ES2313788T3 - Modulo y procedimiento para introducir una muestra en una columna de cromatografia. - Google Patents

Modulo y procedimiento para introducir una muestra en una columna de cromatografia. Download PDF

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Publication number
ES2313788T3
ES2313788T3 ES99934054T ES99934054T ES2313788T3 ES 2313788 T3 ES2313788 T3 ES 2313788T3 ES 99934054 T ES99934054 T ES 99934054T ES 99934054 T ES99934054 T ES 99934054T ES 2313788 T3 ES2313788 T3 ES 2313788T3
Authority
ES
Spain
Prior art keywords
chromatography
column
sample
sealing
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99934054T
Other languages
English (en)
Spanish (es)
Inventor
Ivan Hargro
Jeffrey A. Horsman
Peter C. Rahn
Peter C. Vandavelaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotage AB
Original Assignee
Biotage AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22476620&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2313788(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biotage AB filed Critical Biotage AB
Application granted granted Critical
Publication of ES2313788T3 publication Critical patent/ES2313788T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6026—Fluid seals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N2030/167—Injection on-column injection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/522—Physical parameters pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6021—Adjustable pistons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6069—Construction of the column body with compartments or bed substructure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Sampling And Sample Adjustment (AREA)
ES99934054T 1998-08-20 1999-07-14 Modulo y procedimiento para introducir una muestra en una columna de cromatografia. Expired - Lifetime ES2313788T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US137278 1987-12-23
US09/137,278 US6139733A (en) 1998-08-20 1998-08-20 Module and method for introducing a sample into a chromatography column

Publications (1)

Publication Number Publication Date
ES2313788T3 true ES2313788T3 (es) 2009-03-01

Family

ID=22476620

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99934054T Expired - Lifetime ES2313788T3 (es) 1998-08-20 1999-07-14 Modulo y procedimiento para introducir una muestra en una columna de cromatografia.

Country Status (8)

Country Link
US (3) US6139733A (enExample)
EP (1) EP1113849B1 (enExample)
JP (1) JP4328898B2 (enExample)
AT (1) ATE406947T1 (enExample)
AU (1) AU4997399A (enExample)
DE (1) DE69939479D1 (enExample)
ES (1) ES2313788T3 (enExample)
WO (1) WO2000010676A1 (enExample)

