ES2385236B8 - Composición y método para reducir la desmineralización de los dientes. - Google Patents
Composición y método para reducir la desmineralización de los dientes. Download PDFInfo
- Publication number
- ES2385236B8 ES2385236B8 ES201150011A ES201150011A ES2385236B8 ES 2385236 B8 ES2385236 B8 ES 2385236B8 ES 201150011 A ES201150011 A ES 201150011A ES 201150011 A ES201150011 A ES 201150011A ES 2385236 B8 ES2385236 B8 ES 2385236B8
- Authority
- ES
- Spain
- Prior art keywords
- teeth
- composition
- demineralization
- human oral
- reduce
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 238000005115 demineralization Methods 0.000 title abstract 2
- 230000002328 demineralizing effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 2
- OSVXSBDYLRYLIG-UHFFFAOYSA-N dioxidochlorine(.) Chemical compound O=Cl=O OSVXSBDYLRYLIG-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004155 Chlorine dioxide Substances 0.000 abstract 1
- 230000000675 anti-caries Effects 0.000 abstract 1
- 239000001569 carbon dioxide Substances 0.000 abstract 1
- 229910002092 carbon dioxide Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 235000019398 chlorine dioxide Nutrition 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000000214 mouth Anatomy 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 239000002966 varnish Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/16—Fluorine compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B11/00—Oxides or oxyacids of halogens; Salts thereof
- C01B11/02—Oxides of chlorine
- C01B11/022—Chlorine dioxide (ClO2)
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01D—COMPOUNDS OF ALKALI METALS, i.e. LITHIUM, SODIUM, POTASSIUM, RUBIDIUM, CAESIUM, OR FRANCIUM
- C01D3/00—Halides of sodium, potassium or alkali metals in general
- C01D3/02—Fluorides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Materials Engineering (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Dental Preparations (AREA)
- Dentistry (AREA)
Abstract
Una composición para el cuidado bucal humano incluye cantidades seguras y efectivas del ion fluoruro y de dióxido de cloro estabilizado, que puede tomar la forma de una pasta, gel, enjuague, pulverización, polvo, barniz o similar que reduce la desmineralización y promueve la remineralización de los dientes. El método incluye la aplicación tópica de la composición a la cavidad bucal humana (incluyendo, pero sin limitarse a, los dientes, encías, y lengua), preferiblemente al menos una vez al día, para aumentar el efecto anticaries del fluoruro mediante el dióxido de cloro liberado que compromete cualquier biopelícula presente.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14001008P | 2008-12-22 | 2008-12-22 | |
US61/140010 | 2008-12-22 | ||
PCT/US2009/069253 WO2010075419A1 (en) | 2008-12-22 | 2009-12-22 | Composition and method for reducing demineralization of teeth |
Publications (3)
Publication Number | Publication Date |
---|---|
ES2385236A1 ES2385236A1 (es) | 2012-07-20 |
ES2385236B2 ES2385236B2 (es) | 2013-11-26 |
ES2385236B8 true ES2385236B8 (es) | 2014-01-31 |
Family
ID=42288124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES201150011A Expired - Fee Related ES2385236B8 (es) | 2008-12-22 | 2009-12-22 | Composición y método para reducir la desmineralización de los dientes. |
Country Status (11)
Country | Link |
---|---|
US (3) | US20110318282A1 (es) |
EP (1) | EP2370351B1 (es) |
JP (2) | JP5587909B2 (es) |
KR (1) | KR101308920B1 (es) |
CN (1) | CN102264636A (es) |
AU (2) | AU2009329993B2 (es) |
CA (1) | CA2747747C (es) |
ES (1) | ES2385236B8 (es) |
GB (1) | GB2478478C (es) |
MX (1) | MX337445B (es) |
WO (1) | WO2010075419A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100009009A1 (en) | 2008-07-10 | 2010-01-14 | Micropure, Inc. | Method and composition for prevention and treatment of oral fungal infections |
EP2313063A2 (en) | 2008-07-15 | 2011-04-27 | BASF Corporation | Tooth polishing compositions and methods of tooth polishing without mechanical abrasion |
