ES2189997T3 - Empleo de polvos polimeros redispersables o granulados polimeros como agente aglutinante para la obtencion de formas de administracion farmaceuticas solidas. - Google Patents

Empleo de polvos polimeros redispersables o granulados polimeros como agente aglutinante para la obtencion de formas de administracion farmaceuticas solidas.

Info

Publication number
ES2189997T3
ES2189997T3 ES98103626T ES98103626T ES2189997T3 ES 2189997 T3 ES2189997 T3 ES 2189997T3 ES 98103626 T ES98103626 T ES 98103626T ES 98103626 T ES98103626 T ES 98103626T ES 2189997 T3 ES2189997 T3 ES 2189997T3
Authority
ES
Spain
Prior art keywords
polymer
employment
obtaining
binding agent
solid pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98103626T
Other languages
English (en)
Inventor
Karl Dr Kolter
Kristin Dr Tiefensee
Katrin Dr Zeitz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2189997T3 publication Critical patent/ES2189997T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

USO DE POLVOS DE POLIMEROS O GRANULADOS DE POLIMEROS REDISPERSABLES CON A) ENTRE 10 Y 95 % EN PESO DE ACETATO DE POLIVINILO, B) ENTRE 5 Y 90 % EN PESO DE UN POLIMERO QUE CONTIENE N VINILPIRROLIDONA, C) ENTRE 0 Y 20 % EN PESO, DE OTRA SUSTANCIA SOLUBLE EN AGUA O HINCHABLE EN AGUA Y D) ENTRE 0 Y 20 % EN PESO DE UN AGENTE PRODUCTOR DE POLVO INSOLUBLE EN AGUA, ASI COMO OPCIONALMENTE E) OTROS ADITIVOS, COMO AGLUTINANTES DE FORMAS DE ADMINISTRACION FARMACEUTICA SOLIDAS, DONDE LA CANTIDAD DE AGLUTINANTE EN LA FORMA DE ADMINISTRACION ES ENTRE 0,5 Y 20 % EN PESO.
ES98103626T 1997-03-10 1998-03-02 Empleo de polvos polimeros redispersables o granulados polimeros como agente aglutinante para la obtencion de formas de administracion farmaceuticas solidas. Expired - Lifetime ES2189997T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19709663A DE19709663A1 (de) 1997-03-10 1997-03-10 Verwendung von redispergierbaren Polymerpulvern oder Polymergranulaten als Bindemittel zur Herstellung von festen pharmazeutischen Darreichungsformen

Publications (1)

Publication Number Publication Date
ES2189997T3 true ES2189997T3 (es) 2003-07-16

Family

ID=7822750

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98103626T Expired - Lifetime ES2189997T3 (es) 1997-03-10 1998-03-02 Empleo de polvos polimeros redispersables o granulados polimeros como agente aglutinante para la obtencion de formas de administracion farmaceuticas solidas.

Country Status (8)

Country Link
US (1) US6066334A (es)
EP (1) EP0868910B1 (es)
JP (1) JPH10298111A (es)
AT (1) ATE230259T1 (es)
DE (2) DE19709663A1 (es)
DK (1) DK0868910T3 (es)
ES (1) ES2189997T3 (es)
SI (1) SI0868910T1 (es)

Families Citing this family (32)

