ES2387700T3 - Métodos para medir la inhibición de la agregación de plaquetas mediante antagonistas del receptor de trombina - Google Patents
Métodos para medir la inhibición de la agregación de plaquetas mediante antagonistas del receptor de trombina Download PDFInfo
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- ES2387700T3 ES2387700T3 ES08755007T ES08755007T ES2387700T3 ES 2387700 T3 ES2387700 T3 ES 2387700T3 ES 08755007 T ES08755007 T ES 08755007T ES 08755007 T ES08755007 T ES 08755007T ES 2387700 T3 ES2387700 T3 ES 2387700T3
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- thrombin receptor
- thrombin
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- blood sample
- platelet aggregation
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
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- C—CHEMISTRY; METALLURGY
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
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| PCT/US2008/062415 WO2008137673A1 (en) | 2007-05-03 | 2008-05-02 | Methods of measuring inhibition of platelet aggregation by thrombin receptor antagonists |
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| CN (1) | CN101675342A (https=) |
| ES (1) | ES2387700T3 (https=) |
| WO (1) | WO2008137673A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109884326A (zh) * | 2019-03-27 | 2019-06-14 | 深圳优迪生物技术有限公司 | 血小板聚集功能检测试剂盒 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20070243632A1 (en) * | 2003-07-08 | 2007-10-18 | Coller Barry S | Methods for measuring platelet reactivity of patients that have received drug eluting stents |
| ATE536889T1 (de) * | 2003-07-08 | 2011-12-15 | Accumetrics Inc | Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten |
| WO2009152094A2 (en) * | 2008-06-09 | 2009-12-17 | Accumetrics, Inc. | Hubbed dual cannula device for closed container sampling systems |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| EP2371284A1 (en) * | 2010-03-24 | 2011-10-05 | C A Casyso AG | Method and apparatus for determining at least one evaluation parameter of a blood sample |
| WO2011133450A2 (en) | 2010-04-19 | 2011-10-27 | Meso Scale Technologies, Llc. | Serology assays |
| JP5999776B2 (ja) * | 2010-09-15 | 2016-09-28 | デビオファーマ インターナショナル ソシエテ アノニムＤｅｂｉｏｐｈａｒｍ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｓａ | 血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法 |
| RU2559873C2 (ru) * | 2011-04-27 | 2015-08-20 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Миметики поли (adp-рибозы) и способ их получения |
| CN103969228A (zh) * | 2013-02-04 | 2014-08-06 | 百奥泰生物科技(广州)有限公司 | 一种整合素GP IIb/IIIa特异性结合分子巴替非班的生物学效应检测方法 |
| WO2015061733A1 (en) * | 2013-10-25 | 2015-04-30 | Bristol-Meyers Squibb Company | Diagnostic methods for par4 antagonist therapy |
| US10816559B2 (en) | 2014-09-29 | 2020-10-27 | Ca Casyso Ag | Blood testing system and method |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| CN105717263B (zh) * | 2016-03-04 | 2018-01-26 | 北京乐普医疗科技有限责任公司 | 一种检测噻吩并吡啶类抗血小板药物疗效的试剂卡及其使用方法和应用 |
| JP7257333B2 (ja) * | 2017-12-28 | 2023-04-13 | 株式会社カネカ | 細胞凝集抑制剤 |
| CN110051692A (zh) * | 2019-04-12 | 2019-07-26 | 南京市第一医院 | 一种血小板定向释放生长因子的组合物及其制备方法 |
| MX2022004558A (es) * | 2019-10-17 | 2023-03-02 | Nova Biomedical Corp | Aparato de ensayo de coagulacion y metodos del mismo. |
| CN116794333A (zh) * | 2022-12-22 | 2023-09-22 | 北京乐普诊断科技股份有限公司 | 一种全面激活血小板基础凝集功能的激活剂配方及其制备方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3518057A (en) * | 1966-04-22 | 1970-06-30 | Huron Road Hospital | Method and apparatus for thrombus formation time determinations |
