ES2194939T3 - Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo. - Google Patents
Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo.Info
- Publication number
- ES2194939T3 ES2194939T3 ES96106691T ES96106691T ES2194939T3 ES 2194939 T3 ES2194939 T3 ES 2194939T3 ES 96106691 T ES96106691 T ES 96106691T ES 96106691 T ES96106691 T ES 96106691T ES 2194939 T3 ES2194939 T3 ES 2194939T3
- Authority
- ES
- Spain
- Prior art keywords
- necrosis factor
- simultaneous
- blood
- bacterial
- lipopolisacarids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
- A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
- A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Anesthesiology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Cardiology (AREA)
- External Artificial Organs (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
PARA LA ELIMINACION EXTRACORPORAL DEL FACTOR AL DE LA NECROSIS TUMORAL (TNF {AL}) O/Y DE LIPOPOLISACARIDOS BACTERIANOS (LPS, ENDOTOXINA) DE LA SANGRE Y/O DEL PLASMA SANGUINEO EN UN SISTEMA DE PERFUSION EXTRACORPORAL, SE LLEVA LA SANGRE O EL PLASMA POR UN MATERIAL INTERCAMBIADOR DE CATIONES Y POR UNO DE ANIONES. POR TANTO, UN DISPOSITIVO DE ACUERDO CON LA INVENCION PARA EL TRATAMIENTO EXTRACORPORAL DE LA SANGRE O PLASMA DE PACIENTES, CONTIENE UN MATERIAL INTERCAMBIADOR DE CATIONES Y OTRO DE ANIONES, ESTANDO ESTOS MATERIALES EN AL MENOS UNA PARTE DEL SISTEMA DE PERFUSION EXTRACORPORAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19515554A DE19515554C2 (de) | 1995-04-27 | 1995-04-27 | Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2194939T3 true ES2194939T3 (es) | 2003-12-01 |
Family
ID=7760536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96106691T Expired - Lifetime ES2194939T3 (es) | 1995-04-27 | 1996-04-26 | Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5679775A (es) |
EP (1) | EP0739630B1 (es) |
JP (1) | JP2804920B2 (es) |
AT (1) | ATE234104T1 (es) |
DE (3) | DE19549420A1 (es) |
ES (1) | ES2194939T3 (es) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127528A (en) * | 1995-02-16 | 2000-10-03 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Process for adsorbing and removing tumor necrosis factor-α |
US6620382B1 (en) * | 1998-05-22 | 2003-09-16 | Biopheresis Technologies, Llc. | Method and compositions for treatment of cancers |
DE19831873A1 (de) * | 1998-07-16 | 2000-03-30 | Jens Altrichter | Verfahren und Einrichtung zur therapeutischen Immunmodulation |
US20030130194A1 (en) * | 1998-07-16 | 2003-07-10 | Jens Altrichter | Method and device for increasing and/or decreasing the concentration of immunomodulatory-active substances in substance mixtures |
DE19845286A1 (de) * | 1998-10-01 | 2000-04-27 | Udo Dunzendorfer | Beschichtete Trägermaterialien für Blut-, Plasma- oder Gewebewäsche und mit diesen Trägermaterialien ausgerüstete Säulen |
DE19913707A1 (de) * | 1999-03-26 | 2000-10-05 | Privates Inst Bioserv Gmbh | Immunadsorber zur Sepsistherapie |
US6290946B1 (en) * | 1999-05-13 | 2001-09-18 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders and antibacterial agents |
US6270755B1 (en) | 1999-05-13 | 2001-08-07 | Geltex Pharmaceuticals, Inc. | Anionic polymers as toxin binders |
CA2314494A1 (en) | 2000-05-02 | 2001-11-02 | Geltex Pharmaceuticals, Inc. | Anionic polymers as species specific antibacterial agents |
US6884228B2 (en) | 2001-03-06 | 2005-04-26 | Baxter International Inc. | Automated system adaptable for use with different fluid circuits |
