ES2176434T3 - Derivados de benzodiazepina, sales de los mismos, y farmacos que los contienen. - Google Patents
Derivados de benzodiazepina, sales de los mismos, y farmacos que los contienen.Info
- Publication number
- ES2176434T3 ES2176434T3 ES96901983T ES96901983T ES2176434T3 ES 2176434 T3 ES2176434 T3 ES 2176434T3 ES 96901983 T ES96901983 T ES 96901983T ES 96901983 T ES96901983 T ES 96901983T ES 2176434 T3 ES2176434 T3 ES 2176434T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- indicates
- substituted
- salts
- contain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
UN DERIVADO DE BENZOXACEPINA QUE TIENE LA FORMULA GENERAL (I) Y SUS SALES Y MEDICAMENTOS QUE LAS CONTIENEN COMO INGREDIENTES EFECTIVOS: EN DONDE, N ES UN NUMERO ENTERO DE 2 A 5, R1 INDICA UN ATOMO DE HIDROGENO, UN ATOMO DE HALOGENO, UN GRUPO ALQUILO INFERIOR DE C1 A C4, UN GRUPO ALCOXIALQUILO INFERIOR DE C1 A C4, UN GRUPO HALOGENOALQUIL DE C1 A C4, UN GRUPO CIANO, O UN GRUPO ESTER, R2 INDICA UN ATOMO DE HIDROGENO, UN ATOMO DE HALOGENO, UN GRUPO ALQUILO INFERIOR DE C1 A C4, UN GRUPO ALCOXI INFERIOR DE C1 A C4, O UN GRUPO HIDROXI, LA LINEA DE PUNTOS INDICA LA PRESENCIA O AUSENCIA DE UN ENLACE DE UNION, W INDICA C, CH, O CH2 O UN ATOMO DE NITROGENO, SIEMPRE QUE CUANDO W ES UN ATOMO DE NITROGENO, Z ESTA UNIDO A W Y LA LINEA DE PUNTOS INDICA LA AUSENCIA DE UN ENLACE, Y Z INDICA UN GRUPO DE ANILLO HIDROCARBURO AROMATICO SUSTITUIDO O NO-SUSTITUIDO O UN GRUPO HETEROCICLICO SUSTITUIDO O NO-SUSTITUIDO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5830795 | 1995-02-10 | ||
JP4183695 | 1995-03-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2176434T3 true ES2176434T3 (es) | 2002-12-01 |
Family
ID=26381494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96901983T Expired - Lifetime ES2176434T3 (es) | 1995-02-10 | 1996-02-09 | Derivados de benzodiazepina, sales de los mismos, y farmacos que los contienen. |
Country Status (10)
Country | Link |
---|---|
US (2) | US6187769B1 (es) |
EP (1) | EP0755930B1 (es) |
JP (2) | JP3164584B2 (es) |
KR (1) | KR100408379B1 (es) |
AU (1) | AU709133B2 (es) |
CA (1) | CA2187541C (es) |
DE (1) | DE69622648T2 (es) |
ES (1) | ES2176434T3 (es) |
HU (1) | HUP9602774A3 (es) |
WO (1) | WO1996024594A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0001300A3 (en) * | 1997-05-22 | 2002-01-28 | Daiichi Asubio Pharma Co Ltd | Method of production and method of separation of 2,4'-dipyridil derivatives and methods of production of benzoxazepine derivatives and salts thereof |
CN1089760C (zh) * | 1997-07-14 | 2002-08-28 | 三得利株式会社 | 4-取代-3-卤代-1,4-苯并氧氮杂䓬衍生物及其盐的制备方法 |
DE10031391A1 (de) * | 2000-07-03 | 2002-02-07 | Knoll Ag | Bicyclische Verbindungen und ihre Verwendung zur Prophylaxe und Therapie der zerebralen Ischämie |
CA2682519A1 (en) | 2007-04-18 | 2008-11-06 | Kissei Pharmaceutical Co., Ltd. | Fused heterocyclic derivative, pharmaceutical composition comprising the derivative, and use of the composition for medical purposes |
US20100204202A1 (en) * | 2007-11-30 | 2010-08-12 | Asubio Pharma Co., Ltd. | Drug for alleviating motor complications or psychiatric symptoms of parkinson's disease |
WO2023192430A1 (en) * | 2022-03-30 | 2023-10-05 | University Of Florida Research Foundation, Incorported | Compounds for treating psychostimulant misuse |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE68918832T2 (de) * | 1988-12-28 | 1995-02-09 | Suntory Ltd | Benzoxazepinderivate. |
JP2865341B2 (ja) * | 1988-12-28 | 1999-03-08 | サントリー株式会社 | ベンゾオキサゼピン誘導体 |
JP2935541B2 (ja) * | 1990-06-28 | 1999-08-16 | サントリー株式会社 | 縮合複素環化合物 |
JP3112728B2 (ja) * | 1991-08-21 | 2000-11-27 | サントリー株式会社 | 2,3,4,5−テトラヒドロ−1,4−ベンゾオキサゼピン−3,5−ジオンの製造法 |
US5196428A (en) * | 1992-04-03 | 1993-03-23 | Bristol-Myers Squibb Company | Imidazo[4,5-b]qinolinyl oxy alkyl ureas |
-
1996
- 1996-02-09 WO PCT/JP1996/000294 patent/WO1996024594A1/ja active IP Right Grant
- 1996-02-09 ES ES96901983T patent/ES2176434T3/es not_active Expired - Lifetime
- 1996-02-09 CA CA002187541A patent/CA2187541C/en not_active Expired - Fee Related
- 1996-02-09 AU AU46337/96A patent/AU709133B2/en not_active Ceased
- 1996-02-09 HU HU9602774A patent/HUP9602774A3/hu unknown
- 1996-02-09 JP JP52414596A patent/JP3164584B2/ja not_active Expired - Lifetime
- 1996-02-09 EP EP96901983A patent/EP0755930B1/en not_active Expired - Lifetime
- 1996-02-09 DE DE69622648T patent/DE69622648T2/de not_active Expired - Lifetime
- 1996-02-09 KR KR1019960705669A patent/KR100408379B1/ko not_active IP Right Cessation
-
1999
- 1999-05-07 US US09/306,995 patent/US6187769B1/en not_active Expired - Lifetime
-
2000
- 2000-07-31 JP JP2000235277A patent/JP3995404B2/ja not_active Expired - Fee Related
- 2000-12-01 US US09/726,481 patent/US6337397B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2187541A1 (en) | 1996-08-15 |
HU9602774D0 (en) | 1996-11-28 |
JP3995404B2 (ja) | 2007-10-24 |
EP0755930A1 (en) | 1997-01-29 |
JP3164584B2 (ja) | 2001-05-08 |
EP0755930B1 (en) | 2002-07-31 |
DE69622648T2 (de) | 2003-02-27 |
WO1996024594A1 (fr) | 1996-08-15 |
DE69622648D1 (de) | 2002-09-05 |
KR100408379B1 (ko) | 2004-04-03 |
EP0755930A4 (en) | 1998-06-10 |
KR970702272A (ko) | 1997-05-13 |
AU709133B2 (en) | 1999-08-19 |
JP2001058989A (ja) | 2001-03-06 |
CA2187541C (en) | 2008-04-08 |
HUP9602774A3 (en) | 1998-12-28 |
AU4633796A (en) | 1996-08-27 |
US6337397B1 (en) | 2002-01-08 |
HUP9602774A2 (en) | 1997-11-28 |
US6187769B1 (en) | 2001-02-13 |
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