ES2240740T3 - Metodo para proporcionar latencia a agentes farmaceuticamente activos. - Google Patents
Metodo para proporcionar latencia a agentes farmaceuticamente activos.Info
- Publication number
- ES2240740T3 ES2240740T3 ES02729440T ES02729440T ES2240740T3 ES 2240740 T3 ES2240740 T3 ES 2240740T3 ES 02729440 T ES02729440 T ES 02729440T ES 02729440 T ES02729440 T ES 02729440T ES 2240740 T3 ES2240740 T3 ES 2240740T3
- Authority
- ES
- Spain
- Prior art keywords
- protein
- lap
- nucleic acid
- fusion protein
- mmp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/756,283 US6942853B2 (en) | 2001-01-09 | 2001-01-09 | Latent fusion protein |
| GB0100551 | 2001-01-09 | ||
| GBGB0100551.1A GB0100551D0 (en) | 2001-01-09 | 2001-01-09 | Protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2240740T3 true ES2240740T3 (es) | 2005-10-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES02729440T Expired - Lifetime ES2240740T3 (es) | 2001-01-09 | 2002-01-09 | Metodo para proporcionar latencia a agentes farmaceuticamente activos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6942853B2 (enExample) |
| EP (1) | EP1349944B1 (enExample) |
| JP (1) | JP4201253B2 (enExample) |
| AT (1) | ATE293169T1 (enExample) |
| AU (1) | AU2002219345B2 (enExample) |
| DE (1) | DE60203692T2 (enExample) |
| DK (1) | DK1349944T3 (enExample) |
| ES (1) | ES2240740T3 (enExample) |
| GB (1) | GB0100551D0 (enExample) |
| WO (1) | WO2002055098A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141392B2 (en) * | 2001-01-09 | 2006-11-28 | Queen Mary And Westfield College | Latent fusion protein |
| AU2003217415B2 (en) * | 2002-02-14 | 2009-01-08 | William J Rutter | Chimeric molecules for cleavage in a treated host |
| AU2006302587A1 (en) * | 2005-10-04 | 2007-04-19 | Greenville Hospital System | Latent procytotoxins and uses thereof |
| DE102006009324A1 (de) | 2006-03-01 | 2007-09-06 | Dr.Ing.H.C. F. Porsche Ag | Verfahren und Steuergerät zur Steuerung eines variablen Turbolader-Turbinenströmungsquerschnitts |
| EP2572734B1 (en) | 2006-10-31 | 2016-04-06 | East Carolina University | Cytokine-based fusion proteins for treatment of immune disorders |
| GB0724556D0 (en) * | 2007-12-17 | 2008-01-30 | Queen Mary & Westfield College | LAtency associated protein construct with aggrecanase sensitive cleavage site |
| FR2932190A1 (fr) * | 2008-06-10 | 2009-12-11 | Commissariat Energie Atomique | Peptides cycliques fluorescents, procedes de preparation de ceux-ci et utilisation de ces peptides pour mesurer l'activite enzymatique d'une enzyme protease |
| EP3348275A3 (en) | 2009-03-31 | 2018-10-24 | East Carolina University | Cytokines and neuroantigens for treatment of immune disorders |
| GB0911365D0 (en) | 2009-06-30 | 2009-08-12 | Bioceramic Therapeutics Ltd | Multicomponent glasses for use as coatings and in personal care products |
| US8734774B2 (en) | 2010-04-02 | 2014-05-27 | University Of Rochester | Protease activated cytokines |
| EP2878308B1 (en) * | 2013-12-02 | 2018-10-31 | Thomas Harder | Agents and methods for the suppression of T cell activation |
| GB201411506D0 (en) * | 2014-06-27 | 2014-08-13 | Univ London Queen Mary | Modified latency associated protein construct |
| JP6516235B2 (ja) * | 2014-10-31 | 2019-05-22 | 国立大学法人富山大学 | キメラタンパク質及びそれを用いたミクログリア活性阻害剤 |
| CN113840832A (zh) | 2018-05-14 | 2021-12-24 | 狼人治疗公司 | 可活化白介素-2多肽及其使用方法 |
| MX2020012252A (es) | 2018-05-14 | 2021-04-28 | Werewolf Therapeutics Inc | Polipeptidos de interleucina 12 activables y metodos de uso de los mismos. |
| US12459980B2 (en) | 2018-07-25 | 2025-11-04 | AskGene Pharma, Inc. | IL-21 prodrugs and methods of use thereof |
| KR20250154552A (ko) * | 2018-09-27 | 2025-10-28 | 실리오 디벨럽먼트, 인크. | 마스킹된 사이토카인 폴리펩타이드 |
| ES2780274A1 (es) * | 2019-02-15 | 2020-08-24 | Consejo Superior De Investig Científicas (Csic) | Cortistatina o un análogo de la misma como agente farmacéuticamente activo en forma latente |
