ES2296872T3 - Peptidos derivados de tnf para uso en el tratamiento de edema. - Google Patents

Peptidos derivados de tnf para uso en el tratamiento de edema. Download PDF

Info

Publication number
ES2296872T3
ES2296872T3 ES02077256T ES02077256T ES2296872T3 ES 2296872 T3 ES2296872 T3 ES 2296872T3 ES 02077256 T ES02077256 T ES 02077256T ES 02077256 T ES02077256 T ES 02077256T ES 2296872 T3 ES2296872 T3 ES 2296872T3
Authority
ES
Spain
Prior art keywords
tnf
peptide
baselineskip
amino acids
peptide according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02077256T
Other languages
English (en)
Spanish (es)
Inventor
Patrick De Baetselier
Rudolf Lucas
Jerome Pugin
Alain Bloc
Lucie Fransen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2296872T3 publication Critical patent/ES2296872T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES02077256T 1998-08-14 1999-08-10 Peptidos derivados de tnf para uso en el tratamiento de edema. Expired - Lifetime ES2296872T3 (es)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP98870180 1998-08-14
EP98870180 1998-08-14
EP98870198 1998-09-18
EP98870198 1998-09-18
EP98870222 1998-10-21
EP98870222 1998-10-21

Publications (1)

Publication Number Publication Date
ES2296872T3 true ES2296872T3 (es) 2008-05-01

Family

ID=27239778

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02077256T Expired - Lifetime ES2296872T3 (es) 1998-08-14 1999-08-10 Peptidos derivados de tnf para uso en el tratamiento de edema.

Country Status (20)

Country Link
US (2) US20030105021A1 (enExample)
EP (3) EP1105152A1 (enExample)
JP (1) JP4542266B2 (enExample)
CN (1) CN1181886C (enExample)
AT (2) ATE395072T1 (enExample)
AU (1) AU764992B2 (enExample)
BR (1) BR9912899A (enExample)
CA (1) CA2334941C (enExample)
CZ (1) CZ302862B6 (enExample)
DE (2) DE69937206T2 (enExample)
DK (1) DK1264599T3 (enExample)
ES (1) ES2296872T3 (enExample)
HU (1) HU227661B1 (enExample)
IL (2) IL141064A0 (enExample)
NZ (1) NZ509604A (enExample)
PL (1) PL203706B1 (enExample)
PT (1) PT1264599E (enExample)
TR (1) TR200100338T2 (enExample)
WO (1) WO2000009149A1 (enExample)
ZA (1) ZA200100656B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ302862B6 (cs) 1998-08-14 2011-12-21 Lécivo na lécení otoku
JP5108515B2 (ja) * 2004-08-06 2012-12-26 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタント及びtnf由来ペプチドを含有する組成物
EP2009023A1 (en) * 2007-06-04 2008-12-31 Rentschler Beteiligungs GmbH Novel peptides and their use for the treatment of edema
AT506151B1 (de) 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Fusionsprotein
AT506150B1 (de) * 2007-12-12 2010-01-15 Apeptico Forschung Und Entwick Zyklisches und cystein-freies peptid
AT507953B1 (de) 2009-03-05 2011-02-15 Apeptico Forschung & Entwicklung Gmbh Verfahren zur vermeidung und zur behandlung einer hyperpermeabilität
AT509267A1 (de) 2010-01-14 2011-07-15 Apeptico Forschung & Entwicklung Gmbh Organische verbindungen zur regulierung von vektoriellen ionenkanälen
PL2397151T3 (pl) * 2010-06-21 2015-10-30 Apeptico Forschung & Entwicklung Gmbh Leczenie powikłań naczyniowych cukrzycy
AT510585B1 (de) 2010-11-18 2012-05-15 Apeptico Forschung & Entwicklung Gmbh Zusammensetzung umfassend ein peptid und ein hemmstoff der viralen neuraminidase
US11161881B2 (en) * 2010-11-18 2021-11-02 Apeptico Forschung Und Entwicklung Gmbh Composition comprising a peptide and an inhibitor of viral neuraminidase
EP2679239A1 (de) * 2012-06-28 2014-01-01 Apeptico Forschung und Entwicklung GmbH Pharmazeutische Zusammensetzung zur Behandlung der durch Sauerstoffarmut und verringerten Luftdruck vermittelten pulmonalen Form der Höhenkrankheit
US12004506B2 (en) 2013-04-23 2024-06-11 Apeptico Forschung Und Entwicklung Gmbh Pharmaceutical composition comprising a cyclic peptide of formula X1-GQRETPEGAEAKPWY-X2 and use for extracorporeal lung treatment
ES2813379T3 (es) * 2013-04-23 2021-03-23 Apeptico Forschung & Entwicklung Gmbh Tratamiento extracorporal del pulmón con un péptido cíclico de formula x1-gqretpegaeakpwy-x2
ES2665180T3 (es) 2014-03-18 2018-04-24 Apeptico Forschung Und Entwicklung Gmbh Medicamento de péptido en forma de polvo seco
CN110613838A (zh) * 2018-06-19 2019-12-27 姜石松 增强细胞通透性的多肽及其应用
CN120795059A (zh) 2018-08-27 2025-10-17 瑞泽恩制药公司 拉曼光谱在下游纯化中的应用
IL294894A (en) 2020-05-08 2022-09-01 Apeptico Forschung & Entwicklung Gmbh A peptide for the prevention or treatment of covid-19

