ES2192187T3 - Procedimiento para la obtencion de sales de fosfonio. - Google Patents
Procedimiento para la obtencion de sales de fosfonio.Info
- Publication number
- ES2192187T3 ES2192187T3 ES01104628T ES01104628T ES2192187T3 ES 2192187 T3 ES2192187 T3 ES 2192187T3 ES 01104628 T ES01104628 T ES 01104628T ES 01104628 T ES01104628 T ES 01104628T ES 2192187 T3 ES2192187 T3 ES 2192187T3
- Authority
- ES
- Spain
- Prior art keywords
- trimethyldodeca
- tetraen
- salts
- iii
- phosphone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003839 salts Chemical class 0.000 title abstract 5
- UIMSQVVHHIUQOZ-UHFFFAOYSA-N 3,7,11-trimethyldodeca-1,4,6,10-tetraen-3-ol Chemical compound CC(C)=CCCC(C)=CC=CC(C)(O)C=C UIMSQVVHHIUQOZ-UHFFFAOYSA-N 0.000 abstract 4
- TYOZJMJMPGXQJE-UHFFFAOYSA-N 3,7,11-trimethyldodeca-1,4,6,10-tetraen-3-ylphosphane Chemical class CC(=CCCC(=CC=CC(C)(C=C)P)C)C TYOZJMJMPGXQJE-UHFFFAOYSA-N 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/54—Quaternary phosphonium compounds
- C07F9/5428—Acyclic unsaturated phosphonium compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento para la obtención de sales de fosfonio. La presente invención se refiere a un procedimiento para la obtención de sales de 3, 7, 11-trimetildodeca2, 4, 6, 10-tetraen-1-il-fosfonio. Por regla general se preparan las sales de fosfonio con 15 átomos de carbono para la síntesis de carotinoides a partir de vinilcarbinoles mediante reacción con trifenilfosfano y un ácido fuerte tal como HCl o H2SO4 en disolventes próticos. En contra de lo que ocurre con el vinil-13-ionol, que es un educto empleado para la síntesis de la vitamina A y la 13-carotina, el vinil-pseudoionol únicamente puede hacerse reaccionar a modo educto, para la obtención de licopina bajo estas condiciones normalizadas con malos rendimientos y con bajas selectividades E/Z para dar las correspondientes sales de fosfonio con 15 átomos de carbono.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10009459A DE10009459C1 (de) | 2000-03-02 | 2000-03-02 | Verfahren zur Herstellung von Phosphoniumsalzen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2192187T3 true ES2192187T3 (es) | 2003-10-01 |
Family
ID=7632782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES01104628T Expired - Lifetime ES2192187T3 (es) | 2000-03-02 | 2001-02-23 | Procedimiento para la obtencion de sales de fosfonio. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6423873B1 (es) |
| EP (1) | EP1130024B1 (es) |
| JP (1) | JP2001270889A (es) |
| CN (1) | CN1173983C (es) |
| AT (1) | ATE232535T1 (es) |
| DE (2) | DE10009459C1 (es) |
| DK (1) | DK1130024T3 (es) |
| ES (1) | ES2192187T3 (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10129403A1 (de) * | 2001-06-19 | 2003-01-02 | Basf Ag | Verfahren zur Reinigung von Phosphoniumsalzen |
| CN100336819C (zh) * | 2003-10-15 | 2007-09-12 | 北京合创同盛科技有限公司 | 一种三有机膦与卤代烷烃合成鏻盐的方法 |
| WO2006118257A1 (ja) * | 2005-04-28 | 2006-11-09 | Kyowa Hakko Kogyo Co., Ltd. | インダゾール-3-イルメチルホスホニウム塩の製造法 |
| CN101037449B (zh) * | 2007-04-09 | 2010-04-07 | 广州巨元生化有限公司 | 一种季磷盐及应用于类胡萝卜素的合成 |
| EP2130833A1 (en) * | 2008-06-05 | 2009-12-09 | DSM IP Assets B.V. | Process for the preparation of zeacarotenes |
| JP5803031B2 (ja) * | 2010-10-01 | 2015-11-04 | ディーエスエム アイピー アセッツ ビー．ブイ． | ペレチノインの向上した合成 |
| CN103172673B (zh) * | 2011-12-26 | 2016-04-20 | 南京工业大学 | 3，7，11-三甲基十二碳-2，4，6，10-四烯-1-基膦盐的制备方法 |
| CN102924246B (zh) * | 2012-11-08 | 2014-06-04 | 绍兴文理学院 | 一种2,6,10-三甲基- 2,5,9-十一烷三烯-1-醛的制备方法 |
| DK2957565T3 (en) | 2014-06-18 | 2018-05-22 | Allied Biotech Corp | Methods for Preparing Lycopene from C-15-Wittig Salts and Methods for Purifying C15-Wittig Salts with High All-E Content and High 6Z Content |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1101431A (en) | 1977-06-18 | 1981-05-19 | Bernhard Schulz | Preparation of aqueous solutions or fine aqueous dispersions of polyenyltriarylphosphonium salts |
| DE2729974C3 (de) * | 1977-07-02 | 1981-09-24 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von wäßrigen Lösungen bzw. feinteiligen wäßrigen Dispersionen von Polyenyltriarylphosphoniumsalzen |
| US5166445A (en) | 1989-02-10 | 1992-11-24 | Hoffman-La Roche Inc. | Method for the manufacture of carotinoids and the novel intermediates |
| US5208381A (en) | 1989-02-10 | 1993-05-04 | Hoffmann-La Roche Inc. | Method for the manufacture of carotinoids and novel intermediates |
| DE19734446A1 (de) * | 1997-08-08 | 1999-02-11 | Basf Ag | Verfahren zur Herstellung von Phosphoniumsalzen |
-
2000
- 2000-03-02 DE DE10009459A patent/DE10009459C1/de not_active Expired - Lifetime
-
2001
- 2001-02-23 ES ES01104628T patent/ES2192187T3/es not_active Expired - Lifetime
- 2001-02-23 AT AT01104628T patent/ATE232535T1/de not_active IP Right Cessation
- 2001-02-23 DK DK01104628T patent/DK1130024T3/da active
- 2001-02-23 EP EP01104628A patent/EP1130024B1/de not_active Expired - Lifetime
- 2001-02-23 DE DE50100102T patent/DE50100102D1/de not_active Expired - Fee Related
- 2001-02-26 US US09/791,574 patent/US6423873B1/en not_active Expired - Fee Related
- 2001-03-02 JP JP2001059147A patent/JP2001270889A/ja not_active Withdrawn
- 2001-03-02 CN CNB011162538A patent/CN1173983C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1319600A (zh) | 2001-10-31 |
| DE50100102D1 (de) | 2003-03-20 |
| US6423873B1 (en) | 2002-07-23 |
| EP1130024A1 (de) | 2001-09-05 |
| JP2001270889A (ja) | 2001-10-02 |
| EP1130024B1 (de) | 2003-02-12 |
| DK1130024T3 (da) | 2003-04-22 |
| ATE232535T1 (de) | 2003-02-15 |
| DE10009459C1 (de) | 2001-06-07 |
| CN1173983C (zh) | 2004-11-03 |
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