ES2253763T3 - Metodo para la estabilizacion de plaquetas. - Google Patents
Metodo para la estabilizacion de plaquetas.Info
- Publication number
- ES2253763T3 ES2253763T3 ES97112828T ES97112828T ES2253763T3 ES 2253763 T3 ES2253763 T3 ES 2253763T3 ES 97112828 T ES97112828 T ES 97112828T ES 97112828 T ES97112828 T ES 97112828T ES 2253763 T3 ES2253763 T3 ES 2253763T3
- Authority
- ES
- Spain
- Prior art keywords
- liter
- platelets
- concentration
- platelets according
- around
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2496/00—Reference solutions for assays of biological material
- G01N2496/05—Reference solutions for assays of biological material containing blood cells or plasma
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Developmental Biology & Embryology (AREA)
- Diabetes (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19634313 | 1996-08-24 | ||
DE19634313A DE19634313A1 (de) | 1996-08-24 | 1996-08-24 | Methode zur Stabilisierung von Plättchen |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2253763T3 true ES2253763T3 (es) | 2006-06-01 |
Family
ID=7803631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97112828T Expired - Lifetime ES2253763T3 (es) | 1996-08-24 | 1997-07-25 | Metodo para la estabilizacion de plaquetas. |
Country Status (7)
Country | Link |
---|---|
US (2) | US6127111A (de) |
EP (1) | EP0826966B1 (de) |
JP (1) | JP4283905B2 (de) |
AT (1) | ATE317127T1 (de) |
CA (1) | CA2213721C (de) |
DE (2) | DE19634313A1 (de) |
ES (1) | ES2253763T3 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19634313A1 (de) * | 1996-08-24 | 1998-02-26 | Behringwerke Ag | Methode zur Stabilisierung von Plättchen |
DE50014159D1 (de) * | 1999-12-22 | 2007-04-26 | Dade Behring Marburg Gmbh | Lösungen von humanem Procalcitonin |
DE19964109A1 (de) | 1999-12-29 | 2001-07-05 | Dade Behring Marburg Gmbh | Gebrauchsfertiges langzeitstabiles Ristocetin Cofaktor Testreagenz |
EP1736051A3 (de) * | 2005-06-22 | 2010-03-17 | Cheng-Yao Su | Mittels und Verfahren zur Preservierung vom Blutplättchen, Blutkörperchen, und andere Kernlose Zellen und Blutplättchen-enthaltende Zusammensetzung |
AU2006294654B2 (en) * | 2005-09-26 | 2012-05-24 | Lifecell Corporation | Dry platelet composition |
US8440695B2 (en) * | 2005-11-09 | 2013-05-14 | St Jude Children's Research Hospital | Use of chloroquine to treat metabolic syndrome |
JP2007197353A (ja) * | 2006-01-25 | 2007-08-09 | Univ Of Tsukuba | 肝再生促進剤 |
KR101067443B1 (ko) * | 2009-06-23 | 2011-09-27 | 여오영 | 하이드록시클로로퀸을 함유하는 치핵 치료를 위한 국소투여용 주사제 조성물 |
EP2508892A1 (de) * | 2011-04-04 | 2012-10-10 | Siemens Healthcare Diagnostics Products GmbH | Kontrollen und Kit für Thrombozytenaktivitätsteste |
JP5559096B2 (ja) * | 2011-05-10 | 2014-07-23 | 株式会社堀場製作所 | 血球計数用試薬、及び血液検査方法 |
JP6875619B2 (ja) * | 2015-02-26 | 2021-05-26 | 株式会社細胞応用技術研究所 | 多血小板血漿の保存方法 |
RU2664478C2 (ru) * | 2017-08-18 | 2018-08-17 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) | Способ получения культуральной ростовой добавки на основе лизата тромбоцитов человека |
JP7110360B2 (ja) | 2017-10-09 | 2022-08-01 | テルモ ビーシーティー バイオテクノロジーズ,エルエルシー | 凍結乾燥方法 |
US20200224164A1 (en) | 2018-11-30 | 2020-07-16 | Cellphire, Inc. | Platelets as delivery agents |
US11767511B2 (en) | 2018-11-30 | 2023-09-26 | Cellphire, Inc. | Platelets as delivery agents |
