ES2337537B2 - PREPARED FOOD AND PHARMACEUTICAL COMPOSITION CONTAINING AN EMBRYO EXTRACT AND ITS RESPECTIVE USES. - Google Patents

Abstract

Food preparation and pharmaceutical composition that
It contains an embryonic extract and its respective uses. The food preparation comprises an embryonic germ in the final phase of the gastrula extracted from a fertilized and incubated egg. On the other hand, the pharmaceutical composition contains as an active substance an embryonic extract at the stage of final embryonic development of the gland extracted from a fertilized and incubated egg. Said preparation is used as a food supplement for the prevention of hair loss. On the other hand, said pharmaceutical composition can be used as a medicament for antidegenerative treatments.

Description

Food preparation and pharmaceutical composition It contains an embryonic extract and its respective uses.

Technical sector of the invention

Food preparation and pharmaceutical composition It contains an embryonic extract and its respective uses.

Background of the invention

It is known that during the period of cellular organogenesis, certain regulatory substances prevent unlimited multiplication of cells typical of the development of certain diseases, such as cancer.

This fact has motivated them to be carried out. experiments to determine the effects of embryonic tissues homogenized in the growth and spread of tumors.

Following this line of research, they have released preparations for prevention and treatment of cancer whose active substance are embryonic extracts taken in specific stages of embryonic development.

As an example, CA documents stand out 2197050 and WO 9811905 describing respective preparations that they contain fertilized chicken egg extracts, which have been preferably incubated between about 8 and approximately 10 days, and embryonic egg extracts from trout, in a development stage of 5 to 20 somites.

Explanation of the invention.

The applicant has been able to verify that the administration of embryo extracts taken at one stage prior to the extraction stages to date used, and very specific to embryonic development, it has effects surprisingly revitalizers predictably related to a significant effect on the rhythm of cell divisions.

For this, the embryonic germ must be obtained prior to the formation of segmented tissue masses mesodermal, or somites, in embryonic development, but once the blastula phase completed. Specifically, the embryonic germ is obtained in the food preparation of the invention when they have been developed the three embryonic leaves ectoblasto-mesoblasto-entoblasto in an egg fertilized and incubated during a specific period, with that the food preparation comprises at least one germ embryonic in the final phase of the gastrula.

According to another characteristic of the preparation according to the invention, the embryonic germ is extracted from a chicken egg during the period between 18 and 30 hours after incubation.

According to a variant of obtaining, the prepared also includes part of the egg yolk aspirated during the extraction of the germ by aspiration.

Preferably, the preparation is frozen for conservation and subsequent oral administration.

Administration of the preparation in humans is indicated as regenerative in case of dry skin or fall of hairs

The administration of the preparation in animals is indicated as vitalizer and stimulant of defenses in case of suffer from infectious or parasitic diseases such as Leishmaniasis in dogs or viral immunodeficiencies in cats.

According to another aspect of the invention, it is given to know a pharmaceutical composition that contains as a substance activate at least one embryonic extract in the development stage embryonic end of gastrula extracted from a fertilized egg e incubated

The composition is intended for use in antidegenerative treatments, to treat osteoarthritis, cirrhosis, Nephritis or neurodegenerative processes.

The composition is also intended for use in regenerative treatments in mammals.

According to another application, the composition is intended for use as an adjunct to treatments against cancer, such as radiotherapy and chemotherapy.

Detailed description of the invention

An example of obtaining at least one embryonic germ for the preparation food according to the invention.

A fertilized chicken egg is extracted from a incubator after a period between 18 and 36 hours after incubation. Thus an embryonic germ is achieved in the final phase of the gastrula, prior to the formation of somites. He content obtained after the breakage of the shell, formed by the yolk and the clear one, is deposited later in a sterile tray.

Next, the yolk is shaken by balancing the tray until the embryonic germ is placed in a position Dorsal and centered. In this position, the aspiration of said embryonic germ that is contained along with the yolk surrounding in an amount of volume approximately between 0.5 and 2 ml, according to the aspiration performed. For the mentioned aspiration, use, in a manner known per se, a sterile syringe, plunger or pipette.

Prior to administration, proceed to your freezing for storage and at the time of use has to be defrosted Even so, it can be administered directly without the freezing process

After said explanation of obtaining of this preparation several practical examples will be explained with different users, first two cases are explained in animals and then two other cases in human patients.

In a male and European feline patient of 16 years old and with 4 kg of weight that was suffering from anorexia, cachexia, chronic nephritis and generalized pain, a treatment based on the preparation according to the invention. It was administered a dose of 1 ml of daily extract. After two weeks he recovered his appetite, the pain disappearing and all normalized the vital signs and gaining weight up to the current 5.5 kg after three years of initiation of treatment. In this case, the life expectancy of said patient exceeds the average of the more than 20%

In another patient, in this case a dog of breed 9-year-old male boxer who was affected by leishmaniosis and malignant tumors, in addition to subjecting the patient to an operation and to a leishmaniasis treatment with the relevant medication, you will be applied a dose of egg extract according to the invention at the rate of 2 ml twice a day. Today, after three years, it has not presented recurrences of the tumors and has overcome leishmaniosis, being its optimum quality of life.

