ES2176565T3 - Agente auxiliar para la formacion directa de comprimidos. - Google Patents

Agente auxiliar para la formacion directa de comprimidos.

Info

Publication number
ES2176565T3
ES2176565T3 ES97111490T ES97111490T ES2176565T3 ES 2176565 T3 ES2176565 T3 ES 2176565T3 ES 97111490 T ES97111490 T ES 97111490T ES 97111490 T ES97111490 T ES 97111490T ES 2176565 T3 ES2176565 T3 ES 2176565T3
Authority
ES
Spain
Prior art keywords
tablets
auxiliary agent
direct training
weight
direct
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES97111490T
Other languages
English (en)
Inventor
Karl Dr Kolter
Siegfried Dr Lang
Peter Prof Schmidt
Anja Huhne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Application granted granted Critical
Publication of ES2176565T3 publication Critical patent/ES2176565T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PRODUCTO AUXILIAR PARA EL TABLETAJE DIRECTO QUE CONTIENE A) DE UN 75 A UN 98 % EN PESO DE UNA CELULOSA PULVERULENTA APTA PARA EL TABLETAJE B) DE UN 1 A UN 15 % EN PESO DE POLIVINILPIRROLIDONA SOLUBLE C) DE UN 0,5 A UN 10 % EN PESO DE POLIVINILPIRROLIDONA NO SOLUBLE Y RETICULADA.
ES97111490T 1996-07-16 1997-07-08 Agente auxiliar para la formacion directa de comprimidos. Expired - Lifetime ES2176565T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19628617A DE19628617A1 (de) 1996-07-16 1996-07-16 Direkttablettierhilfsmittel

Publications (1)

Publication Number Publication Date
ES2176565T3 true ES2176565T3 (es) 2002-12-01

Family

ID=7799949

Family Applications (1)

Application Number Title Priority Date Filing Date
ES97111490T Expired - Lifetime ES2176565T3 (es) 1996-07-16 1997-07-08 Agente auxiliar para la formacion directa de comprimidos.

Country Status (6)

Country Link
US (1) US5840769A (es)
EP (1) EP0819429B1 (es)
JP (1) JPH1067651A (es)
CN (1) CN1174775C (es)
DE (2) DE19628617A1 (es)
ES (1) ES2176565T3 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
SE9802973D0 (sv) * 1998-09-03 1998-09-03 Astra Ab Immediate release tablet
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
CZ293257B6 (cs) * 1998-12-23 2004-03-17 Novartis Ag Farmaceutický přípravek obsahující antagonistu receptoru AT1 pro léčení nemocí spojených s nárůstem receptorů AT1 v subepiteliální vrstvě
DE19913606A1 (de) * 1999-03-25 2000-09-28 Basf Ag Pulverförmige Solubilisationshilfsstoffe für feste pharmazeutische Darreichungsformen
EP1070741B1 (de) * 1999-07-19 2008-04-09 fit GmbH Coprozessiertes Polysaccharidprodukt mit vernetztem Polyvinylpyrrolidon
DE10005017A1 (de) * 2000-02-04 2001-08-09 Cognis Deutschland Gmbh Duftstofftabletten
JP4470343B2 (ja) * 2000-06-22 2010-06-02 ソニー株式会社 情報閲覧装置および情報出力制御方法
DE60108395T2 (de) * 2000-06-29 2005-12-22 Neuftec Ltd. Ein brennstoffzusatz
US6761905B2 (en) 2001-05-01 2004-07-13 Wei Ming Pharmaceutical Mfg. Co., Ltd. Process for the preparation of direct tabletting formulations and aids
US20040221631A1 (en) * 2002-09-05 2004-11-11 Kerrigan Kurt J. Composition for fertilizer tablet
AU2006272978B2 (en) 2005-07-26 2012-06-07 Bial - Portela & Ca, S.A. Nitrocatechol derivatives as COMT inhibitors
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
WO2008020990A1 (en) * 2006-08-09 2008-02-21 Mallinckrodt Baker, Inc. New direct compressible excipient blend
FI20080346A0 (fi) * 2008-05-09 2008-05-09 Atacama Labs Oy Prosessi lisäaineita sisältävän tabletin valmistamiseksi
DK2481410T3 (en) 2007-01-31 2016-10-24 Bial - Portela & Ca S A Nitrocatecholderivater as COMT inhibitors administered in a specific dosage regimen
WO2009048557A1 (en) * 2007-10-10 2009-04-16 Mallinckrodt Baker, Inc. Directly compressible high functionality granular microcrystalline cellulose based excipient, manufacturing process and use thereof
US20100055180A1 (en) * 2007-10-10 2010-03-04 Mallinckrodt Baker, Inc. Directly Compressible Granular Microcrystalline Cellulose Based Excipient, Manufacturing Process and Use Thereof
DE102008014237A1 (de) * 2008-03-14 2009-09-17 J. Rettenmaier & Söhne Gmbh + Co. Kg Direktverpressbares Tablettierhilfsmittel
MX2010009610A (es) 2008-03-17 2010-09-30 Bial Portela & Ca Sa Formas de cristal de 5-[3-(2,5-dicloro-4,6-dimetil-1-oxi-piridin-3 -il)-[1,2,4]oxadiazol-5-il]-3-nitrobenceno-1,2-diol.
MX2011005168A (es) * 2008-11-19 2011-05-30 Avantor Performance Mat Inc Excipiente basado en celulosa microcristalina granular, directamente compresible, procesos de fabricacion y uso del mismo.
US9221963B2 (en) * 2008-11-27 2015-12-29 Speciality Fibres And Materials Ltd. Absorbent material
US9144625B2 (en) * 2008-11-27 2015-09-29 Speciality Fibres And Materials Ltd. Cellulose ethylsulfonate-based absorbent material
AR074689A1 (es) * 2008-12-19 2011-02-02 Solvay Pharm Bv Formulaciones farmaceuticas de desintegracion rapida pre-compactadas de compuestos con baja biodisponibilidad oral. proceso de preparacion
WO2010114404A1 (en) 2009-04-01 2010-10-07 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ，エス．アー． カテコール−ｏ−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
CN104125831A (zh) * 2012-02-29 2014-10-29 老笃制药株式会社 固体组合物
CN102773942B (zh) * 2012-07-23 2015-07-01 北京中科日升科技有限公司 一种改性淀粉的处理方法
CN105324163B (zh) 2013-06-28 2017-10-31 陶氏环球技术有限责任公司 用于制造化合物的防积垢蒸馏塔和方法
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
CA2937365C (en) 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2255263C3 (de) * 1972-11-11 1975-06-05 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von unlöslichen, vernetzten, nur wenig quellbaren Polymerisaten des N-Vinylpyrrolidon-(2)
DE3505433A1 (de) * 1985-02-16 1986-08-21 Basf Ag, 6700 Ludwigshafen Direkttablettierhilfsmittel
DE3506276C1 (de) * 1985-02-22 1986-04-24 Meggle Milchindustrie Gmbh & Co Kg, 8094 Reitmehring Direkttablettiermittel
DE3776116D1 (de) * 1986-12-30 1992-02-27 American Cyanamid Co Zusammensetzung die ein polycarbophil enthaelt.

Also Published As

Publication number Publication date
DE19628617A1 (de) 1998-01-22
EP0819429B1 (de) 2002-05-08
JPH1067651A (ja) 1998-03-10
CN1174775C (zh) 2004-11-10
CN1170610A (zh) 1998-01-21
EP0819429A1 (de) 1998-01-21
US5840769A (en) 1998-11-24
DE59707194D1 (de) 2002-06-13

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