HRP20080439T3 - Nova kombinacija antikolinergika i beta mimetika za liječenje respiratornih bolesti - Google Patents
Nova kombinacija antikolinergika i beta mimetika za liječenje respiratornih bolestiInfo
- Publication number
- HRP20080439T3 HRP20080439T3 HR20080439T HRP20080439T HRP20080439T3 HR P20080439 T3 HRP20080439 T3 HR P20080439T3 HR 20080439 T HR20080439 T HR 20080439T HR P20080439 T HRP20080439 T HR P20080439T HR P20080439 T3 HRP20080439 T3 HR P20080439T3
- Authority
- HR
- Croatia
- Prior art keywords
- anticholinergic
- treatment
- respiratory diseases
- novel combination
- beta mimetics
- Prior art date
Links
- 230000001078 anti-cholinergic effect Effects 0.000 title abstract 2
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- 239000000808 adrenergic beta-agonist Substances 0.000 title 1
- 230000003454 betamimetic effect Effects 0.000 title 1
- 208000000884 Airway Obstruction Diseases 0.000 abstract 1
- 208000006545 Chronic Obstructive Pulmonary Disease Diseases 0.000 abstract 1
- 208000037883 airway inflammation Diseases 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 229940015042 glycopyrrolate Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Abstract
Uporaba kombinacije R,R-glikopirolata ili jedne od njegovih fiziološki prihvatljivih soli i ß2-mimetičkog agensa dugotrajnog djelovanja, izabranog izskupine koja obuhvaća formoterol ili salmeterol ili njihove fiziološki prihvatljive soli, naznačenatime, da je za proizvodnju lijeka za liječenje astme ili KOPB. Patent sadrži još 13 patentnih zahtjeva.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54195704P | 2004-02-06 | 2004-02-06 | |
PCT/EP2005/000649 WO2005074900A2 (en) | 2004-02-06 | 2005-01-24 | NOVEL COMBINATION OF ANTICHOLINERGIC AND β MIMETICS FOR THE TREATMENT OF RESPIRATORY DISEASES |
Publications (1)
Publication Number | Publication Date |
---|---|
HRP20080439T3 true HRP20080439T3 (hr) | 2008-10-31 |
Family
ID=34837534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HR20080439T HRP20080439T3 (hr) | 2004-02-06 | 2008-09-10 | Nova kombinacija antikolinergika i beta mimetika za liječenje respiratornih bolesti |
Country Status (19)
Country | Link |
---|---|
US (3) | US20050175549A1 (hr) |
EP (1) | EP1718336B1 (hr) |
JP (1) | JP5524442B2 (hr) |
CN (1) | CN1905902A (hr) |
AT (1) | ATE399027T1 (hr) |
AU (1) | AU2005210083B2 (hr) |
CA (1) | CA2550841C (hr) |
CY (1) | CY1108326T1 (hr) |
DE (1) | DE602005007708D1 (hr) |
DK (1) | DK1718336T3 (hr) |
ES (1) | ES2309705T3 (hr) |
HR (1) | HRP20080439T3 (hr) |
NO (1) | NO337128B1 (hr) |
NZ (1) | NZ548302A (hr) |
PL (1) | PL1718336T3 (hr) |
PT (1) | PT1718336E (hr) |
RU (1) | RU2438660C2 (hr) |
SI (1) | SI1718336T1 (hr) |
WO (1) | WO2005074900A2 (hr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
JP4819699B2 (ja) * | 2004-02-06 | 2011-11-24 | メダ ファーマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディト ゲゼルシャフト | 喘息及びcopdの長期間の治療のための抗コリン作用薬及びグルココルチコイドの組合せ剤 |
GB0410398D0 (en) * | 2004-05-10 | 2004-06-16 | Arakis Ltd | The treatment of respiratory disease |
ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
ES2330047T3 (es) * | 2005-12-21 | 2009-12-03 | MEDA PHARMA GMBH & CO. KG | Combinacion de r,r-glicopirrolato, rolipram y budesonida para el tratmiento de enfermedades inflamatorias. |
US20080031828A1 (en) * | 2006-08-03 | 2008-02-07 | Boehringer Ingelheim International Gmbh | Method for the Treatment of Dyspnea Comprising Combined Administration of Tiotropium Salts and Salts of Salmeterol |
