ES2297233T3 - Uso de brimonidina en el tratamiento de demencia y enfermedad de parkinson. - Google Patents
Uso de brimonidina en el tratamiento de demencia y enfermedad de parkinson. Download PDFInfo
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- ES2297233T3 ES2297233T3 ES03773199T ES03773199T ES2297233T3 ES 2297233 T3 ES2297233 T3 ES 2297233T3 ES 03773199 T ES03773199 T ES 03773199T ES 03773199 T ES03773199 T ES 03773199T ES 2297233 T3 ES2297233 T3 ES 2297233T3
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- 239000002464 receptor antagonist Substances 0.000 description 1
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- 230000001105 regulatory effect Effects 0.000 description 1
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- 229940125723 sedative agent Drugs 0.000 description 1
- IYETZZCWLLUHIJ-UTONKHPSSA-N selegiline hydrochloride Chemical compound [Cl-].C#CC[NH+](C)[C@H](C)CC1=CC=CC=C1 IYETZZCWLLUHIJ-UTONKHPSSA-N 0.000 description 1
- 229960003678 selegiline hydrochloride Drugs 0.000 description 1
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- 230000000862 serotonergic effect Effects 0.000 description 1
- 230000007727 signaling mechanism Effects 0.000 description 1
- 229940001089 sinemet Drugs 0.000 description 1
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- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
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- 210000000331 sympathetic ganglia Anatomy 0.000 description 1
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- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 229960001685 tacrine Drugs 0.000 description 1
- YLJREFDVOIBQDA-UHFFFAOYSA-N tacrine Chemical compound C1=CC=C2C(N)=C(CCCC3)C3=NC2=C1 YLJREFDVOIBQDA-UHFFFAOYSA-N 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- VCKUSRYTPJJLNI-UHFFFAOYSA-N terazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1CCCO1 VCKUSRYTPJJLNI-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41703102P | 2002-10-08 | 2002-10-08 | |
| US417031P | 2002-10-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2297233T3 true ES2297233T3 (es) | 2008-05-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES03773199T Expired - Lifetime ES2297233T3 (es) | 2002-10-08 | 2003-10-07 | Uso de brimonidina en el tratamiento de demencia y enfermedad de parkinson. |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20040116436A1 (enExample) |
| EP (1) | EP1549314B1 (enExample) |
| JP (1) | JP2006504741A (enExample) |
| KR (1) | KR20050056235A (enExample) |
| CN (1) | CN100370988C (enExample) |
| AT (1) | ATE380551T1 (enExample) |
| AU (2) | AU2003279874A1 (enExample) |
| BR (1) | BR0314541A (enExample) |
| CA (1) | CA2501348A1 (enExample) |
| DE (1) | DE60318081T2 (enExample) |
| ES (1) | ES2297233T3 (enExample) |
| HK (1) | HK1080408B (enExample) |
| IL (1) | IL167848A (enExample) |
| MX (1) | MXPA05003665A (enExample) |
| NO (1) | NO20051664L (enExample) |
| NZ (1) | NZ539329A (enExample) |
| PL (1) | PL376347A1 (enExample) |
| RU (1) | RU2332218C2 (enExample) |
| WO (1) | WO2004032934A1 (enExample) |
| ZA (1) | ZA200502745B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7512436B2 (en) * | 2004-02-12 | 2009-03-31 | The Regents Of The University Of Michigan | Method of evaluating metabolism of the eye |
| US9095506B2 (en) | 2008-11-17 | 2015-08-04 | Allergan, Inc. | Biodegradable alpha-2 agonist polymeric implants and therapeutic uses thereof |
| US20100298305A1 (en) * | 2008-11-26 | 2010-11-25 | The United States Government, As Represented By The Department Of Veterans Affairs | Tizanidine for the treatment of post-traumatic stress disorder and nightmares |
| DE102009043750A1 (de) * | 2009-09-30 | 2011-08-04 | Carl Zeiss Meditec AG, 07745 | Verfahren und Vorrichtung zur Detektion von Ablagerungen im Auge |
| WO2016089997A1 (en) * | 2014-12-02 | 2016-06-09 | Yale University | Methods of preventing neurodegeneration of association cortex in a mammal |
| RU2680526C1 (ru) * | 2016-07-05 | 2019-02-22 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Нейропротекторное средство, обладающее свойствами антиоксиданта и донатора оксида азота |
