ES2182309T3 - Composiciones topicas. - Google Patents

Composiciones topicas.

Info

Publication number
ES2182309T3
ES2182309T3 ES98923030T ES98923030T ES2182309T3 ES 2182309 T3 ES2182309 T3 ES 2182309T3 ES 98923030 T ES98923030 T ES 98923030T ES 98923030 T ES98923030 T ES 98923030T ES 2182309 T3 ES2182309 T3 ES 2182309T3
Authority
ES
Spain
Prior art keywords
pharmaceutically acceptable
eutectic mixture
topical compositions
topical composition
continuous phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98923030T
Other languages
English (en)
Inventor
Clare Passmore
Claire Gilligan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Ireland Ltd
Original Assignee
Galen Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galen Chemicals Ltd filed Critical Galen Chemicals Ltd
Application granted granted Critical
Publication of ES2182309T3 publication Critical patent/ES2182309T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles

Abstract

La invención se refiere a una composición tópica que comprende una emulsión de al menos una fase discontinua en una fase continua, cada fase discontinua incluye una mezcla eutéctica de un primer y un segundo agente farmacológicamente activos y la fase continua es proporcionada por un excipiente farmacológicamente aceptable, la mezcla eutéctica tiene un punto de fusión por debajo de los 40º C. La composición tópica puede comprender adicionalmente, en la mezcla eutéctica, un tercer o un cuarto componente farmacológicamente aceptable.
ES98923030T 1997-05-14 1998-05-14 Composiciones topicas. Expired - Lifetime ES2182309T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE970346 1997-05-14

Publications (1)

Publication Number Publication Date
ES2182309T3 true ES2182309T3 (es) 2003-03-01

Family

ID=11041469

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98923030T Expired - Lifetime ES2182309T3 (es) 1997-05-14 1998-05-14 Composiciones topicas.

Country Status (15)

