DE69529076T2 - Verfahren und testsätze zur spezifischen und empfindlichen diagnose periodontaler erkrankungen - Google Patents

Verfahren und testsätze zur spezifischen und empfindlichen diagnose periodontaler erkrankungen

Info

Publication number
DE69529076T2
DE69529076T2 DE69529076T DE69529076T DE69529076T2 DE 69529076 T2 DE69529076 T2 DE 69529076T2 DE 69529076 T DE69529076 T DE 69529076T DE 69529076 T DE69529076 T DE 69529076T DE 69529076 T2 DE69529076 T2 DE 69529076T2
Authority
DE
Germany
Prior art keywords
periodontal diseases
specific
test sets
sensitive diagnosis
matrix metalloproteinase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69529076T
Other languages
English (en)
Other versions
DE69529076D1 (de
Inventor
Arto Sorsa
Hannele Tikanoja
Christina Lundqvist
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dentognostics GmbH
Original Assignee
MEDIX BIOCHEMICA KAUNIAINEN Oy AB
Medix Biochemica Oy AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MEDIX BIOCHEMICA KAUNIAINEN Oy AB, Medix Biochemica Oy AB filed Critical MEDIX BIOCHEMICA KAUNIAINEN Oy AB
Application granted granted Critical
Publication of DE69529076D1 publication Critical patent/DE69529076D1/de
Publication of DE69529076T2 publication Critical patent/DE69529076T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24034—Neutrophil collagenase (3.4.24.34)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/974—Aids related test
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808—Automated or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/819—Multifunctional antigen or antibody
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/909—Nephelometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
DE69529076T 1994-08-26 1995-08-18 Verfahren und testsätze zur spezifischen und empfindlichen diagnose periodontaler erkrankungen Expired - Lifetime DE69529076T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI943939A FI98961C (fi) 1994-08-26 1994-08-26 Menetelmät ja määritysvälineet parodontaalisairauden aktiivisuuden ja/tai peri-implantiitin ja/tai niiden kohonneen riskin diagnosoimiseksi
PCT/FI1995/000437 WO1996007103A1 (en) 1994-08-26 1995-08-18 Methods and test kits for specific and sensitive diagnosing of periodontal diseases

Publications (2)

Publication Number Publication Date
DE69529076D1 DE69529076D1 (de) 2003-01-16
DE69529076T2 true DE69529076T2 (de) 2003-07-10

Family

ID=8541255

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69529076T Expired - Lifetime DE69529076T2 (de) 1994-08-26 1995-08-18 Verfahren und testsätze zur spezifischen und empfindlichen diagnose periodontaler erkrankungen

Country Status (12)

Country Link
US (1) US5736341A (de)
EP (1) EP0777859B1 (de)
JP (1) JP3083325B2 (de)
KR (1) KR100255086B1 (de)
AT (1) ATE229184T1 (de)
AU (1) AU690316B2 (de)
CA (1) CA2197452A1 (de)
DE (1) DE69529076T2 (de)
ES (1) ES2185712T3 (de)
FI (1) FI98961C (de)
NO (1) NO970827L (de)
WO (1) WO1996007103A1 (de)

Families Citing this family (42)