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE384179C (de) * 1921-04-07 1923-10-27 Ludwig Weil Dr Laufrad fuer Kreiselpumpen und -geblaese
DE3841759A1 (de) 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
US5891679A (en) * 1993-02-03 1999-04-06 N.V. Innogenetics S.A. TNF-alpha muteins and a process for preparing them
CZ302862B6 (cs) 1998-08-14 2011-12-21 Lécivo na lécení otoku

Also Published As

Publication number Publication date
HUP0103117A2 (hu) 2001-12-28
CN1312724A (zh) 2001-09-12
CA2334941C (en) 2011-08-09
DE69938743D1 (de) 2008-06-26
CA2334941A1 (en) 2000-02-24
DK1264599T3 (da) 2008-02-04
CN1181886C (zh) 2004-12-29
EP1264599B1 (en) 2007-09-26
US20030105021A1 (en) 2003-06-05
WO2000009149A1 (en) 2000-02-24
NZ509604A (en) 2003-05-30
EP1105152A1 (en) 2001-06-13
DE69937206T2 (de) 2008-06-19
ATE395072T1 (de) 2008-05-15
HUP0103117A3 (en) 2004-03-01
JP4542266B2 (ja) 2010-09-08
PL345997A1 (en) 2002-01-14
US20030185791A1 (en) 2003-10-02
US7258861B2 (en) 2007-08-21
PL203706B1 (pl) 2009-11-30
HK1051805A1 (en) 2003-08-22
JP2002522508A (ja) 2002-07-23
IL141064A0 (en) 2002-02-10
AU764992B2 (en) 2003-09-04
CZ2001538A3 (cs) 2001-08-15
ATE374039T1 (de) 2007-10-15
PT1264599E (pt) 2008-01-07
AU5620999A (en) 2000-03-06
HU227661B1 (hu) 2011-10-28
ZA200100656B (en) 2005-06-29
DE69937206D1 (de) 2007-11-08
EP1264599A1 (en) 2002-12-11
BR9912899A (pt) 2001-05-08
EP1247531A3 (en) 2002-12-18
EP1247531B1 (en) 2008-05-14
CZ302862B6 (cs) 2011-12-21
EP1247531A2 (en) 2002-10-09
TR200100338T2 (tr) 2001-12-21
IL141064A (en) 2009-09-01

Similar Documents

Publication Publication Date Title
JP4542266B2 (ja) 浮腫の治療に使用されるtnf由来のペプチド
KR100725199B1 (ko) 에이치지에프유전자를함유하는약제
US20080095758A1 (en) Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage
ITRM970796A1 (it) Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
CN103038253A (zh) 作为用来稳定生物屏障的活性剂的肽
US9139615B2 (en) High-affinity, dimeric inhibitors of PSD-95 as efficient neuroprotectants against ischemic brain damage and for treatment of pain
Vasquez et al. Replication-Deficient Adenovirus Vector Transfer ofgfpReporter Gene into Supraoptic Nucleus and Subfornical Organ Neurons
ES2286644T3 (es) Compuestos destinados al tratamiento de enfermedades coronarias y/o vasculares perifericas.
PT90118B (pt) Processo para a preparacao de novos polipeptidos exibindo actividade de factor de crescimento e de sequencias de acidos nucleicos que codificam esses polipeptidos
HK1051805B (en) Tnf-derived peptides for use in treating oedema
HK1051802A (en) Tnf-derived peptides for use in treating oedema
US8372799B2 (en) Reverse protein
PT704219E (pt) Utilizacao de um factor proliferativo osteoblastico
MXPA01001527A (en) Tnf-derived peptides for use in treating oedema
KR20010102932A (ko) 안지오포이에틴-1을 포함하는 제약 조성물 및 그의 용도
KR101950502B1 (ko) 호흡기 염증을 현저히 줄이는 펩타이드 및 이를 포함하는 조성물
KR102702011B1 (ko) 폐내 염증의 완화
JPH083065A (ja) 肝臓障害に対する治療剤
WO2007054600A2 (es) Combinación de glicoisoformas para el tratamiento o prevención de la septicemia, línea celular transgénica productora de glicoformas de eritropoyetina, composición farmacéutica que comprende a dicha combinación
JP2020026397A (ja) TrkBアンタゴニストを含む医薬組成物
HK1136211B (en) Protease resistant mutants of stromal cell derived factor-1 in the repair of tissue damage