ES2359125T3 - Procedimiento de preparación de un dispositivo de inyección para administrar en el ojo una sustancia dependiendo de la velocidad y de la temperatura. - Google Patents
Procedimiento de preparación de un dispositivo de inyección para administrar en el ojo una sustancia dependiendo de la velocidad y de la temperatura. Download PDFInfo
- Publication number
- ES2359125T3 ES2359125T3 ES08837661T ES08837661T ES2359125T3 ES 2359125 T3 ES2359125 T3 ES 2359125T3 ES 08837661 T ES08837661 T ES 08837661T ES 08837661 T ES08837661 T ES 08837661T ES 2359125 T3 ES2359125 T3 ES 2359125T3
- Authority
- ES
- Spain
- Prior art keywords
- mixture
- dispensing chamber
- housing
- eye
- needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000002347 injection Methods 0.000 title claims abstract description 51
- 239000007924 injection Substances 0.000 title claims abstract description 51
- 238000000034 method Methods 0.000 title claims abstract description 18
- 239000000126 substance Substances 0.000 title description 44
- 239000003814 drug Substances 0.000 claims abstract description 51
- 229940079593 drug Drugs 0.000 claims abstract description 51
- 239000000203 mixture Substances 0.000 claims abstract description 41
- 239000007788 liquid Substances 0.000 claims abstract description 18
- 238000010438 heat treatment Methods 0.000 claims description 5
- 239000000825 pharmaceutical preparation Substances 0.000 claims description 3
- 229940127557 pharmaceutical product Drugs 0.000 claims description 3
- 150000002634 lipophilic molecules Chemical class 0.000 claims description 2
- 239000006187 pill Substances 0.000 description 28
- 150000001875 compounds Chemical class 0.000 description 26
- 230000007704 transition Effects 0.000 description 18
- 239000012530 fluid Substances 0.000 description 10
- 239000007787 solid Substances 0.000 description 8
- 230000007246 mechanism Effects 0.000 description 7
- 238000001879 gelation Methods 0.000 description 5
- 238000001816 cooling Methods 0.000 description 4
- 230000006870 function Effects 0.000 description 4
- 238000007789 sealing Methods 0.000 description 4
- 238000000151 deposition Methods 0.000 description 3
- 238000012377 drug delivery Methods 0.000 description 3
- 230000003628 erosive effect Effects 0.000 description 3
- 208000005590 Choroidal Neovascularization Diseases 0.000 description 2
- 206010060823 Choroidal neovascularisation Diseases 0.000 description 2
- 206010048843 Cytomegalovirus chorioretinitis Diseases 0.000 description 2
- 206010064930 age-related macular degeneration Diseases 0.000 description 2
- 239000005441 aurora Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 208000001763 cytomegalovirus retinitis Diseases 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- FETSQPAGYOVAQU-UHFFFAOYSA-N glyceryl palmitostearate Chemical compound OCC(O)CO.CCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O FETSQPAGYOVAQU-UHFFFAOYSA-N 0.000 description 2
- 239000004973 liquid crystal related substance Substances 0.000 description 2
- 208000002780 macular degeneration Diseases 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- YZDHIUAERJBOIP-UHFFFAOYSA-N C(CCC12)CC1C1C2C=C=CC1 Chemical compound C(CCC12)CC1C1C2C=C=CC1 YZDHIUAERJBOIP-UHFFFAOYSA-N 0.000 description 1
- 206010012689 Diabetic retinopathy Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
- 208000001344 Macular Edema Diseases 0.000 description 1
- 206010025415 Macular oedema Diseases 0.000 description 1
- 208000002367 Retinal Perforations Diseases 0.000 description 1
- 206010038897 Retinal tear Diseases 0.000 description 1
- 206010038910 Retinitis Diseases 0.000 description 1
- 206010038923 Retinopathy Diseases 0.000 description 1
- 241000220010 Rhode Species 0.000 description 1
- 206010046851 Uveitis Diseases 0.000 description 1
- 208000036866 Vitreoretinopathy Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000001647 drug administration Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 229910052744 lithium Inorganic materials 0.000 description 1
- 201000010230 macular retinal edema Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 201000001119 neuropathy Diseases 0.000 description 1
- 230000007823 neuropathy Effects 0.000 description 1
- 230000006785 proliferative vitreoretinopathy Effects 0.000 description 1
- 238000010992 reflux Methods 0.000 description 1
- 230000008439 repair process Effects 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- TXEYQDLBPFQVAA-UHFFFAOYSA-N tetrafluoromethane Chemical compound FC(F)(F)F TXEYQDLBPFQVAA-UHFFFAOYSA-N 0.000 description 1
