ES2194993T3 - Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados. - Google Patents

Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados.

Info

Publication number
ES2194993T3
ES2194993T3 ES96918133T ES96918133T ES2194993T3 ES 2194993 T3 ES2194993 T3 ES 2194993T3 ES 96918133 T ES96918133 T ES 96918133T ES 96918133 T ES96918133 T ES 96918133T ES 2194993 T3 ES2194993 T3 ES 2194993T3
Authority
ES
Spain
Prior art keywords
blood cells
refrigerated
red blood
oxygen
erythrocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96918133T
Other languages
English (en)
Inventor
Mark W Bitensky
Tatsuro Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of ES2194993T3 publication Critical patent/ES2194993T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts

Abstract

SE DESCRIBE UN PROCEDIMIENTO BARATO DE ALMACENAJE A 4 C QUE CONSERVA LA CALIDAD DE LOS GLOBULOS ROJOS Y PROLONGA LA SUPERVIVENCIA IN VIVO DESPUES DE UNA TRANSFUSION. SE CONSIGUE LA CONSERVACION DE LOS NIVELES DE ADENOSINA TRIFOSFATO Y LA REDUCCION DE LA HEMOLISIS Y DE LA PRODUCCION DE VESICULAS DE MEMBRANA DE GLOBULOS ROJOS ALMACENADOS A 4 DE TIEMPO, MEDIANTE LA ELIMINACION DEL OXIGENO DE ELLOS EN EL MOMENTO DEL ALMACENAJE. EN ALGUNAS MUESTRAS SE AUMENTAN LOS NIVELES DE ADENOSINA TRIFOSFATO DE LOS GLOBULOS ROJOS ALMACENADOS MEDIANTE LA ADICION DE FOSFATO DE AMONIO.
ES96918133T 1995-06-05 1996-06-05 Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados. Expired - Lifetime ES2194993T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/473,675 US5624794A (en) 1995-06-05 1995-06-05 Method for extending the useful shelf-life of refrigerated red blood cells by flushing with inert gas

Publications (1)

Publication Number Publication Date
ES2194993T3 true ES2194993T3 (es) 2003-12-01

Family

ID=23880537

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96918133T Expired - Lifetime ES2194993T3 (es) 1995-06-05 1996-06-05 Metodo que utiliza la extraccion de oxigeno para prolongar la vida util de eritrocitos refrigerados.

Country Status (13)

Country Link
US (1) US5624794A (es)
EP (1) EP0830058B1 (es)
JP (1) JP4303786B2 (es)
KR (1) KR100395033B1 (es)
CN (1) CN1153512C (es)
AT (1) ATE232359T1 (es)
AU (1) AU710467B2 (es)
BR (1) BR9608404A (es)
CA (1) CA2223130C (es)
DE (1) DE69626204T2 (es)
ES (1) ES2194993T3 (es)
RU (1) RU2181542C2 (es)
WO (1) WO1996039026A1 (es)