| CA3031528A1 (en) * | 2016-08-01 | 2018-02-08 | Cognoptix, Inc. | System and method for detecting tau protein in ocular tissue |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE795970A (fr) * | 1972-02-29 | 1973-08-27 | Pfizer | Nouveaux derives de quinoleine, quinoxaline et quinazoline er composition pharmaceutiques les contenant |
| US4029792A (en) * | 1972-02-29 | 1977-06-14 | Pfizer Inc. | (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents |
| US5210076A (en) * | 1988-09-13 | 1993-05-11 | Berliner David L | Methods of treating Parkinson's disease using melanin |
| WO1996037226A2 (en) * | 1995-05-26 | 1996-11-28 | Pfizer Inc. | Combinations for the treatment of parkinsonism containing selective nmda antagonists |
| US6194415B1 (en) * | 1995-06-28 | 2001-02-27 | Allergan Sales, Inc. | Method of using (2-imidazolin-2-ylamino) quinoxoalines in treating neural injury |
| US6841684B2 (en) * | 1997-12-04 | 2005-01-11 | Allergan, Inc. | Imidiazoles having reduced side effects |
| DE69823868T2 (de) * | 1997-12-04 | 2005-04-21 | Allergan Inc | Substituierte imidazole derivate mit agonistischähnlicher wirkung auf die alpha 2b oder 2b/2c adrenergischen rezeptoren |
| US6329369B1 (en) * | 1997-12-04 | 2001-12-11 | Allergan Sales, Inc. | Methods of treating pain and other conditions |
| US6313172B1 (en) * | 2000-04-13 | 2001-11-06 | Allergan Sales, Inc. | Methods and compositions for modulating alpha adrenergic receptor activity |
| CA2402405C (en) * | 2000-07-14 | 2008-02-12 | Allergan Sales, Inc. | Compositions containing alpha-2-adrenergic agonist components |
-
2003
- 2003-10-07 PL PL03376347A patent/PL376347A1/xx not_active Application Discontinuation
- 2003-10-07 US US10/680,996 patent/US20040116436A1/en not_active Abandoned
- 2003-10-07 CN CNB2003801011164A patent/CN100370988C/zh not_active Expired - Fee Related
- 2003-10-07 RU RU2005114505/14A patent/RU2332218C2/ru not_active IP Right Cessation
- 2003-10-07 WO PCT/US2003/031842 patent/WO2004032934A1/en not_active Ceased
- 2003-10-07 MX MXPA05003665A patent/MXPA05003665A/es active IP Right Grant
- 2003-10-07 ES ES03773199T patent/ES2297233T3/es not_active Expired - Lifetime
- 2003-10-07 NZ NZ539329A patent/NZ539329A/en not_active IP Right Cessation
- 2003-10-07 DE DE60318081T patent/DE60318081T2/de not_active Expired - Lifetime
- 2003-10-07 BR BR0314541-7A patent/BR0314541A/pt not_active IP Right Cessation
- 2003-10-07 KR KR1020057006115A patent/KR20050056235A/ko not_active Ceased
- 2003-10-07 CA CA002501348A patent/CA2501348A1/en not_active Abandoned
- 2003-10-07 AT AT03773199T patent/ATE380551T1/de not_active IP Right Cessation
- 2003-10-07 JP JP2004543508A patent/JP2006504741A/ja active Pending
- 2003-10-07 HK HK06100172.4A patent/HK1080408B/en not_active IP Right Cessation
- 2003-10-07 AU AU2003279874A patent/AU2003279874A1/en not_active Abandoned
- 2003-10-07 EP EP03773199A patent/EP1549314B1/en not_active Expired - Lifetime
-
2005
- 2005-04-04 IL IL167848A patent/IL167848A/en not_active IP Right Cessation
- 2005-04-04 NO NO20051664A patent/NO20051664L/no not_active Application Discontinuation
- 2005-04-05 ZA ZA200502745A patent/ZA200502745B/en unknown
-
2010
- 2010-02-26 AU AU2010200730A patent/AU2010200730A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040116436A1 (en) | 2004-06-17 |
| JP2006504741A (ja) | 2006-02-09 |
| MXPA05003665A (es) | 2005-06-08 |
| CN100370988C (zh) | 2008-02-27 |
| ZA200502745B (en) | 2006-07-26 |
| BR0314541A (pt) | 2005-07-26 |
| AU2010200730A1 (en) | 2010-03-18 |
| NZ539329A (en) | 2007-11-30 |
| CN1703222A (zh) | 2005-11-30 |
| HK1080408A1 (en) | 2006-04-28 |
| RU2332218C2 (ru) | 2008-08-27 |
| CA2501348A1 (en) | 2004-04-22 |
| RU2005114505A (ru) | 2005-10-27 |
| EP1549314B1 (en) | 2007-12-12 |
| WO2004032934A1 (en) | 2004-04-22 |
| NO20051664L (no) | 2005-05-31 |
| KR20050056235A (ko) | 2005-06-14 |
| IL167848A (en) | 2010-11-30 |
| DE60318081T2 (de) | 2008-11-06 |
| AU2003279874A1 (en) | 2004-05-04 |
| HK1080408B (en) | 2008-08-08 |
| EP1549314A1 (en) | 2005-07-06 |
| DE60318081D1 (de) | 2008-01-24 |
| PL376347A1 (en) | 2005-12-27 |
| ATE380551T1 (de) | 2007-12-15 |
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