ES2309705T3 - Nueva combinacion de anticolinergico y beta-mimeticos para el tratamiento de enfermedades respiratorias. - Google Patents
Nueva combinacion de anticolinergico y beta-mimeticos para el tratamiento de enfermedades respiratorias. Download PDFInfo
- Publication number
- ES2309705T3 ES2309705T3 ES05701139T ES05701139T ES2309705T3 ES 2309705 T3 ES2309705 T3 ES 2309705T3 ES 05701139 T ES05701139 T ES 05701139T ES 05701139 T ES05701139 T ES 05701139T ES 2309705 T3 ES2309705 T3 ES 2309705T3
- Authority
- ES
- Spain
- Prior art keywords
- glycopyrrolate
- formoterol
- physiologically acceptable
- treatment
- salmeterol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- A—HUMAN NECESSITIES
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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- A—HUMAN NECESSITIES
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54195704P | 2004-02-06 | 2004-02-06 | |
| US541957P | 2004-02-06 |
Publications (1)
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|---|---|
| ES2309705T3 true ES2309705T3 (es) | 2008-12-16 |
Family
ID=34837534
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| JP (1) | JP5524442B2 (https=) |
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| AT (1) | ATE399027T1 (https=) |
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| CA (1) | CA2550841C (https=) |
| CY (1) | CY1108326T1 (https=) |
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| ES (1) | ES2309705T3 (https=) |
| HR (1) | HRP20080439T3 (https=) |
| NO (1) | NO337128B1 (https=) |
| NZ (1) | NZ548302A (https=) |
| PL (1) | PL1718336T3 (https=) |
| PT (1) | PT1718336E (https=) |
| RU (1) | RU2438660C2 (https=) |
| SI (1) | SI1718336T1 (https=) |
| WO (1) | WO2005074900A2 (https=) |
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| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| EP1713473B1 (en) * | 2004-02-06 | 2013-03-13 | MEDA Pharma GmbH & Co. KG | The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and copd |
| GB0410398D0 (en) * | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
| ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| NZ591969A (en) * | 2005-12-21 | 2012-05-25 | Meda Pharma Gmbh & Co Kg | Combination of anticholinergics, glucocorticoids, beta2-adrenoceptor agonists, PDE 4 inhibitor and antileukotriene for the treatment of inflammatory diseases |
| US20080031828A1 (en) * | 2006-08-03 | 2008-02-07 | Boehringer Ingelheim International Gmbh | Method for the Treatment of Dyspnea Comprising Combined Administration of Tiotropium Salts and Salts of Salmeterol |
| EP1944018A1 (en) * | 2007-01-10 | 2008-07-16 | CHIESI FARMACEUTICI S.p.A. | Micronised particles of low-dosage strength active agents for powder formulations for inhalation |
| GB0801876D0 (en) | 2008-02-01 | 2008-03-12 | Vectura Group Plc | Suspension formulations |
| GB2468073B (en) * | 2008-02-26 | 2012-09-05 | Elevation Pharmaceuticals Inc | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
| US20100055045A1 (en) * | 2008-02-26 | 2010-03-04 | William Gerhart | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2221048A1 (en) * | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Pharmaceutical composition for inhalation |
| MX337126B (es) | 2009-05-29 | 2016-02-12 | Pearl Therapeutics Inc | Administracion respiratoria de agentes activos. |
| US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
| WO2010144628A2 (en) * | 2009-06-09 | 2010-12-16 | Elevation Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
| WO2011076842A2 (en) | 2009-12-23 | 2011-06-30 | Chiesi Farmaceutici S.P.A. | Aerosol formulation for copd |
| ES2467928T3 (es) * | 2009-12-23 | 2014-06-13 | Chiesi Farmaceutici S.P.A. | Formulación en aerosol para EPOC |
| EP2515853B1 (en) * | 2009-12-23 | 2014-03-19 | Chiesi Farmaceutici S.p.A. | Combination therapy for COPD |
| UA113832C2 (xx) * | 2009-12-23 | 2017-03-27 | Комбінаційна терапія для хозл | |
| EP2749283A3 (en) * | 2011-02-17 | 2014-08-20 | Cipla Limited | Combination of glycopyrronium and olodaterol |
| JO3510B1 (ar) * | 2011-03-04 | 2020-07-05 | Heptares Therapeutics Ltd | استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| CA2835927A1 (en) * | 2011-05-17 | 2012-11-22 | Pearl Therapeutics, Inc. | Compositions, methods & systems for respiratory delivery of two or more active agents |
| KR102391332B1 (ko) | 2013-03-15 | 2022-04-26 | 펄 테라퓨틱스 인코포레이티드 | 미립자 결정질 재료를 컨디셔닝하는 방법 및 시스템 |