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US5789151A (en) * 1997-05-15 1998-08-04 The Regents Of The University Of California Prolonged cold storage of red blood cells by oxygen removal and additive usage
US20030215784A1 (en) * 1998-07-21 2003-11-20 Dumont Larry Joe Method and apparatus for inactivation of biological contaminants using photosensitizers
US20070099170A1 (en) * 1998-07-21 2007-05-03 Navigant Biotechnologies, Inc. Method for treatment and storage of blood and blood products using endogenous alloxazines and acetate
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7498156B2 (en) * 1998-07-21 2009-03-03 Caridianbct Biotechnologies, Llc Use of visible light at wavelengths of 500 to 550 nm to reduce the number of pathogens in blood and blood components
US7648699B2 (en) * 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7985588B2 (en) * 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US6548241B1 (en) 2000-11-28 2003-04-15 Gambro, Inc. Storage solution containing photosensitizer for inactivation of biological contaminants
JP2005535279A (ja) * 2001-11-16 2005-11-24 ホリンガー・ディジタル・インコーポレイテッド 栄養サプリメンテーションによる冷蔵赤血球の有効貯蔵期間を延長するための方法
JP4564260B2 (ja) * 2001-11-16 2010-10-20 ヒーマネクスト・エルエルシー 血液保存のための添加溶液
US20090023130A1 (en) * 2003-02-28 2009-01-22 Caridianbct Biotechnologies, Llc Prevention of Transfusion Related Acute Lung Injury Using Riboflavin and Light
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
US9314014B2 (en) 2004-02-18 2016-04-19 University Of Maryland, Baltimore Compositions and methods for the storage of red blood cells
CN1325518C (zh) * 2005-09-09 2007-07-11 李勇 人细胞膜抗原的保存方法及磁性粒子包被人细胞膜抗原
WO2008039382A2 (en) * 2006-09-21 2008-04-03 Kyphon Sarl Diammonium phosphate and other ammonium salts and their use in preventing clotting
WO2009018309A2 (en) * 2007-08-01 2009-02-05 Caridianbct Biotechnologies, Llc Pathogen inactivation of whole blood
US8871434B2 (en) * 2008-03-21 2014-10-28 Fenwal, Inc. Red blood cell storage medium for extended storage
US8968992B2 (en) * 2008-03-21 2015-03-03 Fenwal, Inc. Red blood cell storage medium for extended storage
NZ622456A (en) * 2009-10-12 2015-09-25 New Health Sciences Inc Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
US9199016B2 (en) * 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
NZ599890A (en) 2009-10-12 2014-03-28 Univ Pittsburgh Oxygen depletion devices and methods for removing oxygen from red blood cells
EP2490751B1 (en) 2009-10-23 2016-11-09 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
WO2012027582A1 (en) 2010-08-25 2012-03-01 New Health Sciences Method for enhancing red blood cell quality and survival during storage
EP4218412A1 (en) 2010-11-05 2023-08-02 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
CA2826969C (en) 2010-11-29 2019-02-19 New York Blood Center, Inc. Method of blood pooling and storage
EP2685815A4 (en) 2011-03-16 2014-09-17 Mayo Foundation METHODS AND MATERIALS FOR EXTENDING USEFUL STORAGE OF PREPARATIONS OF HEMATIES AND PLATELET PREPARATIONS
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
CN107096081B (zh) * 2011-03-28 2019-09-06 新健康科学股份有限公司 用于在红细胞血液处理过程中使用惰性载气和歧管组件去除氧和二氧化碳的方法和系统
EP4190154A1 (en) 2011-07-05 2023-06-07 Hemanext Inc. A system for extended storage of red blood cells
ES2576977T3 (es) 2011-08-10 2016-07-12 New Health Sciences, Inc. Empobrecimiento integrado de leucocitos, oxígeno y/o CO2 y dispositivo de filtro de separación de plasma
EP2760991B1 (en) 2011-09-26 2017-12-13 Rich Technologies Holding Company, LLC Method for living tissue preservation
US9977037B2 (en) 2012-05-22 2018-05-22 New Health Sciences, Inc. Capillary network devices and methods of use
EP4032402A1 (en) * 2012-11-30 2022-07-27 Rich Technologies Holding Company, LLC Erythrocyte preservation system
ES2900298T3 (es) 2013-02-28 2022-03-16 Hemanext Inc Dispositivo de agotamiento de gas para productos sanguíneos
WO2015137499A2 (ja) * 2014-03-13 2015-09-17 ＭｉＺ株式会社 水素含有生体適用液の製造方法及びそのための外装体
CA3211996A1 (en) 2015-03-10 2016-09-15 Hemanext Inc. Oxygen reduction disposable kits, devices and methods of use thereof
AU2016253005B2 (en) 2015-04-23 2020-07-09 Hemanext Inc. Anaerobic blood storage containers
AU2016264327B2 (en) * 2015-05-18 2021-12-23 Hemanext Inc. Methods for the storage of whole blood, and compositions thereof
EP3463466B1 (en) 2016-05-27 2022-02-16 Hemanext Inc. Anaerobic blood storage and pathogen inactivation method
IL297507B2 (en) 2016-06-23 2024-01-01 Hemanext Inc Methods for treating side effects in patient populations requiring transfusions
BR112019024249A2 (pt) 2017-05-19 2020-06-02 New Health Sciences, Inc. Métodos e tratamento de trauma
CN107873696B (zh) * 2017-11-14 2020-12-11 上海市血液中心 一种熊科动物红细胞保存液及其应用
BR112021008448A2 (pt) 2018-11-16 2021-09-14 Hemanext Inc. Métodos para gerenciar eventos adversos em pacientes com inflamação
CN110447634A (zh) * 2019-06-27 2019-11-15 浙江省疾病预防控制中心 一种猴红细胞保存液及应用
CN110199987A (zh) * 2019-07-22 2019-09-06 深圳市未来细胞生命科技有限公司 一种间充质干细胞保存液及其保存方法和应用
CN114288484B (zh) * 2021-12-10 2023-01-03 中国人民解放军军事科学院军事医学研究院 低氧过滤血袋系统、血袋系统以及血液处理方法
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IE55228B1 (en) * 1982-04-27 1990-07-04 Wellcome Found Tricyclic compounds,preparation,and use
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells

Also Published As

Publication number Publication date
EP0830058A4 (en) 1999-04-14
CA2223130A1 (en) 1996-12-12
CN1153512C (zh) 2004-06-16
US5624794A (en) 1997-04-29
DE69626204T2 (de) 2003-12-11
JP4303786B2 (ja) 2009-07-29
ATE232359T1 (de) 2003-02-15
DE69626204D1 (de) 2003-03-20
KR19990022393A (ko) 1999-03-25
AU710467B2 (en) 1999-09-23
AU6047096A (en) 1996-12-24
WO1996039026A1 (en) 1996-12-12
CA2223130C (en) 2005-02-08
EP0830058B1 (en) 2003-02-12
CN1195965A (zh) 1998-10-14
JPH11506777A (ja) 1999-06-15
BR9608404A (pt) 1999-11-30
EP0830058A1 (en) 1998-03-25
KR100395033B1 (ko) 2003-12-31
RU2181542C2 (ru) 2002-04-27

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