ES2258981T3 - Uso de aminoacidos sencillos para formar particulas porosas. - Google Patents
Uso de aminoacidos sencillos para formar particulas porosas.Info
- Publication number
- ES2258981T3 ES2258981T3 ES00957716T ES00957716T ES2258981T3 ES 2258981 T3 ES2258981 T3 ES 2258981T3 ES 00957716 T ES00957716 T ES 00957716T ES 00957716 T ES00957716 T ES 00957716T ES 2258981 T3 ES2258981 T3 ES 2258981T3
- Authority
- ES
- Spain
- Prior art keywords
- particles
- diameter
- therapeutic
- amino acid
- amino acids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0082—Lung surfactant, artificial mucus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/382,959 US6586008B1 (en) | 1999-08-25 | 1999-08-25 | Use of simple amino acids to form porous particles during spray drying |
| US382959 | 1999-08-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2258981T3 true ES2258981T3 (es) | 2006-09-16 |
Family
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Family Applications (1)
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| ES00957716T Expired - Lifetime ES2258981T3 (es) | 1999-08-25 | 2000-08-23 | Uso de aminoacidos sencillos para formar particulas porosas. |
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| ES (1) | ES2258981T3 (enExample) |
| PT (1) | PT1210068E (enExample) |
| WO (1) | WO2001013893A2 (enExample) |
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1999
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2000
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- 2000-08-23 DK DK00957716T patent/DK1210068T3/da active
- 2000-08-23 EP EP05077639A patent/EP1637128A3/en not_active Withdrawn
- 2000-08-23 ES ES00957716T patent/ES2258981T3/es not_active Expired - Lifetime
- 2000-08-23 WO PCT/US2000/023149 patent/WO2001013893A2/en not_active Ceased
- 2000-08-23 PT PT00957716T patent/PT1210068E/pt unknown
- 2000-08-23 CA CA002382651A patent/CA2382651C/en not_active Expired - Lifetime
- 2000-08-23 DE DE60026544T patent/DE60026544T2/de not_active Expired - Lifetime
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2006
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2007
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- 2007-10-17 US US11/873,472 patent/US20080160098A1/en not_active Abandoned
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2011
- 2011-01-20 US US13/010,032 patent/US8268358B2/en not_active Expired - Fee Related
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2012
- 2012-08-17 US US13/588,549 patent/US9333174B2/en not_active Expired - Fee Related
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2016
- 2016-04-07 US US15/092,799 patent/US20160287517A1/en not_active Abandoned
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2017
- 2017-01-26 US US15/416,328 patent/US20170354602A1/en not_active Abandoned
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| US20070104658A1 (en) | 2007-05-10 |
| US20160287517A1 (en) | 2016-10-06 |
| US8268358B2 (en) | 2012-09-18 |
| PT1210068E (pt) | 2006-07-31 |
| ATE319429T1 (de) | 2006-03-15 |
| US20080160098A1 (en) | 2008-07-03 |
| CA2382651A1 (en) | 2001-03-01 |
| EP1210068A2 (en) | 2002-06-05 |
| JP2003507412A (ja) | 2003-02-25 |
| WO2001013893A2 (en) | 2001-03-01 |
| DE60026544T2 (de) | 2007-01-11 |
| US20080160092A1 (en) | 2008-07-03 |
| US20170354602A1 (en) | 2017-12-14 |
| EP1637128A3 (en) | 2008-03-05 |
| US6586008B1 (en) | 2003-07-01 |
| US9333174B2 (en) | 2016-05-10 |
| US20130071440A1 (en) | 2013-03-21 |
| EP1210068B1 (en) | 2006-03-08 |
| DE60026544D1 (de) | 2006-05-04 |
| CA2382651C (en) | 2009-11-24 |
| WO2001013893A3 (en) | 2001-05-03 |
| US20120020887A1 (en) | 2012-01-26 |
| EP1637128A2 (en) | 2006-03-22 |
| AU764738B2 (en) | 2003-08-28 |
| DK1210068T3 (da) | 2006-07-17 |
| AU6929600A (en) | 2001-03-19 |
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