US6582386B2 (en) | 2001-03-06 | 2003-06-24 | Baxter International Inc. | Multi-purpose, automated blood and fluid processing systems and methods |
US6706008B2 (en) | 2001-03-06 | 2004-03-16 | Baxter International Inc. | Automated system and method for withdrawing compounds from blood |
DE10118446A1 (de) * | 2001-04-12 | 2002-10-17 | Thomas Hartung | Prüfverfahren zur Untersuchung fließfähiger Medien auf Gehalte an mikrobiellen Toxinen |
US6803183B2 (en) | 2002-07-18 | 2004-10-12 | Clarigen, Inc. | Method for removing pyrogens from plasma and blood for treatment of septic shock |
KR20050030208A (ko) * | 2002-07-22 | 2005-03-29 | 젠자임 코포레이션 | 폴리(칼륨 및 나트륨 스티렌 설포네이트), 이의 제조방법및 용도 |
FR2848223B1 (fr) * | 2002-12-09 | 2005-02-25 | Centre Nat Rech Scient | Nouveau procede d'isolement des endotoxines. |
DE10258944A1 (de) * | 2002-12-17 | 2004-07-01 | B. Braun Medizintechnologie Gmbh | Vorrichtung zur Entfernung von bakteriellen Lipopolysacchariden oder/und Lipoteichonsäuren aus proteinhaltigen Flüssigkeiten sowie deren Verwendung zur Behandlung von Sepsis |
WO2004056318A2 (en) | 2002-12-19 | 2004-07-08 | New York University | Method for treating amyloid disease |
AT413336B (de) * | 2003-09-12 | 2006-02-15 | Mattner Frank Dr | Apherese-vorrichtung |
GB0408521D0 (en) * | 2004-04-16 | 2004-05-19 | Carbon Technologies Nv | Treatment of sepsis |
ATE356643T1 (de) * | 2004-06-03 | 2007-04-15 | Braun Medizintechnologie Gmbh | Vorrichtung zur entfernung von bakteriellen lipopolysacchariden oder/und lipoteichonsäuren aus proteinhaltigen flüssigkeiten sowie verwendung zur herstellung eines mittels zur entfernung dieser stoffe |
CA2637686A1 (en) | 2006-02-02 | 2007-08-16 | Innovative Bio Therapies | An extracorporeal cell-based therapeutic device and delivery system |
US9101716B2 (en) | 2008-02-01 | 2015-08-11 | Baxter International Inc. | Multi-pass dialysis |
US9029144B2 (en) | 2008-06-18 | 2015-05-12 | Innovative Bio Therapies, Inc. | Methods for enhanced propagation of cells |
EP2679302A1 (de) | 2012-06-28 | 2014-01-01 | Zentrum für biomedizinische Technologie der Donau- Universität Krems | Selektives Sorptionsmittel für die extrakorporale Blutreinigung |
JP2017513636A (ja) * | 2014-04-24 | 2017-06-01 | エクスセラ メディカル コーポレイション | 高流量を用いて血液から細菌を除去するための方法 |
NL2013880B1 (en) | 2014-11-26 | 2016-10-11 | Rousselot B V | Gelatin purification. |
JP6884774B2 (ja) | 2015-10-22 | 2021-06-09 | サイトソーベンツ・コーポレーション | 生体液よりタンパク質ベースの毒素とカリウムを除去するための多機能性の血液適合性多孔性ポリマービーズ吸着剤 |
US11911551B2 (en) | 2016-03-02 | 2024-02-27 | Exthera Medical Corporation | Method for treating drug intoxication |
US11357608B2 (en) * | 2019-02-16 | 2022-06-14 | Eyal Israely | Leech therapy device |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1601333A (es) * | 1968-12-03 | 1970-08-17 | ||
US3959128A (en) * | 1974-12-27 | 1976-05-25 | Preventive Systems, Inc | Process for removing endotoxin from biological fluids |
US4059512A (en) * | 1974-12-27 | 1977-11-22 | Preventive Systems, Inc. | Process for removing endotoxin from biological fluids |
JPS6040863B2 (ja) * | 1976-07-02 | 1985-09-12 | 富田製薬株式会社 | 医療用吸着剤 |
NL7703937A (nl) * | 1977-04-12 | 1978-10-16 | Organon Teknika Bv | Inrichting voorzien van een sorbent voor het zuiveren van bloed; een voor orale toepassing geschikt sorbent en een werkwijze voor vervaar- diging van het sorbent. |
JPS56141833A (en) * | 1980-04-03 | 1981-11-05 | Honda Motor Co Ltd | Urea selective adsorbent |
