ES2311803T3 - Composiciones embolicas de silicie pirogena. - Google Patents
Composiciones embolicas de silicie pirogena. Download PDFInfo
- Publication number
- ES2311803T3 ES2311803T3 ES04715148T ES04715148T ES2311803T3 ES 2311803 T3 ES2311803 T3 ES 2311803T3 ES 04715148 T ES04715148 T ES 04715148T ES 04715148 T ES04715148 T ES 04715148T ES 2311803 T3 ES2311803 T3 ES 2311803T3
- Authority
- ES
- Spain
- Prior art keywords
- pirogena
- silicon
- embolic compositions
- sterilization
- embolic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000203 mixture Substances 0.000 title abstract 4
- 230000003073 embolic effect Effects 0.000 title abstract 2
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical group [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 title 1
- 229910052710 silicon Inorganic materials 0.000 title 1
- 239000010703 silicon Substances 0.000 title 1
- 230000001954 sterilising effect Effects 0.000 abstract 3
- 238000004659 sterilization and disinfection Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
- A61L24/0089—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/128—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/18—Materials at least partially X-ray or laser opaque
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/36—Materials or treatment for tissue regeneration for embolization or occlusion, e.g. vaso-occlusive compositions or devices
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Composite Materials (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Treatment And Processing Of Natural Fur Or Leather (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición que comprende: (1) un polímero biocompatible insoluble en sangre u otro fluido corporal, (2) un disolvente biocompatible que es capaz de solubilizar el polímero biocompatible y es miscible en sangre u otro fluido corporal, (3) un agente de contraste biocompatible, y (4) una cantidad suficiente de sílice pirógena para actuar como modificador reológico en la composición y conferir un índice de reducción de cizalla a la composición, medido a velocidad de cizalla de 1 s- 1 y 10 s- 1 a 37ºC de al menos 4.
Applications Claiming Priority (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45028803P | 2003-02-26 | 2003-02-26 | |
US45028903P | 2003-02-26 | 2003-02-26 | |
US45062603P | 2003-02-26 | 2003-02-26 | |
US45122803P | 2003-02-27 | 2003-02-27 | |
US45131003P | 2003-02-27 | 2003-02-27 | |
US46117703P | 2003-04-07 | 2003-04-07 | |
US46128903P | 2003-04-07 | 2003-04-07 | |
US46128303P | 2003-04-07 | 2003-04-07 | |
US46128803P | 2003-04-07 | 2003-04-07 | |
US46129003P | 2003-04-07 | 2003-04-07 | |
PCT/US2004/005994 WO2004075989A1 (en) | 2003-02-26 | 2004-02-26 | Fumed silica embolic compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2311803T3 true ES2311803T3 (es) | 2009-02-16 |
Family
ID=32931806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES04715148T Expired - Lifetime ES2311803T3 (es) | 2003-02-26 | 2004-02-26 | Composiciones embolicas de silicie pirogena. |
Country Status (6)
Country | Link |
---|---|
US (1) | US20040224864A1 (es) |
EP (1) | EP1599258B1 (es) |
AT (1) | ATE403469T1 (es) |
DE (1) | DE602004015574D1 (es) |
ES (1) | ES2311803T3 (es) |
WO (1) | WO2004075989A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040156781A1 (en) * | 2002-10-15 | 2004-08-12 | Porter Christopher H. | Polymeric materials for site specific delivery to the body |
US20040228797A1 (en) * | 2003-03-07 | 2004-11-18 | Bein Richard S. | Compositions for use in embolizing blood vessels comprising high levels of contrast agent |
US8173176B2 (en) * | 2004-03-30 | 2012-05-08 | Boston Scientific Scimed, Inc. | Embolization |
US7311861B2 (en) | 2004-06-01 | 2007-12-25 | Boston Scientific Scimed, Inc. | Embolization |
US8021744B2 (en) | 2004-06-18 | 2011-09-20 | Borgwarner Inc. | Fully fibrous structure friction material |
US8603614B2 (en) | 2004-07-26 | 2013-12-10 | Borgwarner Inc. | Porous friction material with nanoparticles of friction modifying material |
US7429418B2 (en) * | 2004-07-26 | 2008-09-30 | Borgwarner, Inc. | Porous friction material comprising nanoparticles of friction modifying material |
US20060142631A1 (en) * | 2004-12-29 | 2006-06-29 | Attila Meretei | Systems and methods for occluding a blood vessel |
JP5468252B2 (ja) | 2005-04-26 | 2014-04-09 | ボーグワーナー インコーポレーテッド | 摩擦材料 |
US7963287B2 (en) | 2005-04-28 | 2011-06-21 | Boston Scientific Scimed, Inc. | Tissue-treatment methods |
US9463426B2 (en) | 2005-06-24 | 2016-10-11 | Boston Scientific Scimed, Inc. | Methods and systems for coating particles |