Country Link
US (1) US6841161B1 (es)
EP (1) EP0981330B1 (es)
JP (1) JP2001525820A (es)
CN (1) CN1255850A (es)
AT (1) ATE221770T1 (es)
AU (1) AU734429B2 (es)
CA (1) CA2289966A1 (es)
DE (1) DE69807065T2 (es)
DK (1) DK0981330T3 (es)
ES (1) ES2182309T3 (es)
IL (1) IL132682A (es)
NO (1) NO995573L (es)
NZ (1) NZ501235A (es)
PT (1) PT981330E (es)
WO (1) WO1998051283A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6299902B1 (en) 1999-05-19 2001-10-09 The University Of Georgia Research Foundation, Inc. Enhanced transdermal anesthesia of local anesthetic agents
US6368618B1 (en) * 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
EP1406633B1 (en) 2001-06-18 2011-10-05 Noven Pharmaceuticals, Inc. Enhanced drug delivery in transdermal systems
US6528076B2 (en) * 2001-07-06 2003-03-04 Magic Herb Corp. Topical compositions and methods for treating pain
DE10141650C1 (de) * 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US7138394B2 (en) * 2002-09-27 2006-11-21 Alpharx Inc. Vehicle for topical delivery of anti-inflammatory compounds
US20060241175A1 (en) * 2002-09-27 2006-10-26 Joseph Schwarz Vehicle for topical delivery of anti-inflammatory compounds
WO2004110458A1 (en) * 2003-05-16 2004-12-23 Board Of Regents, The University Of Texas System Phenothiazine enantiomers as agents for the prevention of bone loss
ITMI20031640A1 (it) * 2003-08-08 2005-02-09 Mipharm S P A Base per gel bioadesivi.
DE102004001093A1 (de) * 2004-01-05 2005-07-28 Liedtke, Rainer K., Dr. Zusammensetzung und Methode einer synergistischen topischen Therapie neuromuskulärer Schmerzen
EP1763370B1 (en) * 2004-06-02 2015-04-29 NeurogesX Inc. Formulations comprising capsaicin, a local anesthetic and/or an antipruritic agent for the treatment of pain
US20070048360A1 (en) * 2005-08-23 2007-03-01 R Carrara Dario N Pharmaceutical compositions with melting point depressant agents and method of making same
AU2006302237C1 (en) * 2005-10-07 2012-11-08 The University Of Alabama Multi-functional ionic liquid compositions
US20070224261A1 (en) * 2006-03-22 2007-09-27 Peter Draper Eutectic liquid drug formulation
US20080255103A1 (en) * 2007-04-12 2008-10-16 Ballay Pharmaceuticals, Inc. Antihistamine and anti-nausea pharmaceutical compositions for topical application
EA201070690A1 (ru) 2007-12-06 2010-10-29 Унилевер Н.В. Композиция для личного ухода
BRPI0819028B1 (pt) 2007-12-06 2016-09-20 Unilever Nv composição de cuidados dos cabelos/couro cabeludo e uso de uma composição
US20110092493A1 (en) * 2008-09-24 2011-04-21 Clark Levi Dose-controlled transdermal promethazine compositions and methods of use
EP2544659A2 (en) 2009-12-23 2013-01-16 Nuvo Research Inc. Highly permeating terbinafine formulation for treating onychomycosis
US8535692B2 (en) * 2010-04-21 2013-09-17 Teikoku Pharma Usa, Inc. Local anesthetic emulsion compositions and methods of making and using the same
US20130261142A1 (en) * 2010-12-15 2013-10-03 Hung-Cheng Lai Compounds used for treating cancer and the use thereof
GB201113662D0 (en) * 2011-08-08 2011-09-21 Prosonix Ltd Pharmaceutical compositions
WO2014123100A1 (ja) * 2013-02-05 2014-08-14 リンテック株式会社 貼付型表面麻酔剤
CN104548070B (zh) * 2015-01-19 2016-08-24 常州亚当生物技术有限公司 复方辣椒碱乳剂在治疗皮肤创伤的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206021A (en) * 1988-05-09 1993-04-27 Rhone-Poulenc Ag Company Stabilized oil-in-water emulsions or suspoemulsions containing pesticidal substances in both oil and water phases
GB8921710D0 (en) 1989-09-26 1989-11-08 Mentholatum Co Ltd Ibuprofen triturates and topical compositions containing same
WO1991008670A1 (en) * 1989-12-11 1991-06-27 Vincent Henry Guerrini Pesticidal composition comprising azadirachtin, dialkyltoluamide and oil (geraniol and/or citronellal)
US5525597A (en) * 1993-12-14 1996-06-11 Kalamazoo Holdings, Inc. Synergistic insecticidal compositions comprising capsicum and insecticidal use thereof
TW460296B (en) * 1994-09-01 2001-10-21 Janssen Pharmaceutica Nv Topical ketoconazole emulsion compositions without sodium sulfite
US6251405B1 (en) * 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
US5658583A (en) * 1995-07-28 1997-08-19 Zhang; Jie Apparatus and methods for improved noninvasive dermal administration of pharmaceuticals

Also Published As

Publication number Publication date
IL132682A0 (en) 2001-03-19
DE69807065T2 (de) 2003-05-08
WO1998051283A1 (en) 1998-11-19
EP0981330B1 (en) 2002-08-07
NO995573L (no) 2000-01-14
ATE221770T1 (de) 2002-08-15
JP2001525820A (ja) 2001-12-11
AU734429B2 (en) 2001-06-14
CN1255850A (zh) 2000-06-07
NO995573D0 (no) 1999-11-12
CA2289966A1 (en) 1998-11-19
DE69807065D1 (de) 2002-09-12
EP0981330A1 (en) 2000-03-01
AU7545698A (en) 1998-12-08
DK0981330T3 (da) 2002-12-02
IL132682A (en) 2004-06-20
PT981330E (pt) 2002-12-31
US6841161B1 (en) 2005-01-11
NZ501235A (en) 2001-06-29

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