In a human patient, a 41-year-old male, who I was affected by baldness, prostatitis, tiredness, cholesterolemia, tachycardia and arterial hypertension, a treatment based on of the preparation according to the invention. A dose of 2 ml was administered three times a day, beginning to observe at six months of onset of follicle growth treatment, symptom normalization prosthetics, normalization of heart rate and blood pressure. After 5 years it can be seen that the quality has been improved of life of said patient.

In another human patient, in this case a woman 39, affected by cancer with several metastases for several years nine years, in chemotherapy and radiotherapy treatment, began to administer the treatment at a rate of 2 ml with nine doses daily. It is carried out by applying said treatment in said patient for five months and a substantial improvement in the quality of life, increasing fatigue resistance, increasing Vitability and physical capacity.

After these described examples, it has been conducted a global sample to study the results. In bliss study sample comprised of animals, 15 dogs and 2 cats, and eight humans, it has been concluded that there are no effects pernicious or secondary. Specifically, they are exposed below The results obtained.

At the animal level:

In three of the dogs in the sample, affected of leishmaniasis, an increase of regenerative capacity in the bone marrow, red blood cells and whites. In general, it improves the quality of life, bringing a dog with nephritis heals and overcomes insufficiency renal.

In three other dogs in the sample, affected by hepatitis, it is observed that they overcome the disease without leaving aftermath.

In another of the dogs, affected by hypothyroidism, with the administration of said egg extract, you allows you to reduce the dose of thyroxine in half as the Gland is activating.

In five of the dogs, affected by osteoarthritis and a cachectic state, your mood is improved and your hope of life, surpassing it by 20%.

In three of the dogs in the sample, affected of cancer, your quality of life is improved without weight loss, Increasing your life expectancy.

In a cat of the sample, affected by nephritis, the disease is stabilized and your hope is increased of life, surpassing it by 30%.

In the other cat in the sample, affected by encephalitis with daily epilepsy attacks, after treatment with egg extract attacks are reduced until values of only one attack per month.

At the human level:

In one of the human patients in the sample, affected by fatigue, limb pain and progressive baldness, post-treatment is observed the disappearance of all fatigue symptoms and follicular growth occurs in the patient.

In another 70-year-old female patient, affected by allergy, gastric pain and hair loss, it is observed a disappearance of all symptoms and an improvement of the state General of the patient.

In another human patient, affected by cancer pulmonary and metastasis with chemotherapy treatment, it is observed, after treatment, a general improvement that produces a greater vitality of the individual.

In another patient, affected by a fracture of unconsolidated femur that has caused loss of muscle mass and resistance to movement, an improvement in movement and A muscular strength increase.

In a patient, affected by an inflammation of the intestinal mucosa that produces abdominal pain, it is observed that Symptoms improve with such treatment.

In three other patients over 60 years old, with tiredness, it is observed that the symptoms of tiredness improve and Increases the vital tone.

Notably, it is worth mentioning that with the administration of said preparation in this type of treatment is not has detected any side effects, demonstrating in more than Two hundred patients their safety.

Claims (11)

1. Food preparation comprising at least an embryonic germ in the final phase of the gastrula extracted from an egg fertilized and incubated. 2. Prepared according to claim 1, characterized in that the embryonic germ is extracted from a chicken egg during the period between 18 and 30 hours after incubation. 3. Prepared according to claims 1 or 2, characterized in that it further comprises part of the egg yolk, which is aspirated during extraction of the germ by aspiration. 4. Prepared according to any one of the preceding claims, characterized in that it is frozen for preservation and subsequent oral administration. 5. Use of a preparation according to any one of claims 1 to 4, for the preparation of a complement food for the prevention of dry skin. 6. Use of a preparation according to any one of claims 1 to 4, for the preparation of a complement Food for the prevention of hair loss. 7. Use of a preparation according to any one of claims 1 to 4, for the preparation of a stimulant of the defenses indicated to fight infectious diseases or parasitic in dogs and cats. 8. Pharmaceutical composition containing as active substance at least one embryonic extract in the stage of embryonic development of the end of the gastrula extracted from an egg fertilized and incubated. 9. Use of a composition according to claim 8 for the preparation of a medicament for antidegenerative treatments. 10. Use of a composition according to claim 8 for the preparation of a medicament for regenerative treatments in mammals. 11. Use of a composition according to claim 8 to obtain a food supplement for use as an adjunct to cancer treatments, such as radiotherapy and chemotherapy.