ES2176262T3 - Acido 2-arilalquil-o arilalquenil-ciclopentano heptenoico, y derivados como agentes terapeuticos. - Google Patents

Acido 2-arilalquil-o arilalquenil-ciclopentano heptenoico, y derivados como agentes terapeuticos.

Info

Publication number
ES2176262T3
ES2176262T3 ES94931938T ES94931938T ES2176262T3 ES 2176262 T3 ES2176262 T3 ES 2176262T3 ES 94931938 T ES94931938 T ES 94931938T ES 94931938 T ES94931938 T ES 94931938T ES 2176262 T3 ES2176262 T3 ES 2176262T3
Authority
ES
Spain
Prior art keywords
therapeutic agents
derivatives
acid
heptenoico
ciclopentano
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94931938T
Other languages
English (en)
Inventor
Steven W Andrews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Sales LLC
Original Assignee
Allergan Sales LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Sales LLC filed Critical Allergan Sales LLC
Application granted granted Critical
Publication of ES2176262T3 publication Critical patent/ES2176262T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION SUMINISTRA AGENTES TERAPEUTICOS QUE COMPRENDEN ACIDO HEPTANOICO O HEPTENOICO DE CICLOPENTANO, 2-ARILALQUILO O ARILALQUENILO Y DERIVADOS DE LOS MISMOS, EN DONDE EL ACIDO CARBOXILICO DEL COMPUESTO PROGENITOR SE CONVIERTE EN UN HIDROXILO O UN GRUPO DE ESTER. ESTOS AGENTES TERAPEUTICOS SON POTENTES HIPOTENSORES OCULARES ASI COMO TIENEN OTROS USOS TERAPEUTICOS.
ES94931938T 1993-10-28 1994-10-20 Acido 2-arilalquil-o arilalquenil-ciclopentano heptenoico, y derivados como agentes terapeuticos. Expired - Lifetime ES2176262T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/144,968 US5486540A (en) 1993-10-28 1993-10-28 Cyclopentane heptanoic or heptenoic acid, 2-arylalkyl or arylalkenyl and derivatives as therapeutic agents

Publications (1)

Publication Number Publication Date
ES2176262T3 true ES2176262T3 (es) 2002-12-01

Family

ID=22510998

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94931938T Expired - Lifetime ES2176262T3 (es) 1993-10-28 1994-10-20 Acido 2-arilalquil-o arilalquenil-ciclopentano heptenoico, y derivados como agentes terapeuticos.

Country Status (9)

Country Link
US (1) US5486540A (es)
EP (1) EP0725643B1 (es)
JP (1) JPH09506081A (es)
AT (1) ATE216890T1 (es)
AU (1) AU8084494A (es)
CA (1) CA2175076A1 (es)
DE (1) DE69430538T2 (es)
ES (1) ES2176262T3 (es)
WO (1) WO1995011682A2 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5258698A (en) 1996-11-12 1998-06-03 Alcon Laboratories, Inc. 15-ketal prostaglandins for the treatment of glaucoma or ocular hypertension
US20040097592A1 (en) * 2000-09-13 2004-05-20 Kenji Morishima Eye drops
US7842727B2 (en) * 2001-03-27 2010-11-30 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US7312247B2 (en) 2001-03-27 2007-12-25 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US8026280B2 (en) 2001-03-27 2011-09-27 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors
US6495719B2 (en) 2001-03-27 2002-12-17 Circagen Pharmaceutical Histone deacetylase inhibitors
US7057057B2 (en) * 2002-05-22 2006-06-06 Errant Gene Therapeutics, Llc Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
JP2006508986A (ja) * 2002-11-20 2006-03-16 エルラント ゲネ セラペウチクス エルエルシー ヒストンデアセチラーゼ阻害剤による肺細胞の治療方法
EP1666043B1 (en) * 2003-07-31 2009-12-02 Santen Pharmaceutical Co., Ltd. Product containing prostaglandin
US7183310B2 (en) * 2004-08-10 2007-02-27 Allergan, Inc. Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US20060073172A1 (en) * 2004-10-01 2006-04-06 Schneider L W Stabilized ophthalmic solution for the treatment of glaucoma and lowering intraocular pressure
US20060160902A1 (en) * 2004-11-08 2006-07-20 Wiech Norbert L Histone deacetylase inhibitors
EP1825855B1 (en) * 2004-12-09 2016-08-17 Santen Pharmaceutical Co., Ltd. Product containing prostaglandin having fluorine atom in molecule
EP1829545B1 (en) * 2004-12-24 2012-05-02 Santen Pharmaceutical Co., Ltd. Prostaglandin f2 alpha derivative containing products
US7618500B2 (en) * 2005-11-14 2009-11-17 Lawrence Livermore National Security, Llc Corrosion resistant amorphous metals and methods of forming corrosion resistant amorphous metals
JPWO2007097205A1 (ja) * 2006-02-02 2009-07-09 憲次 吉田 点眼剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA747723B (en) * 1974-12-11 1976-11-24 Pfizer 11-desoxy-15-substituted-omega-pentanor prostaglandins
GB1522130A (en) * 1974-11-01 1978-08-23 May & Baker Ltd Cyclopentane derivatives
JPS53135956A (en) * 1978-02-04 1978-11-28 Pfizer 111deoxyyomegaapentanol prostaglandin
US4599353A (en) * 1982-05-03 1986-07-08 The Trustees Of Columbia University In The City Of New York Use of eicosanoids and their derivatives for treatment of ocular hypertension and glaucoma
DE3220156C2 (de) * 1982-05-28 1990-01-25 Heida Houston Tex. Thurlow Mit Metallgriffen, insbesondere Edelstahlgriffen, versehenes Koch- und Bratgeschirr mit Deckel
ES2213504T1 (es) * 1988-09-06 2004-09-01 Pfizer Health Ab Derivados de prostaglandina para el tratamiento del glaucoma o hipertension ocular.
US5034413A (en) * 1989-07-27 1991-07-23 Allergan, Inc. Intraocular pressure reducing 9,11-diacyl prostaglandins
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5468778A (en) * 1992-09-24 1995-11-21 Allergan, Inc. Method of lowering intraocular pressure by administering a pharmaceutical composition containing 7-(5-substituted cyclopentyl) and 7-(5-substituted-cyclopentenyl) 5-heptenoic acids and derivatives

Also Published As

Publication number Publication date
DE69430538D1 (de) 2002-06-06
US5486540A (en) 1996-01-23
EP0725643B1 (en) 2002-05-02
WO1995011682A3 (en) 1995-05-18
WO1995011682A2 (en) 1995-05-04
AU8084494A (en) 1995-05-22
EP0725643A1 (en) 1996-08-14
DE69430538T2 (de) 2003-01-09
JPH09506081A (ja) 1997-06-17
CA2175076A1 (en) 1995-05-04
ATE216890T1 (de) 2002-05-15

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