ES2185712T3 - Procedimientos y equipos de analisis para el diagnostico especifico y sensible de las enfermedades periodontales. - Google Patents

Procedimientos y equipos de analisis para el diagnostico especifico y sensible de las enfermedades periodontales.

Info

Publication number
ES2185712T3
ES2185712T3 ES95928517T ES95928517T ES2185712T3 ES 2185712 T3 ES2185712 T3 ES 2185712T3 ES 95928517 T ES95928517 T ES 95928517T ES 95928517 T ES95928517 T ES 95928517T ES 2185712 T3 ES2185712 T3 ES 2185712T3
Authority
ES
Spain
Prior art keywords
periodontal diseases
equipment
specific
analysis procedures
sensitive diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95928517T
Other languages
English (en)
Inventor
Timo Arto Sorsa
Sari Hannele Tikanoja
Leila Christina Lundqvist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medix Biochemica Oy AB
Original Assignee
Medix Biochemica Oy AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medix Biochemica Oy AB filed Critical Medix Biochemica Oy AB
Application granted granted Critical
Publication of ES2185712T3 publication Critical patent/ES2185712T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24034—Neutrophil collagenase (3.4.24.34)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/974—Aids related test
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/909—Nephelometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)

Abstract

LA INVENCION PRESENTA METODOS Y EQUIPOS DE PRUEBA QUE SUMINISTRAN LOS MEDIOS PARA LA VALORACION FACIL, SENSIBLE Y SELECTIVA DE LA ACTIVIDAD DE ENFERMEDADES PERIODONTALES, PERIIMPLANTITIS O DE ENFERMEDADES PERIODONTALES RELACIONADAS CON LA INFECCION POR EL HIV (+) O CON LA ENFERMEDAD DEL SIDA. LOS METODOS PREFERIDOS Y LOS EQUIPOS DE PRUEBA MAS ADECUADOS SON CONSTRUIDOS PARA EFECTUAR PRUEBAS AMBULATORIAS Y FACILES. LA INVENCION SE BASA EN LA PREPARACION Y EL USO DE ANTICUERPOS MONOCLONALES QUE RECONOCEN LA METALOPROTEINASA-8 DE MATRIZ DE MAMIFERO ACTIVA (MMP-8) Y ES CAPAZ DE DIFERENCIAR ENTRE LA METALOPROTEINASA-8 DE MATRIZ Y ACTIVA Y SU PROFORMA INACTIVA.
ES95928517T 1994-08-26 1995-08-18 Procedimientos y equipos de analisis para el diagnostico especifico y sensible de las enfermedades periodontales. Expired - Lifetime ES2185712T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI943939A FI98961C (fi) 1994-08-26 1994-08-26 Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi

Publications (1)

Publication Number Publication Date
ES2185712T3 true ES2185712T3 (es) 2003-05-01

Family

ID=8541255

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95928517T Expired - Lifetime ES2185712T3 (es) 1994-08-26 1995-08-18 Procedimientos y equipos de analisis para el diagnostico especifico y sensible de las enfermedades periodontales.

Country Status (12)

