ES2181059T3 - Preparacion de tiazoles. - Google Patents

Preparacion de tiazoles.

Info

Publication number
ES2181059T3
ES2181059T3 ES97954817T ES97954817T ES2181059T3 ES 2181059 T3 ES2181059 T3 ES 2181059T3 ES 97954817 T ES97954817 T ES 97954817T ES 97954817 T ES97954817 T ES 97954817T ES 2181059 T3 ES2181059 T3 ES 2181059T3
Authority
ES
Spain
Prior art keywords
alkyl
halogen
formula
phenyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97954817T
Other languages
English (en)
Inventor
Thomas Pitterna
Henry Szczepanski
Peter Maienfisch
Ottmar Franz Huter
Thomas Rapold
Marcel Senn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syngenta Participations AG
Original Assignee
Syngenta Participations AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations AG filed Critical Syngenta Participations AG
Application granted granted Critical
Publication of ES2181059T3 publication Critical patent/ES2181059T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/16—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/70—Sulfur atoms
    • C07D277/74—Sulfur atoms substituted by carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A UN PROCEDIMIENTO DE PREPARACION DE UN COMPUESTO DE FORMULA (I), DONDE R ES ALQUILO C 1 C SUB,12 SUSTITUIDO O SIN SUSTITUIR, ALQUENILO C 2 C 4 , ALQUINILO C 2 - C 4 , CICLOALQUILO C 3 C 6 , ARILO O HETEROARILO, O - SR 1 ; R 1 ES ALQUILO C SUB,1 - C 12 SUSTITUIDO O SIN SUSTITUIR, ALQUENILO C SUB,2 - C 4 , ALQUINILO C 2 - C 4 , CICLOALQUILO, A RILO O HETEROARILO; Y X ES UN GRUPO SALIENTE. DICHO PROCEDIMIENTO COMPRENDE LAS SIGUIENTES FASES: A) HACER REACCIONAR UN COMPUESTO DE FORMULA (II), DONDE R ES TAL Y COMO SE DEFINE EN LA FORMULA (I), CON UN REACTIVO ELIMINADOR DE AGUA, O B) PARA LA PREPARACION DE UN COMPUESTO DE FORMULA (I), DONDE X ES HALOGENO O UN SULFONATO, HACER REACCIONAR UN COMPUESTO DE FORMULA (III), DONDE R ES TAL Y COMO SE DEFINE EN LA FORMULA (I), CON UN AGENTE DE SULFONILACION; O C) PARA LA PREPARACION DE UN COMPUESTO DE FORMULA (I), DONDE X ES HALOGENO, HACER REACCIONAR UN COMPUESTO DE FORMULA (IV), DONDE R ES TAL Y COMO SE DEFINE EN LA FORMULA (I); YDONDE R 2 Y R 3 SON, POR EJEMPLO, H, ALQUILO C 1 - C 6 , CICLOALQUILO C 3 - C 6 , FENILO O BENCILO; CON UN COMPUESTO DE FORMULA HALOGENO - C(= O) - O - ALQUILO C 1 - C 8 , HALOGENO - C(= O) - O - ARILO O HALOGENO - C(=O) - O - BENCILO. SE INCLUYEN ASIMISMO INTERMEDIARIOS PARA LA REALIZACION DE LA SINTESIS DE LOS COMPUESTOS (II) A (IV), Y UN PROCEDIMIENTO DE PREPARACION DE LOS MISMOS.
ES97954817T 1996-12-19 1997-12-17 Preparacion de tiazoles. Expired - Lifetime ES2181059T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH312596 1996-12-19

Publications (1)

Publication Number Publication Date
ES2181059T3 true ES2181059T3 (es) 2003-02-16

Family

ID=4249152

Family Applications (2)

Application Number Title Priority Date Filing Date
ES97954817T Expired - Lifetime ES2181059T3 (es) 1996-12-19 1997-12-17 Preparacion de tiazoles.
ES01129478T Expired - Lifetime ES2246985T3 (es) 1996-12-19 1997-12-17 Preparacion de tiazoles.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES01129478T Expired - Lifetime ES2246985T3 (es) 1996-12-19 1997-12-17 Preparacion de tiazoles.

