ES2372229T3 - Modelos de selección in vivo para el tratamiento de la enfermedad de alzheimer y otros trastornos relacionados con qpct. - Google Patents
Modelos de selección in vivo para el tratamiento de la enfermedad de alzheimer y otros trastornos relacionados con qpct. Download PDFInfo
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- ES2372229T3 ES2372229T3 ES08707977T ES08707977T ES2372229T3 ES 2372229 T3 ES2372229 T3 ES 2372229T3 ES 08707977 T ES08707977 T ES 08707977T ES 08707977 T ES08707977 T ES 08707977T ES 2372229 T3 ES2372229 T3 ES 2372229T3
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US88564907P | 2007-01-19 | 2007-01-19 | |
| US885649P | 2007-01-19 |
Publications (1)
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| ES2372229T3 true ES2372229T3 (es) | 2012-01-17 |
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| EP (2) | EP2121944B1 (enExample) |
| JP (1) | JP2010516235A (enExample) |
| AT (1) | ATE521711T1 (enExample) |
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| US9277737B2 (en) | 2006-09-21 | 2016-03-08 | Probiodrug Ag | Mouse models carrying a knock-out mutation of the QPCTL-gene |
| JP5612860B2 (ja) * | 2007-03-09 | 2014-10-22 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのイミダゾ［１，５−ａ］ピリジン誘導体 |
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| US9034907B2 (en) * | 2007-04-18 | 2015-05-19 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
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| WO2008128987A1 (en) * | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Novel inhibitors |
| JP5676249B2 (ja) * | 2007-04-20 | 2015-02-25 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのアミノピリジン誘導体 |
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| KR101682728B1 (ko) * | 2008-07-31 | 2016-12-05 | 프로비오드룩 아게 | 신경변성 질환에 대한 진단적/예후적 지표로서 글루타미닐 사이클라제 |
| US11219696B2 (en) * | 2008-12-19 | 2022-01-11 | Nationwide Children's Hospital | Delivery of polynucleotides using recombinant AAV9 |
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| EP2879719B1 (en) | 2012-08-01 | 2018-07-04 | Nationwide Children's Hospital | Intrathecal delivery of recombinant adeno-associated virus 9 |
| WO2017079547A2 (en) * | 2015-11-04 | 2017-05-11 | The Scripps Research Institute | Compositions and methods for treating cystic fibrosis |
| MC200185B1 (fr) | 2016-09-16 | 2017-10-04 | Coronal Audio | Dispositif et procédé de captation et traitement d'un champ acoustique tridimensionnel |
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| US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
| DE122007000007I1 (de) | 1986-04-09 | 2007-05-16 | Genzyme Corp | Genetisch transformierte Tiere, die ein gewünschtes Protein in Milch absondern |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5175384A (en) | 1988-12-05 | 1992-12-29 | Genpharm International | Transgenic mice depleted in mature t-cells and methods for making transgenic mice |
| GB8901778D0 (en) | 1989-01-27 | 1989-03-15 | Univ Court Of The University O | Manipulatory technique |
| US5602299A (en) | 1992-09-23 | 1997-02-11 | Mount Sinai School Of Medicine Of The City University Of New York | Transgenic animal models for neurodegenerative disease |
| JPH07132033A (ja) | 1993-11-12 | 1995-05-23 | Hoechst Japan Ltd | アルツハイマー病モデルトランスジェニック動物 |
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| KR101099206B1 (ko) * | 2004-02-05 | 2011-12-27 | 프로비오드룩 아게 | 신규한 글루타미닐 시클라제 저해제 |
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- 2008-01-18 HR HR20110651T patent/HRP20110651T1/hr unknown
- 2008-01-18 CA CA002675192A patent/CA2675192A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2395095A1 (en) | 2011-12-14 |
| ZA200904353B (en) | 2010-09-29 |
| AU2008206936B2 (en) | 2013-03-14 |
| ATE521711T1 (de) | 2011-09-15 |
| AU2008206936A1 (en) | 2008-07-24 |
| CA2675192A1 (en) | 2008-07-24 |
| HRP20110651T1 (hr) | 2011-10-31 |
| JP2010516235A (ja) | 2010-05-20 |
| DK2121944T3 (da) | 2011-10-31 |
| WO2008087197A1 (en) | 2008-07-24 |
| NZ578513A (en) | 2012-01-12 |
| US20080200567A1 (en) | 2008-08-21 |
| EP2121944B1 (en) | 2011-08-24 |
| EP2121944A1 (en) | 2009-11-25 |
| SI2121944T1 (sl) | 2011-12-30 |
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