ES2384057T3 - (E)-N-{3-(8-Cloro-11H-10-oxa-1-aza-dibenzo[a,d]ciclohepten-5-iliden)-propil]-fenil}-metanosulfonamida como modulador del receptor glucocorticoide y procedimientos de uso - Google Patents
(E)-N-{3-(8-Cloro-11H-10-oxa-1-aza-dibenzo[a,d]ciclohepten-5-iliden)-propil]-fenil}-metanosulfonamida como modulador del receptor glucocorticoide y procedimientos de uso Download PDFInfo
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- ES2384057T3 ES2384057T3 ES07799520T ES07799520T ES2384057T3 ES 2384057 T3 ES2384057 T3 ES 2384057T3 ES 07799520 T ES07799520 T ES 07799520T ES 07799520 T ES07799520 T ES 07799520T ES 2384057 T3 ES2384057 T3 ES 2384057T3
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- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83116606P | 2006-07-14 | 2006-07-14 | |
| US831166P | 2006-07-14 | ||
| PCT/US2007/073345 WO2008008882A2 (en) | 2006-07-14 | 2007-07-12 | Glucocorticoid receptor modulator and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2384057T3 true ES2384057T3 (es) | 2012-06-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07799520T Active ES2384057T3 (es) | 2006-07-14 | 2007-07-12 | (E)-N-{3-(8-Cloro-11H-10-oxa-1-aza-dibenzo[a,d]ciclohepten-5-iliden)-propil]-fenil}-metanosulfonamida como modulador del receptor glucocorticoide y procedimientos de uso |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8101760B2 (enExample) |
| EP (1) | EP2043646B1 (enExample) |
| JP (1) | JP5189091B2 (enExample) |
| KR (1) | KR20090020694A (enExample) |
| CN (1) | CN101489556A (enExample) |
| AU (1) | AU2007272504B2 (enExample) |
| BR (1) | BRPI0714811A2 (enExample) |
| CA (1) | CA2655202A1 (enExample) |
| CL (1) | CL2007003501A1 (enExample) |
| EA (1) | EA014695B1 (enExample) |
| ES (1) | ES2384057T3 (enExample) |
| MX (1) | MX2009000583A (enExample) |
| TW (1) | TW200902537A (enExample) |
| WO (1) | WO2008008882A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
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| TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| ES2370148T3 (es) | 2008-01-11 | 2011-12-13 | Eli Lilly & Company | (e)-n-{3-[fluoro-11h-10-oxa-1-aza-dibenzo-[a,d]-ciclohepten-5-iliden)-propil]-fenil}-metilsulfonamida como modulador del receptor de glucocorticoides para el tratamiento de artritis reumatoide. |
| UY31831A (es) | 2008-05-20 | 2010-01-05 | Astrazeneca Ab | Derivados de indazoles sustituidos con fenilo o piridinilo |
| JPWO2010001990A1 (ja) | 2008-07-03 | 2011-12-22 | 協和発酵キリン株式会社 | 四環系化合物 |
| WO2011081173A1 (ja) * | 2009-12-29 | 2011-07-07 | 協和発酵キリン株式会社 | 四環系化合物 |
| CN102746219A (zh) * | 2012-07-02 | 2012-10-24 | 盛世泰科生物医药技术(苏州)有限公司 | 一种2-羧基-3-溴吡啶盐酸盐的合成方法 |
| US10981918B2 (en) | 2018-07-20 | 2021-04-20 | Grünenthal GmbH | Further substituted triazolo quinoxaline derivatives |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3730258A1 (de) | 1986-09-10 | 1988-04-07 | Canon Kk | Elektrophotographisches lichtempfindliches aufzeichnungsmaterial, 5h-dibenzo(a,d)cycloheptanylidenderivat, 5h-dibenzo(a,d)cycloheptenylidenderivat und verfahren zu ihrer herstellung |
| JPH01161245A (ja) | 1987-12-18 | 1989-06-23 | Canon Inc | 電子写真感光体 |
| US4999363A (en) | 1988-06-09 | 1991-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
| US5093210A (en) | 1989-06-30 | 1992-03-03 | Ricoh Company, Ltd. | Electroluminescent device |
| US5378701A (en) | 1991-12-27 | 1995-01-03 | Kyowa Hakko Kogyo | Tricyclic compounds |
| CO4980885A1 (es) | 1997-12-29 | 2000-11-27 | Ortho Mcneil Pharm Inc | Compuestos de trifenilpropanamida utiles en el tratamiento de inflamaciones y metodos para preparar dicho compuesto |
| US7056911B1 (en) | 1999-01-26 | 2006-06-06 | Dana-Farber Cancer Institute | Dibenz[B,F]azepine compounds, pharmaceutical compositions comprising same and methods of use thereof |
| TW200400816A (en) | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
| TWI291467B (en) | 2002-11-13 | 2007-12-21 | Millennium Pharm Inc | CCR1 antagonists and methods of use therefor |
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2007
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- 2007-07-12 AU AU2007272504A patent/AU2007272504B2/en not_active Ceased
- 2007-07-12 MX MX2009000583A patent/MX2009000583A/es active IP Right Grant
- 2007-07-12 BR BRPI0714811-9A2A patent/BRPI0714811A2/pt not_active IP Right Cessation
- 2007-07-12 KR KR1020097000674A patent/KR20090020694A/ko not_active Ceased
- 2007-07-12 US US12/305,295 patent/US8101760B2/en not_active Expired - Fee Related
- 2007-07-12 WO PCT/US2007/073345 patent/WO2008008882A2/en not_active Ceased
- 2007-07-12 CN CNA2007800258079A patent/CN101489556A/zh active Pending
- 2007-07-12 EA EA200970127A patent/EA014695B1/ru not_active IP Right Cessation
- 2007-07-12 ES ES07799520T patent/ES2384057T3/es active Active
- 2007-07-12 CA CA002655202A patent/CA2655202A1/en not_active Abandoned
- 2007-07-12 JP JP2009519689A patent/JP5189091B2/ja not_active Expired - Fee Related
- 2007-12-04 TW TW096146160A patent/TW200902537A/zh unknown
- 2007-12-05 CL CL200703501A patent/CL2007003501A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0714811A2 (pt) | 2014-02-18 |
| EA200970127A1 (ru) | 2009-04-28 |
| CL2007003501A1 (es) | 2008-07-04 |
| EP2043646A2 (en) | 2009-04-08 |
| WO2008008882A2 (en) | 2008-01-17 |
| JP5189091B2 (ja) | 2013-04-24 |
| AU2007272504B2 (en) | 2012-06-28 |
| CN101489556A (zh) | 2009-07-22 |
| TW200902537A (en) | 2009-01-16 |
| US8101760B2 (en) | 2012-01-24 |
| EA014695B1 (ru) | 2010-12-30 |
| JP2009543804A (ja) | 2009-12-10 |
| EP2043646B1 (en) | 2012-05-16 |
| MX2009000583A (es) | 2009-01-27 |
| KR20090020694A (ko) | 2009-02-26 |
| US20100069425A1 (en) | 2010-03-18 |
| WO2008008882A3 (en) | 2008-05-02 |
| CA2655202A1 (en) | 2008-01-17 |
| AU2007272504A1 (en) | 2008-01-17 |
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