ES2186889T3 - Sistema de linea celular de marcado que permite detectar la presencia de citomegalovirus e identificar moduladores de la expresion de genes virales. - Google Patents
Sistema de linea celular de marcado que permite detectar la presencia de citomegalovirus e identificar moduladores de la expresion de genes virales.Info
- Publication number
- ES2186889T3 ES2186889T3 ES97920178T ES97920178T ES2186889T3 ES 2186889 T3 ES2186889 T3 ES 2186889T3 ES 97920178 T ES97920178 T ES 97920178T ES 97920178 T ES97920178 T ES 97920178T ES 2186889 T3 ES2186889 T3 ES 2186889T3
- Authority
- ES
- Spain
- Prior art keywords
- citomegalovirus
- detect
- allows
- cell line
- line system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
ESTA INVENCION SE REFIERE A UNAS LINEAS CELULARES Y A UNOS PROCEDIMIENTOS PARA DETECTAR UNA INFECCION POR CITOMEGALOVIRUS Y PARA IDENTIFICAR MODULADORES DE EXPRESION GENICA DE CITOMEGALOVIRUS. LAS LINEAS CELULARES LLEVAN UN PLASMIDO INTEGRADO QUE CONTIENE UN GEN DE INFORMANTE BAJO EL CONTROL DE UN PROMOTOR DE CITOMEGALOVIRUS. SE PUEDEN UTILIZAR DICHAS LINEAS CELULARES, POR EJEMPLO, PARA IDENTIFICAR ESPECIFICAMENTE UNA INFECCION DE HCMV EN UNA MUESTRA BIOLOGICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/630,182 US5945276A (en) | 1996-04-10 | 1996-04-10 | Reporter cell line system for detecting cytomegalovirus and identifying modulators of viral gene expression |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2186889T3 true ES2186889T3 (es) | 2003-05-16 |
Family
ID=24526131
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97920178T Expired - Lifetime ES2186889T3 (es) | 1996-04-10 | 1997-04-08 | Sistema de linea celular de marcado que permite detectar la presencia de citomegalovirus e identificar moduladores de la expresion de genes virales. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5945276A (es) |
EP (1) | EP0954613B1 (es) |
JP (1) | JP2000508173A (es) |
AT (1) | ATE224459T1 (es) |
AU (1) | AU720485B2 (es) |
CA (1) | CA2250967A1 (es) |
DE (1) | DE69715672T2 (es) |
ES (1) | ES2186889T3 (es) |
WO (1) | WO1997038139A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1209875A (zh) * | 1996-01-26 | 1999-03-03 | 维科公司 | 根据人类hiv病毒株的表型药物敏感性控制hiv阳性病人化疗的方法 |
US5955275A (en) | 1997-02-14 | 1999-09-21 | Arcaris, Inc. | Methods for identifying nucleic acid sequences encoding agents that affect cellular phenotypes |
US6623922B1 (en) | 1997-02-14 | 2003-09-23 | Deltagen Proteomics | Methods for identifying, characterizing, and evolving cell-type specific CIS regulatory elements |
WO2001007061A1 (en) * | 1999-07-27 | 2001-02-01 | Smithkline Beecham Corporation | Whole cell assay |
DE10119428A1 (de) * | 2001-04-20 | 2002-10-24 | Enron Wind Gmbh | Grundrahmen zur Anordnung der Welle des Rotors einer Windkraftanlage an deren Turm |
JP5712513B2 (ja) * | 2010-07-07 | 2015-05-07 | 富士レビオ株式会社 | ヒトサイトメガロウイルス感染の検出方法 |
EP2956557B1 (en) * | 2013-02-14 | 2018-07-11 | The J. David Gladstone Institutes | Compositions and methods of use thereof for identifying anti-viral agents |
CN116948988A (zh) | 2016-01-29 | 2023-10-27 | 西里昂生物技术有限责任公司 | 基于aav的条件表达系统 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5168062A (en) * | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US5070012A (en) * | 1988-03-30 | 1991-12-03 | The Board Of Trustees Of The Leland Stanford Junior University | Monitoring of cells and trans-activating transcription elements |
US5776502A (en) * | 1989-07-18 | 1998-07-07 | Oncogene Science, Inc. | Methods of transcriptionally modulating gene expression |
WO1992012635A1 (en) * | 1991-01-18 | 1992-08-06 | Oncogene Science, Inc. | Methods of transcriptionally modulating gene expression of viral genes and other genes |
GB9114437D0 (en) * | 1991-07-03 | 1991-08-21 | Health Lab Service Board | Recombinant adenoviruses and the use thereof for detecting the presence in eukaryotic cells of the expression products of specific genes |
SG49046A1 (en) * | 1991-07-05 | 1998-05-18 | American Cyanamid Co | Method for identifying non-essential genes of the human cytomegalovirus genome and for screening for inhibitors of human cytomegaloverirus |
US5418132A (en) * | 1992-06-18 | 1995-05-23 | Washington University | Genetically engineered cell line for detecting infectious herpes simplex virus and method therefore |
US5591579A (en) * | 1993-12-21 | 1997-01-07 | Washington University | Indicator cell line for detecting RNA viruses and method therefor |
-
1996
- 1996-04-10 US US08/630,182 patent/US5945276A/en not_active Expired - Fee Related
-
1997
- 1997-04-08 AT AT97920178T patent/ATE224459T1/de not_active IP Right Cessation
- 1997-04-08 ES ES97920178T patent/ES2186889T3/es not_active Expired - Lifetime
- 1997-04-08 EP EP97920178A patent/EP0954613B1/en not_active Expired - Lifetime
- 1997-04-08 WO PCT/US1997/005713 patent/WO1997038139A1/en active IP Right Grant
- 1997-04-08 JP JP9536398A patent/JP2000508173A/ja active Pending
- 1997-04-08 DE DE69715672T patent/DE69715672T2/de not_active Expired - Fee Related
- 1997-04-08 CA CA002250967A patent/CA2250967A1/en not_active Abandoned
- 1997-04-08 AU AU24439/97A patent/AU720485B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JP2000508173A (ja) | 2000-07-04 |
CA2250967A1 (en) | 1997-10-16 |
DE69715672T2 (de) | 2003-05-22 |
EP0954613A1 (en) | 1999-11-10 |
EP0954613B1 (en) | 2002-09-18 |
AU720485B2 (en) | 2000-06-01 |
DE69715672D1 (de) | 2002-10-24 |
US5945276A (en) | 1999-08-31 |
ATE224459T1 (de) | 2002-10-15 |
AU2443997A (en) | 1997-10-29 |
WO1997038139A1 (en) | 1997-10-16 |
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