CA3130700A1 (en) | 2019-03-14 | 2020-09-17 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
EP3962499A4 (de) | 2019-05-03 | 2023-01-25 | Cellphire Inc. | Materialien und verfahren zur herstellung von blutprodukten |
WO2021034719A1 (en) | 2019-08-16 | 2021-02-25 | Cellphire, Inc. | Thrombosomes as an antiplatelet agent reversal agent |
CA3170196A1 (en) | 2020-02-04 | 2021-08-12 | Cellphire, Inc. | Anti-fibrinolytic loaded platelets |
US20230416786A1 (en) | 2020-11-30 | 2023-12-28 | Cellectis Sa | Use of aminoquinoline compounds for higher gene integration |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1074698A (en) * | 1977-12-19 | 1980-04-01 | Gail A. Rock | Method of collecting anti-hemophilic factor viii from blood and blood plasma |
US4405719A (en) * | 1981-05-29 | 1983-09-20 | Coulter Electronics, Inc. | Method of stabilizing platelets for determining multiple platelet parameters in reference control and calibrator compositions; diluents therefor; and combination stabilization procedures |
JPH0723311B2 (ja) * | 1985-04-25 | 1995-03-15 | 日本クリニツク株式会社 | 血小板凝集抑制剤 |
US4695460A (en) * | 1986-03-19 | 1987-09-22 | American Red Cross | Synthetic, plasma-free, transfusible platelet storage medium |
US5213814A (en) * | 1989-04-10 | 1993-05-25 | Cryopharm Corporation | Lyophilized and reconstituted blood platelet compositions |
DE3942081A1 (de) * | 1989-12-20 | 1991-06-27 | Behringwerke Ag | Mittel zur verbesserung der wiederfindung von annexinen |
CA2075928A1 (en) * | 1991-01-11 | 1992-07-12 | Roger W. Hackett | Method of detecting circulating antibody types using dried or lyophilized cells or cell-like material |
AU672775B2 (en) * | 1992-01-21 | 1996-10-17 | Cobe Laboratories Inc. | Method of freezing cells and cell-like materials |
DE69332756T2 (de) * | 1992-05-29 | 2004-02-19 | University Of North Carolina At Chapel Hill | Im immobilisierten zustand getrocknete pharmazeutische verträgliche menschliche blutplättchen |
CN1091315A (zh) * | 1992-10-08 | 1994-08-31 | E·R·斯奎布父子公司 | 血纤维蛋白封闭剂组合物及其使用方法 |
JP3788522B2 (ja) * | 1994-02-22 | 2006-06-21 | 日本電信電話株式会社 | 血球、幹細胞、および血小板の凍結乾燥生成物の製造方法 |
US5622867A (en) * | 1994-10-19 | 1997-04-22 | Lifecell Corporation | Prolonged preservation of blood platelets |
US5736313A (en) * | 1995-10-20 | 1998-04-07 | The United States Of America As Represented By The Secretary Of The Navy | Method of lyophilizing platelets by incubation with high carbohydrate concentrations and supercooling prior to freezing |
DE19634313A1 (de) * | 1996-08-24 | 1998-02-26 | Behringwerke Ag | Methode zur Stabilisierung von Plättchen |
-
1996
- 1996-08-24 DE DE19634313A patent/DE19634313A1/de not_active Ceased
-
1997
- 1997-07-25 ES ES97112828T patent/ES2253763T3/es not_active Expired - Lifetime
- 1997-07-25 DE DE59712562T patent/DE59712562D1/de not_active Expired - Lifetime
- 1997-07-25 EP EP97112828A patent/EP0826966B1/de not_active Expired - Lifetime
- 1997-07-25 AT AT97112828T patent/ATE317127T1/de active
- 1997-08-21 US US08/915,558 patent/US6127111A/en not_active Expired - Lifetime
- 1997-08-22 CA CA2213721A patent/CA2213721C/en not_active Expired - Fee Related
- 1997-08-22 JP JP22595397A patent/JP4283905B2/ja not_active Expired - Lifetime
-
2000
- 2000-06-07 US US09/588,497 patent/US6372423B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE19634313A1 (de) | 1998-02-26 |
