ES2189905T3 - Procedimiento para la preparacion de pirazin-2-aminas. - Google Patents

Procedimiento para la preparacion de pirazin-2-aminas.

Info

Publication number
ES2189905T3
ES2189905T3 ES97111847T ES97111847T ES2189905T3 ES 2189905 T3 ES2189905 T3 ES 2189905T3 ES 97111847 T ES97111847 T ES 97111847T ES 97111847 T ES97111847 T ES 97111847T ES 2189905 T3 ES2189905 T3 ES 2189905T3
Authority
ES
Spain
Prior art keywords
formula
oxypyrazine
vii
alkoxy
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97111847T
Other languages
English (en)
Inventor
Walter Dr Brieden
Rudolf Dr Fuchs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lonza AG
Original Assignee
Lonza AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza AG filed Critical Lonza AG
Application granted granted Critical
Publication of ES2189905T3 publication Critical patent/ES2189905T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

SE DESCRIBE UN NUEVO PROCEDIMIENTO PARA LA PREPARACION DE 3 ALCOXI ONDE R SUP,1} ES UN GRUPO ALQUILO C SUB,1} PO ARILO Y R SUB,2} UN GRUPO ALCOXI C SUB,1} RUPO ARILOXI, PARTIENDO DE ACIDO AMINOMALONICO DINITRILO O DE AMINOACETONITRILO.
ES97111847T 1996-07-11 1997-07-11 Procedimiento para la preparacion de pirazin-2-aminas. Expired - Lifetime ES2189905T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH173996 1996-07-11
CH253996 1996-10-17

Publications (1)

Publication Number Publication Date
ES2189905T3 true ES2189905T3 (es) 2003-07-16

Family

ID=25688530

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97111847T Expired - Lifetime ES2189905T3 (es) 1996-07-11 1997-07-11 Procedimiento para la preparacion de pirazin-2-aminas.

Country Status (9)

Country Link
US (2) US5877319A (es)
EP (1) EP0820993B1 (es)
JP (1) JP4399870B2 (es)
AT (1) ATE231844T1 (es)
CA (1) CA2209465C (es)
DE (1) DE59709214D1 (es)
DK (1) DK0820993T3 (es)
ES (1) ES2189905T3 (es)
PT (1) PT820993E (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4660862B2 (ja) * 1997-07-03 2011-03-30 ロンザ リミテッド アルコキシピラジン誘導体の製造方法
JP2005320249A (ja) * 2002-05-01 2005-11-17 Banyu Pharmaceut Co Ltd ２−アミノピラジン誘導体の製造方法
BRPI0415863A (pt) * 2003-10-27 2007-01-09 Astellas Pharma Inc derivados pirazina e seus usos farmacêuticos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB922725A (en) * 1960-07-08 1963-04-03 Farmaceutici Italia Pyrazine derivatives
US4193995A (en) * 1972-05-05 1980-03-18 Merck Sharp & Dohme (I.A.) Corp. 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds and compositions
GB1471851A (en) * 1974-12-27 1977-04-27 Sagami Chem Res Diaminomaleonitrile derivatives and processes for preparing the same
US4211870A (en) * 1979-04-06 1980-07-08 Eli Lilly And Company Preparation of substituted 2-aminopyrazines
IL64267A (en) * 1980-12-09 1985-08-30 Erba Farmitalia Ethers of hydroxymethylpyrazin-n-oxides,their preparation and pharmaceutical compositions containing them
DE3242195A1 (de) * 1982-11-15 1984-05-17 Basf Ag, 6700 Ludwigshafen Neue 2-aminopyrazine und verfahren zur herstellung von 2-aminopyrazinen und pyrazinen

Also Published As

Publication number Publication date
JPH1067756A (ja) 1998-03-10
DE59709214D1 (de) 2003-03-06
PT820993E (pt) 2003-06-30
DK0820993T3 (da) 2003-05-05
CA2209465C (en) 2008-04-29
EP0820993B1 (de) 2003-01-29
ATE231844T1 (de) 2003-02-15
CA2209465A1 (en) 1998-01-11
US5877319A (en) 1999-03-02
EP0820993A3 (de) 1998-02-04
JP4399870B2 (ja) 2010-01-20
US5998618A (en) 1999-12-07
EP0820993A2 (de) 1998-01-28

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