DE3110128A1 (de) * | 1981-03-16 | 1982-09-23 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V., 8000 München | Verfahren und vorrichtung zur entgiftung und regeneration von blut, blutbestandteilen und bei der blutreinigung anfallenden loesungen sowie kit fuer die durchfuehrung des verfahrens |
EP0174478B1 (de) * | 1981-09-10 | 1991-12-11 | B. Braun Holding AG | Verfahren zur selektiven extrakorporalen Präzipitation von Low Density Lipoproteinen aus Vollserum oder Plasma |
DE3135814A1 (de) * | 1981-09-10 | 1983-03-24 | B. Braun Melsungen Ag, 3508 Melsungen | Verfahren und vorrichtung zur selektiven extrakorporalen praezipitation von low density lipoproteinen aus vollserum oder plasma |
CA1221307A (en) * | 1982-12-02 | 1987-05-05 | Nobutaka Tani | Adsorbent and process for preparing the same |
US5059654A (en) * | 1983-02-14 | 1991-10-22 | Cuno Inc. | Affinity matrices of modified polysaccharide supports |
DE3422494A1 (de) * | 1984-06-16 | 1985-12-19 | B. Braun Melsungen Ag, 3508 Melsungen | Verfahren und vorrichtung zur spezifischen adsorption von heparin |
US5100677A (en) * | 1985-12-18 | 1992-03-31 | Veech Richard L | Fluid therapy with various organic anions |
JPS61124392A (ja) * | 1984-11-22 | 1986-06-12 | Asahi Chem Ind Co Ltd | 遺伝子組換体の産生する生理活性物質の精製法 |
JPH0622624B2 (ja) * | 1985-07-31 | 1994-03-30 | 旭化成工業株式会社 | 低比重リポ蛋白質吸着材の再生方法 |
US4777242A (en) * | 1986-10-10 | 1988-10-11 | Phillips Petroleum Company | Purification of recombinant tumor necrosis factor |
US5108596A (en) * | 1988-04-05 | 1992-04-28 | Kanebo Ltd. | Borous ion-exchanged fine cellulose particles, method for production thereof, and affinity carrier |
US5055447A (en) * | 1988-07-28 | 1991-10-08 | Genentech, Inc. | Method and compositions for the treatment and prevention of septic shock |
US5178864A (en) * | 1990-08-14 | 1993-01-12 | Mit | Lipoprotein removal by soluble enzymes |
KR930007780B1 (ko) * | 1990-11-19 | 1993-08-19 | 삼성전자 주식회사 | 로보트의 위치 제어방법 |
DE4209988A1 (de) * | 1991-04-23 | 1993-03-04 | Falkenhagen Dieter Dr Sc Med | Endotoxinadsorber und verfahren zu seiner herstellung |
US5252216A (en) * | 1992-03-24 | 1993-10-12 | Smithkline Beecham Corporation | Protein purification |
DE4331358A1 (de) * | 1992-10-12 | 1994-04-14 | Braun Melsungen Ag | Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten |
DE4435612A1 (de) * | 1994-10-05 | 1996-04-11 | Braun Melsungen Ag | Verfahren zur simultanen Entfernung von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus einer wäßrigen Flüssigkeit |
-
1995
- 1995-04-27 DE DE19549420A patent/DE19549420A1/de active Pending
- 1995-04-27 DE DE19515554A patent/DE19515554C2/de not_active Expired - Fee Related
-
1996
- 1996-04-19 US US08/634,919 patent/US5679775A/en not_active Expired - Lifetime
- 1996-04-25 JP JP8105876A patent/JP2804920B2/ja not_active Expired - Fee Related
- 1996-04-26 ES ES96106691T patent/ES2194939T3/es not_active Expired - Lifetime
- 1996-04-26 AT AT96106691T patent/ATE234104T1/de active
- 1996-04-26 DE DE59610208T patent/DE59610208D1/de not_active Expired - Lifetime
- 1996-04-26 EP EP96106691A patent/EP0739630B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0739630B1 (de) | 2003-03-12 |
EP0739630A2 (de) | 1996-10-30 |
US5679775A (en) | 1997-10-21 |
ATE234104T1 (de) | 2003-03-15 |
DE19549420A1 (de) | 1997-09-18 |
EP0739630A3 (de) | 1999-09-29 |
DE19515554A1 (de) | 1996-10-31 |
DE59610208D1 (de) | 2003-04-17 |
JPH08299436A (ja) | 1996-11-19 |
DE19515554C2 (de) | 1999-06-17 |
JP2804920B2 (ja) | 1998-09-30 |
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