US8394452B2 (en) | 2005-11-02 | 2013-03-12 | Borgwarner Inc. | Carbon friction materials |
JP2010500917A (ja) | 2006-06-15 | 2010-01-14 | マイクロベンション, インコーポレイテッド | 膨張性ポリマーで構成される塞栓形成デバイス |
CA2709379C (en) | 2007-12-21 | 2016-08-16 | Microvention, Inc. | Hydrogel filaments for biomedical uses |
DE102008013907B4 (de) | 2008-03-12 | 2016-03-10 | Borgwarner Inc. | Reibschlüssig arbeitende Vorrichtung mit mindestens einer Reiblamelle |
DE102009030506A1 (de) | 2008-06-30 | 2009-12-31 | Borgwarner Inc., Auburn Hills | Reibungsmaterialien |
WO2011053555A1 (en) | 2009-10-26 | 2011-05-05 | Microvention, Inc. | Embolization device constructed from expansile polymer |
IT1400620B1 (it) * | 2010-05-13 | 2013-06-14 | Torino Politecnico | Cementi ossei compositi iniettabili, osteoinduttivi ed a rilascio di farmaci |
US9456823B2 (en) | 2011-04-18 | 2016-10-04 | Terumo Corporation | Embolic devices |
WO2013158781A1 (en) | 2012-04-18 | 2013-10-24 | Microvention, Inc. | Embolic devices |
CN104363922B (zh) | 2012-06-14 | 2017-06-30 | 微仙美国有限公司 | 聚合物治疗组合物 |
AU2013331439B2 (en) | 2012-10-15 | 2016-05-12 | Microvention, Inc. | Polymeric treatment compositions |
US10124090B2 (en) | 2014-04-03 | 2018-11-13 | Terumo Corporation | Embolic devices |
CN110433326A (zh) | 2014-04-29 | 2019-11-12 | 微仙美国有限公司 | 包含活性剂的聚合物 |
US10092663B2 (en) | 2014-04-29 | 2018-10-09 | Terumo Corporation | Polymers |
WO2016201250A1 (en) | 2015-06-11 | 2016-12-15 | Microvention, Inc. | Expansile device for implantation |
EP4353311A3 (en) * | 2015-07-20 | 2024-07-17 | The Brigham and Women's Hospital, Inc. | Shear-thinning compositions as an intravascular embolic agent |
US10368874B2 (en) | 2016-08-26 | 2019-08-06 | Microvention, Inc. | Embolic compositions |
US10576182B2 (en) | 2017-10-09 | 2020-03-03 | Microvention, Inc. | Radioactive liquid embolic |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5273728A (en) * | 1990-09-04 | 1993-12-28 | The Dow Chemical Company | Mixed metal layered hydroxide/fumed silica adducts |
ES2104359T3 (es) * | 1993-02-12 | 1997-10-01 | Cabot Corp | Silice modificada superficialmente. |
JP3351595B2 (ja) * | 1993-12-22 | 2002-11-25 | 株式会社日立製作所 | 半導体メモリ装置 |
US5618522A (en) * | 1995-01-20 | 1997-04-08 | The Procter & Gamble Company | Emulsion compositions |
US6139819A (en) * | 1995-06-07 | 2000-10-31 | Imarx Pharmaceutical Corp. | Targeted contrast agents for diagnostic and therapeutic use |
US5580568A (en) * | 1995-07-27 | 1996-12-03 | Micro Therapeutics, Inc. | Cellulose diacetate compositions for use in embolizing blood vessels |
US5695480A (en) * | 1996-07-29 | 1997-12-09 | Micro Therapeutics, Inc. | Embolizing compositions |
US6645167B1 (en) * | 1999-05-21 | 2003-11-11 | Micro Therapeutics, Inc. | Methods for embolizing vascular sites with an embolizing composition |
JP5148030B2 (ja) * | 1999-05-21 | 2013-02-20 | タイコ ヘルスケア グループ リミテッド パートナーシップ | 新規の高粘度塞栓形成組成物 |
US7018365B2 (en) * | 1999-05-21 | 2006-03-28 | Micro Therapeutics, Inc. | Threaded syringe with quick stop |
WO2002087416A2 (en) * | 2001-04-26 | 2002-11-07 | Porter Christopher H | Method and apparatus for delivering materials to the body |
US7687053B2 (en) * | 2001-08-20 | 2010-03-30 | Boston Scientific Scimed, Inc. | Embolic compositions with non-cyanoacrylate rheology modifying agents |
US7341716B2 (en) * | 2002-04-12 | 2008-03-11 | Boston Scientific Scimed, Inc. | Occlusive composition |
US7459142B2 (en) * | 2002-06-06 | 2008-12-02 | Micro Therapeutics, Inc. | High viscosity embolizing compositions comprising prepolymers |
US20040156781A1 (en) * | 2002-10-15 | 2004-08-12 | Porter Christopher H. | Polymeric materials for site specific delivery to the body |
US20050025707A1 (en) * | 2003-02-27 | 2005-02-03 | Patterson William R. | Fumed silica embolic compositions |
-
2004
- 2004-02-26 ES ES04715148T patent/ES2311803T3/es not_active Expired - Lifetime
- 2004-02-26 AT AT04715148T patent/ATE403469T1/de not_active IP Right Cessation
- 2004-02-26 EP EP04715148A patent/EP1599258B1/en not_active Expired - Lifetime
- 2004-02-26 WO PCT/US2004/005994 patent/WO2004075989A1/en active Application Filing
- 2004-02-26 DE DE602004015574T patent/DE602004015574D1/de not_active Expired - Lifetime
- 2004-02-26 US US10/789,944 patent/US20040224864A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE602004015574D1 (de) | 2008-09-18 |
ATE403469T1 (de) | 2008-08-15 |
EP1599258B1 (en) | 2008-08-06 |
EP1599258A1 (en) | 2005-11-30 |
US20040224864A1 (en) | 2004-11-11 |
WO2004075989A1 (en) | 2004-09-10 |
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