US6127111A (en) | 2000-10-03 |
CA2213721A1 (en) | 1998-02-24 |
US6372423B1 (en) | 2002-04-16 |
JP4283905B2 (ja) | 2009-06-24 |
EP0826966A3 (de) | 1999-03-03 |
JPH1067667A (ja) | 1998-03-10 |
ATE317127T1 (de) | 2006-02-15 |
DE59712562D1 (de) | 2006-04-13 |
EP0826966A2 (de) | 1998-03-04 |
EP0826966B1 (de) | 2006-02-01 |
CA2213721C (en) | 2010-04-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2253763T3 (es) | Metodo para la estabilizacion de plaquetas. | |
Wachtfogel et al. | Human neutrophil degranulation during extracorporeal circulation | |
Beer et al. | Glycocalicin: a new assay--the normal plasma levels and its potential usefulness in selected diseases | |
Colvin et al. | Fibrinogen/fibrin on the surface of macrophages: detection, distribution, binding requirements, and possible role in macrophage adherence phenomena. | |
Katz et al. | Relationship between human development and disappearance of unusually large von Willebrand factor multimers from plasma | |
US4994367A (en) | Extended shelf life platelet preparations and process for preparing the same | |
Das et al. | Clearance of endotoxin by platelets: role in increasing the accuracy of the Limulus gelation test and in combating experimental endotoxemia | |
JP3038006B2 (ja) | 敗血症または敗血症ショックの処置または予防のための組成物および方法 | |
Agam et al. | Erythrocytes with covalently bound fibrinogen as a cellular replacement for the treatment of thrombocytopenia | |
Kumada et al. | Comparative study on heparin and a synthetic thrombin inhibitor No. 805 (MD-805) in experimental antithrombin III-deficient animals | |
Rapaport et al. | The blood clotting properties of rabbit peritoneal leukocytes in vitro | |
Prowse et al. | Studies on the procurement of blood coagulation factor VIII in vitro studies on blood components prepared in half‐strength citrate anticoagulant | |
ES2285734T3 (es) | Multimerasa purificada. | |
Takahashi et al. | Further characterization of platelet-type von Willebrand's disease in Japan | |
Böhmig | The coagulation disorder of orthotopic hepatic transplantation | |
Niemetz | The role of protein synthesis on the generation of tissue factor activity by leukocytes | |
Mannucci et al. | A new variant of type II von Willebrand disease with aberrant multimeric structure of plasma but not platelet von Willebrand factor (type IIF) | |
Mezzano et al. | Changes in platelet β‐thromboglobulin, fibrinogen, albumin, 5‐hydroxytryptamine, ATP, and ADP during and after surgery with extracorporeal circulation in man | |
Aronson | Factor VIII (antihemophilic globulin) | |
Karpman et al. | Increased platelet retention in familial recurrent thrombotic thrombocytopenic purpura | |
Monteagudo et al. | Investigation of plasma von Willebrand factor and circulating platelet aggregating activity in mitomycin C‐related hemolytic‐uremic syndrome | |
Maurer et al. | Influence of bilirubin on human platelets | |
Niklasson et al. | Thrombocytopenia and bleeding complications in severe cases of meningococcal infection treated with heparin, dextran 70 and chlorpromazine | |
Dulock et al. | Influence of vitamin K on restoration of prothrombin complex proteins and fibrinogen in plasma of depleted dogs | |
Astrup et al. | Serum effects following tissue thromboplastin infusion |