02-21 | Vernalis Res Ltd | Chemical cokpounds V |
| PT2942082T (pt) * | 2002-01-28 | 2019-06-06 | Kyowa Hakko Kogyo Kk | Antagonistas do recetor de a2a para utilização no tratamento de distúrbios de movimento |
| AR039385A1 (es) * | 2002-04-19 | 2005-02-16 | Astrazeneca Ab | Derivados de tioxantina como inhibidores de la mieloperoxidasa |
| SE0302756D0 (sv) * | 2003-10-17 | 2003-10-17 | Astrazeneca Ab | Novel Compounds |
| MY140748A (en) * | 2004-12-06 | 2010-01-15 | Astrazeneca Ab | Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy |
| UY30267A1 (es) * | 2006-04-13 | 2007-11-30 | Astrazeneca Ab | Nuevos derivados de la tioxantina , composiciones farmacéuticas que los contienen, procedimientos de preparacion y aplicaciones |
| JP2009539829A (ja) * | 2006-06-05 | 2009-11-19 | アストラゼネカ・アクチエボラーグ | ミエロペルオキシダーゼ阻害剤としてのピロロ［３，２−ｄ］ピリミジン−４−オン誘導体 |
| AR066936A1 (es) * | 2007-06-13 | 2009-09-23 | Astrazeneca Ab | 3 - (2r - tetrahidrofuril - metil) - 2 - tioxantina. composiciones farmaceuticas. |
| US20090054468A1 (en) * | 2007-08-23 | 2009-02-26 | Astrazeneca Ab | New Use 938 |
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2008
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- 2008-08-22 CA CA2698205A patent/CA2698205C/en not_active Expired - Fee Related
- 2008-08-22 PL PL08794174T patent/PL2200616T3/pl unknown
- 2008-08-22 NZ NZ584135A patent/NZ584135A/en not_active IP Right Cessation
- 2008-08-22 HR HRP20130139AT patent/HRP20130139T1/hr unknown
- 2008-08-22 PT PT87941746T patent/PT2200616E/pt unknown
- 2008-08-22 EP EP08794174A patent/EP2200616B1/en active Active
- 2008-08-22 AU AU2008289653A patent/AU2008289653B2/en not_active Ceased
- 2008-08-22 ME MEP-2013-49A patent/ME01510B/me unknown
- 2008-08-22 CN CN201310681047.4A patent/CN103638029A/zh active Pending
- 2008-08-22 ES ES08794174T patent/ES2399846T3/es active Active
- 2008-08-22 WO PCT/SE2008/050950 patent/WO2009025618A1/en not_active Ceased
- 2008-08-22 EA EA201000202A patent/EA017510B1/ru not_active IP Right Cessation
- 2008-08-22 CN CN201610055826.7A patent/CN105687199A/zh active Pending
- 2008-08-22 JP JP2010521817A patent/JP5247804B2/ja active Active
- 2008-08-22 CN CN202110874748.4A patent/CN113633641A/zh active Pending
- 2008-08-22 KR KR1020107003835A patent/KR101588464B1/ko not_active Expired - Fee Related
- 2008-08-22 MY MYPI2010000753A patent/MY155633A/en unknown
- 2008-08-22 DK DK08794174.6T patent/DK2200616T3/da active
- 2008-08-22 SI SI200830893T patent/SI2200616T1/sl unknown
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2010
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2011
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2012
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2013
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- 2013-11-08 US US14/075,790 patent/US20140221400A1/en not_active Abandoned
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2014
- 2014-05-26 PH PH12014501180A patent/PH12014501180A1/en unknown
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2015
- 2015-07-23 IL IL240130A patent/IL240130A0/en unknown
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2018
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2020
- 2020-09-13 US US17/019,276 patent/US20200405724A1/en active Pending
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