Country Link
US (1) US5736341A (es)
EP (1) EP0777859B1 (es)
JP (1) JP3083325B2 (es)
KR (1) KR100255086B1 (es)
AT (1) ATE229184T1 (es)
AU (1) AU690316B2 (es)
CA (1) CA2197452A1 (es)
DE (1) DE69529076T2 (es)
ES (1) ES2185712T3 (es)
FI (1) FI98961C (es)
NO (1) NO970827L (es)
WO (1) WO1996007103A1 (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2158102T3 (es) * 1995-04-12 2001-09-01 Medix Biochemica Ab Oy Procedimientos y equipos de ensayo para la diagnosis de enfermedades periodontales y para la prediccion del riesgo de progresion de las mismas.
AUPO652897A0 (en) * 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US6143506A (en) * 1998-08-13 2000-11-07 The Research Foundation Of State Of Ny Diagnostic method for detection of periodontitis or peri-implantitis
FI990888A0 (fi) * 1999-04-20 1999-04-20 Medix Biochemica Ab Oy Menetelmä ja testikittejä respiratorisen alueen tulehduksen läsnäolon ja vaikeusasteen arvioimiseksi
DE19926728B4 (de) 1999-06-11 2011-08-18 3M Espe Ag, 82229 Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
FI20000422A (fi) * 2000-02-23 2001-08-23 Medix Biochemica Ab Oy Menetelmä ja testipakkaus pitkäaikaisten epäonnistumisten välttämiseksi juurikanavahoidossa
JP2003532896A (ja) * 2000-05-12 2003-11-05 ロダリス・ファーマシューティカルズ・リミテッド Ｉｐｇアッセイ
EP1282823B1 (en) * 2000-05-17 2014-05-07 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Proteolytic enzymes for the diagnosis of kidney disorders
KR100425525B1 (ko) * 2000-11-21 2004-03-30 재단법인서울대학교산학협력재단 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트
DE10061195B4 (de) 2000-12-08 2004-12-02 3M Espe Ag Verwendung von Abformmassen zur Herstellung von Behandlungsvorrichtungen
US7041787B2 (en) * 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors
US20030119073A1 (en) * 2001-12-21 2003-06-26 Stephen Quirk Sensors and methods of detection for proteinase enzymes
AU2004227999B2 (en) 2003-04-01 2009-09-24 Proactive Oral Solutions, Inc. Caries risk test for predicting and assessing the risk of disease
SE0400191D0 (sv) * 2004-01-30 2004-01-30 Tendera Ab A test kit for detecting periodontal disease
WO2006031377A2 (en) * 2004-08-24 2006-03-23 Searete Llc A system and method related to enhancing an immune system
KR101485303B1 (ko) * 2006-09-21 2015-01-22 네스텍 소시에테아노님 희귀 순환세포 내의 다수의 신호전달인자를 검출하기 위한 항체 기반 분석법
BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
ES2526211T3 (es) 2007-07-13 2015-01-08 Nestec S.A. Selección de fármacos para la terapia del cáncer de pulmón utilizando matrices basadas en anticuerpos
US9002654B2 (en) * 2007-07-30 2015-04-07 The Regents Of The University Of Michigan Multi-analyte analysis of saliva biomarkers as predictors of periodontal and pre-implant disease
NZ617520A (en) 2008-02-25 2015-05-29 Nestec Sa Drug selection for breast cancer therapy using antibody-based arrays
TWI405565B (zh) * 2009-04-01 2013-08-21 Colgate Palmolive Co 口腔用組成物之抗－骨質流失及抗－牙周附連喪失之功效
JP5795311B2 (ja) 2009-07-15 2015-10-14 ネステク ソシエテ アノニム 抗体ベースのアレイを使用する胃癌療法のための薬物選択
JP2011232320A (ja) * 2009-10-01 2011-11-17 Sony Corp 生体内物質検出用プローブ、および該生体内物質検出用プローブを用いた生体内物質検出装置
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
WO2012020122A1 (en) * 2010-08-13 2012-02-16 Dentognostics Gmbh Process for avoiding false positive results in a detecting process of an inflammation indicator in a rinse solution for taking up gingival crevicular fluid
GB201018602D0 (en) 2010-11-04 2010-12-22 Vib Vzw MMP8 inactivating antigen binding proteins
US9719995B2 (en) 2011-02-03 2017-08-01 Pierian Holdings, Inc. Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
PT2691530T (pt) 2011-06-10 2018-05-10 Univ Oregon Health & Science Glicoproteínas e vectores recombinantes cmv
KR101851425B1 (ko) 2011-09-02 2018-04-23 네스텍 소시에테아노님 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
FI127924B (en) * 2014-02-27 2019-05-31 Oy Medix Biochemica Ab METHOD OF MEASURING MMP-8 ACTIVATION
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
WO2018215528A1 (en) * 2017-05-24 2018-11-29 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis based on salivary il-1beta and mmp-9
CN110730909A (zh) * 2017-05-24 2020-01-24 皇家飞利浦有限公司 基于唾液的hgf以及mmp-8的牙周炎的诊断
KR102161733B1 (ko) 2017-09-07 2020-10-05 인천대학교 산학협력단 자성비드 및 분자비컨을 이용한 엑소좀의 다중검출방법
CN113383235A (zh) * 2018-12-26 2021-09-10 高露洁-棕榄公司 作为牙龈炎诊断物的中性粒细胞失调的生物标志物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5280106A (en) * 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
US5324634A (en) * 1992-03-31 1994-06-28 The Research Foundation Of State University Of New York Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer

