ES2194939T3 - Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo. - Google Patents

Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo.

Info

Publication number
ES2194939T3
ES2194939T3 ES96106691T ES96106691T ES2194939T3 ES 2194939 T3 ES2194939 T3 ES 2194939T3 ES 96106691 T ES96106691 T ES 96106691T ES 96106691 T ES96106691 T ES 96106691T ES 2194939 T3 ES2194939 T3 ES 2194939T3
Authority
ES
Spain
Prior art keywords
necrosis factor
simultaneous
blood
bacterial
lipopolisacarids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96106691T
Other languages
English (en)
Inventor
Karl-Siegfried Prof Dr Boos
Dietrich Prof Dr Med Seidel
Annette Trautwein
Gerold Morsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
B Braun Melsungen AG
Original Assignee
B Braun Melsungen AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by B Braun Melsungen AG filed Critical B Braun Melsungen AG
Application granted granted Critical
Publication of ES2194939T3 publication Critical patent/ES2194939T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PARA LA ELIMINACION EXTRACORPORAL DEL FACTOR AL DE LA NECROSIS TUMORAL (TNF {AL}) O/Y DE LIPOPOLISACARIDOS BACTERIANOS (LPS, ENDOTOXINA) DE LA SANGRE Y/O DEL PLASMA SANGUINEO EN UN SISTEMA DE PERFUSION EXTRACORPORAL, SE LLEVA LA SANGRE O EL PLASMA POR UN MATERIAL INTERCAMBIADOR DE CATIONES Y POR UNO DE ANIONES. POR TANTO, UN DISPOSITIVO DE ACUERDO CON LA INVENCION PARA EL TRATAMIENTO EXTRACORPORAL DE LA SANGRE O PLASMA DE PACIENTES, CONTIENE UN MATERIAL INTERCAMBIADOR DE CATIONES Y OTRO DE ANIONES, ESTANDO ESTOS MATERIALES EN AL MENOS UNA PARTE DEL SISTEMA DE PERFUSION EXTRACORPORAL.
ES96106691T 1995-04-27 1996-04-26 Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo. Expired - Lifetime ES2194939T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19515554A DE19515554C2 (de) 1995-04-27 1995-04-27 Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma

Publications (1)

Publication Number Publication Date
ES2194939T3 true ES2194939T3 (es) 2003-12-01

Family

ID=7760536

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96106691T Expired - Lifetime ES2194939T3 (es) 1995-04-27 1996-04-26 Procedimiento para la eliminacion extracorporal simultanea del factor de necrosis de tumores alfa y de los lipopolisacaridos bacterianos a partir de sangre entera y/o plasma sanguineo.

Country Status (6)

Country Link
US (1) US5679775A (es)
EP (1) EP0739630B1 (es)
JP (1) JP2804920B2 (es)
AT (1) ATE234104T1 (es)
DE (3) DE19549420A1 (es)
ES (1) ES2194939T3 (es)

