ES2186916T3 - Derivados de isoxazolina como agentes antimicrobianos. - Google Patents

Derivados de isoxazolina como agentes antimicrobianos.

Info

Publication number
ES2186916T3
ES2186916T3 ES97937156T ES97937156T ES2186916T3 ES 2186916 T3 ES2186916 T3 ES 2186916T3 ES 97937156 T ES97937156 T ES 97937156T ES 97937156 T ES97937156 T ES 97937156T ES 2186916 T3 ES2186916 T3 ES 2186916T3
Authority
ES
Spain
Prior art keywords
antimicrobial agents
isoxazoline derivatives
isoxazoline
derivatives
national
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97937156T
Other languages
English (en)
Spanish (es)
Inventor
Michael R Barbachyn
Richard C Thomas
Gary J Cleek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Application granted granted Critical
Publication of ES2186916T3 publication Critical patent/ES2186916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
ES97937156T 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos. Expired - Lifetime ES2186916T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2428796P 1996-08-21 1996-08-21

Publications (1)

Publication Number Publication Date
ES2186916T3 true ES2186916T3 (es) 2003-05-16

Family

ID=21819822

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97937156T Expired - Lifetime ES2186916T3 (es) 1996-08-21 1997-08-15 Derivados de isoxazolina como agentes antimicrobianos.

Country Status (10)

Country Link
US (2) US5990136A (enExample)
EP (1) EP0920421B1 (enExample)
JP (1) JP2000516245A (enExample)
AT (1) ATE227277T1 (enExample)
AU (1) AU3973697A (enExample)
DE (1) DE69716925T2 (enExample)
DK (1) DK0920421T3 (enExample)
ES (1) ES2186916T3 (enExample)
PT (1) PT920421E (enExample)
WO (1) WO1998007708A1 (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
US6255304B1 (en) 1997-05-30 2001-07-03 Pharmacia & Upjohn Company Oxazolidinone antibacterial agents having a thiocarbonyl functionality
ES2242280T3 (es) 1997-05-30 2005-11-01 PHARMACIA & UPJOHN COMPANY LLC Agentes antibacterianos de oxazolidinona que contienen funcionalidad tiocarbonilo.
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
PT1054874E (pt) * 1998-02-13 2003-01-31 Upjohn Co Derivados de aminofenil-isoxazolina substituidos uteis como anti-microbianos
AU3180999A (en) * 1998-02-25 1999-09-15 Pharmacia & Upjohn Company Substituted aminomethyl isoxazoline derivatives useful as antimicrobials
ID30299A (id) 1998-06-05 2001-11-22 Astrazeneca Ab Turunan oksazolidinon, proses pembuatannya dan komposisi farmasi yang mengandungnya
US6420349B1 (en) 1998-08-24 2002-07-16 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
TW572757B (en) * 1998-08-24 2004-01-21 Bristol Myers Squibb Co Novel isoxazolinone antibacterial agents
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
US6465456B2 (en) 2000-06-29 2002-10-15 Bristol-Myers Squibb Company Isoxazolinone antibacterial agents
JP2004518677A (ja) 2000-12-21 2004-06-24 ファルマシア・アンド・アップジョン・カンパニー 抗菌性キノロン誘導体および細菌感染を治療するためのその使用
EP1357104A4 (en) * 2000-12-26 2004-07-28 Res Found Itsuu Lab TROPOLONE DERIVATIVE
JP2005512975A (ja) * 2001-10-25 2005-05-12 アストラゼネカ アクチボラグ 抗菌薬として有用なイソキサゾリン誘導体
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados
US7141588B2 (en) * 2002-02-25 2006-11-28 Pfizer, Inc. N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
JP2006516989A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤として使用するための二環式環によりｎ−置換されたオキサゾリジノン誘導体
CA2515311A1 (en) * 2003-02-07 2004-08-19 Warner-Lambert Company Llc Antibacterial agents
US7304050B2 (en) * 2003-09-16 2007-12-04 Pfizer Inc. Antibacterial agents
WO2005082900A2 (en) * 2004-01-28 2005-09-09 Pharmacia & Upjohn Company Llc Oxazolidinone amidoximes as antibacterial agents
AU2005270951A1 (en) * 2004-08-06 2006-02-16 Pharmacia & Upjohn Company Llc Oxazolidinones containing oxindoles as antibacterial agents
CA2579199C (en) * 2004-09-10 2013-04-30 Syngenta Limited Substituted isoxazoles as fungicides
BR112013002871B1 (pt) * 2010-08-05 2018-11-21 Zoetis Llc derivados de isoxazolina, seu uso e composição farmacêutica ou veterinária
JP5918264B2 (ja) 2010-12-22 2016-05-18 アッヴィ・インコーポレイテッド Ｃ型肝炎阻害剤およびその使用
US9938816B2 (en) * 2012-10-03 2018-04-10 Shell Oil Company Optimizing performance of a drilling assembly
WO2021000297A1 (en) * 2019-07-03 2021-01-07 Merck Sharp & Dohme Corp. Compounds and methods of use thereof as antibacterial agents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL137326C (enExample) * 1967-08-26
US4283403A (en) * 1976-06-14 1981-08-11 Eli Lilly And Company Substituted isoxazolines for control of plant phytopathogens
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE69316240T2 (de) * 1992-12-08 1998-05-20 Upjohn Co Durch eine tropon gruppe substituierte phenyloxazolidinone-derivate als antibakterielles mittel
PT730587E (pt) * 1993-11-26 2000-05-31 Pfizer 3-aril-2-isoxazolinas como agentes anti-inflamatorios
DE4425613A1 (de) * 1994-07-20 1996-01-25 Bayer Ag 5-gliedrige Heteroaryl-oxazolidinone
DE4425612A1 (de) * 1994-07-20 1996-04-04 Bayer Ag 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone
US5710159A (en) * 1996-05-09 1998-01-20 The Dupont Merck Pharmaceutical Company Integrin receptor antagonists

Also Published As

Publication number Publication date
DE69716925D1 (de) 2002-12-12
EP0920421A1 (en) 1999-06-09
US5990136A (en) 1999-11-23
EP0920421B1 (en) 2002-11-06
JP2000516245A (ja) 2000-12-05
AU3973697A (en) 1998-03-06
US6093736A (en) 2000-07-25
DE69716925T2 (de) 2003-09-11
WO1998007708A1 (en) 1998-02-26
PT920421E (pt) 2003-03-31
ATE227277T1 (de) 2002-11-15
DK0920421T3 (da) 2003-03-10

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