ES2195016T3 - Medicamento contra la trombocitopenia. - Google Patents
Medicamento contra la trombocitopenia.Info
- Publication number
- ES2195016T3 ES2195016T3 ES96935352T ES96935352T ES2195016T3 ES 2195016 T3 ES2195016 T3 ES 2195016T3 ES 96935352 T ES96935352 T ES 96935352T ES 96935352 T ES96935352 T ES 96935352T ES 2195016 T3 ES2195016 T3 ES 2195016T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- chr1r2
- chr3r4
- chr5r6
- 2chr3r4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005257 alkyl acyl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000006165 cyclic alkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 206010043554 thrombocytopenia Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/665—Phosphorus compounds having oxygen as a ring hetero atom, e.g. fosfomycin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
COMPUESTOS REPRESENTADOS POR LA FORMULA GENERAL (I) O LAS SALES DE LOS MISMOS FARMACEUTICAMENTE ACEPTABLES: (DONDE R ES UN GRUPO - NHCHR{SUB,1}R{SUB,2}, N(CHR{SUB,1}R{SUB,2}){SUB,2}, N(CHR{SUB,1}R{SUB,2})CHR{SUB,3}R{SUB,4}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,3}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,2}CHR{SUB,3}R{SUB,4} O N{SUP,+}(CHR{SUB,1}R{SUB,2})(CHR{SUB,3}R{SUB,4})CHR{SUB,5}R{SU B,6} (DONDE R{SUB,1}, R{SUB,2}, R{SUB,3}, R{SUB,4}, R{SUB,5} Y R{SUB,6}, QUE PUEDEN SER IGUALES O DIFERENTES, SON UN ATOMO DE HIDROGENO, UN GRUPO ALQUILO, UN GRUPO ALQUENILO, UN GRUPO ARILO O UN GRUPO ARALQUILO, O UN GRUPO ALQUILO, ALQUENILO, ARILO O ARALQUILO QUE ESTA SUSTITUIDO POR AL MENOS UN SUSTITUYENTE SELECCIONADO DE UN GRUPO COMPRENDIDO POR UN ATOMO DE HALOGENO, UN GRUPO HIDROXILO, UN GRUPO ALCOXI DE CADENA CORTA, UN GRUPO ALQUIACILOXI DE CADENA CORTA, UN GRUPO ALQUILACILO DE CADENA CORTA, UN GRUPO ALCOXICARBONILO DE CADENA CORTA, UN GRUPO NITRO, UN GRUPO CIANO Y UN GRUPO HETEROCICLICO, FORMANDO OPCIONALMENTEUN ALQUILO CICLICO CON CHR{SUB,1}R{SUB,2}CHR{SUB,3}R{SUB,4}, O CHR{SUB,5}R{SUB,6}, SIEMPRE QUE CUANDO R SEA N(CHR{SUB,1}R{SUB,2}CHR{SUB,3}R{SUB,4}, N{SUP,+}(CHR{SUB,1}R{SUB,2}){SUB,2}CHR{SUB,3}R{SUB,4} O N{SUP,+}(CHR{SUB,1}R{SUB,2})(CHR{SUB,3}R{SUB,4})CHR{SUB,5}R{SU B,6}, CHR{SUB,1}R{SUB,2}, CHR{SUB,3}R{SUB,4} Y CHR{SUB,5}R{SUB,6} SEAN GRUPOS DIFERENTES); LOS AGENTES TERAPEUTICOS PARA LA TROMBOCITOPENIA CONTIENEN ESTOS COMPUESTOS COMO PRINCIPIO ACTIVO EFICAZ; ASI COMO LOS INTERMEDIOS DE SU SINTESIS Y LOS PROCESOS PARA SU PRODUCCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26864495 | 1995-10-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2195016T3 true ES2195016T3 (es) | 2003-12-01 |
Family
ID=17461419
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96935352T Expired - Lifetime ES2195016T3 (es) | 1995-10-17 | 1996-10-17 | Medicamento contra la trombocitopenia. |
Country Status (9)
Country | Link |
---|---|
US (1) | US6040335A (es) |
EP (1) | EP0798304B1 (es) |
KR (1) | KR980700316A (es) |
AT (1) | ATE234315T1 (es) |
AU (1) | AU702751B2 (es) |
CA (1) | CA2207656A1 (es) |