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US6620382B1 (en) * 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers
DE19831873A1 (de) * 1998-07-16 2000-03-30 Jens Altrichter Verfahren und Einrichtung zur therapeutischen Immunmodulation
US20030130194A1 (en) * 1998-07-16 2003-07-10 Jens Altrichter Method and device for increasing and/or decreasing the concentration of immunomodulatory-active substances in substance mixtures
DE19845286A1 (de) * 1998-10-01 2000-04-27 Udo Dunzendorfer Beschichtete Trägermaterialien für Blut-, Plasma- oder Gewebewäsche und mit diesen Trägermaterialien ausgerüstete Säulen
DE19913707A1 (de) * 1999-03-26 2000-10-05 Privates Inst Bioserv Gmbh Immunadsorber zur Sepsistherapie
US6290946B1 (en) * 1999-05-13 2001-09-18 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders and antibacterial agents
US6270755B1 (en) 1999-05-13 2001-08-07 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders
CA2314494A1 (en) 2000-05-02 2001-11-02 Geltex Pharmaceuticals, Inc. Anionic polymers as species specific antibacterial agents
US6884228B2 (en) 2001-03-06 2005-04-26 Baxter International Inc. Automated system adaptable for use with different fluid circuits
US6582386B2 (en) 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
US6706008B2 (en) 2001-03-06 2004-03-16 Baxter International Inc. Automated system and method for withdrawing compounds from blood
DE10118446A1 (de) * 2001-04-12 2002-10-17 Thomas Hartung Prüfverfahren zur Untersuchung fließfähiger Medien auf Gehalte an mikrobiellen Toxinen
US6803183B2 (en) 2002-07-18 2004-10-12 Clarigen, Inc. Method for removing pyrogens from plasma and blood for treatment of septic shock
KR20050030208A (ko) * 2002-07-22 2005-03-29 젠자임 코포레이션 폴리(칼륨 및 나트륨 스티렌 설포네이트), 이의 제조방법및 용도
FR2848223B1 (fr) * 2002-12-09 2005-02-25 Centre Nat Rech Scient Nouveau procede d'isolement des endotoxines.
DE10258944A1 (de) * 2002-12-17 2004-07-01 B. Braun Medizintechnologie Gmbh Vorrichtung zur Entfernung von bakteriellen Lipopolysacchariden oder/und Lipoteichonsäuren aus proteinhaltigen Flüssigkeiten sowie deren Verwendung zur Behandlung von Sepsis
WO2004056318A2 (en) 2002-12-19 2004-07-08 New York University Method for treating amyloid disease
AT413336B (de) * 2003-09-12 2006-02-15 Mattner Frank Dr Apherese-vorrichtung
GB0408521D0 (en) * 2004-04-16 2004-05-19 Carbon Technologies Nv Treatment of sepsis
ATE356643T1 (de) * 2004-06-03 2007-04-15 Braun Medizintechnologie Gmbh Vorrichtung zur entfernung von bakteriellen lipopolysacchariden oder/und lipoteichonsäuren aus proteinhaltigen flüssigkeiten sowie verwendung zur herstellung eines mittels zur entfernung dieser stoffe
CA2637686A1 (en) 2006-02-02 2007-08-16 Innovative Bio Therapies An extracorporeal cell-based therapeutic device and delivery system
US9101716B2 (en) 2008-02-01 2015-08-11 Baxter International Inc. Multi-pass dialysis
US9029144B2 (en) 2008-06-18 2015-05-12 Innovative Bio Therapies, Inc. Methods for enhanced propagation of cells
EP2679302A1 (de) 2012-06-28 2014-01-01 Zentrum für biomedizinische Technologie der Donau- Universität Krems Selektives Sorptionsmittel für die extrakorporale Blutreinigung
JP2017513636A (ja) * 2014-04-24 2017-06-01 エクスセラ メディカル コーポレイション 高流量を用いて血液から細菌を除去するための方法
NL2013880B1 (en) 2014-11-26 2016-10-11 Rousselot B V Gelatin purification.
JP6884774B2 (ja) 2015-10-22 2021-06-09 サイトソーベンツ・コーポレーション 生体液よりタンパク質ベースの毒素とカリウムを除去するための多機能性の血液適合性多孔性ポリマービーズ吸着剤
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
US11357608B2 (en) * 2019-02-16 2022-06-14 Eyal Israely Leech therapy device

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Also Published As

Publication number Publication date
EP0739630B1 (de) 2003-03-12
EP0739630A2 (de) 1996-10-30
US5679775A (en) 1997-10-21
ATE234104T1 (de) 2003-03-15
DE19549420A1 (de) 1997-09-18
EP0739630A3 (de) 1999-09-29
DE19515554A1 (de) 1996-10-31
DE59610208D1 (de) 2003-04-17
JPH08299436A (ja) 1996-11-19
DE19515554C2 (de) 1999-06-17
JP2804920B2 (ja) 1998-09-30

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