ES2181774T3 - Procedimiento para producir n-terc-butil-2-piperazinocarboxamida. - Google Patents

Procedimiento para producir n-terc-butil-2-piperazinocarboxamida.

Info

Publication number
ES2181774T3
ES2181774T3 ES95916018T ES95916018T ES2181774T3 ES 2181774 T3 ES2181774 T3 ES 2181774T3 ES 95916018 T ES95916018 T ES 95916018T ES 95916018 T ES95916018 T ES 95916018T ES 2181774 T3 ES2181774 T3 ES 2181774T3
Authority
ES
Spain
Prior art keywords
butil
tert
optically active
produce
piperazinocarboxamida
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95916018T
Other languages
English (en)
Inventor
Nanao Watanabe
Yoko Tokuda
Kenichi Kikegawa
Hideki Kuranishi
Takashi Kurahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koei Chemical Co Ltd
Original Assignee
Koei Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3004495A external-priority patent/JPH083145A/ja
Priority claimed from JP7053346A external-priority patent/JPH08217759A/ja
Application filed by Koei Chemical Co Ltd filed Critical Koei Chemical Co Ltd
Application granted granted Critical
Publication of ES2181774T3 publication Critical patent/ES2181774T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

UN PROCESO PARA PRODUCIR N-TERT-BUTI-PIPERACINACARBOXAMIDA OPTICAMENTE ACTIVA, UTIL COMO, POR EJEMPLO, UN INTERMEDIARIO EN MEDICINAS CON UNA ALTA PUREZA OPTICA POR LA RESOLUCION OPTICA DE (R,S)-N-TERT-BUTIL-PIPERACINACARBOXAMIDA CON EL USO DE UN ACIDO LACTICO, MELICO O TARTARICO OPTICAMENTE ACTIVO. EL ANTIPODO RESTANTE COMO UN ANTIPODO INUTIL EN EL PASO DE LA RESOLUCION OPTICA DE ARRIBA, PUEDE SER UTILIZADO EFICAZMENTE MEDIANTE LA RACIMACION OPTICAMENTE ACTIVA DE N-TERT-BUTILPIPERACINACARBOXAMIDA EN LA PRESENCIA DE UN COMPUESTO BASICO Y EFECTUANDO OTRA VEZ LA RESOLUCION OPTICA.
ES95916018T 1994-04-22 1995-04-20 Procedimiento para producir n-terc-butil-2-piperazinocarboxamida. Expired - Lifetime ES2181774T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP10772394 1994-04-22
JP3004495A JPH083145A (ja) 1994-04-22 1995-01-25 光学活性Ｎ−ｔｅｒｔ−ブチル−２−ピペラジンカルボキサミドの製造法
JP7053346A JPH08217759A (ja) 1995-02-16 1995-02-16 光学活性Ｎ−ｔｅｒｔ−ブチル−２−ピペラジンカルボキサミドのラセミ化法

Publications (1)

Publication Number Publication Date
ES2181774T3 true ES2181774T3 (es) 2003-03-01

Family

ID=27286815

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95916018T Expired - Lifetime ES2181774T3 (es) 1994-04-22 1995-04-20 Procedimiento para producir n-terc-butil-2-piperazinocarboxamida.

Country Status (5)

Country Link
EP (1) EP0705824B1 (es)
KR (1) KR100389151B1 (es)
DE (1) DE69527683T2 (es)
ES (1) ES2181774T3 (es)
WO (1) WO1995029170A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011010579A1 (ja) * 2009-07-21 2011-01-27 住友化学株式会社 光学活性ニペコタミドの製造方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI58497C (fi) * 1973-02-10 1981-02-10 Celamerck Gmbh & Co Kg Fungicidiskt verksam n,n'-bis((1-formamido-2,2,2-triklor)etyl)-piperazin och foerfarande foer dess framstaellning
CH613205A5 (es) * 1975-06-06 1979-09-14 Hoffmann La Roche
JPH01117869A (ja) * 1987-10-30 1989-05-10 Hokuriku Seiyaku Co Ltd ２−アミノメチルピペラジン誘導体
JP3032547B2 (ja) * 1990-03-28 2000-04-17 杏林製薬株式会社 光学活性２―メチルピペラジンの分割方法
IL103613A (en) * 1991-11-08 1999-05-09 Merck & Co Inc VIH protease inhibitors, and the process of preparing intermediates and pharmaceutical preparations containing them.
TW472047B (en) * 1994-02-04 2002-01-11 Merck & Co Inc Process for making HIV protease inhibitors

Also Published As

Publication number Publication date
KR100389151B1 (ko) 2003-10-04
KR960703116A (ko) 1996-06-19
WO1995029170A1 (fr) 1995-11-02
EP0705824A1 (en) 1996-04-10
DE69527683D1 (de) 2002-09-12
EP0705824A4 (en) 1996-08-14
EP0705824B1 (en) 2002-08-07
DE69527683T2 (de) 2003-04-10

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