ES2177755T3 - Nuevos preparados farmaceuticos a base de peptido de activacion de proteina c. - Google Patents
Nuevos preparados farmaceuticos a base de peptido de activacion de proteina c.Info
- Publication number
- ES2177755T3 ES2177755T3 ES96901265T ES96901265T ES2177755T3 ES 2177755 T3 ES2177755 T3 ES 2177755T3 ES 96901265 T ES96901265 T ES 96901265T ES 96901265 T ES96901265 T ES 96901265T ES 2177755 T3 ES2177755 T3 ES 2177755T3
- Authority
- ES
- Spain
- Prior art keywords
- protein
- activation peptide
- pharmaceutical preparations
- new pharmaceutical
- preparations based
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
SE PRESENTA EL USO DEL PEPTIDO DE ACTIVACION DE LA PROTEINA C PARA PREPARAR UNA PREPARACION FARMACEUTICA QUE POSEE UNA ACTIVIDAD ANTINOCICEPTIVA. ESTA PREPARACION FARMACEUTICA ES UTIL EN EL TRATAMIENTO DE ESTADOS DOLOROSOS PROVOCADOS POR PROCESOS INFLAMATORIOS AGUDOS O CRONICOS (TALES COMO ARTRITIS REUMATOIDEA, MIOSITIS, GASTRITIS, COLITIS, INFLAMACIONES EN EL TRACTO UROGENITAL).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/375,777 US5571786A (en) | 1990-08-16 | 1995-01-20 | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2177755T3 true ES2177755T3 (es) | 2002-12-16 |
Family
ID=23482293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96901265T Expired - Lifetime ES2177755T3 (es) | 1995-01-20 | 1996-01-12 | Nuevos preparados farmaceuticos a base de peptido de activacion de proteina c. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5571786A (es) |
EP (1) | EP0804228B1 (es) |
JP (1) | JP3330953B2 (es) |
AT (2) | ATE218368T1 (es) |
CA (1) | CA2209931A1 (es) |
DE (1) | DE69621591T2 (es) |
DK (1) | DK0804228T3 (es) |
ES (1) | ES2177755T3 (es) |
WO (1) | WO1996022108A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001526533A (ja) * | 1997-04-23 | 2001-12-18 | フラームス・インテルウニフェルシタイル・インスティチュート・フォール・ビオテヒノロヒー | λ様プロモーターを有する遺伝子の誘導性発現のための調節系 |
US6953568B1 (en) * | 1998-08-25 | 2005-10-11 | Oklahoma Medical Research Foundation | Targeting of molecules to large vessel endothelium using EPCR |
WO2000037022A2 (en) * | 1998-12-21 | 2000-06-29 | Eli Lilly And Company | Combination therapy for the treatment of sepsis |
JP2004503216A (ja) * | 2000-05-22 | 2004-02-05 | ジョンズ・ホプキンス・ユニバーシティ | 疾患を阻止するための血管移植片の遺伝子工学処理 |
AU2002302192B2 (en) * | 2001-06-13 | 2007-08-16 | Zz Biotech Llc | Treatment and composition for wound healing |
AU2002354951A1 (en) * | 2001-07-19 | 2003-03-03 | Dmi Biosciences, Inc. | Use of copper chelators to inhibit the inactivation of protein c |
CN1980948B (zh) | 2002-11-27 | 2011-08-10 | Dmi生物科学公司 | 治疗由增强磷酸化介导的疾病和病况 |
IN2014DN10075A (es) | 2012-05-31 | 2015-08-21 | Univ Kinki | |
WO2014005183A1 (en) | 2012-07-04 | 2014-01-09 | The University Of Sydney | Treatment of inflammatory skin disorders |
EP3137102B1 (en) | 2014-04-16 | 2021-07-14 | ZZ Biotech LLC | Apc for use in the treatment of abnormal cutaneous scarring |
US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU185926B (en) * | 1979-09-27 | 1985-04-28 | Agostne Kahan | Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives |
GB8319538D0 (en) * | 1983-07-20 | 1983-08-24 | Beecham Group Plc | Compounds |
US4658830A (en) * | 1984-08-08 | 1987-04-21 | Survival Technology, Inc. | Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms |
US4902614A (en) * | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
US4775624A (en) * | 1985-02-08 | 1988-10-04 | Eli Lilly And Company | Vectors and compounds for expression of human protein C |
US4849403A (en) * | 1985-05-29 | 1989-07-18 | Pentapharm Ag | Protein C activator, methods of preparation and use thereof |
US4908314A (en) * | 1987-07-02 | 1990-03-13 | American National Red Cross | Protein C activator |
US5084274A (en) * | 1987-11-17 | 1992-01-28 | Scripps Clinic And Research Foundation | Inhibition of arterial thrombotic occlusion or thromboembolism |
US5009889A (en) * | 1987-12-31 | 1991-04-23 | Oklahoma Medical Research Foundation | Treatment of dysfunctional vascular endothelium using activated protein C |
JP2739050B2 (ja) * | 1988-01-28 | 1998-04-08 | ヘキスト薬品工業株式会社 | 抗血液凝固剤 |
DE3804600A1 (de) * | 1988-02-13 | 1989-08-24 | Basf Ag | Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz |
US5093117A (en) * | 1989-01-24 | 1992-03-03 | Baxter International Inc. | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
JP2774156B2 (ja) * | 1989-09-05 | 1998-07-09 | 帝人株式会社 | ヒトプロテインcおよび/または活性化ヒトプロテインc様活性を有する蛋白 |
AT402260B (de) * | 1990-08-16 | 1997-03-25 | Immuno Ag | Protein c-hältige pharmazeutische präparation |
-
1995
- 1995-01-20 US US08/375,777 patent/US5571786A/en not_active Expired - Fee Related
-
1996
- 1996-01-12 WO PCT/EP1996/000126 patent/WO1996022108A1/en active IP Right Grant
- 1996-01-12 EP EP96901265A patent/EP0804228B1/en not_active Expired - Lifetime
- 1996-01-12 ES ES96901265T patent/ES2177755T3/es not_active Expired - Lifetime
- 1996-01-12 AT AT96901265T patent/ATE218368T1/de not_active IP Right Cessation
- 1996-01-12 JP JP52188996A patent/JP3330953B2/ja not_active Expired - Fee Related
- 1996-01-12 DK DK96901265T patent/DK0804228T3/da active
- 1996-01-12 DE DE69621591T patent/DE69621591T2/de not_active Expired - Fee Related
- 1996-01-12 CA CA002209931A patent/CA2209931A1/en not_active Abandoned
- 1996-01-12 AT AT0901196A patent/AT409822B/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69621591D1 (de) | 2002-07-11 |
DE69621591T2 (de) | 2003-01-16 |
DK0804228T3 (da) | 2002-09-23 |
JP3330953B2 (ja) | 2002-10-07 |
US5571786A (en) | 1996-11-05 |
ATA901196A (de) | 2002-04-15 |
WO1996022108A1 (en) | 1996-07-25 |
EP0804228B1 (en) | 2002-06-05 |
EP0804228A1 (en) | 1997-11-05 |
ATE218368T1 (de) | 2002-06-15 |
JPH11502508A (ja) | 1999-03-02 |
CA2209931A1 (en) | 1996-07-25 |
AT409822B (de) | 2002-11-25 |
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