- -1 these Chemical class 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
- A61M5/445—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media the media being heated in the reservoir, e.g. warming bloodbags
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/36—General characteristics of the apparatus related to heating or cooling
- A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14566—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons with a replaceable reservoir for receiving a piston rod of the pump
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97845807P | 2007-10-09 | 2007-10-09 | |
| US978458P | 2007-10-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2359125T3 true ES2359125T3 (es) | 2011-05-18 |
Family
ID=40091362
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES08837661T Active ES2359125T3 (es) | 2007-10-09 | 2008-10-01 | Procedimiento de preparación de un dispositivo de inyección para administrar en el ojo una sustancia dependiendo de la velocidad y de la temperatura. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20090093789A1 (enExample) |
| EP (1) | EP2187849B1 (enExample) |
| JP (1) | JP5302320B2 (enExample) |
| AR (1) | AR068720A1 (enExample) |
| AT (1) | ATE498379T1 (enExample) |
| AU (1) | AU2008311080B2 (enExample) |
| CA (1) | CA2698155C (enExample) |
| DE (1) | DE602008005037D1 (enExample) |
| ES (1) | ES2359125T3 (enExample) |
| TW (1) | TWI498136B (enExample) |
| WO (1) | WO2009048782A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8372036B2 (en) * | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
| US8177747B2 (en) * | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
| US10213533B2 (en) * | 2012-03-05 | 2019-02-26 | Keith A. Walter | Medical tools with aspiration tips suitable for cataract surgeries and related methods |
| US10220186B2 (en) | 2012-05-23 | 2019-03-05 | Becton, Dickinson And Company | Collapse-resistant swellable catheter |
Family Cites Families (96)
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| US2591457A (en) * | 1948-09-15 | 1952-04-01 | Emma C Maynes | Syringe operating device |
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| US3089815A (en) * | 1951-10-11 | 1963-05-14 | Lieb Hans | Injectable pharmaceutical preparation, and a method of making same |
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| BE548210A (enExample) * | 1955-01-14 | |||
| DK93503C (da) * | 1961-04-27 | 1962-05-21 | Leo Pharm Prod Ltd | Dobbelttube bestående af et tubelegeme og et om tubelegemet passende tubehylster. |
| US3199740A (en) * | 1963-08-07 | 1965-08-10 | Bayer Ag | Ejection device |
| US3311265A (en) * | 1965-06-03 | 1967-03-28 | Chem Dev Corp | Double-barreled dispensing gun |
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| US3439675A (en) * | 1966-06-14 | 1969-04-22 | Becton Dickinson Co | Deformable needle assembly |
| US3608549A (en) * | 1970-01-15 | 1971-09-28 | Merrill Edward Wilson | Method of administering drugs and capsule therefor |
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-
2008
- 2008-09-30 TW TW097137478A patent/TWI498136B/zh not_active IP Right Cessation
- 2008-10-01 JP JP2010528948A patent/JP5302320B2/ja not_active Expired - Fee Related
- 2008-10-01 AT AT08837661T patent/ATE498379T1/de not_active IP Right Cessation
- 2008-10-01 EP EP08837661A patent/EP2187849B1/en not_active Not-in-force
- 2008-10-01 ES ES08837661T patent/ES2359125T3/es active Active
- 2008-10-01 AU AU2008311080A patent/AU2008311080B2/en not_active Ceased
- 2008-10-01 CA CA2698155A patent/CA2698155C/en not_active Expired - Fee Related
- 2008-10-01 US US12/243,729 patent/US20090093789A1/en not_active Abandoned
- 2008-10-01 DE DE602008005037T patent/DE602008005037D1/de active Active
- 2008-10-01 WO PCT/US2008/078490 patent/WO2009048782A2/en not_active Ceased
- 2008-10-02 AR ARP080104315A patent/AR068720A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008311080B2 (en) | 2013-03-21 |
| WO2009048782A2 (en) | 2009-04-16 |
| JP2011500155A (ja) | 2011-01-06 |
| TW200924813A (en) | 2009-06-16 |
| ATE498379T1 (de) | 2011-03-15 |
| DE602008005037D1 (de) | 2011-03-31 |
| AR068720A1 (es) | 2009-12-02 |
| EP2187849A2 (en) | 2010-05-26 |
| EP2187849B1 (en) | 2011-02-16 |
| AU2008311080A1 (en) | 2009-04-16 |
| CA2698155A1 (en) | 2009-04-16 |
| JP5302320B2 (ja) | 2013-10-02 |
| TWI498136B (zh) | 2015-09-01 |
| US20090093789A1 (en) | 2009-04-09 |
| CA2698155C (en) | 2016-03-29 |
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