ES2185021T3 - Procedimiento para la obtencion de 4,5,6-tricloro- y de 2,4,5,6-tetracloropirimidina. - Google Patents
Procedimiento para la obtencion de 4,5,6-tricloro- y de 2,4,5,6-tetracloropirimidina.Info
- Publication number
- ES2185021T3 ES2185021T3 ES97925052T ES97925052T ES2185021T3 ES 2185021 T3 ES2185021 T3 ES 2185021T3 ES 97925052 T ES97925052 T ES 97925052T ES 97925052 T ES97925052 T ES 97925052T ES 2185021 T3 ES2185021 T3 ES 2185021T3
- Authority
- ES
- Spain
- Prior art keywords
- stage
- procedure
- obtaining
- triclor
- tetracloropirimidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
UN PROCEDIMIENTO PARA LA OBTENCION DE 4,5,6 - TRICLORO Y 2,4,5,6 - TETRACLOROPIRIMIDINA MEDIANTE LA REACCION DE 3 DIMETILAMINOPROPIONITRILO CON HCL Y CL 2 , MEDIANTE EL CUAL A) SE HACE REACCIONAR EN UNA PRIMERA ETAPA 3 DIMETILAMINOPROPIONITRILO EN UN DISOLVENTE A UNA TEMPERATURA DE -10 HASTA 55° C CON CL 2 Y B) EN UNA SEGUNDA ETAPA LA MEZCLA DE LA PRIMERA ETAPA SE HACE REACCIONAR A UNA TEMPERATURA DE POR ENCIMA DE 55° C CON CL 2 , OPCIONALMENTE EN PRESENCIA DE UN CATALIZADOR, CARACTERIZADO PORQUE A LA SEGUNDA ETAPA QUE SE REALIZA EN PRESENCIA DEL PRODUCTO DE LA PRIMERA ETAPA, EL CUAL SE ENCUENTRA EN FORMA MICROCRISTALINA CON UN TAMAÑO MEDIO DE CRISTAL DE < 10 MI M.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19623064 | 1996-06-10 | ||
DE19624418A DE19624418A1 (de) | 1996-06-10 | 1996-06-19 | Verfahren zur Herstellung von 4,5,6-Trichlor- und 2,4,5,6-Tetrachlorpyrimidin |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2185021T3 true ES2185021T3 (es) | 2003-04-16 |
Family
ID=26026433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES97925052T Expired - Lifetime ES2185021T3 (es) | 1996-06-10 | 1997-06-06 | Procedimiento para la obtencion de 4,5,6-tricloro- y de 2,4,5,6-tetracloropirimidina. |
Country Status (5)
Country | Link |
---|---|
US (2) | US6162917A (es) |
EP (1) | EP0906289B1 (es) |
JP (1) | JP2000511915A (es) |
ES (1) | ES2185021T3 (es) |
WO (1) | WO1997047605A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7798995B2 (en) * | 2008-10-10 | 2010-09-21 | Laborie Medical Technologies, Inc. | Adjustable tip needle apparatus |
CN102250016B (zh) * | 2011-05-19 | 2012-11-07 | 绍兴文理学院 | 一种4,5,6-三氯嘧啶的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670795A1 (de) * | 1967-02-09 | 1971-03-25 | Bayer Ag | 4,5,6-Trichlorpyrimidin |
DE1644203B2 (de) * | 1967-03-25 | 1977-11-17 | Bayer Ag, 5090 Leverkusen | Reaktivfarbstoffe |
DE3900917A1 (de) * | 1989-01-13 | 1990-07-19 | Bayer Ag | Verfahren zur herstellung von 4,5,6-trichlorpyrimidin |
-
1997
- 1997-06-06 JP JP10501163A patent/JP2000511915A/ja active Pending
- 1997-06-06 EP EP97925052A patent/EP0906289B1/de not_active Expired - Lifetime
- 1997-06-06 WO PCT/EP1997/002933 patent/WO1997047605A1/de active IP Right Grant
- 1997-06-06 US US09/194,983 patent/US6162917A/en not_active Expired - Fee Related
- 1997-06-06 ES ES97925052T patent/ES2185021T3/es not_active Expired - Lifetime
-
2000
- 2000-09-22 US US09/668,087 patent/US6369259B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO1997047605A1 (de) | 1997-12-18 |
US6369259B1 (en) | 2002-04-09 |
EP0906289A1 (de) | 1999-04-07 |
US6162917A (en) | 2000-12-19 |
JP2000511915A (ja) | 2000-09-12 |
EP0906289B1 (de) | 2002-10-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2128256B1 (es) | Sintesis del 1-cloro-3,3,3-trifluorpropeno y su fluoracion en 1,1,1,3,3-pentafluorpropano. | |
ES2057090T3 (es) | Un procedimiento para la preparacion de sulfonatos de olefinas internas. | |
ES2124373T3 (es) | Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico. | |
EA200201046A1 (ru) | 7- или 9-замещенные соединения тетрациклина, способ их получения (варианты), фармацевтическая композиция, способ лечения состояния, чувствительного к действию тетрациклина, у млекопитающего и реакционноспособное промежуточное производное | |
AR077416A2 (es) | Compuesto polimorfo estable de flibanserina , procedimiento industrial para su preparacion y uso del mismo para preparar medicamentos | |
ES2189768T3 (es) | Sintesis regioselectiva de derivados de rapamicina. | |
BR9508233A (pt) | Processo para a manufatura de 1,1,1,3,3-penta-fluor-propano | |
ATE435835T1 (de) | Expandierbare graphit-intercalationsverbindungen, verfahren zu ihrer hestellung und ihrer verwendung | |
ES2159919T3 (es) | Procedimiento para la preparacion de compuestos de tipo ceramidas. | |
ES2058707T3 (es) | Procedimiento para la obtencion del acido 1-aminometil-1-ciclohexanoacetico. | |
BR0005488A (pt) | Processo para a preparação de carbonato de vinileno, e o uso do mesmo | |
PT1063899E (pt) | Manufactura de muesli e produtos para refeicoes ligeiras | |
BR9913505A (pt) | Processo para a sincronização de uma estação rádio base com uma estação móvel | |
AU2003291987A1 (en) | Method for regenerating a hydrogenation catalyst | |
MY141020A (en) | Novel pparalpha and ppargamma agonists | |
ES2185021T3 (es) | Procedimiento para la obtencion de 4,5,6-tricloro- y de 2,4,5,6-tetracloropirimidina. | |
BR0114728A (pt) | Método para produzir acilfenilalanina | |
ES2185196T3 (es) | Un procedimiento para la preparacion de tetraazamacrociclos. | |
HUP0004510A1 (hu) | Eljárás L-dihidroorotsav előállítására és a vegyület alkalmazása | |
JPS5424852A (en) | Preparation of aromatic urethane compound | |
AR021005A1 (es) | Procedimiento para la preparacion de cetiminas | |
BR9909029A (pt) | Estabilização de poliisocianatos orgânicos | |
CR9174A (es) | Composiciones y procesos para preparar 13-desoxi antraciclinas | |
FI865220A0 (fi) | Foerfarande foer framstaellning av sulfinyl- och sulfonylsubstituerade 3-benzazepiner. | |
ES2090842T3 (es) | Catalizador solido de acido fosforico y procedimiento para su preparacion y para su uso. |