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US20030217973A1 (en) * 1998-08-20 2003-11-27 Horsman Jeffrey A. Method for introducing a sample into a chromatography column
US6679989B2 (en) * 2001-06-01 2004-01-20 Agilent Technologies, Inc. Integral, thru-bore, direct coupled high pressure liquid chromatography guard column
US6880576B2 (en) 2001-06-07 2005-04-19 Nanostream, Inc. Microfluidic devices for methods development
US20020187557A1 (en) * 2001-06-07 2002-12-12 Hobbs Steven E. Systems and methods for introducing samples into microfluidic devices
US7261812B1 (en) 2002-02-13 2007-08-28 Nanostream, Inc. Multi-column separation devices and methods
AU2003213071A1 (en) * 2002-02-13 2003-09-04 Nanostream, Inc. Microfluidic separation column devices and fabrication methods
US6649051B1 (en) 2002-05-01 2003-11-18 Biotage, Inc. Processing of chemicals in flow-through device with porous media
US20030205456A1 (en) * 2002-05-01 2003-11-06 Jamalabadi Shahnaz Ghassemi Processing of chemicals in flow-through device with porous media
KR100505361B1 (ko) * 2002-06-03 2005-08-03 정원조 소결 무기 분말 프릿이 장착된 금속 튜빙/프릿 및 이를이용하여 제작하는 크로마토그래피 컬럼
US20040142488A1 (en) * 2002-07-15 2004-07-22 Gierde Douglas T. Method and device for extracting an analyte
EP1521637B1 (en) * 2002-07-15 2011-10-19 Phynexus, Inc. Extraction column device
US6783673B2 (en) * 2002-08-23 2004-08-31 Biotage, Inc. Composite chromatography column
JP4909513B2 (ja) 2002-09-10 2012-04-04 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフカラムおよび吸収剤密度を制御するための方法
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
AU2003298894A1 (en) * 2002-11-26 2004-06-18 Prime Separations, Incorporated Chromatographic separation processes and apparatus
WO2004058379A1 (en) * 2002-12-17 2004-07-15 Biotage,Inc. Processing of chemicals in flow-through device porous media
JP4791352B2 (ja) * 2003-02-07 2011-10-12 ウオーターズ・テクノロジーズ・コーポレイシヨン クロマトグラフィーナノカラム用ポリマー固体支持体
DE112004000244T5 (de) * 2003-02-10 2006-02-09 Waters Investments Ltd., New Castle Siloxan-immobilisierte partikuläre stationäre Phasen für chromatographische Auftrennungen und Extraktionen
WO2005007264A2 (en) * 2003-07-14 2005-01-27 Waters Investments Limited Separation device with integral guard column
US7943393B2 (en) * 2003-07-14 2011-05-17 Phynexus, Inc. Method and device for extracting an analyte
US20050011821A1 (en) * 2003-07-17 2005-01-20 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US20050011835A1 (en) * 2003-07-17 2005-01-20 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US20050211617A1 (en) * 2003-07-17 2005-09-29 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US20050032238A1 (en) * 2003-08-07 2005-02-10 Nanostream, Inc. Vented microfluidic separation devices and methods
US7028536B2 (en) * 2004-06-29 2006-04-18 Nanostream, Inc. Sealing interface for microfluidic device
US7404893B2 (en) * 2003-10-17 2008-07-29 Varian, Inc. Chromatography cartridge and method for manufacturing a chromatography cartridge
US7351332B2 (en) * 2003-10-17 2008-04-01 Varian, Inc. Chromatography cartridge and method for manufacturing a chromatography cartridge
US7686959B2 (en) 2004-05-05 2010-03-30 Biotage Ab Control system and method for flash separation
US20050247625A1 (en) * 2004-05-05 2005-11-10 Jianbo Liu Determining conditions for chromatography
US7138061B2 (en) * 2004-05-10 2006-11-21 Scientific Plastic Products, Inc. Flash chromatography cartridge
GB2467031B8 (en) * 2004-08-19 2010-12-22 Waters Investments Ltd Analytical column for use in hplc separations.
US7348526B2 (en) * 2004-08-20 2008-03-25 Cem Corporation Microwave-assisted chromatography preparation
US7674383B2 (en) * 2005-10-25 2010-03-09 Phenomenex, Inc. Method and apparatus for packing chromatography columns
US7670487B2 (en) * 2006-07-21 2010-03-02 Wikfors Edwin E De-pressurization scheme for chromatography columns
CN103630639A (zh) 2007-12-05 2014-03-12 全技术联合公司 用于分析样本和收集样本流份的方法和装置
CN102307665A (zh) 2008-12-04 2012-01-04 全技术联合公司 用于移动等分流体试样的方法和设备
JP2012511725A (ja) 2008-12-10 2012-05-24 オールテック・アソシエイツ・インコーポレーテッド クロマトグラフィーシステムおよびシステム部品
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JP5879592B2 (ja) * 2011-12-26 2016-03-08 東京理化器械株式会社 カラム

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Also Published As

Publication number Publication date
DE69939479D1 (de) 2008-10-16
JP2002523728A (ja) 2002-07-30
AU4997399A (en) 2000-03-14
EP1113849A1 (en) 2001-07-11
WO2000010676A1 (en) 2000-03-02
US6139733A (en) 2000-10-31
EP1113849B1 (en) 2008-09-03
JP4328898B2 (ja) 2009-09-09
ATE406947T1 (de) 2008-09-15
EP1113849A4 (en) 2001-10-17
US6294087B1 (en) 2001-09-25
US6221252B1 (en) 2001-04-24

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