EP1944018A1 (en) * | 2007-01-10 | 2008-07-16 | CHIESI FARMACEUTICI S.p.A. | Micronised particles of low-dosage strength active agents for powder formulations for inhalation |
GB0801876D0 (en) | 2008-02-01 | 2008-03-12 | Vectura Group Plc | Suspension formulations |
US20100055045A1 (en) * | 2008-02-26 | 2010-03-04 | William Gerhart | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
US20090215734A1 (en) * | 2008-02-26 | 2009-08-27 | Elevation Pharmaceuticals, Inc. | Method and system for the treatment of chronic obstructive pulmonary disease with nebulized anticholinergic administrations |
EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2221048A1 (en) * | 2009-02-18 | 2010-08-25 | Siegfried Generics International AG | Pharmaceutical composition for inhalation |
US8815258B2 (en) | 2009-05-29 | 2014-08-26 | Pearl Therapeutics, Inc. | Compositions, methods and systems for respiratory delivery of two or more active agents |
PL3106149T3 (pl) * | 2009-05-29 | 2020-06-01 | Pearl Therapeutics, Inc. | Kompozycje do płucnego dostarczania długo-działających antagonistów muskarynowych i długo-działających agonistów receptora beta-2 adrenergicznego oraz powiązane sposoby i układy |
CA2764867C (en) * | 2009-06-09 | 2016-05-17 | Elevation Pharmaceuticals, Inc. | Treatment of chronic obstructive pulmonary disease with nebulized beta 2-agonist or combined nebulized beta 2-agonist and anticholinergic administration |
ES2467928T3 (es) * | 2009-12-23 | 2014-06-13 | Chiesi Farmaceutici S.P.A. | Formulación en aerosol para EPOC |
CA2785317C (en) | 2009-12-23 | 2018-02-27 | Chiesi Farmaceutici S.P.A. | Aerosol formulation for copd |
CN102665679B (zh) * | 2009-12-23 | 2014-11-26 | 奇斯药制品公司 | 用于copd的联合治疗 |
RU2561052C2 (ru) * | 2009-12-23 | 2015-08-20 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Комбинированное лечение хронического обструктивного заболевания легких |
KR20140012989A (ko) * | 2011-02-17 | 2014-02-04 | 시플라 리미티드 | 글리코피롤레이트 및 베타2-효능제의 조합 |
JO3510B1 (ar) | 2011-03-04 | 2020-07-05 | Heptares Therapeutics Ltd | استخدام جلايكوبيرولات لعلاج عدم انتظام دقات القلب |
EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
SG194896A1 (en) * | 2011-05-17 | 2013-12-30 | Pearl Therapeutics Inc | Compositions, methods & systems for respiratory delivery of two or more active agents |
JP6454323B2 (ja) | 2013-03-15 | 2019-01-16 | パール セラピューティクス,インコーポレイテッド | 粒子状結晶性材料のコンディショニングのための方法及びシステム |
MY182861A (en) * | 2013-12-30 | 2021-02-05 | Chiesi Farm Spa | Stable pressurised aerosol solution composition of glycopyrronium bromide and formoterol combination |
BR112016014586A2 (pt) * | 2013-12-30 | 2017-08-08 | Chiesi Farm Spa | Composição de solução de aerossol pressurizado estável da combinação de brometo de glicopirrônio e formoterol |
WO2017077488A1 (en) * | 2015-11-04 | 2017-05-11 | Glenmark Pharmaceuticals Limited | An inhalable fixed dose powder composition comprising glycopyrronium and formoterol |
MX2022004781A (es) | 2019-12-02 | 2022-05-16 | Chiesi Farm Spa | Lata de acero inoxidable para inhaladores dosificadores presurizados. |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1371645T3 (da) | 1996-11-11 | 2013-06-03 | Meda Pharma Gmbh & Co Kg | Anvendelse af (3S,2'R)-glycopyrronium som lægemiddel |
DE59911149D1 (de) | 1998-07-24 | 2004-12-30 | Jago Res Ag Muttenz | Medizinische aerosolformulierungen |