| US3694161A (en) * | 1971-04-14 | 1972-09-26 | Armour Pharma | Method for measuring platelet aggregation |
| US4051236A (en) * | 1973-02-15 | 1977-09-27 | E. R. Squibb & Sons, Inc. | Inhibition of blood platelet aggregation |
| NO750542L (https=) * | 1974-02-21 | 1975-08-22 | Braun Melsungen Ag | |
| CA1284642C (en) * | 1986-03-31 | 1991-06-04 | Hikozo Iwakura | Prostacyclin (pgi ) analogues |
| US5066592A (en) * | 1988-03-08 | 1991-11-19 | Temple University Of The Commonwealth System Of Higher Education | Trigramin - a platelet aggregation inhibiting polypeptide |
| US5023233A (en) * | 1989-07-28 | 1991-06-11 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| US5242810A (en) * | 1990-12-07 | 1993-09-07 | Biogen, Inc. | Bifunctional inhibitors of thrombin and platelet activation |
| US5763199A (en) * | 1994-09-29 | 1998-06-09 | Mount Sinai School Of Medicine Of The City University Of New York | Platelet blockade assay |
| US6221672B1 (en) * | 1996-04-30 | 2001-04-24 | Medtronic, Inc. | Method for determining platelet inhibitor response |
| US6043871A (en) * | 1997-03-03 | 2000-03-28 | Brigham Young University | System and method for measuring blood platelet function |
| US5922551A (en) * | 1997-03-20 | 1999-07-13 | Accumetrics, Inc. | Agglutrimetric platelet binding assays in blood |
| US6210904B1 (en) * | 1997-10-14 | 2001-04-03 | Merck & Co., Inc. | Anticoagulant test |
| US6063847A (en) * | 1997-11-25 | 2000-05-16 | Schering Corporation | Thrombin receptor antagonists |
| AU2672899A (en) * | 1998-02-27 | 1999-09-15 | Regents Of The University Of California, The | Protease-activated receptor 4 and uses thereof |
| AU6690001A (en) * | 2000-06-15 | 2001-12-24 | Schering Corp | Thrombin receptor antagonists |
| ES2282304T3 (es) * | 2000-11-01 | 2007-10-16 | Astellas Pharma Inc. | Procedimiento para seleccionar antiplaquetas. |
| US6841354B2 (en) * | 2000-12-21 | 2005-01-11 | Philadelphia, Health & Education Corporation | Screening assay for anti-thrombotic/anti-platelet activity |
| EP1394152A4 (en) * | 2001-04-19 | 2005-02-02 | Eisai Co Ltd | 2-IMINOIMIDAZOLE DERIVATIVES (1) |
| US20030148264A1 (en) * | 2001-07-06 | 2003-08-07 | Genentech, Inc. | Phage displayed PDZ domain ligands |
| KR100960170B1 (ko) * | 2001-10-18 | 2010-05-26 | 쉐링 코포레이션 | 트롬빈 수용체 길항제로서의 힘바신 동족체 |
| AU2003277398A1 (en) * | 2002-10-15 | 2004-05-04 | The University Of Tennessee Research Foundation | Methods for assessment of platelet aggregation |
| US20070243632A1 (en) * | 2003-07-08 | 2007-10-18 | Coller Barry S | Methods for measuring platelet reactivity of patients that have received drug eluting stents |
| ATE536889T1 (de) * | 2003-07-08 | 2011-12-15 | Accumetrics Inc | Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten |
| US7595169B2 (en) * | 2005-04-27 | 2009-09-29 | Accumetrics, Inc. | Method for determining percent platelet aggregation |
| WO2007007588A1 (ja) * | 2005-07-08 | 2007-01-18 | Ono Pharmaceutical Co., Ltd. | 平面性を有する環状基を母核とする化合物 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109884326A (zh) * | 2019-03-27 | 2019-06-14 | 深圳优迪生物技术有限公司 | 血小板聚集功能检测试剂盒 |
| CN109884326B (zh) * | 2019-03-27 | 2022-08-19 | 深圳优迪生物技术有限公司 | 血小板聚集功能检测试剂盒 |
Also Published As
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| JP5514101B2 (ja) | 2014-06-04 |
| WO2008137673A1 (en) | 2008-11-13 |
| EP2153235A1 (en) | 2010-02-17 |
| KR20150051243A (ko) | 2015-05-11 |
| KR20100017576A (ko) | 2010-02-16 |
| US20080299587A1 (en) | 2008-12-04 |
| JP2014052388A (ja) | 2014-03-20 |
| JP2010526319A (ja) | 2010-07-29 |
| EP2153235B1 (en) | 2012-05-16 |
| CN101675342A (zh) | 2010-03-17 |
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