Also Published As

Publication number Publication date
KR970705753A (ko) 1997-10-09
DE69529076T2 (de) 2003-07-10
FI98961B (fi) 1997-05-30
FI943939A0 (fi) 1994-08-26
EP0777859B1 (en) 2002-12-04
JP3083325B2 (ja) 2000-09-04
AU690316B2 (en) 1998-04-23
US5736341A (en) 1998-04-07
CA2197452A1 (en) 1996-03-07
NO970827L (no) 1997-04-14
KR100255086B1 (ko) 2000-06-01
DE69529076D1 (de) 2003-01-16
FI98961C (fi) 1997-09-10
WO1996007103A1 (en) 1996-03-07
AU3225195A (en) 1996-03-22
NO970827D0 (no) 1997-02-24
JPH10501070A (ja) 1998-01-27
FI943939A (fi) 1996-02-27
ATE229184T1 (de) 2002-12-15
EP0777859A1 (en) 1997-06-11

Similar Documents

Publication Publication Date Title
ES2185712T3 (es) Procedimientos y equipos de analisis para el diagnostico especifico y sensible de las enfermedades periodontales.
Caraher et al. Flow cytometric analysis of intracellular IFN-γ, IL-4 and IL-10 in CD3+ 4+ T-cells from rat spleen
ATE77488T1 (de) In-vitro-testverfahren zum nachweis zellulaerer immunresponsen.
PT91590A (pt) Metodo para analisar biopolimeros por meio de hibridacao in situ
EP0314402A3 (en) Monoclonal antibodies against human interleukin-4 and hybridomas producing the same
DK0419387T3 (da) Hidtil ukendte hydrofile derivater, terapeutisk og diagnostisk anvendelse, diagnostiske eller terapeutiske kit og immunologiske reagenser
ATE268904T1 (de) Zellbasiertes festphasentest
ATE245699T1 (de) Rekombinant pgp3, verfahren zu dessen herstellung,und dessen verwendung in der diagnose und therapie
JPS5463796A (en) Method and device for inbitro clinical testing through solidus analysis system
DK0564494T3 (da) Testmetode og reagenssæt dertil
HUP0102496A2 (hu) Haemophilus parasuis vakcina és diagnosztikum
PT946874E (pt) Diagnostico de helicobacter pylori
ES8606948A1 (es) Mejoras intruducidas en un ensayo para determinar un antigeno bacteriano en una muestra de ensayo
IT7883478A0 (it) Dispositivo ultrasonico per il collaudo non distruttivo disuperfici di coesione.
ATE92770T1 (de) Mittel zum nachweis einer fibrinolytischen wirkung.
IT1106734B (it) Metodo e dispositivo per la produzione microbiologica di proteinada organisni unicellulari mediante l impiego di alcool etilico
DK414386A (da) Monoklonalt antistof, cellelinje til fremstilling deraf og antistoffets anvendelse
ES2121756T3 (es) Analisis enzimatico y equipo de analisis para medir la activacion celular.
PT1222311E (pt) Teste de helicase por electroquimioluminescencia
JPS51144293A (en) Continuous analysis system of urine, etc
NO963911D0 (no) Innretning for behandling av autoimmune sykdommer og fremgangsmåte for behandling
IT1065245B (it) Reagente per l analisi di trigli ceridi e metodo per la sua utilizzazione
FR2273280A1 (en) Measurement of antigens and antibodies - in biological fluids by immuno diffusion techniques with antibodies marked with enzymes
JPS5386014A (en) Quantitative analysis of antigen and antibody
UA51418A (uk) Спосіб діагностики стану системи фібринолізу