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Publication number Priority date Publication date Assignee Title
DE19913606A1 (de) * 1999-03-25 2000-09-28 Basf Ag Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen
JP5767429B2 (ja) * 1999-11-12 2015-08-19 アッヴィ・インコーポレイテッド 固体分散剤中の結晶化阻害剤
US7364752B1 (en) 1999-11-12 2008-04-29 Abbott Laboratories Solid dispersion pharamaceutical formulations
DE10014588A1 (de) * 2000-03-27 2001-10-04 Basf Ag Wirkstoffhaltige Schwimmformen enthaltend Polyvinylacetat und Polyvinylpyrrolidon, deren Verwendung und Herstellung
DE10015479A1 (de) * 2000-03-29 2001-10-11 Basf Ag Feste orale Darreichungsformen mit retardierter Wirkstofffreisetzung und hoher mechanischer Stabilität
DE10026698A1 (de) * 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
DE10029201A1 (de) * 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
AU2002213957A1 (en) * 2000-09-29 2002-04-08 Basf Aktiengesellschaft Aqueous polymer dispersion
WO2002067905A1 (en) * 2001-02-27 2002-09-06 Kos Pharmaceuticals, Inc. A sustained release pharmaceutical formulation
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) * 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
JP4575654B2 (ja) * 2003-09-05 2010-11-04 エスエス製薬株式会社 溶解性と流動性を改善した医薬組成物
US8168219B2 (en) * 2005-11-30 2012-05-01 Isp Investments Inc. Synergistic binder composition, method for making same, and tablets of an active and said binder having advantageous hardness and friability
JP5209492B2 (ja) * 2005-12-21 2013-06-12 ビーエーエスエフ ソシエタス・ヨーロピア 速崩性錠剤製造のための医薬製剤
FR2898056B1 (fr) * 2006-03-01 2012-01-20 Ethypharm Sa Comprimes resistant a l'ecrasement destines a eviter le detournement illicite
CN102488652B (zh) 2006-03-16 2014-06-18 特瑞斯制药股份有限公司 含有药物-离子交换树脂复合物的经修饰释放的制剂
WO2008046799A2 (en) * 2006-10-20 2008-04-24 Basf Aktiengesellschaft Preparation of granules of hydrophilic vitamins
US10406105B2 (en) * 2007-06-06 2019-09-10 Basf Se Pharmaceutical formulation for the production of rapidly disintegrating tablets
EP2164461B1 (de) * 2007-06-06 2013-01-23 Basf Se Kau- und lutsch-tabletten
EP2164460B1 (de) * 2007-06-06 2017-08-09 Basf Se Pharmazeutische formulierung für die herstellung von schnell zerfallenden tabletten
JP5750266B2 (ja) * 2008-02-28 2015-07-15 アッヴィ・インコーポレイテッド 錠剤およびその調製
WO2010034688A2 (de) * 2008-09-25 2010-04-01 Basf Se Verwendung von copolymeren auf basis von polyethern und vinylmonomeren als bindemittel für feste wirkstoffhaltige dosierungsformen
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
US8287903B2 (en) 2011-02-15 2012-10-16 Tris Pharma Inc Orally effective methylphenidate extended release powder and aqueous suspension product
DE102011121589A1 (de) * 2011-12-20 2013-06-20 Johns Manville Europe Gmbh Binderverfestigtes, textiles Flächengebilde, Verfahren zu dessen Herstellung und dessen Verwendung
AU2013302657B2 (en) 2012-08-15 2018-08-09 Tris Pharma, Inc. Methylphenidate extended release chewable tablet
CN104644557B (zh) * 2013-11-22 2017-10-31 上海宣泰医药科技有限公司 卟啉铁固体分散体及其制备方法
US11590228B1 (en) 2015-09-08 2023-02-28 Tris Pharma, Inc Extended release amphetamine compositions
CA3042770A1 (en) * 2016-11-07 2018-05-11 Merck Patent Gmbh Anti-alcohol-induced dose dumping tablet based on polyvinyl alcohol
US11590081B1 (en) 2017-09-24 2023-02-28 Tris Pharma, Inc Extended release amphetamine tablets
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition
WO2024163966A1 (en) 2023-02-03 2024-08-08 Tris Pharma, Inc. Low sodium oxybate once nightly composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837032A (en) * 1986-02-04 1989-06-06 Farval Ag Theophylline sustained release tablet
DE3810343A1 (de) * 1988-03-26 1989-10-05 Basf Ag Verfahren zur herstellung von festen pharmazeutischen retardformen
US5252704A (en) * 1992-06-05 1993-10-12 Air Products And Chemicals, Inc. Redispersible polymer powders using polyvinyl pyrrolidone as a dispersing aid
DE4220782A1 (de) * 1992-06-25 1994-01-05 Basf Ag Verfahren zur Herstellung von festen pharmazeutischen Retardformen
US5705553A (en) * 1993-05-29 1998-01-06 Hoechst Aktiengesellschaft Copolymers containing carboxyl groups in aqueous dispersion form or redispersible powder form and their water-soluble salts, processes for their preparation and their use as thickeners in aqueous formulations
DE4341156C2 (de) * 1993-12-02 1997-11-13 Wacker Chemie Gmbh Verwendung von in Wasser redispergierbaren Kunststoffdispersionspulvern als Arzneimittelträger
FR2727976A1 (fr) * 1994-12-09 1996-06-14 Rhone Poulenc Chimie Poudres redispersables dans l'eau de polymeres filmogenes prepares a partir de monomeres a insaturation ethylenique
DE19711712A1 (de) * 1997-03-20 1998-09-24 Wacker Chemie Gmbh Verfahren zur Herstellung von blockstabilen, in Wasser redispergierbaren Polymerpulvern

Also Published As

Publication number Publication date
JPH10298111A (ja) 1998-11-10
DE19709663A1 (de) 1998-09-17
SI0868910T1 (en) 2003-04-30
US6066334A (en) 2000-05-23
EP0868910B1 (de) 2003-01-02
DK0868910T3 (da) 2003-02-24
DE59806776D1 (de) 2003-02-06
EP0868910A2 (de) 1998-10-07
EP0868910A3 (de) 1999-09-15
ATE230259T1 (de) 2003-01-15

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