DE (1) | DE69626624T2 (es) |
ES (1) | ES2195016T3 (es) |
WO (1) | WO1997014704A1 (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2314586B1 (en) * | 2002-01-18 | 2016-09-14 | Astellas Pharma Inc. | 2-Acylaminothiazole derivative or salt thereof |
US7851503B2 (en) | 2002-08-14 | 2010-12-14 | Nissan Chemical Industries, Ltd. | Thrombopoetin receptor activator and process for producing the same |
KR20080074166A (ko) * | 2005-11-08 | 2008-08-12 | 아스테라스 세이야쿠 가부시키가이샤 | 혈소판감소증을 치료하는 조성물 및 방법 |
AU2007284644B2 (en) * | 2006-08-08 | 2011-09-01 | Akarx, Inc. | Compositions and methods for increasing blood platelet levels in humans |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4235913A (en) * | 1977-06-07 | 1980-11-25 | Pfizer Inc. | 9-Hydroxyhexahydrodibeno[b,d]pyrans, 1-substituted-9-hydroxyhexahydrodibenzo]b,d]pyrans |
US4725602A (en) * | 1984-02-06 | 1988-02-16 | Mcneilab, Inc. | Acetylene amines and their use as vasodilators and antihypertensives |
JPH02186A (ja) * | 1987-05-07 | 1990-01-05 | Sumitomo Chem Co Ltd | 新規化合物およびそれを有効成分とする農工業用殺菌剤 |
JP2865302B2 (ja) * | 1988-02-13 | 1999-03-08 | サントリー株式会社 | 2―ピラノン誘導体及びその製造法並びにそれを含む抗菌剤 |
AU649116B2 (en) * | 1991-03-27 | 1994-05-12 | Sankyo Company Limited | New compounds, named the "Leustroducins", their preparation and their therapeutic uses |
JP3034646B2 (ja) * | 1991-06-20 | 2000-04-17 | 三共株式会社 | G−csfおよびgm−csf誘導剤 |
JPH05213758A (ja) * | 1992-02-06 | 1993-08-24 | Sankyo Co Ltd | 血小板増多剤 |
JPH05221867A (ja) * | 1992-02-17 | 1993-08-31 | Sankyo Co Ltd | Il−6誘導剤 |
EP0622372B1 (en) * | 1993-04-23 | 1998-05-13 | Sankyo Company Limited | New compound, leustroducsin H, its preparation and its therapeutic use |
JPH0841087A (ja) * | 1994-08-03 | 1996-02-13 | Sankyo Co Ltd | N−アシルロイストロダクシン類 |
-
1996
- 1996-10-17 KR KR1019970704073A patent/KR980700316A/ko not_active Application Discontinuation
- 1996-10-17 US US08/849,887 patent/US6040335A/en not_active Expired - Fee Related
- 1996-10-17 DE DE69626624T patent/DE69626624T2/de not_active Expired - Fee Related
- 1996-10-17 WO PCT/JP1996/003008 patent/WO1997014704A1/ja not_active Application Discontinuation
- 1996-10-17 EP EP96935352A patent/EP0798304B1/en not_active Expired - Lifetime
- 1996-10-17 ES ES96935352T patent/ES2195016T3/es not_active Expired - Lifetime
- 1996-10-17 CA CA002207656A patent/CA2207656A1/en not_active Abandoned
- 1996-10-17 AT AT96935352T patent/ATE234315T1/de not_active IP Right Cessation
- 1996-10-17 AU AU73329/96A patent/AU702751B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0798304A1 (en) | 1997-10-01 |
ATE234315T1 (de) | 2003-03-15 |
US6040335A (en) | 2000-03-21 |
DE69626624D1 (de) | 2003-04-17 |
WO1997014704A1 (fr) | 1997-04-24 |
EP0798304B1 (en) | 2003-03-12 |
CA2207656A1 (en) | 1997-04-24 |
AU7332996A (en) | 1997-05-07 |
AU702751B2 (en) | 1999-03-04 |
DE69626624T2 (de) | 2003-11-27 |
EP0798304A4 (en) | 1999-02-10 |
KR980700316A (ko) | 1998-03-30 |
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