ES2266515T3 - Cepa de lactococcus con autocontencion. - Google Patents
Cepa de lactococcus con autocontencion. Download PDFInfo
- Publication number
- ES2266515T3 ES2266515T3 ES02740565T ES02740565T ES2266515T3 ES 2266515 T3 ES2266515 T3 ES 2266515T3 ES 02740565 T ES02740565 T ES 02740565T ES 02740565 T ES02740565 T ES 02740565T ES 2266515 T3 ES2266515 T3 ES 2266515T3
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- lactococcus
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- C12N9/10—Transferases (2.)
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C12Y—ENZYMES
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01201631 | 2001-05-03 | ||
| EP01201631 | 2001-05-03 | ||
| EP01204785 | 2001-12-07 | ||
| EP01204785 | 2001-12-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2266515T3 true ES2266515T3 (es) | 2007-03-01 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02740565T Expired - Lifetime ES2266515T3 (es) | 2001-05-03 | 2002-05-03 | Cepa de lactococcus con autocontencion. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1383897B1 (https=) |
| JP (2) | JP4347575B2 (https=) |
| AT (1) | ATE331789T1 (https=) |
| AU (1) | AU2002314040B2 (https=) |
| CA (1) | CA2446776C (https=) |
| DE (1) | DE60212825T2 (https=) |
| DK (1) | DK1383897T3 (https=) |
| ES (1) | ES2266515T3 (https=) |
| WO (1) | WO2002090551A2 (https=) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7780961B2 (en) | 2001-05-03 | 2010-08-24 | Actogenix N.V. | Self-containing Lactococcus strain |
| DE60319822T2 (de) | 2002-06-19 | 2009-06-04 | Actogenix Nv | Verfahren und mittel zur erhöhung der darmabsorption |
| WO2004056850A2 (en) * | 2002-12-19 | 2004-07-08 | Vib Vzw | Mutant proteins showing increased secretion |
| JP4589618B2 (ja) * | 2003-11-28 | 2010-12-01 | 独立行政法人農業生物資源研究所 | 免疫調節性機能を誘導する乳酸菌類とその成分 |
| ES2439698T3 (es) | 2004-08-20 | 2014-01-24 | Actogenix N.V. | Procedimiento para mejorar la conservación de lactococos |
| AU2006319216B2 (en) * | 2005-11-29 | 2012-09-13 | Intrexon Actobiotics Nv | Induction of mucosal tolerance to antigens |
| JP2010513245A (ja) * | 2006-12-14 | 2010-04-30 | アクトジェニックス・エヌブイ | 免疫調節を誘起するための結合分子の送達 |
| EP2115146B1 (en) * | 2007-01-12 | 2016-07-06 | Intrexon Actobiotics NV | Lactococcus promoters and uses thereof |
| CN103933563B (zh) | 2007-01-25 | 2016-09-28 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 使用遗传修饰的乳杆菌通过抗原的粘膜递送治疗免疫疾病 |
| DK3181682T3 (da) * | 2008-09-29 | 2021-07-05 | Intrexon Actobiotics Nv | Reduceret kolonisering af mikrober på slimhinden |
| WO2012164083A1 (en) | 2011-06-01 | 2012-12-06 | Actogenix N.V. | Polycistronic expression system for bacteria |
| WO2013041672A1 (en) | 2011-09-23 | 2013-03-28 | Actogenix Nv | Modified gram positive bacteria and uses thereof |
| EP3382006B1 (en) | 2011-09-23 | 2021-02-17 | Intrexon Actobiotics NV | Modified gram positive bacteria and uses thereof |
| US9688967B2 (en) | 2014-12-05 | 2017-06-27 | Synlogic, Inc. | Bacteria engineered to treat diseases associated with hyperammonemia |
| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| BR112017018656B1 (pt) * | 2015-03-02 | 2021-11-30 | Synlogic, Inc | Bactéria geneticamente modificada, composição farmaceuticamente aceitável compreendendo a dita bactéria e uso da dita composição para tratar ou prevenir uma doença ou condição associada à inflamação intestinal e/ou função da barreira intestinal comprometida |
| CN106148254B (zh) * | 2015-03-26 | 2019-11-12 | 南京华贞生物医药科技有限公司 | 一种用于减肥降脂的转化体及其构建方法与应用 |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| WO2017087580A1 (en) | 2015-11-16 | 2017-05-26 | Synlogic, Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| CA3011331C (en) | 2016-01-14 | 2025-05-13 | Intrexon Actobiotics N.V. | Compositions and methods for the treatment of type 1 diabetes |
| JP7016865B2 (ja) | 2016-09-02 | 2022-03-03 | イントレクソン・アクトバイオテイクス・エヌブイ | Ｉｌ－１０およびインスリンを安定的に発現する遺伝子改変された細菌 |
| CN109983028B (zh) | 2016-09-13 | 2023-10-20 | 英特瑞克斯顿阿克图比奥帝克斯有限公司 | 黏膜黏附性微生物 |
| CN111655841A (zh) | 2017-06-21 | 2020-09-11 | 同生运营公司 | 用于治疗紊乱的细菌 |
| US20210393711A1 (en) | 2018-10-11 | 2021-12-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Bacteria expressing single chain antibodies against toll-like receptors |
| CA3156035A1 (en) | 2019-09-27 | 2021-04-01 | Intrexon Actobiotics Nv D/B/A Precigen Actobio | Treatment of celiac disease |
| CN115298308A (zh) | 2020-03-20 | 2022-11-04 | 同生运营公司 | 经工程化以减轻高苯丙氨酸血症的微生物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4231764A1 (de) * | 1992-09-23 | 1994-03-24 | Inst Pflanzengenetik & Kultur | Verfahren zur chromosomalen Integration eines Produkt-Gens |
-
2002
- 2002-05-03 WO PCT/EP2002/004942 patent/WO2002090551A2/en not_active Ceased
- 2002-05-03 JP JP2002587611A patent/JP4347575B2/ja not_active Expired - Fee Related
- 2002-05-03 CA CA2446776A patent/CA2446776C/en not_active Expired - Fee Related
- 2002-05-03 AU AU2002314040A patent/AU2002314040B2/en not_active Ceased
- 2002-05-03 EP EP02740565A patent/EP1383897B1/en not_active Expired - Lifetime
- 2002-05-03 AT AT02740565T patent/ATE331789T1/de active
- 2002-05-03 DK DK02740565T patent/DK1383897T3/da active
- 2002-05-03 ES ES02740565T patent/ES2266515T3/es not_active Expired - Lifetime
- 2002-05-03 DE DE60212825T patent/DE60212825T2/de not_active Expired - Lifetime
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2008
- 2008-10-07 JP JP2008260591A patent/JP2009060913A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002090551A2 (en) | 2002-11-14 |
| ATE331789T1 (de) | 2006-07-15 |
| CA2446776C (en) | 2011-07-12 |
| JP2009060913A (ja) | 2009-03-26 |
| JP4347575B2 (ja) | 2009-10-21 |
| AU2002314040B2 (en) | 2007-06-28 |
| DK1383897T3 (da) | 2006-10-30 |
| EP1383897A2 (en) | 2004-01-28 |
| WO2002090551A3 (en) | 2003-03-27 |
| JP2004533246A (ja) | 2004-11-04 |
| DE60212825D1 (de) | 2006-08-10 |
| CA2446776A1 (en) | 2002-11-14 |
| DE60212825T2 (de) | 2007-01-11 |
| EP1383897B1 (en) | 2006-06-28 |
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