| LT3096737T (lt) * | 2013-12-30 | 2018-06-11 | Chiesi Farmaceutici S.P.A. | Stabili glikopironio bromido ir formoterolio derinio suspausto aerozolio tirpalo kompozicija |
| EP3384898A1 (en) | 2013-12-30 | 2018-10-10 | Chiesi Farmaceutici S.p.A. | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
| WO2017077488A1 (en) * | 2015-11-04 | 2017-05-11 | Glenmark Pharmaceuticals Limited | An inhalable fixed dose powder composition comprising glycopyrronium and formoterol |
| AU2019477296A1 (en) | 2019-12-02 | 2022-04-14 | Chiesi Farmaceutici S.P.A. | Stainles steel can for pressurised metered dose inhalers |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998000016A1 (en) * | 1996-07-01 | 1998-01-08 | Sepracor, Inc. | Methods and compositions for treating urinary incontinence using enantiomerically enriched (r,r)-glycopyrrolate |
| DK0937041T3 (da) | 1996-11-11 | 2003-08-11 | Christian R Noe | Anvendelse af et farmaceutisk egnet salt af (3R,2'R)-3-[(cyclopentil-hydroxyphenylacetyl)oxyl]-1,1-dimethyl-pyrrolidinium til fremstilling af et lægemiddel |
| JP4570251B2 (ja) | 1998-07-24 | 2010-10-27 | ヤゴテック アーゲー | 医薬用エーロゾル製剤 |
| CN1150890C (zh) * | 1998-08-04 | 2004-05-26 | 杰格研究股份公司 | 药用气溶胶制剂 |
| AU756852B2 (en) * | 1998-11-13 | 2003-01-23 | Jagotec Ag | Dry powder for inhalation |
| DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
| US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
| DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
| GB0008485D0 (en) * | 2000-04-07 | 2000-05-24 | Glaxo Group Ltd | Pharmaceutical compositions |
| GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
| NZ528640A (en) * | 2001-03-30 | 2004-06-25 | Jagotec Ag | Medical aerosol formulations |
| US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
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- 2005-01-24 ES ES05701139T patent/ES2309705T3/es not_active Expired - Lifetime
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- 2005-01-24 SI SI200530323T patent/SI1718336T1/sl unknown
- 2005-01-24 CA CA2550841A patent/CA2550841C/en not_active Expired - Fee Related
- 2005-01-24 CN CNA2005800019327A patent/CN1905902A/zh active Pending
- 2005-01-24 HR HR20080439T patent/HRP20080439T3/xx unknown
- 2005-01-24 AT AT05701139T patent/ATE399027T1/de active
- 2005-01-24 WO PCT/EP2005/000649 patent/WO2005074900A2/en not_active Ceased
- 2005-01-24 AU AU2005210083A patent/AU2005210083B2/en not_active Ceased
- 2005-01-24 DK DK05701139T patent/DK1718336T3/da active
- 2005-01-24 EP EP05701139A patent/EP1718336B1/en not_active Expired - Lifetime
- 2005-01-24 JP JP2006551761A patent/JP5524442B2/ja not_active Expired - Fee Related
- 2005-01-24 NZ NZ548302A patent/NZ548302A/en not_active IP Right Cessation
- 2005-01-24 DE DE602005007708T patent/DE602005007708D1/de not_active Expired - Lifetime
- 2005-02-07 US US11/051,469 patent/US20050175549A1/en not_active Abandoned
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2006
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- 2006-08-31 NO NO20063882A patent/NO337128B1/no not_active IP Right Cessation
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2007
- 2007-07-30 US US11/882,109 patent/US7985766B2/en active Active
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2008
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Also Published As
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| DK1718336T3 (da) | 2008-10-20 |
| EP1718336B1 (en) | 2008-06-25 |
| CY1108326T1 (el) | 2014-02-12 |
| CA2550841A1 (en) | 2005-08-18 |
| WO2005074900A2 (en) | 2005-08-18 |
| SI1718336T1 (sl) | 2008-10-31 |
| US20070270481A1 (en) | 2007-11-22 |
| JP5524442B2 (ja) | 2014-06-18 |
| US20050175549A1 (en) | 2005-08-11 |
| HRP20080439T3 (hr) | 2008-10-31 |
| PL1718336T3 (pl) | 2008-11-28 |
| ATE399027T1 (de) | 2008-07-15 |
| NO20063882L (no) | 2006-10-26 |
| US20060252815A1 (en) | 2006-11-09 |
| NO337128B1 (no) | 2016-01-25 |
| RU2006132036A (ru) | 2008-03-20 |
| AU2005210083A1 (en) | 2005-08-18 |
| DE602005007708D1 (de) | 2008-08-07 |
| NZ548302A (en) | 2010-04-30 |
| AU2005210083B2 (en) | 2010-03-11 |
| EP1718336A2 (en) | 2006-11-08 |
| WO2005074900A3 (en) | 2006-04-06 |
| RU2438660C2 (ru) | 2012-01-10 |
| PT1718336E (pt) | 2008-08-28 |
| JP2007520506A (ja) | 2007-07-26 |
| CA2550841C (en) | 2012-10-02 |
| CN1905902A (zh) | 2007-01-31 |
| US7985766B2 (en) | 2011-07-26 |
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