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ES2158102T3 (es) * 1995-04-12 2001-09-01 Medix Biochemica Ab Oy Procedimientos y equipos de ensayo para la diagnosis de enfermedades periodontales y para la prediccion del riesgo de progresion de las mismas.
AUPO652897A0 (en) * 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
US6143506A (en) * 1998-08-13 2000-11-07 The Research Foundation Of State Of Ny Diagnostic method for detection of periodontitis or peri-implantitis
FI990888A0 (fi) * 1999-04-20 1999-04-20 Medix Biochemica Ab Oy Menetelmä ja testikittejä respiratorisen alueen tulehduksen läsnäolon ja vaikeusasteen arvioimiseksi
DE19926728B4 (de) 1999-06-11 2011-08-18 3M Espe Ag, 82229 Verwendung von Trägermaterialien und diagnostisch nutzbaren Zusatzstoffen in Abbildungsverfahren für intraorale Diagnosezwecke
FI20000422A (fi) * 2000-02-23 2001-08-23 Medix Biochemica Ab Oy Menetelmä ja testipakkaus pitkäaikaisten epäonnistumisten välttämiseksi juurikanavahoidossa
JP2003532896A (ja) * 2000-05-12 2003-11-05 ロダリス・ファーマシューティカルズ・リミテッド Ｉｐｇアッセイ
EP1282823B1 (de) * 2000-05-17 2014-05-07 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Proteolytische enzyme zur diagnose von nierenerkrankungen
KR100425525B1 (ko) * 2000-11-21 2004-03-30 재단법인서울대학교산학협력재단 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트
DE10061195B4 (de) 2000-12-08 2004-12-02 3M Espe Ag Verwendung von Abformmassen zur Herstellung von Behandlungsvorrichtungen
US7041787B2 (en) * 2000-12-29 2006-05-09 Kimberly-Clark Worldwide, Inc. Design and use of advanced zinc chelating peptides to regulate matrix metalloproteinases
US6600057B2 (en) 2000-12-29 2003-07-29 Kimberly-Clark Worldwide, Inc. Matrix metalloproteinase inhibitors
US20030119073A1 (en) * 2001-12-21 2003-06-26 Stephen Quirk Sensors and methods of detection for proteinase enzymes
AU2004227999B2 (en) 2003-04-01 2009-09-24 Proactive Oral Solutions, Inc. Caries risk test for predicting and assessing the risk of disease
SE0400191D0 (sv) * 2004-01-30 2004-01-30 Tendera Ab A test kit for detecting periodontal disease
WO2006031377A2 (en) * 2004-08-24 2006-03-23 Searete Llc A system and method related to enhancing an immune system
KR101485303B1 (ko) * 2006-09-21 2015-01-22 네스텍 소시에테아노님 희귀 순환세포 내의 다수의 신호전달인자를 검출하기 위한 항체 기반 분석법
BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
ES2526211T3 (es) 2007-07-13 2015-01-08 Nestec S.A. Selección de fármacos para la terapia del cáncer de pulmón utilizando matrices basadas en anticuerpos
US9002654B2 (en) * 2007-07-30 2015-04-07 The Regents Of The University Of Michigan Multi-analyte analysis of saliva biomarkers as predictors of periodontal and pre-implant disease
NZ617520A (en) 2008-02-25 2015-05-29 Nestec Sa Drug selection for breast cancer therapy using antibody-based arrays
TWI405565B (zh) * 2009-04-01 2013-08-21 Colgate Palmolive Co 口腔用組成物之抗－骨質流失及抗－牙周附連喪失之功效
JP5795311B2 (ja) 2009-07-15 2015-10-14 ネステク ソシエテ アノニム 抗体ベースのアレイを使用する胃癌療法のための薬物選択
JP2011232320A (ja) * 2009-10-01 2011-11-17 Sony Corp 生体内物質検出用プローブ、および該生体内物質検出用プローブを用いた生体内物質検出装置
EP2550362B1 (de) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv-glycoproteine und rekombinante vektoren
WO2012020122A1 (en) * 2010-08-13 2012-02-16 Dentognostics Gmbh Process for avoiding false positive results in a detecting process of an inflammation indicator in a rinse solution for taking up gingival crevicular fluid
GB201018602D0 (en) 2010-11-04 2010-12-22 Vib Vzw MMP8 inactivating antigen binding proteins
US9719995B2 (en) 2011-02-03 2017-08-01 Pierian Holdings, Inc. Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
PT2691530T (pt) 2011-06-10 2018-05-10 Univ Oregon Health & Science Glicoproteínas e vectores recombinantes cmv
KR101851425B1 (ko) 2011-09-02 2018-04-23 네스텍 소시에테아노님 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링
US20130189754A1 (en) 2011-09-12 2013-07-25 International Aids Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
EP2873423B1 (de) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
FI127924B (en) * 2014-02-27 2019-05-31 Oy Medix Biochemica Ab METHOD OF MEASURING MMP-8 ACTIVATION
EP3069730A3 (de) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
EP3072901A1 (de) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Lösliche hiv-1-hüllglykoproteintrimere
WO2018215528A1 (en) * 2017-05-24 2018-11-29 Koninklijke Philips N.V. Diagnostics of mild or advanced periodontitis based on salivary il-1beta and mmp-9
CN110730909A (zh) * 2017-05-24 2020-01-24 皇家飞利浦有限公司 基于唾液的hgf以及mmp-8的牙周炎的诊断
KR102161733B1 (ko) 2017-09-07 2020-10-05 인천대학교 산학협력단 자성비드 및 분자비컨을 이용한 엑소좀의 다중검출방법
CN113383235A (zh) * 2018-12-26 2021-09-10 高露洁-棕榄公司 作为牙龈炎诊断物的中性粒细胞失调的生物标志物

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US5280106A (en) * 1988-05-20 1994-01-18 Liotta Lance A Matrix metalloproteinase peptides: role in diagnosis and therapy
US5324634A (en) * 1992-03-31 1994-06-28 The Research Foundation Of State University Of New York Diagnostic tests measuring gelatinase/inhibitor complexes for detection of aggressive and metastatic cancer

Also Published As

Publication number Publication date
KR970705753A (ko) 1997-10-09
FI98961B (fi) 1997-05-30
FI943939A0 (fi) 1994-08-26
EP0777859B1 (de) 2002-12-04
JP3083325B2 (ja) 2000-09-04
AU690316B2 (en) 1998-04-23
US5736341A (en) 1998-04-07
CA2197452A1 (en) 1996-03-07
NO970827L (no) 1997-04-14
KR100255086B1 (ko) 2000-06-01
DE69529076D1 (de) 2003-01-16
ES2185712T3 (es) 2003-05-01
FI98961C (fi) 1997-09-10
WO1996007103A1 (en) 1996-03-07
AU3225195A (en) 1996-03-22
NO970827D0 (no) 1997-02-24
JPH10501070A (ja) 1998-01-27
FI943939A (fi) 1996-02-27
ATE229184T1 (de) 2002-12-15
EP0777859A1 (de) 1997-06-11

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Owner name: DENTOGNOSTICS GMBH, 07745 JENA, DE

8380 Miscellaneous part iii

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