MX9600860A - Metodo para detectar polimorfismo de gen p4501a2 de citocromo humano. - Google Patents

Metodo para detectar polimorfismo de gen p4501a2 de citocromo humano.

Info

Publication number
MX9600860A
MX9600860A MX9600860A MX9600860A MX9600860A MX 9600860 A MX9600860 A MX 9600860A MX 9600860 A MX9600860 A MX 9600860A MX 9600860 A MX9600860 A MX 9600860A MX 9600860 A MX9600860 A MX 9600860A
Authority
MX
Mexico
Prior art keywords
detecting human
human cytochrome
gene polymorphism
gene
cypia2
Prior art date
Application number
MX9600860A
Other languages
English (en)
Inventor
Fukui Takafumi
Katsuragi Kiyonori
Kinoshita Moritoshi
Shin Sadahito
Shin Kenkoo
Shin Junna
Kim Sadae
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of MX9600860A publication Critical patent/MX9600860A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente invencion provee un método para detectar polimorfismo del gen P45U01A2 (CYP1A2) de citocromo humano en el cual la substitucion en una 2064?? base, y/o supresion de una -1569?? base en una region sin traduccion del gen P45O1A2 de citocromo humano son/es detectada. De conformidad con el método de la invencion, se pueden detectar nuevos tipos de polimorfismo de gen CYP1A2 simplemente y fácilmente con alta sensibilidad y precision, y el método requiere solo de una pequeña cantidad de una muestra de ADN.
MX9600860A 1994-07-06 1995-07-06 Metodo para detectar polimorfismo de gen p4501a2 de citocromo humano. MX9600860A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15457194 1994-07-06
PCT/JP1995/001352 WO1996001328A1 (fr) 1994-07-06 1995-07-06 Procede de detection de polymorphisme des genes du cytochrome humain p4501a2

Publications (1)

Publication Number Publication Date
MX9600860A true MX9600860A (es) 1997-12-31

Family

ID=15587146

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9600860A MX9600860A (es) 1994-07-06 1995-07-06 Metodo para detectar polimorfismo de gen p4501a2 de citocromo humano.

Country Status (7)

Country Link
US (1) US5719026A (es)
EP (1) EP0723021A1 (es)
KR (1) KR960704069A (es)
CN (1) CN1151188A (es)
CA (1) CA2170052A1 (es)
MX (1) MX9600860A (es)
WO (1) WO1996001328A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6528260B1 (en) 1999-03-25 2003-03-04 Genset, S.A. Biallelic markers related to genes involved in drug metabolism
EP1218537B1 (en) * 1999-03-25 2008-09-10 Serono Genetics Institute S.A. Biallelic markers related to genes involved in drug metabolism
US6596489B2 (en) 2001-03-30 2003-07-22 Applied Gene Technologies Methods and compositions for analyzing nucleotide sequence mismatches using RNase H
CN100434438C (zh) * 2006-07-28 2008-11-19 哈尔滨医科大学 一种cyp1a2多肽
WO2008032921A1 (en) * 2006-09-11 2008-03-20 Inje University Industry-Academic Cooperation Foundation Htsnps for determining a genotype of cytochrome p450 1a2, 2a6 and 2d6, pxr and udp-glucuronosyltransferase 1a gene and multiplex genotyping methods using thereof
KR100973049B1 (ko) * 2006-09-11 2010-07-29 인제대학교 산학협력단 사이토크롬 피450 2디6 유전자의 유전형 분석을 위한해플로타입 마커 단일염기변이 및 이를 이용한 유전자분석칩
CN106222281A (zh) * 2016-08-10 2016-12-14 中南大学湘雅三医院 基于基因多态性指导儿童患者精准用药的试剂盒、应用和方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9001181D0 (en) * 1990-01-18 1990-03-21 Imp Cancer Res Tech Genetic assay
ES2103756T3 (es) * 1990-06-22 1997-10-01 Hoffmann La Roche Deteccion de metabolizadores ineficaces de farmacos.

Also Published As

Publication number Publication date
US5719026A (en) 1998-02-17
WO1996001328A1 (fr) 1996-01-18
CN1151188A (zh) 1997-06-04
KR960704069A (ko) 1996-08-31
CA2170052A1 (en) 1996-01-18
EP0723021A1 (en) 1996-07-24

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