JP5514101B2 - トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法 - Google Patents

トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法 Download PDF

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JP5514101B2
JP5514101B2 JP2010507552A JP2010507552A JP5514101B2 JP 5514101 B2 JP5514101 B2 JP 5514101B2 JP 2010507552 A JP2010507552 A JP 2010507552A JP 2010507552 A JP2010507552 A JP 2010507552A JP 5514101 B2 JP5514101 B2 JP 5514101B2
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thrombin
thrombin receptor
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JP2010526319A (ja
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デニス ダービン
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アキュメトリックス インコーポレイテッド
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2010507552A 2007-05-03 2008-05-02 トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法 Active JP5514101B2 (ja)

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Application Number Priority Date Filing Date Title
US91582007P 2007-05-03 2007-05-03
US60/915,820 2007-05-03
PCT/US2008/062415 WO2008137673A1 (en) 2007-05-03 2008-05-02 Methods of measuring inhibition of platelet aggregation by thrombin receptor antagonists

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JP2013251865A Division JP2014052388A (ja) 2007-05-03 2013-12-05 トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法

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JP2010526319A JP2010526319A (ja) 2010-07-29
JP2010526319A5 JP2010526319A5 (https=) 2011-06-23
JP5514101B2 true JP5514101B2 (ja) 2014-06-04

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JP2013251865A Pending JP2014052388A (ja) 2007-05-03 2013-12-05 トロンビンレセプターアンタゴニストによる血小板凝集阻害を測定する方法

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US (1) US20080299587A1 (https=)
EP (1) EP2153235B1 (https=)
JP (2) JP5514101B2 (https=)
KR (2) KR20150051243A (https=)
CN (1) CN101675342A (https=)
ES (1) ES2387700T3 (https=)
WO (1) WO2008137673A1 (https=)

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US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
ATE536889T1 (de) * 2003-07-08 2011-12-15 Accumetrics Inc Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
WO2009152094A2 (en) * 2008-06-09 2009-12-17 Accumetrics, Inc. Hubbed dual cannula device for closed container sampling systems
US8448499B2 (en) 2008-12-23 2013-05-28 C A Casyso Ag Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method
EP2371284A1 (en) * 2010-03-24 2011-10-05 C A Casyso AG Method and apparatus for determining at least one evaluation parameter of a blood sample
WO2011133450A2 (en) 2010-04-19 2011-10-27 Meso Scale Technologies, Llc. Serology assays
JP5999776B2 (ja) * 2010-09-15 2016-09-28 デビオファーマ インターナショナル ソシエテ アノニムＤｅｂｉｏｐｈａｒｍ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｓａ 血液成分を含むフィブリノゲン含有サンプルからターゲット分子又は粒子を分離する方法
RU2559873C2 (ru) * 2011-04-27 2015-08-20 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Миметики поли (adp-рибозы) и способ их получения
CN103969228A (zh) * 2013-02-04 2014-08-06 百奥泰生物科技(广州)有限公司 一种整合素GP IIb/IIIa特异性结合分子巴替非班的生物学效应检测方法
WO2015061733A1 (en) * 2013-10-25 2015-04-30 Bristol-Meyers Squibb Company Diagnostic methods for par4 antagonist therapy
US10816559B2 (en) 2014-09-29 2020-10-27 Ca Casyso Ag Blood testing system and method
US10539579B2 (en) 2014-09-29 2020-01-21 C A Casyso Gmbh Blood testing system and method
CN105717263B (zh) * 2016-03-04 2018-01-26 北京乐普医疗科技有限责任公司 一种检测噻吩并吡啶类抗血小板药物疗效的试剂卡及其使用方法和应用
JP7257333B2 (ja) * 2017-12-28 2023-04-13 株式会社カネカ 細胞凝集抑制剤
CN109884326B (zh) * 2019-03-27 2022-08-19 深圳优迪生物技术有限公司 血小板聚集功能检测试剂盒
CN110051692A (zh) * 2019-04-12 2019-07-26 南京市第一医院 一种血小板定向释放生长因子的组合物及其制备方法
MX2022004558A (es) * 2019-10-17 2023-03-02 Nova Biomedical Corp Aparato de ensayo de coagulacion y metodos del mismo.
CN116794333A (zh) * 2022-12-22 2023-09-22 北京乐普诊断科技股份有限公司 一种全面激活血小板基础凝集功能的激活剂配方及其制备方法

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US3518057A (en) * 1966-04-22 1970-06-30 Huron Road Hospital Method and apparatus for thrombus formation time determinations
US3694161A (en) * 1971-04-14 1972-09-26 Armour Pharma Method for measuring platelet aggregation
US4051236A (en) * 1973-02-15 1977-09-27 E. R. Squibb & Sons, Inc. Inhibition of blood platelet aggregation
NO750542L (https=) * 1974-02-21 1975-08-22 Braun Melsungen Ag
CA1284642C (en) * 1986-03-31 1991-06-04 Hikozo Iwakura Prostacyclin (pgi ) analogues
US5066592A (en) * 1988-03-08 1991-11-19 Temple University Of The Commonwealth System Of Higher Education Trigramin - a platelet aggregation inhibiting polypeptide
US5023233A (en) * 1989-07-28 1991-06-11 Merck & Co., Inc. Fibrinogen receptor antagonists
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
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US20070243632A1 (en) * 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
ATE536889T1 (de) * 2003-07-08 2011-12-15 Accumetrics Inc Kontrollierte thrombozyten-aktivierung zur überwachung der behandlung von adp-antagonisten
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Also Published As

Publication number Publication date
WO2008137673A1 (en) 2008-11-13
EP2153235A1 (en) 2010-02-17
KR20150051243A (ko) 2015-05-11
KR20100017576A (ko) 2010-02-16
US20080299587A1 (en) 2008-12-04
JP2014052388A (ja) 2014-03-20
JP2010526319A (ja) 2010-07-29
EP2153235B1 (en) 2012-05-16
CN101675342A (zh) 2010-03-17
ES2387700T3 (es) 2012-09-28

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