NZ509489A (en) * | 1998-08-04 | 2002-10-25 | Jago Res A | Medicinal aerosol formulations comprising cromoglycic acid and/or nedocromil |
SK284889B6 (sk) * | 1998-11-13 | 2006-02-02 | Jago Research Ag | Použitie stearátu horečnatého v suchých práškových formuláciách na inhaláciu |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
US20040002548A1 (en) * | 1999-05-12 | 2004-01-01 | Boehringer Ingelheim Pharma Kg | Medicament compositions containing anticholinergically-effective compounds and betamimetics |
DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
GB0008660D0 (en) * | 2000-04-07 | 2000-05-31 | Arakis Ltd | The treatment of respiratory diseases |
US20040101483A1 (en) * | 2001-03-30 | 2004-05-27 | Rudi Muller-Walz | Medical aerosol formulations |
US6667344B2 (en) * | 2001-04-17 | 2003-12-23 | Dey, L.P. | Bronchodilating compositions and methods |
-
2005
- 2005-01-24 CA CA2550841A patent/CA2550841C/en not_active Expired - Fee Related
- 2005-01-24 PL PL05701139T patent/PL1718336T3/pl unknown
- 2005-01-24 WO PCT/EP2005/000649 patent/WO2005074900A2/en active IP Right Grant
- 2005-01-24 SI SI200530323T patent/SI1718336T1/sl unknown
- 2005-01-24 EP EP05701139A patent/EP1718336B1/en active Active
- 2005-01-24 AU AU2005210083A patent/AU2005210083B2/en not_active Ceased
- 2005-01-24 RU RU2006132036/15A patent/RU2438660C2/ru not_active Application Discontinuation
- 2005-01-24 ES ES05701139T patent/ES2309705T3/es active Active
- 2005-01-24 CN CNA2005800019327A patent/CN1905902A/zh active Pending
- 2005-01-24 AT AT05701139T patent/ATE399027T1/de active
- 2005-01-24 NZ NZ548302A patent/NZ548302A/en unknown
- 2005-01-24 PT PT05701139T patent/PT1718336E/pt unknown
- 2005-01-24 JP JP2006551761A patent/JP5524442B2/ja not_active Expired - Fee Related
- 2005-01-24 DK DK05701139T patent/DK1718336T3/da active
- 2005-01-24 DE DE602005007708T patent/DE602005007708D1/de active Active
- 2005-02-07 US US11/051,469 patent/US20050175549A1/en not_active Abandoned
-
2006
- 2006-07-11 US US11/483,693 patent/US20060252815A1/en not_active Abandoned
- 2006-08-31 NO NO20063882A patent/NO337128B1/no not_active IP Right Cessation
-
2007
- 2007-07-30 US US11/882,109 patent/US7985766B2/en active Active
-
2008
- 2008-09-10 HR HR20080439T patent/HRP20080439T3/hr unknown
- 2008-09-10 CY CY20081100967T patent/CY1108326T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP5524442B2 (ja) | 2014-06-18 |
CA2550841A1 (en) | 2005-08-18 |
NO20063882L (no) | 2006-10-26 |
CN1905902A (zh) | 2007-01-31 |
WO2005074900A2 (en) | 2005-08-18 |
US7985766B2 (en) | 2011-07-26 |
SI1718336T1 (sl) | 2008-10-31 |
ES2309705T3 (es) | 2008-12-16 |
AU2005210083B2 (en) | 2010-03-11 |
US20070270481A1 (en) | 2007-11-22 |
PT1718336E (pt) | 2008-08-28 |
PL1718336T3 (pl) | 2008-11-28 |
RU2438660C2 (ru) | 2012-01-10 |
US20060252815A1 (en) | 2006-11-09 |
CA2550841C (en) | 2012-10-02 |
WO2005074900A3 (en) | 2006-04-06 |
NO337128B1 (no) | 2016-01-25 |
CY1108326T1 (el) | 2014-02-12 |
JP2007520506A (ja) | 2007-07-26 |
NZ548302A (en) | 2010-04-30 |
RU2006132036A (ru) | 2008-03-20 |
AU2005210083A1 (en) | 2005-08-18 |
EP1718336B1 (en) | 2008-06-25 |
US20050175549A1 (en) | 2005-08-11 |
EP1718336A2 (en) | 2006-11-08 |
DE602005007708D1 (de) | 2008-08-07 |
DK1718336T3 (da) | 2008-10-20 |
ATE399027T1 (de) | 2008-07-15 |
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