ES2343010T3 - Proceso para preparacion de l-aminoacidos que utiliza cepas de la familia enterobacteriaceas. - Google Patents
Proceso para preparacion de l-aminoacidos que utiliza cepas de la familia enterobacteriaceas. Download PDFInfo
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- ES2343010T3 ES2343010T3 ES04803729T ES04803729T ES2343010T3 ES 2343010 T3 ES2343010 T3 ES 2343010T3 ES 04803729 T ES04803729 T ES 04803729T ES 04803729 T ES04803729 T ES 04803729T ES 2343010 T3 ES2343010 T3 ES 2343010T3
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- 235000005985 organic acids Nutrition 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 101150035909 pepB gene Proteins 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 229940066779 peptones Drugs 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 229960005190 phenylalanine Drugs 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- DTBNBXWJWCWCIK-UHFFFAOYSA-K phosphonatoenolpyruvate Chemical compound [O-]C(=O)C(=C)OP([O-])([O-])=O DTBNBXWJWCWCIK-UHFFFAOYSA-K 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920001522 polyglycol ester Polymers 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 230000003823 potassium efflux Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000013587 production medium Substances 0.000 description 1
- 229960002429 proline Drugs 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 150000003212 purines Chemical class 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007670 refining Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- JQXXHWHPUNPDRT-WLSIYKJHSA-N rifampicin Chemical compound O([C@](C1=O)(C)O/C=C/[C@@H]([C@H]([C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(C)/C(=O)NC=2C(O)=C3C([O-])=C4C)C)OC)C4=C1C3=C(O)C=2\C=N\N1CC[NH+](C)CC1 JQXXHWHPUNPDRT-WLSIYKJHSA-N 0.000 description 1
- 229960001225 rifampicin Drugs 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000002600 sunflower oil Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 150000003628 tricarboxylic acids Chemical class 0.000 description 1
- 229960004799 tryptophan Drugs 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 150000003680 valines Chemical class 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/185—Escherichia
- C12R2001/19—Escherichia coli
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10361268 | 2003-12-24 | ||
| DE10361268A DE10361268A1 (de) | 2003-12-24 | 2003-12-24 | Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2343010T3 true ES2343010T3 (es) | 2010-07-21 |
Family
ID=34706593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES04803729T Expired - Lifetime ES2343010T3 (es) | 2003-12-24 | 2004-12-10 | Proceso para preparacion de l-aminoacidos que utiliza cepas de la familia enterobacteriaceas. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1697530B1 (pl) |
| CN (1) | CN1898392B (pl) |
| AT (1) | ATE462798T1 (pl) |
| DE (2) | DE10361268A1 (pl) |
| DK (1) | DK1697530T3 (pl) |
| ES (1) | ES2343010T3 (pl) |
| PL (1) | PL1697530T3 (pl) |
| WO (1) | WO2005064000A1 (pl) |
| ZA (1) | ZA200605220B (pl) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007185184A (ja) * | 2005-12-16 | 2007-07-26 | Ajinomoto Co Inc | Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造法 |
| IN2014MN01298A (pl) * | 2011-12-21 | 2015-07-03 | Cj Cheiljedang Corp | |
| KR101500073B1 (ko) | 2013-04-23 | 2015-03-06 | 씨제이제일제당 (주) | L-아르기닌 생산능이 향상된 코리네박테리움속 미생물 및 이를 이용한 l-아르기닌의 생산 방법 |
| CN104630300B (zh) * | 2013-11-13 | 2018-06-22 | 中国科学院上海生命科学研究院 | 一种l-氨基酸生产方法 |
| CN104845995B (zh) * | 2014-02-14 | 2018-11-13 | 中国科学院微生物研究所 | 一种动态调控苏氨酸外排转运蛋白基因表达生产l-苏氨酸的方法 |
| CN109852572B (zh) * | 2019-01-28 | 2021-05-28 | 江南大学 | 一种敲除大肠杆菌pts系统提高l-苏氨酸产量的方法 |
| CN111440797B (zh) * | 2020-04-10 | 2021-10-22 | 江南大学 | 诱导型启动子的获得及其应用 |
| CN111471638B (zh) * | 2020-05-22 | 2021-11-23 | 江南大学 | 一株产l-高丝氨酸的谷氨酸棒杆菌突变株的构建与应用 |
| CN112391331B (zh) * | 2020-11-12 | 2022-09-27 | 江南大学 | 一种过表达GatA基因的重组大肠杆菌及其应用 |
| KR20240152455A (ko) * | 2023-04-12 | 2024-10-22 | 씨제이제일제당 (주) | 피루브산 탈수소효소 복합체 디히드로리포일리신-잔기 아세틸트랜스퍼라제의 활성이 증가된 미생물 및 이를 이용한 l-아미노산 생산 방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5685289A (en) | 1979-12-13 | 1981-07-11 | Ajinomoto Co Inc | Preparation of l-valine by fermentation |
| WO2003008602A2 (en) * | 2001-07-18 | 2003-01-30 | Degussa Ag | Process for the preparation of l-amino acids using strains of the enterobacteriaceae family which contain an attenuated ugpb gene |
| EP1483392B1 (en) * | 2002-03-13 | 2010-12-01 | Evonik Degussa GmbH | Process for the preparation of l-amino acids using strains of the family enterobacteriaceae |
-
2003
- 2003-12-24 DE DE10361268A patent/DE10361268A1/de not_active Withdrawn
-
2004
- 2004-12-10 WO PCT/EP2004/014082 patent/WO2005064000A1/en not_active Ceased
- 2004-12-10 ES ES04803729T patent/ES2343010T3/es not_active Expired - Lifetime
- 2004-12-10 EP EP04803729A patent/EP1697530B1/en not_active Expired - Lifetime
- 2004-12-10 DK DK04803729.5T patent/DK1697530T3/da active
- 2004-12-10 AT AT04803729T patent/ATE462798T1/de active
- 2004-12-10 CN CN2004800388079A patent/CN1898392B/zh not_active Expired - Fee Related
- 2004-12-10 DE DE602004026351T patent/DE602004026351D1/de not_active Expired - Lifetime
- 2004-12-10 PL PL04803729T patent/PL1697530T3/pl unknown
-
2006
- 2006-06-23 ZA ZA2006/05220A patent/ZA200605220B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200605220B (en) | 2007-10-31 |
| EP1697530A1 (en) | 2006-09-06 |
| ATE462798T1 (de) | 2010-04-15 |
| PL1697530T3 (pl) | 2010-08-31 |
| DK1697530T3 (da) | 2010-07-12 |
| WO2005064000A1 (en) | 2005-07-14 |
| CN1898392A (zh) | 2007-01-17 |
| DE10361268A1 (de) | 2005-07-28 |
| CN1898392B (zh) | 2010-06-09 |
| EP1697530B1 (en) | 2010-03-31 |
| DE602004026351D1 (de) | 2010-05-12 |
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