ES2249058T3 - Factores de preservacion de celulas progenitoras y metodos y productos relacionados. - Google Patents

Factores de preservacion de celulas progenitoras y metodos y productos relacionados.

Info

Publication number
ES2249058T3
ES2249058T3 ES99967798T ES99967798T ES2249058T3 ES 2249058 T3 ES2249058 T3 ES 2249058T3 ES 99967798 T ES99967798 T ES 99967798T ES 99967798 T ES99967798 T ES 99967798T ES 2249058 T3 ES2249058 T3 ES 2249058T3
Authority
ES
Spain
Prior art keywords
cells
fril family
progeniting
products
family members
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES99967798T
Other languages
English (en)
Inventor
M Gabriella Colucci
Maarten J Chrispeels
Jeffrey G Moore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
ImClone LLC
Original Assignee
University of California
ImClone Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California, ImClone Systems Inc filed Critical University of California
Application granted granted Critical
Publication of ES2249058T3 publication Critical patent/ES2249058T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C07K14/42—Lectins, e.g. concanavalin, phytohaemagglutinin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Utilización de una cantidad terapéuticamente eficaz de una composición que contiene una proteína FRIL que comprende la secuencia de aminoácidos presentada en la SEC ID nº 6 para la preparación de un medicamento destinado al tratamiento de un estado caracterizada por la actividad deplecionadora de las células progenitoras hematopoyéticas de un tratamiento quimioterapéutico o radioterapéutico o una combinación de un tratamiento quimioterapéutico y radioterapéutico, en la que la cantidad terapéuticamente eficaz de dicha composición alivia o reduce la actividad deplecionadora de las células progenitoras hematopoyéticas de dicho tratamiento en el paciente y en la que el medicamento se debe administrar antes del tratamiento radioterapéutico o quimioterapéutico; en la que el medicamento se debe administrar aproximadamente entre 5 días y aproximadamente 2 horas antes del tratamiento quimioterapéutico o radioterapéutico y se debe administrar diariamente.
ES99967798T 1999-12-30 1999-12-30 Factores de preservacion de celulas progenitoras y metodos y productos relacionados. Expired - Lifetime ES2249058T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/031307 WO2001049851A1 (en) 1999-12-30 1999-12-30 Progenitor cell preservation factors and related methods and products

Publications (1)

Publication Number Publication Date
ES2249058T3 true ES2249058T3 (es) 2006-03-16

Family

ID=22274423

Family Applications (1)

Application Number Title Priority Date Filing Date
ES99967798T Expired - Lifetime ES2249058T3 (es) 1999-12-30 1999-12-30 Factores de preservacion de celulas progenitoras y metodos y productos relacionados.

Country Status (10)

Country Link
EP (1) EP1246919B1 (es)
JP (1) JP2003521900A (es)
CN (1) CN1406280A (es)
AT (1) ATE302848T1 (es)
AU (1) AU784361C (es)
CA (1) CA2395625A1 (es)
DE (1) DE69926920T2 (es)
ES (1) ES2249058T3 (es)
HK (1) HK1050027B (es)
WO (1) WO2001049851A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020132017A1 (en) 1996-12-09 2002-09-19 Moore Jeffrey G. Composition and method for preserving progenitor cells
KR100951409B1 (ko) 2001-01-09 2010-04-07 베일러 리서치 인스티튜트 수지상 세포로의 단핵세포 분화를 억제하는 조성물 및 이를 포함하는 키트
CA2439297A1 (en) * 2001-02-27 2002-09-06 Phylogix Llc Compositions and methods for protecting tissues and cells from damage, and for repairing damaged tissues
CN101415434A (zh) * 2003-11-12 2009-04-22 晨兴风险投资有限公司 用于治疗b细胞淋巴瘤和其它癌症的方法和组合物
CA2604007A1 (en) * 2005-04-08 2006-10-19 Morningside Venture Investments Limited Use of fril proteins for reducing the production of pro-inflammatory cytokines
JP2010516239A (ja) 2007-01-18 2010-05-20 スオメン プナイネン リスティ，ヴェリパルベル 細胞の産生に対する新規方法および試薬
DK2173859T3 (en) 2007-06-29 2016-08-22 Makoto Funaki Soft-gel systems for the modulation of stem cell development
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
JP6247472B2 (ja) * 2013-08-06 2017-12-13 日本メナード化粧品株式会社 幹細胞の未分化状態維持剤及び増殖促進剤
EP3068867B1 (en) 2013-11-16 2018-04-18 Terumo BCT, Inc. Expanding cells in a bioreactor
WO2015148704A1 (en) 2014-03-25 2015-10-01 Terumo Bct, Inc. Passive replacement of media
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
JP2024511064A (ja) 2021-03-23 2024-03-12 テルモ ビーシーティー、インコーポレーテッド 細胞捕獲及び増殖
CN114262683B (zh) * 2022-03-01 2022-06-17 中国科学院动物研究所 一种表达vegfr3 d2多肽的细菌制剂及其构建方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6455678B1 (en) * 1996-04-26 2002-09-24 Amcell Corporation Human hematopoietic stem and progenitor cell antigen
US6084060A (en) * 1996-12-09 2000-07-04 Imclone Systems Incorporated Composition and method for preserving progenitor cells
US6310195B1 (en) * 1997-06-24 2001-10-30 Imclone Systems Incorporated Nucleic acid encoding a lectin-derived progenitor cell preservation factor

Also Published As

Publication number Publication date
CN1406280A (zh) 2003-03-26
CA2395625A1 (en) 2001-07-12
HK1050027A1 (en) 2003-06-06
EP1246919A1 (en) 2002-10-09
DE69926920D1 (de) 2005-09-29
JP2003521900A (ja) 2003-07-22
AU2401400A (en) 2001-07-16
AU784361B2 (en) 2006-03-16
ATE302848T1 (de) 2005-09-15
AU784361C (en) 2007-03-15
DE69926920T2 (de) 2006-06-29
HK1050027B (zh) 2006-04-13
WO2001049851A1 (en) 2001-07-12
EP1246919B1 (en) 2005-08-24

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