| EP3969035A4 (en) | 2019-05-14 | 2023-06-21 | Werewolf Therapeutics, Inc. | SEPARATION UNITS AND METHODS AND THEIR USE |
| WO2020252264A1 (en) | 2019-06-12 | 2020-12-17 | AskGene Pharma, Inc. | Novel il-15 prodrugs and methods of use thereof |
| WO2021097376A1 (en) | 2019-11-14 | 2021-05-20 | Werewolf Therapeutics, Inc. | Activatable cytokine polypeptides and methods of use thereof |
| GB202004679D0 (en) | 2020-03-31 | 2020-05-13 | Stealthyx Therapeutics Ltd | Modified latercy associated protein construct |
| CN115667523A (zh) * | 2020-04-10 | 2023-01-31 | 西托姆克斯治疗公司 | 可活化细胞因子构建体和相关组合物以及方法 |
| EP4251187A4 (en) | 2020-11-25 | 2025-09-10 | Xilio Dev Inc | TUMOR-SPECIFIC CLASSIBLE LINKERS |
| KR20230157448A (ko) | 2021-03-16 | 2023-11-16 | 싸이톰스 테라퓨틱스, 인크. | 마스킹된 활성화 가능한 사이토카인 작제물 및 관련 조성물 및 방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284763A (en) | 1985-03-22 | 1994-02-08 | Genentech, Inc. | Nucleic acid encoding TGF-β and its uses |
| CA2003886A1 (en) | 1988-12-16 | 1990-06-16 | Anthony F. Purchio | Cloning and expression of simian transforming growth factor-beta 1 |
| CA2068204C (en) | 1989-11-22 | 2002-02-12 | Arthur Levinson | Latency associated peptides and uses therefor |
| US5697901A (en) | 1989-12-14 | 1997-12-16 | Elof Eriksson | Gene delivery by microneedle injection |
| PT698094E (pt) | 1993-05-12 | 2004-05-31 | Inst Genetics Llc | Composicoes de bmp-11 |
| CA2151547C (en) | 1994-06-10 | 2010-10-12 | Elliott A. Gruskin | Recombinant chimeric proteins and methods of use thereof |
| US5800811A (en) * | 1995-06-06 | 1998-09-01 | Hall; Frederick L. | Artificial skin prepared from coclagen matrix containing transforming growth factor-β having a collagen binding site |
| WO1997012048A1 (en) * | 1995-09-27 | 1997-04-03 | Medical Research Council | Recombinant viruses incorporating a protease cleavable protein |
| DE19701141C1 (de) | 1997-01-16 | 1998-04-09 | Hoechst Ag | Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen |
| JP4566290B2 (ja) * | 1997-04-30 | 2010-10-20 | ツインストランド・ホールディングス・インコーポレイテッド | 癌、ウイルスまたは寄生虫感染を治療するためのリシン様毒素変異体 |
| GB2324960A (en) | 1997-05-09 | 1998-11-11 | Univ Manchester | Delivery of naked DNA for wound healing |
| AU1103900A (en) | 1998-10-07 | 2000-04-26 | Stryker Corporation | Modified tgf-beta superfamily proteins |
| AU8911101A (en) * | 2000-09-11 | 2002-03-26 | Univ Columbia | Combinatorial fluorescence energy transfer tags and uses thereof |
-
2001
- 2001-01-09 US US09/756,283 patent/US6942853B2/en not_active Expired - Lifetime
- 2001-01-09 GB GBGB0100551.1A patent/GB0100551D0/en not_active Ceased
-
2002
- 2002-01-09 DK DK02729440T patent/DK1349944T3/da active
- 2002-01-09 JP JP2002555832A patent/JP4201253B2/ja not_active Expired - Fee Related
- 2002-01-09 WO PCT/GB2002/000068 patent/WO2002055098A2/en not_active Ceased
- 2002-01-09 AT AT02729440T patent/ATE293169T1/de not_active IP Right Cessation
- 2002-01-09 ES ES02729440T patent/ES2240740T3/es not_active Expired - Lifetime
- 2002-01-09 DE DE60203692T patent/DE60203692T2/de not_active Expired - Lifetime
- 2002-01-09 AU AU2002219345A patent/AU2002219345B2/en not_active Ceased
- 2002-01-09 EP EP02729440A patent/EP1349944B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4201253B2 (ja) | 2008-12-24 |
| EP1349944A2 (en) | 2003-10-08 |
| AU2002219345B2 (en) | 2006-03-16 |
| US6942853B2 (en) | 2005-09-13 |
| JP2004520031A (ja) | 2004-07-08 |
| DK1349944T3 (da) | 2005-07-25 |
| WO2002055098A3 (en) | 2002-11-21 |
| DE60203692T2 (de) | 2006-03-02 |
| DE60203692D1 (de) | 2005-05-19 |
| GB0100551D0 (en) | 2001-02-21 |
| EP1349944B1 (en) | 2005-04-13 |
| WO2002055098A2 (en) | 2002-07-18 |
| US20020151478A1 (en) | 2002-10-17 |
| ATE293169T1 (de) | 2005-04-15 |
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