ES2266616T3 - Analogos de somatostatina que se unen a todos los receptores de somatostatina y su uso. - Google Patents

Analogos de somatostatina que se unen a todos los receptores de somatostatina y su uso. Download PDF

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Publication number
ES2266616T3
ES2266616T3 ES02794598T ES02794598T ES2266616T3 ES 2266616 T3 ES2266616 T3 ES 2266616T3 ES 02794598 T ES02794598 T ES 02794598T ES 02794598 T ES02794598 T ES 02794598T ES 2266616 T3 ES2266616 T3 ES 2266616T3
Authority
ES
Spain
Prior art keywords
somatostatin
group
somatostatin analogues
analogues according
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES02794598T
Other languages
English (en)
Spanish (es)
Inventor
Helmut Robert Maecke
Jean Claude Reubi
Hans Rink
Klaus-Peter Eisenwiener
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Bern
Universitaetsspital Basel USB
Original Assignee
Universitaet Bern
Universitaetsspital Basel USB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Bern, Universitaetsspital Basel USB filed Critical Universitaet Bern
Application granted granted Critical
Publication of ES2266616T3 publication Critical patent/ES2266616T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES02794598T 2001-08-10 2002-08-07 Analogos de somatostatina que se unen a todos los receptores de somatostatina y su uso. Expired - Lifetime ES2266616T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01203033A EP1283216A1 (en) 2001-08-10 2001-08-10 Somatostatin analogues binding to all somatostatin receptor subtypes and their use
EP01203033 2001-08-10

Publications (1)

Publication Number Publication Date
ES2266616T3 true ES2266616T3 (es) 2007-03-01

Family

ID=8180776

Family Applications (1)

Application Number Title Priority Date Filing Date
ES02794598T Expired - Lifetime ES2266616T3 (es) 2001-08-10 2002-08-07 Analogos de somatostatina que se unen a todos los receptores de somatostatina y su uso.

Country Status (12)

Country Link
US (2) US7192570B2 (https=)
EP (2) EP1283216A1 (https=)
JP (1) JP2005508886A (https=)
AT (1) ATE328005T1 (https=)
AU (1) AU2002333396B2 (https=)
CA (1) CA2456881A1 (https=)
CY (1) CY1105177T1 (https=)
DE (1) DE60211917T2 (https=)
DK (1) DK1419178T3 (https=)
ES (1) ES2266616T3 (https=)
PT (1) PT1419178E (https=)
WO (1) WO2003014158A1 (https=)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1283216A1 (en) 2001-08-10 2003-02-12 Mallinckrodt Inc. Somatostatin analogues binding to all somatostatin receptor subtypes and their use
NZ542371A (en) * 2003-03-19 2008-10-31 Universitatsspital Basel Radiolabeled conjugates based on substance P and the uses thereof
JP2009511565A (ja) * 2005-10-14 2009-03-19 スティフティング カトリーケ ユニフェルスィテイト １つ以上の部位特異的に結合体化されたヒドラジノニコチンアミド（ｈｙｎｉｃ）部分を介して標識されたインターロイキン−８、ならびに感染および炎症の診断におけるその使用
US8691761B2 (en) * 2006-10-16 2014-04-08 Jean E. F. Rivier Somatostatin receptor 2 antagonists
CA2666642C (en) 2006-10-16 2015-11-17 The Salk Institute For Biological Studies Receptor(sstr2)-selective somatostatin antagonists
WO2009012288A2 (en) 2007-07-17 2009-01-22 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Trifunctional imaging agent for monoclonal antibody tumor-targeted imaging
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
GB0903496D0 (en) * 2009-02-27 2009-04-08 Cambridge Entpr Ltd Methods for identification
ES2351569B8 (es) 2009-05-07 2012-06-20 Bcn Peptides S.A. Ligandos peptídicos de receptores de somatostatina.
GB0922369D0 (en) * 2009-12-22 2010-02-03 Hammersmith Imanet Ltd Labelled biotin conjugates
CN104768565B (zh) * 2012-11-01 2017-04-26 益普生制药股份有限公司 促生长素抑制素类似物及其二聚体
TWI523863B (zh) 2012-11-01 2016-03-01 艾普森藥品公司 體抑素－多巴胺嵌合體類似物
JP6410339B2 (ja) * 2013-03-25 2018-10-24 国立大学法人千葉大学 放射性核種標識オクトレオチド誘導体
AU2017217271C1 (en) 2016-02-09 2021-08-05 Cdrd Ventures Inc. Somatostatin receptor antagonist compounds and methods of using the same
DK3568205T3 (da) 2017-01-12 2023-10-09 Radiomedix Inc Behandling af cancerceller, der overeksprimerer somatostatinreceptorer ved at anvende radioisotop-chelaterede ocreotid-derivater
CN108440664A (zh) * 2018-03-27 2018-08-24 上海欣科医药有限公司 一种用于癌症检测的生长抑素类似物及其制备方法和应用
CN112538103B (zh) * 2020-12-28 2022-10-25 合肥科生景肽生物科技有限公司 制备生长激素释放抑制素的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5819669B2 (ja) * 1978-10-28 1983-04-19 白井松新薬株式会社 新規生理活性ペプチド化合物及びその製造法
US5620675A (en) * 1992-06-23 1997-04-15 Diatech, Inc. Radioactive peptides
US6051206A (en) * 1994-06-03 2000-04-18 Diatide, Inc Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
US6355613B1 (en) * 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US6180082B1 (en) * 1997-11-24 2001-01-30 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method to enhance tissue accumulation of radiolabeled compounds
US6358491B1 (en) * 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
EP1086947A1 (en) * 1999-09-01 2001-03-28 Pfizer Products Inc. Somatostatin antagonists and agonists that act at the SST subtype 2 receptor
EP1283216A1 (en) 2001-08-10 2003-02-12 Mallinckrodt Inc. Somatostatin analogues binding to all somatostatin receptor subtypes and their use

Also Published As

Publication number Publication date
US20040242842A1 (en) 2004-12-02
AU2002333396B2 (en) 2008-05-22
ATE328005T1 (de) 2006-06-15
EP1419178A1 (en) 2004-05-19
DE60211917D1 (de) 2006-07-06
JP2005508886A (ja) 2005-04-07
EP1283216A1 (en) 2003-02-12
PT1419178E (pt) 2006-09-29
US7541018B2 (en) 2009-06-02
US7192570B2 (en) 2007-03-20
DE60211917T2 (de) 2007-01-18
WO2003014158A1 (en) 2003-02-20
DK1419178T3 (da) 2006-10-02
US20070154392A1 (en) 2007-07-05
CA2456881A1 (en) 2003-02-20
CY1105177T1 (el) 2010-03-03
EP1419178B1 (en) 2006-05-31

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