US20100112059A1 (en) | 2008-07-15 | 2010-05-06 | Basf Catalysts Llc | Methods, Systems and Devices for Administration of Chlorine Dioxide |
US8524201B2 (en) | 2008-07-15 | 2013-09-03 | Basf Corporation | Non-cytotoxic chlorine dioxide fluids |
US8311625B2 (en) | 2009-02-04 | 2012-11-13 | Basf Corporation | Chlorine dioxide treatment for biological tissue |
US20100233101A1 (en) | 2009-02-13 | 2010-09-16 | Micropure, Inc. | Composition and method for the oxidative consumption of salivary biomolecules |
GB201202341D0 (en) * | 2012-02-10 | 2012-03-28 | Periproducts Ltd | Multicomponent oral care compostion |
WO2015048146A1 (en) | 2013-09-24 | 2015-04-02 | The Regents Of The University Of Michigan | Compositions and method for destabilizing, altering, and dispersing biofilms |
EP3474951A4 (en) * | 2017-09-01 | 2020-02-19 | Micropure, Inc. | ALIPHATIC ANIONIC COMPOUNDS AND OXIDIZING COMPOUNDS OF IMPROVED STABILITY AND EFFICIENCY FOR USE IN PHARMACEUTICAL COMPOSITIONS |
CA3020197C (en) | 2017-09-01 | 2024-06-04 | Micropure, Inc. | Aliphatic anionic compounds and oxidative compounds with improved stability and efficacy for use in pharmaceutical compositions |
WO2019143746A1 (en) | 2018-01-17 | 2019-07-25 | The Procter & Gamble Company | Methods and compositions to increase the hardness and resistance of enamel |
WO2019160780A1 (en) * | 2018-02-16 | 2019-08-22 | Wang tian xin | Methods and agents to treat tumor cells and cancer |
CN116884616B (zh) * | 2023-08-07 | 2024-02-02 | 南京医科大学附属口腔医院 | 正畸矫治患者脱矿风险预测方法 |
Family Cites Families (38)
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US2451897A (en) | 1946-11-23 | 1948-10-19 | Olin Mathieson | Method of treating shrimp |
US4084747A (en) | 1976-03-26 | 1978-04-18 | Howard Alliger | Germ killing composition and method |
US4330531A (en) | 1976-03-26 | 1982-05-18 | Howard Alliger | Germ-killing materials |
US4793989A (en) | 1984-07-30 | 1988-12-27 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US4689215A (en) | 1984-07-30 | 1987-08-25 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US4886657A (en) | 1984-07-30 | 1989-12-12 | Ratcliff Perry A | Method for preventing periodontitis |
US4975285A (en) | 1984-07-30 | 1990-12-04 | Ratcliff Perry A | Method for cleaning dental prosthetic devices |
US4837009A (en) | 1986-03-31 | 1989-06-06 | Ratcliff Perry A | Method and composition for prevention of plaque formation and plaque dependent diseases |
US4696811A (en) | 1984-07-30 | 1987-09-29 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US4855135A (en) | 1984-07-30 | 1989-08-08 | Ratcliff Perry A | Method for debriding |
US4788053A (en) | 1984-07-30 | 1988-11-29 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US4818519A (en) | 1986-12-29 | 1989-04-04 | Ratcliff Perry A | Method and composition for prevention of plaque formation and plaque dependent diseases |
US4889714A (en) | 1984-07-30 | 1989-12-26 | Ratcliff Perry A | Method for retarding dental plaque by killing streptococcus sanguis |
US4925656A (en) | 1986-03-31 | 1990-05-15 | Ratcliff Perry A | Method for retarding formation of dental plaque |
US4786492A (en) | 1986-03-31 | 1988-11-22 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US4851213A (en) | 1986-03-31 | 1989-07-25 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease due to S. Sanguis |
US4792442A (en) | 1986-03-31 | 1988-12-20 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US5348734A (en) * | 1990-11-20 | 1994-09-20 | Micropure Inc. | Oral health preparation and method |
US5200171A (en) | 1990-11-20 | 1993-04-06 | Micropure, Inc. | Oral health preparation and method |
US4808389A (en) | 1986-12-29 | 1989-02-28 | Ratcliff Perry A | Method and composition for prevention and treatment of oral disease |
US5531982A (en) * | 1987-01-30 | 1996-07-02 | Colgate Palmolive Company | Antimicrobial oral composition |
US4963346A (en) * | 1988-05-31 | 1990-10-16 | Amer & Company, Inc. | Method and composition for treatment or prevention of dental plaque calculus and gingivitis |