Country Status (11)

Country Link
US (5) US6548676B1 (es)
EP (3) EP0946532B1 (es)
JP (1) JP4354533B2 (es)
KR (1) KR100521067B1 (es)
AT (2) ATE307807T1 (es)
AU (1) AU6205698A (es)
DE (2) DE69714076T2 (es)
DK (2) DK0946532T3 (es)
ES (2) ES2181059T3 (es)
IL (1) IL130293A0 (es)
WO (1) WO1998027075A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI359810B (en) * 2004-11-04 2012-03-11 Mitsubishi Tanabe Pharma Corp Carboxylic acid derivative containing thiazole rin
WO2016057931A1 (en) 2014-10-10 2016-04-14 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US546167A (en) * 1895-09-10 Mills
EP0192060B1 (de) * 1985-02-04 1991-09-18 Nihon Bayer Agrochem K.K. Heterocyclische Verbindungen
US5180833A (en) * 1990-03-16 1993-01-19 Takeda Chemical Industries, Ltd. Process for the preparation of chlorothiazole derivatives
US5185354A (en) * 1990-06-18 1993-02-09 Mitsubishi Kasei Corporation Pyrazolecarboxamide, insecticidal and miticidal composition, and fungicidal composition for use in agriculture and horticulture
ZA9610046B (en) * 1995-12-01 1997-07-10 Ciba Geigy Process for preparing 2-chlorothiazole compounds

Also Published As

Publication number Publication date
JP2001506255A (ja) 2001-05-15
US20030216579A1 (en) 2003-11-20
DE69714076D1 (de) 2002-08-22
US7161011B2 (en) 2007-01-09
DK1201662T3 (da) 2006-02-13
DE69734479D1 (de) 2005-12-01
WO1998027075A1 (en) 1998-06-25
US20070055063A1 (en) 2007-03-08
EP0946532B1 (en) 2002-07-17
US20090198054A1 (en) 2009-08-06
JP4354533B2 (ja) 2009-10-28
EP0946532A1 (en) 1999-10-06
KR100521067B1 (ko) 2005-10-14
US7538229B2 (en) 2009-05-26
US6548676B1 (en) 2003-04-15
US20080076920A1 (en) 2008-03-27
AU6205698A (en) 1998-07-15
US7795442B2 (en) 2010-09-14
DE69714076T2 (de) 2003-03-06
ATE220670T1 (de) 2002-08-15
EP1577307A3 (en) 2009-04-29
DE69734479T2 (de) 2006-06-29
EP1201662B1 (en) 2005-10-26
IL130293A0 (en) 2000-06-01
ATE307807T1 (de) 2005-11-15
US7323564B2 (en) 2008-01-29
EP1577307A2 (en) 2005-09-21
KR20000069614A (ko) 2000-11-25
EP1201662A1 (en) 2002-05-02
ES2246985T3 (es) 2006-03-01
DK0946532T3 (da) 2002-11-11

Similar Documents

Publication Publication Date Title
WO1997047270A3 (en) Novel anti-viral compounds
JPS57108092A (en) 7-oxo-4-thia-1-aza(3,2,0)heptane and 7-oxo-4-thia-1-aza(3,2,0)hept-2-ene derivative
GR3006406T3 (es)
ATE145400T1 (de) Naphthalin-derivate
IE780625L (en) Imidazo-triazines
ES2090099T3 (es) Derivados de piranil-cianoguanidina.
GR3015831T3 (en) Anti-amnesic pyrrolidine derivatives.
HU9401420D0 (en) Collagenase inhibitor
DE3783754D1 (de) Prolin-derivate.
HU9203284D0 (en) Method for producing thiazolidine-2,4-dione derivatives and medical preparatives containing these compounds
IE780922L (en) 1,3,5-s-HEXAHYDROSUBSTITUTED TRIAZINES
ES2181059T3 (es) Preparacion de tiazoles.
CA2092919A1 (en) Epoxysuccinamic acid derivatives
AU5910690A (en) Method of treating diabetes mellitus
DK0527232T3 (da) Thiazolidin-2,4-dion-derivat, salt deraf og fremstilling deraf
CY1742A (en) Mitomycin analogs a process for preparing them and pharmaceutical compositions
AU553765B2 (en) Biologically active heterocyclic hydroximidates and thiolhydroximidates and carbamate ester derivatives thereof
AU1317688A (en) Benzoxazine derivatives and processes for preparation thereof