ES2185183T3 - Procedimiento para la preparacion de trifluormetilacetofenona. - Google Patents

Procedimiento para la preparacion de trifluormetilacetofenona.

Info

Publication number
ES2185183T3
ES2185183T3 ES98933622T ES98933622T ES2185183T3 ES 2185183 T3 ES2185183 T3 ES 2185183T3 ES 98933622 T ES98933622 T ES 98933622T ES 98933622 T ES98933622 T ES 98933622T ES 2185183 T3 ES2185183 T3 ES 2185183T3
Authority
ES
Spain
Prior art keywords
compound
preparation
formula
trifluormetilacetofenona
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98933622T
Other languages
English (en)
Inventor
Adriano Indolese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2185183T3 publication Critical patent/ES2185183T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/12—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the ring of aromatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/516—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of nitrogen-containing compounds to >C = O groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Se presenta un procedimiento para la preparación de un compuesto de la fórmula (I), en la que Y es un grupo que es inerte para las reacciones, preferiblemente hidrocarbilo; y m vale entre 0 y 4, preferiblemente 0; en el procedimiento a) un compuesto de la fórmula (II), en la que X es cloro, bromo o yodo, preferiblemente bromo, e Y y m son según se han definido en la fórmula (I), se hacen reaccionar con un viniléter de la fórmula (IIIa) o un enamido de la fórmula (IIIb): CH{sub,2} = CH-OR{sub,1} (IIIa) CH{sub,2} = CH-N(R{sub,2})-CO-R{sub,3} (IIIb), en donde R{sub,1} y R{sub,2} son independientemente alquilo C{sub,1-8}, alquenilo C{sub,1-8}, alcoxialquilo C{sub,1-8}, cicloalquilo C{sub,3-6}, fenilalquilo C{sub,1-2} o acilo C{sub,1-8}, los grupos están opcionalmente sustituidos, R{sub,3} es alquilo C{sub,1-8}, alquenilo C{sub,2-8}, alcoxialquilo C{sub,1-8}, cicloalquilo C{sub,3-6} o fenilalquilo C{sub,1-2}, los grupos están opcionalmente sustituidos, en un solvente, en la presencia de una base y de una cantidad catalítica de un compuesto de paladio que comprende un ligante de fosfina monodental o bidental; b) el producto intermedio resultante de la fórmula (IVa) y (IVb) respectivamente se hidroliza con el compuesto de la fórmula (I).
ES98933622T 1997-06-19 1998-06-17 Procedimiento para la preparacion de trifluormetilacetofenona. Expired - Lifetime ES2185183T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9712999.3A GB9712999D0 (en) 1997-06-19 1997-06-19 Process for the preparation of trifluoromethyl acetophenone

Publications (1)

Publication Number Publication Date
ES2185183T3 true ES2185183T3 (es) 2003-04-16

Family

ID=10814610

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98933622T Expired - Lifetime ES2185183T3 (es) 1997-06-19 1998-06-17 Procedimiento para la preparacion de trifluormetilacetofenona.

Country Status (12)

Country Link
US (1) US6420608B1 (es)
EP (1) EP0993432B1 (es)
JP (1) JP2002504133A (es)
AT (1) ATE225762T1 (es)
AU (1) AU8337798A (es)
BR (1) BR9810169A (es)
DE (1) DE69808624T2 (es)
DK (1) DK0993432T3 (es)
ES (1) ES2185183T3 (es)
GB (1) GB9712999D0 (es)
WO (1) WO1998058895A1 (es)
ZA (1) ZA985296B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19725038B4 (de) * 1997-06-13 2007-06-06 Henkel Kgaa Emissionsarmer wäßriger Dispersions-Klebstoff und seine Verwendung
JP4649733B2 (ja) * 2000-12-04 2011-03-16 旭硝子株式会社 トリフルオロメチル基含有アセトフェノン化合物の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421730C1 (de) * 1994-06-22 1995-11-23 Hoechst Ag Verfahren zur Herstellung von aromatischen Olefinen unter Katalyse von Palladacyclen

Also Published As

Publication number Publication date
WO1998058895A1 (en) 1998-12-30
EP0993432A1 (en) 2000-04-19
ATE225762T1 (de) 2002-10-15
ZA985296B (en) 1998-12-21
AU8337798A (en) 1999-01-04
JP2002504133A (ja) 2002-02-05
DK0993432T3 (da) 2003-01-27
EP0993432B1 (en) 2002-10-09
DE69808624T2 (de) 2003-02-06
BR9810169A (pt) 2000-08-08
DE69808624D1 (de) 2002-11-14
US6420608B1 (en) 2002-07-16
GB9712999D0 (en) 1997-08-27

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