US5364462A (en) * | 1991-08-14 | 1994-11-15 | Graphic Utilities, Incorporated | Waterfast inks |
US5489435A (en) | 1993-07-06 | 1996-02-06 | Ratcliff; Perry A. | Composition for treatment of abnormal conditions of the epithelium of bodily orifices |
WO1995027472A1 (en) | 1994-04-07 | 1995-10-19 | Richter Jon L | Oral rinse and method of treating halitosis |
US5753217A (en) * | 1996-08-14 | 1998-05-19 | William C. Christopfel | Method of reducing oral malodor |
DE69836587T2 (de) * | 1997-04-16 | 2007-10-11 | Applera Corp., Foster City | Nukleinsäuresammlung |
US6106293A (en) * | 1998-12-04 | 2000-08-22 | Wiesel; Peter E. | Methods for whitening teeth |
CN1271573A (zh) * | 1999-04-28 | 2000-11-01 | 孙廷柱 | 多功能漱口水 |
US6280775B1 (en) * | 1999-06-09 | 2001-08-28 | Joseph Alan Sasson | Antimicrobial oral composition and method of use |
US7387774B2 (en) | 1999-11-12 | 2008-06-17 | The Procter & Gamble Co. | Method of enhancing fluoridation and mineralization of teeth |
US6582682B2 (en) | 2000-10-30 | 2003-06-24 | Noville, Inc. | Oral care compositions comprising stabilized chlorine dioxide |
US6375933B1 (en) | 2001-01-03 | 2002-04-23 | Colgate Palmolive Company | Dual component dentifrice for reducing mouth odors |
US7216034B2 (en) | 2003-02-27 | 2007-05-08 | Nokia Corporation | System and method for an intelligent multi-modal user interface for route drawing |
US20050084551A1 (en) * | 2003-09-26 | 2005-04-21 | Jensen Claude J. | Morinda citrifolia-based oral care compositions and methods |
US20050234545A1 (en) * | 2004-04-19 | 2005-10-20 | Yea-Yang Su | Amorphous oxide surface film for metallic implantable devices and method for production thereof |
JP2009522330A (ja) * | 2006-01-04 | 2009-06-11 | マウデ ウィクストレム, | 微生物の成長を刺激する口内用健康促進生成物 |
GB201202341D0 (en) * | 2012-02-10 | 2012-03-28 | Periproducts Ltd | Multicomponent oral care compostion |
-
2009
- 2009-12-22 WO PCT/US2009/069253 patent/WO2010075419A1/en active Application Filing
- 2009-12-22 CA CA2747747A patent/CA2747747C/en active Active
- 2009-12-22 GB GB1110765.3A patent/GB2478478C/en active Active
- 2009-12-22 ES ES201150011A patent/ES2385236B8/es not_active Expired - Fee Related
- 2009-12-22 JP JP2011543650A patent/JP5587909B2/ja not_active Expired - Fee Related
- 2009-12-22 MX MX2011006781A patent/MX337445B/es active IP Right Grant
- 2009-12-22 AU AU2009329993A patent/AU2009329993B2/en active Active
- 2009-12-22 KR KR1020117017281A patent/KR101308920B1/ko active IP Right Grant
- 2009-12-22 CN CN200980152183.6A patent/CN102264636A/zh active Pending
- 2009-12-22 EP EP09835778.3A patent/EP2370351B1/en not_active Not-in-force
- 2009-12-22 US US13/131,506 patent/US20110318282A1/en not_active Abandoned
-
2013
- 2013-12-31 US US14/145,426 patent/US20140112875A1/en not_active Abandoned
-
2014
- 2014-07-24 JP JP2014150747A patent/JP5990223B2/ja not_active Expired - Fee Related
-
2016
- 2016-01-07 AU AU2016200101A patent/AU2016200101C1/en active Active
-
2022
- 2022-05-25 US US17/824,816 patent/US20220323318A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP5990223B2 (ja) | 2016-09-07 |
CN102264636A (zh) | 2011-11-30 |
CA2747747C (en) | 2016-02-16 |
GB201110765D0 (en) | 2011-08-10 |
EP2370351B1 (en) | 2016-03-09 |
AU2016200101B2 (en) | 2016-11-24 |
GB2478478C (en) | 2020-03-04 |
US20110318282A1 (en) | 2011-12-29 |
MX337445B (es) | 2016-03-07 |
ES2385236B2 (es) | 2013-11-26 |
AU2016200101A1 (en) | 2016-02-04 |
AU2009329993B2 (en) | 2015-10-08 |
JP2012513476A (ja) | 2012-06-14 |
WO2010075419A1 (en) | 2010-07-01 |
KR101308920B1 (ko) | 2013-09-23 |
JP2014218507A (ja) | 2014-11-20 |
JP5587909B2 (ja) | 2014-09-10 |
AU2016200101C1 (en) | 2017-05-25 |
EP2370351A1 (en) | 2011-10-05 |
US20220323318A1 (en) | 2022-10-13 |
AU2009329993A1 (en) | 2011-07-07 |
MX2011006781A (es) | 2011-12-14 |
GB2478478A (en) | 2011-09-07 |
US20140112875A1 (en) | 2014-04-24 |
KR20110118777A (ko) | 2011-11-01 |
CA2747747A1 (en) | 2010-07-01 |
ES2385236A1 (es) | 2012-07-20 |
EP2370351A4 (en) | 2013-12-25 |
GB2478478B (en) | 2013-05-15 |
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